Aging bone marrow mesenchymal stromal cells have altered membrane glycerophospholipid composition and functionality

Journal of Lipid Research

Volumn 54, Issue 3, 2013, Pages 622-635

  Kilpinen, Lotta ^a   Tigistu Sahle, Feven ^a,b   Oja, Sofia ^a,c   Greco, Dario ^d,e   Parmar, Amarjit ^e,f   Saavalainen, Päivi ^e,f   Nikkilä, Janne ^a   Korhonen, Matti ^a,c   Lehenkari, Petri ^g,h   Käkelä, Reijo ^b   Laitinen, Saara ^a  

^a FINNISH RED CROSS BLOOD SERVICE   (Finland)

^b Institute of Biomedicine   (United States)

^c Research Program of Molecular Medicine   (United States)

^d Department of Medical Genetics   (United States)

^e UNIVERSITY OF HELSINKI   (Finland)

^f KAROLINSKA INSTITUTE   (Sweden)

^g UNIVERSITY OF OULU   (Finland)

^h Clinical Research Center   (Finland)

Author keywords

Arachidonic acid; Docosahexaenoic acid; Glycerophospholipid profi le; Lipid signaling; Mass spectrometry; Mesenchymal stem cell

Indexed keywords

GLYCEROPHOSPHOLIPID; MONOUNSATURATED FATTY ACID; OMEGA 3 FATTY ACID; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLSERINE;

ADULT; AGED; ARTICLE; BONE MARROW; CELL AGING; CELL EXPANSION; CONTROLLED STUDY; GAS CHROMATOGRAPHY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOMODULATION; LIPID METABOLISM; MASS SPECTROMETRY; MESENCHYMAL STROMA CELL; MICROARRAY ANALYSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; TELOMERE HOMEOSTASIS; WESTERN BLOTTING;

AGING; ARACHIDONIC ACID; BLOTTING, WESTERN; CELLS, CULTURED; CHROMATOGRAPHY, GAS; DOCOSAHEXAENOIC ACIDS; GLYCEROPHOSPHOLIPIDS; HUMANS; LIPID METABOLISM; MASS SPECTROMETRY; MESENCHYMAL STROMAL CELLS; TELOMERE;

EID: 84874103676     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M030650     Document Type: Article

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