-
1
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ,. Cancer statistics, 2009. CA Cancer J Clin 2009; 59: 225-249.
-
(2009)
CA Cancer J Clin
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Thun, M.J.6
-
2
-
-
51649093834
-
Recent advances in head and neck cancer
-
Haddad RI, Shin DM,. Recent advances in head and neck cancer. N Engl J Med 2008; 359: 1143-1154.
-
(2008)
N Engl J Med
, vol.359
, pp. 1143-1154
-
-
Haddad, R.I.1
Shin, D.M.2
-
3
-
-
34248350674
-
Case-control study of human papillomavirus and oropharyngeal cancer
-
D'souza G, Kreimer AR, Viscidi R, et al. Case-control study of human papillomavirus and oropharyngeal cancer. N Engl J Med 2007; 356: 1944-1956.
-
(2007)
N Engl J Med
, vol.356
, pp. 1944-1956
-
-
D'Souza, G.1
Kreimer, A.R.2
Viscidi, R.3
-
4
-
-
41449085148
-
Distinct risk factor profiles for human papillomavirus type 16-positive and human papillomavirus type 16-negative head and neck cancers
-
Gillison ML, D'souza G, Westra W, et al. Distinct risk factor profiles for human papillomavirus type 16-positive and human papillomavirus type 16-negative head and neck cancers. J Natl Cancer Inst 2008; 100: 407-420.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 407-420
-
-
Gillison, M.L.1
D'Souza, G.2
Westra, W.3
-
6
-
-
46049093437
-
Targeted therapy in head and neck cancer. State of the art 2007 and review of clinical applications
-
Langer CJ,. Targeted therapy in head and neck cancer. State of the art 2007 and review of clinical applications. Cancer 2008; 112: 2635-2645.
-
(2008)
Cancer
, vol.112
, pp. 2635-2645
-
-
Langer, C.J.1
-
7
-
-
57149121199
-
Randomized trial of postoperative reirradiation combined with chemotherapy after salvage surgery compared with salvage surgery alone in head and neck carcinoma
-
Janot F, de Raucourt D, Benhamou E, et al. Randomized trial of postoperative reirradiation combined with chemotherapy after salvage surgery compared with salvage surgery alone in head and neck carcinoma. J Clin Oncol 2008; 26: 5518-5523.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5518-5523
-
-
Janot, F.1
De Raucourt, D.2
Benhamou, E.3
-
9
-
-
0034575291
-
Efficacy of surgical salvage for advanced neck metastases after radiotherapy failure
-
Pathak I, Gilbert R, Davidson J, Brit D,. Efficacy of surgical salvage for advanced neck metastases after radiotherapy failure. J Otolaryngol 2000; 29: 340-343.
-
(2000)
J Otolaryngol
, vol.29
, pp. 340-343
-
-
Pathak, I.1
Gilbert, R.2
Davidson, J.3
Brit, D.4
-
10
-
-
33845959274
-
The effectiveness of salvage surgery after the failure of primary concomitant chemoradiation in head and neck cancer
-
Richey LM, Shores CG, George J, et al. The effectiveness of salvage surgery after the failure of primary concomitant chemoradiation in head and neck cancer. Otolaryngol Head Neck Surg 2007; 136: 98-103.
-
(2007)
Otolaryngol Head Neck Surg
, vol.136
, pp. 98-103
-
-
Richey, L.M.1
Shores, C.G.2
George, J.3
-
11
-
-
0347004535
-
Recurrent advanced (T3 or T4) head and neck squamous cell carcinoma. Is salvage possible?
-
Gleich LL, Ryzenman J, Gluckman JL, Wilson KM, Barrett WL, Redmond KP,. Recurrent advanced (T3 or T4) head and neck squamous cell carcinoma. Is salvage possible? Arch Otolaryngol Head Neck Surg 2004; 130: 35-38.
-
(2004)
Arch Otolaryngol Head Neck Surg
, vol.130
, pp. 35-38
-
-
Gleich, L.L.1
Ryzenman, J.2
Gluckman, J.L.3
Wilson, K.M.4
Barrett, W.L.5
Redmond, K.P.6
-
12
-
-
34249879012
-
Salvage surgery with free flap reconstruction: Factors affecting outcome after treatment of recurrent head and neck squamous carcinoma
-
Kim AJ, Suh JD, Sercarz JA, et al. Salvage surgery with free flap reconstruction: factors affecting outcome after treatment of recurrent head and neck squamous carcinoma. Laryngoscope 2007; 117: 1019-1023.
-
(2007)
Laryngoscope
, vol.117
, pp. 1019-1023
-
-
Kim, A.J.1
Suh, J.D.2
Sercarz, J.A.3
-
13
-
-
34249340144
-
Salvage reirradiation for recurrent head and neck cancer
-
Lee N, Chan K, Bekelman JE, et al. Salvage reirradiation for recurrent head and neck cancer. Int J Radiat Oncol Biol Phys 2007; 68: 731-740.
-
(2007)
Int J Radiat Oncol Biol Phys
, vol.68
, pp. 731-740
-
-
Lee, N.1
Chan, K.2
Bekelman, J.E.3
-
14
-
-
58149352991
-
IMRT reirradiation of head and neck cancer-disease control and morbidity outcomes
-
Sulman EP, Schwartz DL, Le TT, et al. IMRT reirradiation of head and neck cancer-disease control and morbidity outcomes. Int J Radiat Oncol Biol Phys 2009; 73: 399-409.
-
(2009)
Int J Radiat Oncol Biol Phys
, vol.73
, pp. 399-409
-
-
Sulman, E.P.1
Schwartz, D.L.2
Le, T.T.3
-
15
-
-
0026569931
-
A phase III randomized study comparing cisplatin and fluorouracil as single agents and in combination for advanced squamous cell carcinoma of the head and neck
-
Jacobs C, Lyman G, Velez-Garcia E, et al. A phase III randomized study comparing cisplatin and fluorouracil as single agents and in combination for advanced squamous cell carcinoma of the head and neck. J Clin Oncol 1992; 10: 257-263.
-
(1992)
J Clin Oncol
, vol.10
, pp. 257-263
-
-
Jacobs, C.1
Lyman, G.2
Velez-Garcia, E.3
-
16
-
-
0026645077
-
Randomized comparison of cisplatin plus fluorouracil and carboplatin plus fluorouracil versus methotrexate in advanced squamous-cell carcinoma of the head and neck: A Southwest Oncology Group study
-
Forastiere AA, Metch B, Schuller DE, et al. Randomized comparison of cisplatin plus fluorouracil and carboplatin plus fluorouracil versus methotrexate in advanced squamous-cell carcinoma of the head and neck: a Southwest Oncology Group study. J Clin Oncol 1992; 10: 1245-1251.
-
(1992)
J Clin Oncol
, vol.10
, pp. 1245-1251
-
-
Forastiere, A.A.1
Metch, B.2
Schuller, D.E.3
-
17
-
-
33144461661
-
Phase III randomized trial of cisplatin plus placebo compared with cisplatin plus cetuximab in metastatic/recurrent head and neck cancer: An Eastern Cooperative Oncology Group study
-
Burtness B, Goldwasser MA, Flood W, Mattar B, Forastiere AA,. Phase III randomized trial of cisplatin plus placebo compared with cisplatin plus cetuximab in metastatic/recurrent head and neck cancer: an Eastern Cooperative Oncology Group study. J Clin Oncol 2005; 23: 8646-8654.
-
(2005)
J Clin Oncol
, vol.23
, pp. 8646-8654
-
-
Burtness, B.1
Goldwasser, M.A.2
Flood, W.3
Mattar, B.4
Forastiere, A.A.5
-
18
-
-
51649085865
-
Platinum-based chemotherapy plus cetuximab in head and neck cancer
-
Vermorken JB, Mesia R, Rivera F, et al. Platinum-based chemotherapy plus cetuximab in head and neck cancer. N Engl J Med 2008; 359: 1116-1127.
-
(2008)
N Engl J Med
, vol.359
, pp. 1116-1127
-
-
Vermorken, J.B.1
Mesia, R.2
Rivera, F.3
-
19
-
-
84874105347
-
Panitumumab with cisplatin and 5-FU as 1st-line treatment of recurrent or metastatic SCCHN: The phase 3 SPECTRUM study
-
Abstract LBA26
-
Vermorken JB,. Panitumumab with cisplatin and 5-FU as 1st-line treatment of recurrent or metastatic SCCHN: the phase 3 SPECTRUM study. Ann Oncol (ESMO) 2010; 21: Abstract LBA26.
-
(2010)
Ann Oncol (ESMO)
, vol.21
-
-
Vermorken, J.B.1
-
20
-
-
84874117650
-
Pemetrexed in combination with cisplatin versus cisplatin plus placebo in patients with recurrent or metastatic squamous cell carcinoma of the head and neck: A randomized phase III study
-
Abstract 1003O
-
Urba SG,. Pemetrexed in combination with cisplatin versus cisplatin plus placebo in patients with recurrent or metastatic squamous cell carcinoma of the head and neck: a randomized phase III study. Ann Oncol (ESMO) 2010; 21:Abstract 1003O.
-
(2010)
Ann Oncol (ESMO)
, vol.21
-
-
Urba, S.G.1
-
21
-
-
20644452264
-
Randomized phase III evaluation of cisplatin plus fluorouracil versus cisplatin plus paclitaxel in advanced head and neck cancer (E1395): An intergroup trial of the Eastern Cooperative Oncology Group
-
Gibson MK, Li Y, Murphy B, et al. Randomized phase III evaluation of cisplatin plus fluorouracil versus cisplatin plus paclitaxel in advanced head and neck cancer (E1395): an intergroup trial of the Eastern Cooperative Oncology Group. J Clin Oncol 2005; 23: 3562-3567.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3562-3567
-
-
Gibson, M.K.1
Li, Y.2
Murphy, B.3
-
22
-
-
0032478998
-
Levels of TGF-α and EGFR protein in head and neck squamous cell carcinoma and patient survival
-
Rubin Grandis J, Melhem MF, Gooding WE, et al. Levels of TGF-α and EGFR protein in head and neck squamous cell carcinoma and patient survival. J Natl Cancer Inst 1998; 90: 824-832.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 824-832
-
-
Rubin Grandis, J.1
Melhem, M.F.2
Gooding, W.E.3
-
23
-
-
34250155320
-
Epidermal growth factor receptor copy number alterations correlate with poor clinical outcome in patients with head and neck squamous cancer
-
Temam S, Kawaguchi H, El-Naggar AK, et al. Epidermal growth factor receptor copy number alterations correlate with poor clinical outcome in patients with head and neck squamous cancer. J Clin Oncol 2007; 25: 2164-2170.
-
(2007)
J Clin Oncol
, vol.25
, pp. 2164-2170
-
-
Temam, S.1
Kawaguchi, H.2
El-Naggar, A.K.3
-
24
-
-
17444403242
-
Structural basis for inhibition of the epidermal growth factor receptor by cetuximab
-
Li S, Schmitz KR, Jeffrey PD, Wiltzius PD, Kussie P, Ferguson KM,. Structural basis for inhibition of the epidermal growth factor receptor by cetuximab. Cancer Cell 2005; 7: 301-311.
-
(2005)
Cancer Cell
, vol.7
, pp. 301-311
-
-
Li, S.1
Schmitz, K.R.2
Jeffrey, P.D.3
Wiltzius, P.D.4
Kussie, P.5
Ferguson, K.M.6
-
25
-
-
65549139376
-
FcγRIIIa polymorphisms and cetuximab induced cytotoxicity in squamous cell carcinoma of the head and neck
-
Taylor RJ, Chan SL, Wood A, et al. FcγRIIIa polymorphisms and cetuximab induced cytotoxicity in squamous cell carcinoma of the head and neck. Cancer Immunol Immunother 2009; 58: 997-1006.
-
(2009)
Cancer Immunol Immunother
, vol.58
, pp. 997-1006
-
-
Taylor, R.J.1
Chan, S.L.2
Wood, A.3
-
26
-
-
32144433159
-
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
-
Bonner JA, Harari PM, Giralt J, et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 2006; 354: 567-578.
-
(2006)
N Engl J Med
, vol.354
, pp. 567-578
-
-
Bonner, J.A.1
Harari, P.M.2
Giralt, J.3
-
27
-
-
80053368876
-
A randomized phase III trial (RTOG 0522) of concurrent accelerated radiation plus cisplatin with or without cetuximab for stage III-IV head and neck squamous cell carcinomas (HNC)
-
Abstract 5500
-
Ang KK, et al. A randomized phase III trial (RTOG 0522) of concurrent accelerated radiation plus cisplatin with or without cetuximab for stage III-IV head and neck squamous cell carcinomas (HNC). J Clin Oncol 2011; 29 (Suppl 15s):Abstract 5500.
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL. 15S
-
-
Ang, K.K.1
-
28
-
-
77956703721
-
Quality of life of patients receiving platinum-based chemotherapy plus cetuximab first line for recurrent and/or metastatic squamous cell carcinoma of the head and neck
-
Mesia R, Rivera F, Kawecki A, et al. Quality of life of patients receiving platinum-based chemotherapy plus cetuximab first line for recurrent and/or metastatic squamous cell carcinoma of the head and neck. Ann Oncol 2010; 21: 1967-1973.
-
(2010)
Ann Oncol
, vol.21
, pp. 1967-1973
-
-
Mesia, R.1
Rivera, F.2
Kawecki, A.3
-
29
-
-
1842772526
-
Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell carcinoma of the head and neck
-
Soulieres D, Senzer NN, Vokes EE, Hidalgo M, Agarwala SS, Siu LL,. Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell carcinoma of the head and neck. J Clin Oncol 2004; 22: 77-85.
-
(2004)
J Clin Oncol
, vol.22
, pp. 77-85
-
-
Soulieres, D.1
Senzer, N.N.2
Vokes, E.E.3
Hidalgo, M.4
Agarwala, S.S.5
Siu, L.L.6
-
30
-
-
0037674062
-
Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck
-
Cohen EEW, Rosen F, Stadler WM, et al. Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck. J Clin Oncol 2003; 21: 1980-1987.
-
(2003)
J Clin Oncol
, vol.21
, pp. 1980-1987
-
-
Cohen, E.E.W.1
Rosen, F.2
Stadler, W.M.3
-
31
-
-
64649097892
-
Phase III study of gefitinib 250 compared with intravenous methotrexate for recurrent squamous cell carcinoma of the head and neck
-
Stewart JS, Cohen EE, Licitra L, et al. Phase III study of gefitinib 250 compared with intravenous methotrexate for recurrent squamous cell carcinoma of the head and neck. J Clin Oncol 27: 2009; 1864-1871.
-
(2009)
J Clin Oncol
, vol.27
, pp. 1864-1871
-
-
Stewart, J.S.1
Cohen, E.E.2
Licitra, L.3
-
32
-
-
70350637945
-
A phase III randomized, placebo-controlled trial of docetaxel (D) with or without gefitinib (G) in recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN): A trial of the Eastern Cooperative Oncology Group
-
Abstract 6011
-
Argiris A, Ghebremichael M, Gilbert J, Burtness B, Forastiere A,. A phase III randomized, placebo-controlled trial of docetaxel (D) with or without gefitinib (G) in recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN): a trial of the Eastern Cooperative Oncology Group. J Clin Oncol 2009; 27 (Suppl 303s):Abstract 6011.
-
(2009)
J Clin Oncol
, vol.27
, Issue.SUPPL. 303S
-
-
Argiris, A.1
Ghebremichael, M.2
Gilbert, J.3
Burtness, B.4
Forastiere, A.5
-
33
-
-
84874111843
-
Effect of lapatinib monotherapy on apoptosis and proliferation: Results of a phase II randomised study in patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN)
-
Abstract 6880
-
Del Campo JM, Sebastian P, Hitt R, et al. Effect of lapatinib monotherapy on apoptosis and proliferation: results of a phase II randomised study in patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN). ESMO 2008:Abstract 6880.
-
(2008)
ESMO
-
-
Del Campo, J.M.1
Sebastian, P.2
Hitt, R.3
-
34
-
-
77952329996
-
EORTC 24051: Unexpected side effects of a phase i study of TPF induction chemotherapy (IC) followed by chemoradiation (CRT) with lapatinib (LAP), a dual EGFR/ErbB2 inhibitor, in patients with locally advanced larynx and hypopharynx squamous cell carcinoma (LA-LxHxSCC)
-
Abstract 6017
-
Specenier PM, Lalami Y, Vermorken J, et al. EORTC 24051: Unexpected side effects of a phase I study of TPF induction chemotherapy (IC) followed by chemoradiation (CRT) with lapatinib (LAP), a dual EGFR/ErbB2 inhibitor, in patients with locally advanced larynx and hypopharynx squamous cell carcinoma (LA-LxHxSCC). J Clin Oncol 2009; 27 (Suppl 15s):Abstract 6017.
-
(2009)
J Clin Oncol
, vol.27
, Issue.SUPPL. 15S
-
-
Specenier, P.M.1
Lalami, Y.2
Vermorken, J.3
-
35
-
-
33748636081
-
A phase II study of lapatinib (GW572016) in recurrent/metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN)
-
Abstract 5568
-
Abidoye OO, Cohen EE, Wong SJ, et al. A phase II study of lapatinib (GW572016) in recurrent/metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN). J Clin Oncol 2006; 24 (Suppl 18S):Abstract 5568.
-
(2006)
J Clin Oncol
, vol.24
, Issue.SUPPL. 18S
-
-
Abidoye, O.O.1
Cohen, E.E.2
Wong, S.J.3
-
36
-
-
78650597089
-
IgG isotype, glycosylation, and EGFR expression determine the induction of antibody-dependent cellular cytotoxicity in vitro by cetuximab
-
Patel D, Guo X, Ng S, et al. IgG isotype, glycosylation, and EGFR expression determine the induction of antibody-dependent cellular cytotoxicity in vitro by cetuximab. Hum Antibodies 2010; 19: 89-99.
-
(2010)
Hum Antibodies
, vol.19
, pp. 89-99
-
-
Patel, D.1
Guo, X.2
Ng, S.3
-
37
-
-
79952767715
-
Phase i PK/PD study of RO5083945 (GA201), the first glycoengineered anti-EGFR monoclonal antibody (mAb) with optimized antibody dependent cellular cytotoxicity (ADCC)
-
Abstract 2522
-
Markman B, Gomez-Roca C, Cervantes-Ruiperez A, et al. Phase I PK/PD study of RO5083945 (GA201), the first glycoengineered anti-EGFR monoclonal antibody (mAb) with optimized antibody dependent cellular cytotoxicity (ADCC). J Clin Oncol 2010; 28 (Suppl 15s):Abstract 2522.
-
(2010)
J Clin Oncol
, vol.28
, Issue.SUPPL. 15S
-
-
Markman, B.1
Gomez-Roca, C.2
Cervantes-Ruiperez, A.3
-
38
-
-
0035394833
-
Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: A role for altered tumor angiogenesis
-
Viloria-Petit A, Crombet T, Jothy S, et al. Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: a role for altered tumor angiogenesis. Cancer Res 2001; 61: 5090-5101.
-
(2001)
Cancer Res
, vol.61
, pp. 5090-5101
-
-
Viloria-Petit, A.1
Crombet, T.2
Jothy, S.3
-
39
-
-
84867261927
-
Phase II trial of cetuximab (C) and bevacizumab (B) in recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN): Final results
-
Abstract 5564
-
Argiris A, Kotsakis AP, Kim S, et al. Phase II trial of cetuximab (C) and bevacizumab (B) in recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN): final results. J Clin Oncol 2011; 29 (Suppl 15s):Abstract 5564.
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL. 15S
-
-
Argiris, A.1
Kotsakis, A.P.2
Kim, S.3
-
40
-
-
62349097073
-
Erlotinib and bevacizumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck: A phase I/II study
-
Cohen EEW, Davis DW, Karrison TG, et al. Erlotinib and bevacizumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck: a phase I/II study. Lancet Oncol 2009; 10: 247-257.
-
(2009)
Lancet Oncol
, vol.10
, pp. 247-257
-
-
Cohen, E.E.W.1
Davis, D.W.2
Karrison, T.G.3
-
41
-
-
79251477943
-
An open-label, randomized, study of h-R3mAb (nimotuzumab) in patients with advanced (stage III or IVa) squamous cell carcinoma of head and neck (SCCHN): Four-year survival results from a phase IIb study
-
Abstract 5530
-
Babu KG, Viswanath L, Reddy BK, et al. An open-label, randomized, study of h-R3mAb (nimotuzumab) in patients with advanced (stage III or IVa) squamous cell carcinoma of head and neck (SCCHN): four-year survival results from a phase IIb study. J Clin Oncol 2010; 28 (Suppl 15s):Abstract 5530.
-
(2010)
J Clin Oncol
, vol.28
, Issue.SUPPL. 15S
-
-
Babu, K.G.1
Viswanath, L.2
Reddy, B.K.3
-
42
-
-
79953905206
-
Results from a pilot study of nimotuzumab with concurrent chemoradiation in patients with locally advanced squamous cell carcinoma of head and neck
-
Abstract 5565
-
Gupta M, Madholia V, Gupta N, et al. Results from a pilot study of nimotuzumab with concurrent chemoradiation in patients with locally advanced squamous cell carcinoma of head and neck. J Clin Oncol 2010; 28 (Suppl 15s):Abstract 5565.
-
(2010)
J Clin Oncol
, vol.28
, Issue.SUPPL. 15S
-
-
Gupta, M.1
Madholia, V.2
Gupta, N.3
-
43
-
-
23744495620
-
A retrospective analysis of outcome of patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck refractory to platinum-based chemotherapy
-
León X, Hitt R, Constenla M, et al. A retrospective analysis of outcome of patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck refractory to platinum-based chemotherapy. Clin Oncol 2005; 17: 418-424.
-
(2005)
Clin Oncol
, vol.17
, pp. 418-424
-
-
León, X.1
Hitt, R.2
Constenla, M.3
-
44
-
-
34250180582
-
Open-label, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy
-
Vermorken JB, Trigo J, Hitt R, et al. Open-label, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy. J Clin Oncol 2007; 25: 2171-2177.
-
(2007)
J Clin Oncol
, vol.25
, pp. 2171-2177
-
-
Vermorken, J.B.1
Trigo, J.2
Hitt, R.3
-
45
-
-
23844523253
-
Phase II multicenter study of the antiepidermal growth factor receptor monoclonal antibody cetuximab in combination with platinum-based chemotherapy in patients with platinum-refractory metastatic and/or recurrent squamous cell carcinoma of the head and neck
-
Baselga J, Trigo JM, Bourhis J, et al. Phase II multicenter study of the antiepidermal growth factor receptor monoclonal antibody cetuximab in combination with platinum-based chemotherapy in patients with platinum-refractory metastatic and/or recurrent squamous cell carcinoma of the head and neck. J Clin Oncol 2005; 23: 5568-5577.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5568-5577
-
-
Baselga, J.1
Trigo, J.M.2
Bourhis, J.3
-
46
-
-
24944490558
-
Phase II multicenter study of the epidermal growth factor receptor antibody cetuximab and cisplatin for recurrent and refractory squamous cell carcinoma of the head and neck
-
Herbst RS, Arquette M, Shin DM, et al. Phase II multicenter study of the epidermal growth factor receptor antibody cetuximab and cisplatin for recurrent and refractory squamous cell carcinoma of the head and neck. J Clin Oncol 2005; 23: 5578-5587.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5578-5587
-
-
Herbst, R.S.1
Arquette, M.2
Shin, D.M.3
-
47
-
-
84874115213
-
A randomized, open-label phase II study of afatinib (BIBW 2992) versus cetuximab in patients with metastatic or recurrent squamous cell carcinoma of the head and neck (HNSCC) after failure of platinum-containing therapy with a cross-over period for progressing patients
-
Abstract 1010PD
-
Seiwert T, Fayette J, DelCampo JM, et al. A randomized, open-label phase II study of afatinib (BIBW 2992) versus cetuximab in patients with metastatic or recurrent squamous cell carcinoma of the head and neck (HNSCC) after failure of platinum-containing therapy with a cross-over period for progressing patients. Ann Oncol (ESMO) 2010; 21:Abstract 1010PD.
-
(2010)
Ann Oncol (ESMO)
, vol.21
-
-
Seiwert, T.1
Fayette, J.2
Delcampo, J.M.3
-
48
-
-
79953183347
-
Zalutumumab plus best supportive care versus best supportive care alone in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck after failure of platinum-based chemotherapy: An open-label, randomised phase 3 trial
-
Machiels J-P, Subramanian S, Ruzsa A, et al. Zalutumumab plus best supportive care versus best supportive care alone in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck after failure of platinum-based chemotherapy: an open-label, randomised phase 3 trial. Lancet Oncol 2011; 12: 333-343.
-
(2011)
Lancet Oncol
, vol.12
, pp. 333-343
-
-
MacHiels, J.-P.1
Subramanian, S.2
Ruzsa, A.3
-
49
-
-
68049094591
-
Antitumor activity of cediranib in patients with metastatic or recurrent head and neck cancer (HNC) or recurrent non-small cell lung cancer (NSCLC): An open-label exploratory study
-
Abstract 6023
-
Saura C, Baselga J, Herbst R, et al. Antitumor activity of cediranib in patients with metastatic or recurrent head and neck cancer (HNC) or recurrent non-small cell lung cancer (NSCLC): An open-label exploratory study. J Clin Oncol 2009; 27 (Suppl 15s):Abstract 6023.
-
(2009)
J Clin Oncol
, vol.27
, Issue.SUPPL. 15S
-
-
Saura, C.1
Baselga, J.2
Herbst, R.3
-
50
-
-
77954754601
-
Phase II evaluation of sorafenib in advanced and metastatic squamous cell carcinoma of the head and neck: Southwest Oncology Group Study S0420
-
Williamson SK, Moon J, Huang CH, et al. Phase II evaluation of sorafenib in advanced and metastatic squamous cell carcinoma of the head and neck: Southwest Oncology Group Study S0420. J Clin Oncol 2010; 28: 3330-3335.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3330-3335
-
-
Williamson, S.K.1
Moon, J.2
Huang, C.H.3
-
51
-
-
34548504810
-
Phase II trial of sorafenib in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or nasopharyngeal carcinoma
-
Elser C, Siu LL, Winquist E, et al. Phase II trial of sorafenib in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or nasopharyngeal carcinoma. J Clin Oncol 2007; 25: 3766-3773.
-
(2007)
J Clin Oncol
, vol.25
, pp. 3766-3773
-
-
Elser, C.1
Siu, L.L.2
Winquist, E.3
-
52
-
-
39649109915
-
Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial
-
Fakhry C, Westra WH, Li S, et al. Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial. J Natl Cancer Inst 2008; 100: 261-269.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 261-269
-
-
Fakhry, C.1
Westra, W.H.2
Li, S.3
-
53
-
-
0035835818
-
P16(MTS-1/CDKN2/INK4a) in cancer progression
-
Rocco JW, Sidransky D,. P16(MTS-1/CDKN2/INK4a) in cancer progression. Exp Cell Res 2001; 264: 42-55.
-
(2001)
Exp Cell Res
, vol.264
, pp. 42-55
-
-
Rocco, J.W.1
Sidransky, D.2
-
54
-
-
70350663328
-
Prognostic significance of HPV and p16 status in patients with oropharyngeal cancer treated on a large international phase III trial
-
Abstract 6004
-
Rischin D, Young R, Fisher R, et al. Prognostic significance of HPV and p16 status in patients with oropharyngeal cancer treated on a large international phase III trial. J Clin Oncol 2009; 27 (Suppl 302s):Abstract 6004.
-
(2009)
J Clin Oncol
, vol.27
, Issue.SUPPL. 302S
-
-
Rischin, D.1
Young, R.2
Fisher, R.3
-
55
-
-
70350597656
-
Biomarker potential of EGFR gene copy number by FISH in the phase III EXTREME study: Platinum-based CT plus cetuximab in first-line R/M SCCHN
-
Abstract 6005
-
Licitra L, Rolland F, Bokemeyer C, et al. Biomarker potential of EGFR gene copy number by FISH in the phase III EXTREME study: platinum-based CT plus cetuximab in first-line R/M SCCHN. J Clin Oncol 2009; 27 (Suppl 302s):Abstract 6005.
-
(2009)
J Clin Oncol
, vol.27
, Issue.SUPPL. 302S
-
-
Licitra, L.1
Rolland, F.2
Bokemeyer, C.3
-
56
-
-
76649132668
-
Restoration of p53 functions protects cells from concanavalin A-induced apoptosis
-
Amin AR, Thakur VS, Gupta K, et al. Restoration of p53 functions protects cells from concanavalin A-induced apoptosis. Mol Cancer Ther 2010; 9: 471-479.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 471-479
-
-
Amin, A.R.1
Thakur, V.S.2
Gupta, K.3
-
57
-
-
0028908858
-
P53 and retinoid chemoprevention of oral carcinogenesis
-
Lippman SM, Shin DM, Lee JJ, et al. p53 and retinoid chemoprevention of oral carcinogenesis. Cancer Res 1995; 55: 16-19.
-
(1995)
Cancer Res
, vol.55
, pp. 16-19
-
-
Lippman, S.M.1
Shin, D.M.2
Lee, J.J.3
-
58
-
-
0029664754
-
P53 expressions: Predicting recurrence and second primary tumors in head and neck squamous cell carcinoma
-
Shin DM, Lee JS, Lippman SM, et al. p53 expressions: predicting recurrence and second primary tumors in head and neck squamous cell carcinoma. J Natl Cancer Inst 1996; 88: 519-529.
-
(1996)
J Natl Cancer Inst
, vol.88
, pp. 519-529
-
-
Shin, D.M.1
Lee, J.S.2
Lippman, S.M.3
-
59
-
-
0032809839
-
Adenovirus-mediated wild-type p53 gene transfer as a surgical adjuvant in advanced head and neck cancers
-
Clayman GL, Frank DK, Bruso PA, Goepfert H,. Adenovirus-mediated wild-type p53 gene transfer as a surgical adjuvant in advanced head and neck cancers. Clin Cancer Res 1999; 7: 1715-1722.
-
(1999)
Clin Cancer Res
, vol.7
, pp. 1715-1722
-
-
Clayman, G.L.1
Frank, D.K.2
Bruso, P.A.3
Goepfert, H.4
-
60
-
-
73349137611
-
Biomarkers predict p53 gene therapy efficacy in recurrent squamous cell carcinoma of the head and neck
-
Nemunaitis J, Clayman G, Agarwala SS, et al. Biomarkers predict p53 gene therapy efficacy in recurrent squamous cell carcinoma of the head and neck. Clin Cancer Res 2009; 15: 7719-7725.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7719-7725
-
-
Nemunaitis, J.1
Clayman, G.2
Agarwala, S.S.3
-
61
-
-
0033831080
-
A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer
-
Khuri FR, Nemunaitis J, Ganly I, et al. A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat Med 2000; 6: 879-885.
-
(2000)
Nat Med
, vol.6
, pp. 879-885
-
-
Khuri, F.R.1
Nemunaitis, J.2
Ganly, I.3
-
62
-
-
0033950285
-
Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small cell lung cancer
-
Nemunaitis J, Swisher SG, Timmons T, et al. Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small cell lung cancer. J Clin Oncol 2000; 18: 609-622.
-
(2000)
J Clin Oncol
, vol.18
, pp. 609-622
-
-
Nemunaitis, J.1
Swisher, S.G.2
Timmons, T.3
-
63
-
-
0033693231
-
Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: Phase II trial
-
Nemunaitis J, Ganly I, Khuri FR, et al. Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: phase II trial. Cancer Res 2000; 60: 6359-6366.
-
(2000)
Cancer Res
, vol.60
, pp. 6359-6366
-
-
Nemunaitis, J.1
Ganly, I.2
Khuri, F.R.3
-
64
-
-
77950612308
-
A phase II study of intravenous (IV) Reolysin (wild type reovirus) in the treatment of patients with bone and soft tissue sarcomas metastatic to the lung
-
Poster presented. November 5-9, Miami, FL
-
Mita A, Sankhala K, Sarantopalos J, et al. A phase II study of intravenous (IV) Reolysin (wild type reovirus) in the treatment of patients with bone and soft tissue sarcomas metastatic to the lung. Poster presented at the 15th Annual Connective Tissue Oncology Society Meeting; November 5-9, 2009; Miami, FL.
-
(2009)
15th Annual Connective Tissue Oncology Society Meeting
-
-
Mita, A.1
Sankhala, K.2
Sarantopalos, J.3
-
65
-
-
68849091846
-
Phase I/II trial of oncolytic reovirus (REOLYSIN®) in combination with carboplatin/paclitaxel in patients with advanced solid cancers
-
Poster presented. San Diego, CA
-
Karapanagiotou E, Pandha H, Hall G, et al. Phase I/II trial of oncolytic reovirus (REOLYSIN®) in combination with carboplatin/paclitaxel in patients with advanced solid cancers. Poster presented at the International Society for Biological Therapy of Cancer; 2008; San Diego, CA.
-
(2008)
International Society for Biological Therapy of Cancer
-
-
Karapanagiotou, E.1
Pandha, H.2
Hall, G.3
-
66
-
-
84874109816
-
Phase I/II trial of oncolytic reovirus (Reolysin) in combination with carboplatin/paclitaxel in patients (pts) with advanced solid cancers with emphasis on squamous cell carcinoma of the head and neck (SCCHN)
-
Poster presented at the AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics Conference; 2009; Boston, MA
-
Harrington KJ, Karapanagiotou E, Hardev P, et al. Phase I/II trial of oncolytic reovirus (Reolysin) in combination with carboplatin/paclitaxel in patients (pts) with advanced solid cancers with emphasis on squamous cell carcinoma of the head and neck (SCCHN). Poster presented at the AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics Conference; 2009; Boston, MA. Mol Cancer Ther 2009;8(12 Suppl):B242.
-
(2009)
Mol Cancer Ther
, vol.8
, Issue.12 SUPPL.
-
-
Harrington, K.J.1
Karapanagiotou, E.2
Hardev, P.3
-
67
-
-
33748435058
-
DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy
-
Olaussen KA, Dunant A, Fouret P, et al. DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy. N Engl J Med 2006; 355: 893-891.
-
(2006)
N Engl J Med
, vol.355
, pp. 893-891
-
-
Olaussen, K.A.1
Dunant, A.2
Fouret, P.3
-
68
-
-
34447573875
-
Customizing cisplatin based on quantitative excision repair cross-complementing 1 mRNA expression: A phase III trial in non-small-cell lung cancer
-
Cobo M, Isla D, Massuti B, et al. Customizing cisplatin based on quantitative excision repair cross-complementing 1 mRNA expression: a phase III trial in non-small-cell lung cancer. J Clin Oncol 2007; 25: 2747-2754.
-
(2007)
J Clin Oncol
, vol.25
, pp. 2747-2754
-
-
Cobo, M.1
Isla, D.2
Massuti, B.3
-
69
-
-
46349110628
-
ERCC1 expression as a predictive marker of squamous cell carcinoma of the head and neck treated with cisplatin-bas concurrent chemoradiation
-
Jun HJ, Ahn MJ, Kim HS, et al. ERCC1 expression as a predictive marker of squamous cell carcinoma of the head and neck treated with cisplatin-bas concurrent chemoradiation. Br J Cancer 2008; 99: 197-172.
-
(2008)
Br J Cancer
, vol.99
, pp. 197-172
-
-
Jun, H.J.1
Ahn, M.J.2
Kim, H.S.3
-
70
-
-
34447126864
-
Excision repair cross complementation group1 immunohistochemical expression predicts objective response and cancer-specific survival in patients treated with cisplatin-based induction chemotherapy for locally advanced head and neck squamous cell carcinoma
-
Handra-Luca A, Hernandez J, Mountzios G, et al. Excision repair cross complementation group1 immunohistochemical expression predicts objective response and cancer-specific survival in patients treated with cisplatin-based induction chemotherapy for locally advanced head and neck squamous cell carcinoma. Clin Cancer Res 2007; 13: 3855-3859.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 3855-3859
-
-
Handra-Luca, A.1
Hernandez, J.2
Mountzios, G.3
-
71
-
-
33750324135
-
Single-nucleotide polymorphisms in base excision repair, nucleotide excision repair, and double strand break genes as markers for response to radiotherapy in patients with stage i to II head-and-neck cancer
-
Carles J, Monzo M, Amat M, et al. Single-nucleotide polymorphisms in base excision repair, nucleotide excision repair, and double strand break genes as markers for response to radiotherapy in patients with stage I to II head-and-neck cancer. Int J Radiat Oncol Biol Phys 2006; 66: 1022-1030.
-
(2006)
Int J Radiat Oncol Biol Phys
, vol.66
, pp. 1022-1030
-
-
Carles, J.1
Monzo, M.2
Amat, M.3
-
72
-
-
70350681354
-
Mass spectrometry profile as a predictor of overall survival benefit after treatment with epidermal growth factor receptor inhibitors in head and neck squamous cell carcinoma
-
Abstract 6000
-
Chung C, Seely EH, Grigorieva J, et al. Mass spectrometry profile as a predictor of overall survival benefit after treatment with epidermal growth factor receptor inhibitors in head and neck squamous cell carcinoma. J Clin Oncol 2009; 27 (Suppl 15s):Abstract 6000.
-
(2009)
J Clin Oncol
, vol.27
, Issue.SUPPL. 15S
-
-
Chung, C.1
Seely, E.H.2
Grigorieva, J.3
-
73
-
-
65649087923
-
Examining expression of folate receptor in squamous cell carcinoma of the head and neck as a target for a novel nanotherapeutic drug
-
Saba NF, Wang X, Müller S, et al. Examining expression of folate receptor in squamous cell carcinoma of the head and neck as a target for a novel nanotherapeutic drug. Head Neck 2009; 31: 475-481.
-
(2009)
Head Neck
, vol.31
, pp. 475-481
-
-
Saba, N.F.1
Wang, X.2
Müller, S.3
|