Suggested guidelines for using systemic antimicrobials in bacterial skin infections (2): Antimicrobial choice, treatment regimens and compliance

Veterinary Record

Volumn 172, Issue 6, 2013, Pages 156-160

  Beco, L ^a   Guaguere E ^b   Lorente Mendez C ^c   Noli, C ^d   Nuttall, T ^e   Vroom, M ^d  

^a Cabinet Vétérinaire   (Belgium)

^b CLINIQUE VÉTÉRINAIRE   (France)

^c Centro de Dermatología Veterinaria   (Spain)

^d Servizi Dermatologici Veterinari ^*  (Netherlands)

^e UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT;

ANIMAL; ANIMAL DISEASE; ARTICLE; BACTERIAL SKIN DISEASE; CAT; CAT DISEASE; DECISION MAKING; DOG; DOG DISEASE; PATIENT COMPLIANCE; PRACTICE GUIDELINE;

ANIMALS; ANTI-INFECTIVE AGENTS; CAT DISEASES; CATS; CHOICE BEHAVIOR; DOG DISEASES; DOGS; MEDICATION ADHERENCE; PRACTICE GUIDELINES AS TOPIC; SKIN DISEASES, BACTERIAL;

EID: 84874079786     PISSN: 00424900     EISSN: None     Source Type: Journal    
DOI: 10.1136/vr.101070     Document Type: Article

References (81)

1. ABRAHAM, E. P. & CHAIN, E. (1988) An enzyme from bacteria able to destroy penicillin. Reviews of Infectious Diseases 10, 677-678 (reprinted from Nature 146, 837).
2. ADKINSON, N. F. (1998) Beta-lactam crossreactivity. Clinical and Experimental Allergy 28, 37-40.
3. ANGARANO, D. W. & MACDONALD, J. M. (1989) Efficacy of cefadroxil in the treatment of bacterial dermatitis in dogs. Journal of the American Veterinary Medical Association 194, 57-59.
4. AUTHIER, S., PAQUETTE, D., LABRECQUE, O. & MESSIER, S. (2006) Comparison of susceptibility to antimicrobials of bacterial isolates from companion animals in a veterinary diagnostic laboratory in Canada between 2 time points 10 years apart. Canadian Veterinary Journal 47, 774-778.
5. BANNOEHR, J., BEN ZAKOUR, N. L., WALLER, A. S., GUARDABASSI, L., THODAY, K. L., VAN DEN BROEK, A. H. & FITZGERALD, J. R. (2007) Population genetic structure of the Staphylococcus intermedius group: insights into agr diversification and the emergence of methicillin-resistant strains. Journal of Bacteriology 189, 8685-8692.
6. BARTER, L. S., WATSON, A. D. & MADDISON, J. E. (1996) Owner compliance with a short term antimicrobial medication in dogs. Australian Veterinary Journal 74, 277-280.
7. BARZA, M. (1978) The nephrotoxicity of cephalosporins: an overview. Journal of Infectious Diseases 137, 560-573.
8. BERGER, S. L., SCAGLIOTTI, R. H. & LUND, E. M. (1995) A quantitative study of the effects of Tribrissen® on canine tear production. Journal of the American Animal Hospital Association 31, 236-241.
9. BIDGOOD, T. L. & PAPICH, M. G. (2005) Plasma and interstitial fluid pharmacokinetics of enrofloxacin, its metabolite ciprofloxacin, and marbofloxacin after oral administration and a constant rate intravenous infusion in dogs. Journal of Veterinary Pharmacology and Therapeutics 28, 329-341.
10. BOOTHE, D. M., BOECKH, A., SIMPSON, R. B. & DUBOSE, K. (2006) Comparison of pharmacodynamic and pharmacokinetic indices of efficacy for 5 fluoroquinolones toward pathogens of dogs and cats. Journal of Veterinary Internal Medicine 20, 1297-1306.
11. BROWN, S. A., BOUCHER, J. F., HUBBARD, V. L., PROUGH, M. J. & FLOOK, T. F. (2007) The comparative plasma pharmacokinetics of intravenous cefpodoxime sodium and oral cefpodoxime proxetil in beagle dogs. Journal of Veterinary Pharmacology Therapeutics 30, 320-326.
12. BSAVA (2011) British Small Animal Veterinary Association practice guidelines - reducing the risk from meticillin-resistant Staphylococcus aureus (MRSA) and meticillin-resistant Staphylococcus pseudintermedius (MRSP). www.bsava.com/Advice/MRSA/tabid/171/Default.aspx Accessed January 24, 2012.
13. CARLOTTI, D. N., GUAGUERE, E., PIN, D., JASMIN, P., THOMAS, E. & GUIRAL, V. (1999) Therapy of difficult cases of canine pyoderma with marbofloxacin: a report of 39 dogs. Journal of Small Animal Practice 40, 265-270.
14. CARLOTTI, D. N., JASMIN, P., GARDEY, L. & SANQUER, A. (2004) Evaluation of cephalexin intermittent therapy (weekend therapy) in the control of recurrent idiopathic pyoderma in dogs: a randomized, double-blinded, placebo-controlled study. Veterinary Dermatology 15, 8-9.
15. CARLOTTI, D. N., JASMIN, P., GUAGUÈRE, E. & THOMAS, E. (1995) Utilisation de la marbofloxacine dans le traitement des pyodermites du chien. Pratique Médicale et Chirurgicale de l'Animal de Compagnie 30, 281-293.
16. CARLOTTI, D. N. & OVAERT, P. (1988) Utilisation de l'association amoxycillineacide clavulanique dans le traitement de pyodermites chez le chien. Pratique Médicale et Chirurgicale de l'Animal de Compagnie 23, 519-522.
17. CLEENEWERCK, M. B. (2010) Update on medical and surgical gloves. European Journal of Dermatology 20, 434-442.
18. CURTIS, C. F., LAMPORT, A. I. & LLOYD, D. H. (2006) Masked, controlled study to investigate the efficacy of a Staphylococcus intermedius autogenous bacterin for the control of canine idiopathic recurrent superficial pyoderma. Veterinary Dermatology 17, 163-168.
19. DEBOER, D. J., MORIELLO, K. A., THOMAS, C. B. & SHULTZ, K. T. (1990) Evaluation of a commercial staphylococcal bacterin for management of idiopathic recurrent superficial pyoderma in dogs. American Journal of Veterinary Research 51, 636-639.
20. DE JAHAM, C. (2003) Effects of an ethyl lactate shampoo in conjunction with a systemic antibiotic in the treatment of canine superficial bacterial pyoderma in an openlabel, nonplacebo-controlled study. Veterinary Therapeutics 4, 94-100.
21. DEMANUELLE, T. C., IHRKE, P. J., BRANDT, C. M., KASS, P. H. & VULLIET, P. R. (1998) Determination of skin concentrations of enrofloxacin in dogs with pyoderma. American Journal of Veterinary Research 59, 1599-1604.
22. DEVRIESE, L. A., VANCANNEYT, M., BAELE, M., VANEECHOUTTE, M., DE GRAEF, E., SNAUWAERT, C., CLEENWERCK, I., DAWYNDT, P., SWINGS, J., DECOSTERE, A. & HAESEBROUCK, F. (2005) Staphylococcus pseudintermedius sp nov, a coagulase-positive species from animals. International Journal of Systematic and Evolutionary Microbiology 55, 1569-1573.
23. FECAVA (2010) Federation of European Companion Animal Veterinary Associations key recommendations for hygiene and infection control in veterinary practice. www.fecava.org/sites/default/files/files/Hygiene%20poster.pdf. Accessed January 24, 2012.
24. FRANK, L. A. & KUNKLE, G. A. (1993) Comparison of the efficacy of cefadroxil and generic and proprietary cephalexin in the treatment of pyoderma in dogs. Journal of the American Veterinary Medical Association 203, 530-533.
25. FRASER, M. A. & GIRLING, S. J. (2009) Bacterial carriage of computer keyboards in veterinary practices in Scotland. Veterinary Record 165, 26-27.
26. FRAZIER, D. L., THOMPSON, L., TRETTIEN, A. & EVANS, E. I. (2000) Comparison of fluoroquinolone pharmacokinetic parameters after treatment with marbofloxacin, enrofloxacin, and difloxacin in dogs. Journal of Veterinary Pharmacology and Therapeutics 23, 293-302.
27. GANIERE, J. P., MEDAILLE, C. & MANGION, C. (2005) Antimicrobial drug susceptibility of Staphylococcus intermedius clinical isolates from canine pyoderma. Journal of Veterinary Medicine B, Infectious Diseases and Veterinary Public Health 52, 25-31.
28. GHIDINI, F., PIANCASTELLI, C., TADDEI, S., GANDOLFO, E., CAVIRANI, S. & CABASSI, C. S. (2011) Antibiotic sensitivity of bacterial isolates from cases of canine dermatitis. New Microbiology 34, 403-408.
29. GIRARD, A. E., GIRARD, D., ENGLISH, A. R., GOOTZ, T. D., CIMOCHOWSKI, C. R., FAIELLA, J. A., HASKELL, S. L. & RETSEMA, J. A. (1987) Pharmacokinetic and in vivo studies with azithromycin (CP-62, 993), a new macrolide with an extended halflife and excellent tissue distribution. Antimicrobial Agents and Chemotherapy 31, 1948-1954.
30. GOUGH, A. W., KASALI, O. B., SIGLER, R. E. & BARAGI, V. (1992) Quinolone arthropathy-acute toxicity to immature articular cartilage. Toxicological Pathology 20, 436-447.
31. GRAVE, K. & TANEM, H. (1999) Compliance with short-term oral antibacterial drug treatment in dogs. Journal of Small Animal Practice 40, 158-162.
32. GUAGUÈRE, E. & MARC, J. P. (1989) Utilisation de la céfalexine dans le traitement des pyodermites. Pratique Médicale et Chirurgicale de l'Animal de Compagnie 24, 124-129.
33. HALL, I. A., CAMPBELL, K. L., CHAMBERS, M. D. & DAVIS, C. A. (1993) Effect of trimethoprim/sulfamethoxazole on thyroid function in dogs with pyoderma. Journal of the American Veterinary Medical Association 202, 1959-1962.
34. HARVEY, R. G., NOBLE, W. C. & FERGUSON, E. A. (1993) A comparison of lincomycin hydrochloride and clindamycin hydrochloride in the treatment of superficial pyoderma in dogs. Veterinary Record 132, 351-353.
35. HOLT, D., HARVEY, D. & HURLEY, R. (1993) Chloramphenicol toxicity. Adverse Drug Reactions and Toxicological Reviews 12, 83-95.
36. HORSPOOL, L. J., VAN LAAR, P., VAN DEN BOS, R. & MAWHINNEY, I. (2004) Treatment of canine pyoderma with ibafloxacin and marbofloxacin - fluoroquinolones with different pharmacokinetic profiles. Journal of Veterinary Pharmacology and Therapeutics 27, 147-153.
37. IHRKE, P. J. (1987) An overview of bacterial skin disease in the dog. British Veterinary Journal 143, 112-118.
38. IHRKE, P. J. (1996) Bacterial Skin Diseases in the Dog: a Guide to Canine Pyoderma. Veterinary Learning Systems.
39. IHRKE, P. J., PAPICH, M. G. & DEMANUELLE, T. C. (1999) The use of fluoroquinolones in veterinary dermatology. Veterinary Dermatology 10, 193-204.
40. JOHNSON, S. T., FUEGER, J. T. & GOTTSCHALL, J. L. (2007) One center's experience: the serology and drugs associated with drug-induced immune hemolytic anemia - a new paradigm. Transfusion 47, 697-702.
41. JONES, R. D., KANIA, S. A., ROHRBACH, B. W., FRANK, L. A. & BEMIS, D. A. (2007) Prevalence of oxacillin- and multidrug-resistant staphylococci in clinical samples from dogs: 1, 772 samples (2001-2005). Journal of the American Veterinary Medical Association 230, 221-227.
42. KAMPF, G. & LOFFLER, H. (2010) Hand disinfection in hospitals - benefits and risks. Journal der Deutschen Dermatologischen Gesellschaft 8, 978-983.
43. KAMPF, G., WIGGER-ALBERTI, W., SCHODER, V. & WILHELM, K. P. (2005) Emollients in a propanol-based hand rub can significantly decrease irritant contact dermatitis. Contact Dermatitis 53, 344-349.
44. KIM, T. J., NA, Y. R. & LEE, J. I. (2005) Investigations into the basis of chloramphenicol and tetracycline resistance in Staphylococcus intermedius isolates from cases of pyoderma in dogs. Journal of Veterinary Medicine B, Infectious Diseases and Veterinary Public Health 52, 119-124.
45. KUMAR, V., MADABUSHI, R., LUCCHESI, M. B. & DERENDORF, H. (2011) Pharmacokinetics of cefpodoxime in plasma and subcutaneous fluid following oral administration of cefpodoxime proxetil in male beagle dogs. Journal of Veterinary Pharmacology and Therapeutics 34, 130-135.
46. LIIPPO, J., KOUSA, P. & LAMMINTAUSTA, K. (2011) The relevance of chlorhexidine contact allergy. Contact Dermatitis 64, 229-234.
47. LLOYD, D. H., CARLOTTI, D. N., KOCH, H. J. & VAN DEN BROEK, A. H. (1997) Treatment of canine pyoderma with co-amoxyclav: a comparison of two dose rates. Veterinary Record 141, 439-441.
48. MARTÍNEZ-SALGADO, C., LÓPEZ-HERNÁNDEZ, F. J. & LÓPEZ-NOVOA, J. M. (2007) Glomerular nephrotoxicity of aminoglycosides. Toxicology Applied Pharmacology 223, 86-98.
49. MEDLEAU, L., LONG, R. E., BROWN, J. & MILLER, W. H. (1986) Frequency and antimicrobial susceptibility of Staphylococcus species isolated from canine pyodermas. American Journal of Veterinary Research 47, 229-231.
50. MORRIS, D. O., ROOK, K. A., SHOFER, F. S. & RANKIN, S. C. (2006) Screening of Staphylococcus aureus, Staphylococcus intermedius, and Staphylococcus schleiferi isolates obtained from small companion animals for antimicrobial resistance: a retrospective review of 749 isolates (2003-04). Veterinary Dermatology 17, 332-337.
51. MUELLER, R. S. & STEPHAN, B. (2007) Pradofloxacin in the treatment of canine deep pyoderma: a multicentred, blinded, randomized parallel trial. Veterinary Dermatology 18, 144-151.
52. MURAYAMA, N., NAGATA, M., TERADA, Y., SHIBATA, S. & FUKATA, T. (2010) Efficacy of a surgical scrub including 2% chlorhexidine acetate for canine superficial pyoderma. Veterinary Dermatology 21, 586-592.
53. NOLI, C., KOEMAN, J. P. & WILLEMSE, T. (1995) A retrospective evaluation of adverse reactions to trimethoprim-sulfonamide combinations in dogs and cats. Veterinary Quarterly 17, 123-128.
54. NOLI, C. & MORRIS, D. (2011) Letters to the Editor: guidelines on the use of systemic aminoglycosides in veterinary dermatology. Veterinary Dermatology 22, 379-380.
55. NOLI, C. & SCARAMPELLA, F. (1999) Cefadroxil nelle infezioni cutanee del cane. Efficacia della somministrazione per via orale effettuata una volta al giorno. Obiettivi e Documenti Veterinari 12S.
56. NORSTRÖM, M., SUNDE, M., THARALDSEN, H., MØRK, T., BERGSJØ, B. & KRUSE, H. (2009) Antimicrobial resistance in Staphylococcus pseudintermedius in the Norwegian dog population. Microbial Drug Resistance 15, 55-59.
57. PAPICH, M. G. (1988) Therapy of Gram-positive bacterial infections. Veterinary Clinics of North America: Small Animal Practice 18, 1267-1285.
58. PAPICH, M. G., DAVIS, J. L. & FLOERCHINGER, A. M. (2010) Pharmacokinetics, protein binding, and tissue distribution of orally administered cefpodoxime proxetil and cephalexin in dogs. American Journal of Veterinary Research 71, 1484-1491.
59. PARADIS, M., ABBEY, L., BAKER, B., COYNE, M., HANNIGAN, M., JOFFE, D., PUKAY, B., TRETTIEN, A., WAISGLASS, S. & WELLINGTON, J. (2001) Evaluation of the clinical efficacy of marbofloxacin (Zeniquin®) tablets for the treatment of canine pyoderma: an open clinical trial. Veterinary Dermatology 12, 163-169.
60. PARADIS, M., LEMAY, S., SCOTT, D. W., MILLER, W. H., WELLINGTON, J. & PANICH, R. (1990) Efficacy of enrofloxacin in the treatment of canine bacterial pyoderma. Veterinary Dermatology 1, 123-127.
61. PELLERIN, J. L., BOURDEAU, P., SEBBAG, H. & PERSON, J. M. (1998) Epidemiosurveillance of antimicrobial compound resistance of Staphylococcus intermedius clinical isolates from canine pyodermas. Comparative Immunology Microbiology and Infectious Diseases 21, 115-133.
62. PIRIZ, S., VALLE, J., MATEOS, E. M., DE LA FUENTE, R., CID, D., RUIZSANTAQUITERIA, J. A. & VADILLO, S. (1996) In vitro activity of fifteen antimicrobial agents against methicillin-resistant and methicillin-susceptible Staphylococcus intermedius. Journal of Veterinary Pharmacology and Therapeutics 19, 118-123.
63. PRESCOTT, J. F., HANNA, W. J., REID-SMITH, R. & DROST, K. (2002) Antimicrobial drug use and resistance in dogs. Canadian Veterinary Journal 43, 107-116.
64. RESTREPO, C., IHRKE, P. J., WHITE, S. D., SPIEGEL, I. B. & AFFOLTER, V. K. (2010) Evaluation of the clinical efficacy of pradofloxacin tablets for the treatment of canine pyoderma. Journal of the American Animal Hospital Association 46, 301-311.
65. ROTTER, M. L., SIMPSON, R. A. & KOLLER, W. (1998) Surgical hand disinfection with alcohols at various concentrations: parallel experiments using the new proposed European standards method. Infection Control and Hospital Epidemiology 19, 778-781.
66. SAIJONMAA-KOULUMIES, L., PARSONS, E. & LLOYD, D. H. (1998) Elimination of Staphylococcus intermedius in healthy dogs by topical treatment with fusidic acid. Journal of Small Animal Practice 39, 341-347.
67. SARIDOMICHELAKIS, M. N., ATHANASIOU, L. V., SALAME, M., CHATZIS, M. K., KATSOUDAS, V. & PAPPAS, I. S. (2011) Serum pharmacokinetics of clindamycin hydrochloride in normal dogs when administered at two dosage regimens. Veterinary Dermatology 22, 429-435.
68. SCHNEIDER, M., THOMAS, V., BOISRAME, B. & DELEFORGE, J. (1996) Pharmacokinetics of marbofloxacin in dogs after oral and parenteral administration. Journal of Veterinary Pharmacology and Therapeutics 19, 56-61.
69. SCOTT, D. W., MILLER, W. H., Jr, CAYATTE, S. M. & BAGLADI, M. S. (1994) Efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. Canadian Veterinary Journal 35, 617-621.
70. SCOTT, D. W., MILLER, W. H. & GRIFFIN, C. E. (2001). Bacterial skin infections. In Muller and Kirk's Small Animal Dermatology. 6th edn. W. B. Saunders. pp 274-335.
71. SCOTT, D. W., PETERS, J. & MILLER, W. H., Jr (2006) Efficacy of orbifloxacin tablets for the treatment of superficial and deep pyoderma due to Staphylococcus intermedius infection in dogs. Canadian Veterinary Journal 47, 999-1002.
72. SHEPARD, R. M. & FALKNER, F. C. (1990) Pharmacokinetics of azithromycin in rats and dogs. Journal of Antimicrobial Chemotherapy 25, 49-60.
73. SIX, R., CHERNI, J., CHESEBROUGH, R., CLEAVER, D., LINDEMAN, C. J., PAPP, G., SKOGERBOE, T. L., WEIGEL, D. J., BOUCHER, J. F. & STEGEMANN, M. R. (2008) Efficacy and safety of cefovecin in treating bacterial folliculitis, abscesses, or infected wounds in dogs. Journal of the American Veterinary Medical Association 233, 433-439.
74. STEGEMANN, M. R., COATI, N., PASSMORE, C. A. & SHERINGTON, J. (2007) Clinical efficacy and safety of cefovecin in the treatment of canine pyoderma and wound infection. Journal of Small Animal Practice 48, 378-386.
75. SUMMERS, J. F., BRODBELT, D. C., FORSYTHE, P. J., LOEFFLER, A. & HENDRICKS, A. (2012) The effectiveness of systemic antimicrobial treatment in canine superficial and deep pyoderma: a systematic review. Veterinary Dermatology 23, 309-323.
76. TOMA, S., COLOMBO, S., CORNEGLIANI, L., PERSICO, P., GALZERANO, M., GIANINO, M. M. & NOLI, C. (2008) Efficacy and tolerability of once-daily cephalexin in canine superficial pyoderma: an open controlled study. Journal of Small Animal Practice 49, 384-391.
77. TORRES, M. J. & BLANCA, M. (2010) The complex clinical picture of beta-lactam hypersensitivity: penicillins, cephalosporins, monobactams, carbapenems, and clavams. Medical Clinics of North America 94, 805-820.
78. TREPANIER, L. A. (1999) Delayed hypersensitivity reactions to sulphonamides: syndromes, pathogenesis and management. Veterinary Dermatology 20, 241-248.
79. VAN VLAENDEREN, I., NAUTRUP, B. P. & GASPER, S. M. (2011) Estimation of the clinical and economic consequences of non-compliance with antimicrobial treatment of canine skin infections. Preventive Veterinary Medicine 99, 201-210.
80. YOON, J. W., LEE, K. J., LEE, S. Y., CHAE, M. J., PARK, J. K., YOO, J. H. & PARK, H. M. (2010) Antibiotic resistance profiles of Staphylococcus pseudintermedius isolates from canine patients in Korea. Journal of Microbiology Biotechnology 20, 1764-1768.
81. WHO (2009) World Health Organization Guidelines on Hand Hygiene in Health Care. First Global Patient Safety Challenge: Clean Care is Safer Care. World Health Organization.