Differential expression of biofunctional GM1 and GM3 gangliosides within the plastic-adherent multipotent mesenchymal stromal cell population

Cytotherapy

Volumn 12, Issue 2, 2010, Pages 131-142

  Freund, Daniel ^a,c   Fonseca, Ana Violeta ^a,c   Janich, Peggy ^a,c   Bornhäuser, Martin ^b   Corbeil, Denis ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^c CENTRE FOR GENOMIC REGULATION CRG   (Spain)

Author keywords

Ganglioside; Lipid; Membrane microdomain; Mesenchymal; Plasma membrane

Indexed keywords

GANGLIOSIDE GD2; GANGLIOSIDE GM1; GANGLIOSIDE GM3; LECTIN;

ADULT; ARTICLE; CELL CULTURE; CELL HETEROGENEITY; CELL MEMBRANE; CELL POPULATION; CELL SHAPE; CELL SIZE; CELL SURFACE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GLYCOSYLATION; HUMAN; HUMAN CELL; INDIRECT CONFOCAL LASER SCANNING FLUORESCENCE MICROSCOPY; MALE; NORMAL HUMAN; PHENOTYPE; PLASTIC ADHERENT MULTIPOTENT MESENCHYMAL STROMAL CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; STROMA CELL;

EID: 77749254973     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.3109/14653240903476438     Document Type: Article

References (57)

1. Horwitz EM, Le Blanc K, Dominici M, Mueller I, Slaper-Cortenbach I, Marini FC, et al. Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement. Cytotherapy. 2005;7:393-5.
2. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, et al. Multilineage potential of adult human mesenchymal stem cells. Science. 1999;284:143-7.
3. Friedenstein AJ, Chailakhyan RK, Latsinik NV, Panasyuk AF, Keiliss-Borok IV. Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivo. Transplantation. 1974;17:331-40.
4. Dominici M, Le Blanc K, Mueller I, Slaper-Cortenbach I, Marini F, Krause D, et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy. 2006;8:315-7.
5. Le Blanc K, Tammik C, Rosendahl K, Zetterberg E, Ringden O. HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells. Exp Hematol. 2003;31:890-6.
6. Quirici N, Soligo D, Bossolasco P, Servida F, Lumini C, Deliliers GL. Isolation of bone marrow mesenchymal stem cells by anti-nerve growth factor receptor antibodies. Exp Hematol. 2002;30:783-91.
7. Tondreau T, Meuleman N, Delforge A, Dejeneffe M, Leroy R, Massy M, et al. Mesenchymal stem cells derived from CD133-positive cells in mobilized peripheral blood and cord blood: proliferation, Oct4 expression, and plasticity. Stem Cells. 2005;23:1105-12.
8. Gregory CA, Prockop DJ, Spees JL. Non-hematopoietic bone marrow stem cells: molecular control of expansion and differentiation. Exp Cell Res. 2005;306:330-5.
9. Pozzobon M, Piccoli M, Ditadi A, Bollini S, Destro R, Andre-Schmutz I, et al. Mesenchymal stromal cells can be derived from bone marrow CD133+ cells: implications for therapy. Stem Cells Dev. 2009;18:497-510.
10. Delorme B, Ringe J, Gallay N, Le Vern Y, Kerboeuf D, Jorgensen C, et al. Specific plasma membrane protein phenotype of culture-amplified and native human bone marrow mesenchymal stem cells. Blood. 2008;111:2631-5.
11. Martinez C, Hofmann TJ, Marino R, Dominici M, Horwitz EM. Human bone marrow mesenchymal stromal cells express the neural ganglioside GD2: a novel surface marker for the identification of MSCs. Blood. 2007;109:4245-8.
12. McNiece I. Subsets of mesenchymal stromal cells. Cytotherapy. 2007;9:301-2.
13. Ho AD, Wagner W, Franke W. Heterogeneity of mesenchymal stromal cell preparations. Cytotherapy. 2008;10:320-30.
14. Bianco P, Riminucci M, Gronthos S, Robey PG. Bone marrow stromal stem cells: nature, biology, and potential applications. Stem Cells. 2001;19:180-92.
15. Tormin A, Brune JC, Olsson E, Valcich J, Neuman U, Olofsson T, et al. Characterization of bone marrow-derived mesenchymal stromal cells (MSC) based on gene expression profiling of functionally defined MSC subsets. Cytotherapy. 2009;11:114-28.
16. Prockop DJ, Sekiya I, Colter DC. Isolation and characterization of rapidly self-renewing stem cells from cultures of human marrow stromal cells. Cytotherapy. 2001;3:393-6.
17. Egana JT, Fierro FA, Krüger S, Bornhäuser M, Huss R, Lavandero S, et al. Use of human mesenchymal cells to improve vascularization in a mouse model for scaffold-based dermal regeneration. Tissue Eng Part A. 2009;15: 1191-200.
18. Ryser MF, Ugarte F, Thieme S, Bornhäuser M, Roesen-Wolff A, Brenner S. mRNA transfection of CXCR4-GFP fusion simply generated by PCR results in efficient migration of primary human mesenchymal stem cells. Tissue Eng Part C Methods. 2008;14:179-84.
19. Alberti K, Davey RE, Onishi K, George S, Salchert K, Seib FP, et al. Functional immobilization of signaling proteins enables control of stem cell fate. Nat Methods. 2008;5: 645-50.
20. Kwak DH, Yu K, Kim SM, Lee DH, Kim SM, Jung JU, et al. Dynamic changes of gangliosides expression during the differentiation of embryonic and mesenchymal stem cells into neural cells. Exp Mol Med. 2006;38:668-76.
21. Gomez-Mouton C, Abad JL, Mira E, Lacalle RA, Gallardo E, Jimenez-Baranda S, et al. Segregation of leading-edge and uropod components into specific lipid rafts during T cell polarization. Proc Natl Acad Sci USA. 2001;98:9642-7.
22. Pike LJ. Rafts defined: a report on the Keystone symposium on lipid rafts and cell function. J Lipid Res. 2006;47: 1597-8.
23. Fujita A, Cheng J, Hirakawa M, Furukawa K, Kusunoki S, Fujimoto T. Gangliosides GM1 and GM3 in the living cell membrane form clusters susceptible to cholesterol depletion and chilling. Mol Biol Cell. 2007;18:2112-22.
24. Simons K, Toomre D. Lipid rafts and signal transduction. Nat Rev Mol Cell Biol. 2000;1:31-9.
25. Sharma P, Sabharanjak S, Mayor S. Endocytosis of lipid rafts: an identity crisis. Semin Cell Dev Biol. 2002;13: 205-14.
26. Wagner W, Feldmann RE Jr, Seckinger A, Maurer MH, Wein F, Blake J, et al. The heterogeneity of human mesenchymal stem cell preparations: evidence from simultaneous analysis of proteomes and transcriptomes. Exp Hematol. 2006;34: 536-48.
27. Jeong JA, Ko KM, Park HS, Lee J, Jang C, Jeon CJ, et al. Membrane proteomic analysis of human mesenchymal stromal cells during adipogenesis. Proteomics. 2007;7:4181-91.
28. Roche S, Delorme B, Oostendorp RA, Barbet R, Caton D, Noel D, et al. Comparative proteomic analysis of human mesenchymal and embryonic stem cells: towards the definition of a mesenchymal stem cell proteomic signature. Proteomics. 2009;9:223-32.
29. Cantu L, Corti M, Brocca P, Del Favero E. Structural aspects of ganglioside-containing membranes. Biochim Biophys Acta. 2009;1788:202-8.
30. Freund D, Bauer N, Boxberger S, Feldmann S, Streller U, Ehninger G, et al. Polarization of human hematopoietic progenitors during contact with multipotent mesenchymal stromal cells: effects on proliferation and clonogenicity. Stem Cells Dev. 2006;15:815-29.
31. Oswald J, Boxberger S, Jorgensen B, Feldmann S, Ehninger G, Bornhäuser M, et al. Mesenchymal stem cells can be differentiated into endothelial cells in vitro. Stem Cells. 2004; 22:377-84.
32. Zuk PA, Zhu M, Mizuno H, Huang J, Futrell JW, Katz AJ, et al. Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng. 2001;7:211-28.
33. Weigmann A, Corbeil D, Hellwig A, Huttner WB. Prominin, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells. Proc Natl Acad Sci USA. 1997;94:12425-30.
34. Holmgren J, Lonnroth I. Oligomeric structure of cholera toxin: characteristics of the H and L subunits. J Gen Microbiol. 1975;86:49-65.
35. Tsutsumi S, Shimazu A, Miyazaki K, Pan H, Koike C, Yoshida E, et al. Retention of multilineage differentiation potential of mesenchymal cells during proliferation in response to FGF. Biochem Biophys Res Commun. 2001; 288:413-9.
36. Vyas KA, Patel HV, Vyas AA, Schnaar RL. Segregation of gangliosides GM1 and GD3 on cell membranes, isolated membrane rafts, and defined supported lipid monolayers. Biol Chem. 2001;382:241-50.
37. Röper K, Corbeil D, Huttner WB. Retention of prominin in microvilli reveals distinct cholesterol-based lipid microdomains in the apical plasma membrane. Nat Cell Biol. 2000;2:582-92.
38. Corbeil D, Röper K, Fargeas CA, Joester A, Huttner WB. Prominin: a story of cholesterol, plasma membrane protrusions and human pathology. Traffic. 2001;2:82-91.
39. Fargeas CA, Joester A, Missol-Kolka E, Hellwig A, Huttner WB, Corbeil D. Identification of novel Prominin-1/CD133 splice variants with alternative C-termini and their expression in epididymis and testis. J Cell Sci. 2004; 117:4301-11.
40. Fargeas CA, Fonseca A-V, Huttner WB, Corbeil D. Prominin-1 (CD133): from progenitor cells to human diseases. Future Lipidol. 2006;1:213-25.
41. Karbanova J, Missol-Kolka E, Fonseca AV, Lorra C, Janich P, Hollerova H, et al. The stem cell marker CD133 (Prominin-1) is expressed in various human glandular epithelia. J Histochem Cytochem. 2008;56:977-93.
42. Hakomori S. Bifunctional role of glycosphingolipids. Modulators for transmembrane signaling and mediators for cellular interactions. J Biol Chem. 1990;265:18713-6.
43. Kim SM, Jung JU, Ryu JS, Jin JW, Yang HJ, Ko K, et al. Effects of gangliosides on the differentiation of human mesenchymal stem cells into osteoblasts by modulating epidermal growth factor receptors. Biochem Biophys Res Commun. 2008;371:866-71.
44. Hardy RR, Kishimoto T, Hayakawa K. Differentiation of B cell progenitors in vitro: generation of surface IgM+ B cells, including Ly-1 B cells, from Thy-1-asialoGM1+ cells in newborn liver. Eur J Immunol. 1987;17:1769-74.
45. Freund D, Oswald J, Feldmann S, Ehninger G, Corbeil D, Bornhäuser M. Comparative analysis of proliferative potential and clonogenicity of MACS-immunomagnetic isolated CD34+ and CD133+ blood stem cells derived from a single donor. Cell Prolif. 2006;39:325-32.
46. Janich P, Corbeil D. GM1 and GM3 gangliosides highlight distinct lipid microdomains within the apical domain of epithelial cells. FEBS Lett. 2007;581:1783-7.
47. Engler AJ, Sen S, Sweeney HL, Discher DE. Matrix elasticity directs stem cell lineage specification. Cell. 2006;126:677-89.
48. Ruiz SA, Chen CS. Emergence of patterned stem cell differentiation within multicellular structures. Stem Cells. 2008;26:2921-7.
49. Bauer N, Fonseca AV, Florek M, Freund D, Jaszai J, Born-häuser M, et al. New insights into the cell biology of hematopoietic progenitors by studying Prominin-1 (CD133). Cells Tissues Organs. 2008;188:127-38.
50. Fonseca AV, Bauer N, Corbeil D. The stem cell marker CD133 meets the endosomal compartment: new insights into the cell division of hematopoietic stem cells. Blood Cells Mol Dis. 2008;41:194-5.
51. Ziulkoski AL, Andrade CM, Crespo PM, Sisti E, Trindade VM, Daniotti JL, et al. Gangliosides of myelosupportive stroma cells are transferred to myeloid progenitors and are required for their survival and proliferation. Biochem J. 2006;394:1-9.
52. Gillette JM, Larochelle A, Dunbar CE, Lippincott-Schwartz J. Intercellular transfer to signalling endosomes regulates an ex vivo bone marrow niche. Nat Cell Biol. 2009;11:303-11.
53. Mora JR, von Andrian UH. T-cell homing specificity and plasticity: new concepts and future challenges. Trends Immunol. 2006;27:235-43.
54. Barreiro O, de la Fuente H, Mittelbrunn M, Sanchez-Madrid F. Functional insights on the polarized redistribution of leukocyte integrins and their ligands during leukocyte migration and immune interactions. Immunol Rev. 2007; 218:147-64.
55. Rusnati M, Urbinati C, Tanghetti E, Dell'Era P, Lortat-Jacob H, Presta M. Cell membrane GM1 ganglioside is a functional coreceptor for fibroblast growth factor 2. Proc Natl Acad Sci USA. 2002;99:4367-72.
56. Miljan EA, Bremer EG. Regulation of growth factor receptors by gangliosides. Sci STKE. 2002;2002:re15.
57. Sorice M, Longo A, Garofalo T, Mattei V, Misasi R, Pavan A. Role of GM3-enriched microdomains in signal transduction regulation in T lymphocytes. Glycoconj J. 2004;20: 63-70.