Potential antiarrhythmic effect of methyl 3,4,5-trimethoxycinnamate, a bioactive substance from roots of polygalae radix: Suppression of triggered activities in rabbit myocytes

Biological and Pharmaceutical Bulletin

Volumn 36, Issue 2, 2013, Pages 238-244

  Zhao, Zhenghang ^a,b   Fang, Minfeng ^c   Xiao, Dandan ^a   Liu, Mei ^a   Fefelova, Nadezhda ^b   Huang, Chen ^a   Zang, Wei Jin ^a   Xie, Lai Hua ^b  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^c NORTHWEST UNIVERSITY   (China)

Author keywords

Action potential; Ca2+ transient; Cardiomyocyte; L type calcium current; Methyl 3,4,5 trimethoxycinnamate; Polygalae Radix

Indexed keywords

ANTIARRHYTHMIC AGENT; CALCIUM CHANNEL; METHYL 3,4,5 TRIMETHOXYCINNAMATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIARRHYTHMIC ACTIVITY; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CELL ACTIVITY; CELL ISOLATION; CONTROLLED STUDY; HEART DEPOLARIZATION; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CELL; HEART REPOLARIZATION; MALE; MEMBRANE CURRENT; NONHUMAN; PATCH CLAMP; POLYGALACEAE; POTASSIUM CURRENT; RABBIT; STEADY STATE;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; CINNAMATES; DRUGS, CHINESE HERBAL; MALE; MYOCYTES, CARDIAC; PLANT ROOTS; POLYGALA; RABBITS;

EID: 84874096413     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b12-00654     Document Type: Article

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