Evaluation of the clinical efficacy of pradofloxacin tablets for the treatment of canine pyoderma

Journal of the American Animal Hospital Association

Volumn 46, Issue 5, 2010, Pages 301-311

  Restrepo, Christina ^a,b   Ihrke, Peter J ^a   White, Stephen D ^a   Spiegel, Ian B ^a   Affolter, Verena K ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Animal Dermatology Clinic   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA (MICROORGANISMS); CANIS FAMILIARIS;

EID: 77956284616     PISSN: 15473317     EISSN: 15473317     Source Type: Journal    
DOI: 10.5326/0460301     Document Type: Article

References (52)

1. Ihrke P. Bacterial skin disease in the dog: a guide to canine pyoderma. Trenton: Veterinary Learning Systems, 1996.
2. Scott D, Miller W, Griffin C. Muller and Kirk's Small Animal Dermatology. 6th ed. Philadelphia: WB Saunders, 2001.
3. White SD, Ceragioli KL, Stewart LJ, et al. Cutaneous markers of canine hyperadrenocorticism. Compend Contin Educ 1989;11: 446-465.
4. Ihrke PJ. Bacterial infections of the skin. In: Greene CE, ed. Infectious Diseases of the Dog and Cat. Philadelphia: WB Saunders, 1998:541-547.
5. White S. Food allergy in dogs. Compend Contin Educ 1998;20: 261-269.
6. DeBoer DJ, Marsella R. The ACVD task force on canine atopic dermatitis (XII): the relationship of cutaneous infections to the pathogenesis and clinical course of canine atopic dermatitis. Vet Immunol Immunopathol 2001;81:239-249.
7. Gulikers K, Panciera D. Influence of various medications on canine thyroid function. Compend Contin Educ Pract Vet 2002;24:511-523.
8. Barriga OO, al-Khalidi NW, Martin S, et al. Evidence of immunosuppression by Demodex canis. Vet Immunol Immunopathol 1992;32:37-46.
9. Gross TL, Ihrke PJ, Walder EJ, et al. Skin Diseases of the Dog and Cat: Clinical and Histopathologic Diagnosis. 2nd ed. Ames: Blackwell Science Ltd., 2005.
10. Mueller RS, Stephan B. Pradofloxacin in the treatment of canine deep pyoderma: a multicentred, blinded, randomized parallel trial. Vet Dermatol 2007;18:144-151.
11. Petersen AD, Walker RD, Bowman MM, et al. Frequency of isolation and antimicrobial susceptibility patterns of Staphylococcus intermedius and Pseudomonas aeruginosa isolates from canine skin and ear samples over a 6-year period (1992-1997). J Am Anim Hosp Assoc 2002;38:407-413.
12. White SD, Brown AE, Chapman PL, et al. Evaluation of aerobic bacteriologic culture of epidermal collarette specimens in dogs with superficial pyoderma. J Am Vet Med Assoc 2005;226:904-908.
13. Hillier A, Alcorn JR, Cole LK, et al. Pyoderma caused by pseudomonas aeruginosa infection in dogs: 20 cases. Vet Dermatol 2006;17:432-439.
14. Jang SS, Breher JE, Dabaco LA, et al. Organisms isolated from dogs and cats with anaerobic infections and susceptibility to selected antimicrobial agents. J Am Vet Med Assoc 1997;210:1610-1614.
15. White SD. Systemic treatment of bacterial skin infections of dogs and cats. Vet Dermatol 1996;7:133-144.
16. Carlotti DN. New trends in systemic antibiotic therapy of bacterial skin disease in dogs. Compend Contin Educ 1996;18:40-47.
17. Dowling PM. Antimicrobial therapy of skin and ear infections. Can Vet J 1996;37:695-699.
18. Jazic E, Coyner KS, Loeffler DG, et al. An evaluation of the clinical, cytological, infectious and histopathological features of feline acne. Vet Dermatol 2006;17:134-140.
19. Patel A, Lloyd DH, Lamport AI. Antimicrobial resistance of feline staphylococci in south-eastern England. Vet Dermatol 1999;10: 257-261.
20. Morris DO, Rook KA, Shofer FS, et al. Screening of staphylococcus aureus, staphylococcus intermedius, and staphylococcus schleiferi isolates obtained from small companion animals for antimicrobial resistance: a retrospective review of 749 isolates (2003-04). Vet Dermatol 2006;17:332-337.
21. Ganiere JP, Medaille C, Mangion C. Antimicrobial drug susceptibility of staphylococcus intermedius clinical isolates from canine pyoderma. J Vet Med B Infect Dis Vet Public Health 2005;52:25-31.
22. Abraham J, Morris D, Griffeth G, et al. Screening of healthy cats and cats with inflammatory skin disease for colonization of the skin by methicillin-resistant coagulase-positive staphylococci and staphylococcus schleiferi subspecies schleiferi. In: 22nd Proceed, N Am Vet Dermatol Forum, Kauai, HI 2007:173.
23. Silley P, Stephan B, Greife HA, et al. Comparative activity of pradofloxacin against anaerobic bacteria isolated from dogs and cats. J Antimicrob Chemother 2007;60:999-1003.
24. Pridmore A, Stephan B, Greife HA, et al. In vitro activity of pradofloxacin against clinical isolates from European field studies. In: 105th Ann General Meeting Am Soc Microbiol, Atlanta, GA 2005.
25. Mueller RS, Stephan B. Pradofloxacin in the treatment of canine deep pyoderma: a multicentred, blinded, randomized parallel trial. Vet Dermatol 2007;18:144-151.
26. Fraatz K, Krebber R, Edingloh M, et al. Communications: oral bioavailability of pradofloxacin tablets and renal drug excretion in dogs. J Vet Pharmacol Therap 2003;26:88-89.
27. Fraatz K, Heinen K, Krebber R, et al. Communications: skin concentrations and serum pharmacokinetics of pradofloxacin in dogs after multiple oral administrations at four different dosages. J Vet Pharmacol Therap 2003;26:89.
28. Bregante MA, De Jong A, Calvo A, et al. Communications: protein binding of pradofloxacin, a novel 8-cyanofluoroquinolone, in dog and cat plasma. J Vet Pharmacol Therap 2003;26:87-88.
29. Wright DH, Brown GH, Peterson ML, et al. Application of fluoroquinolone pharmacodynamics. J Antimicrob Chemother 2000;46:669-683.
30. Litster A, Moss S, Honnery M, et al. Clinical efficacy and palatability of pradofloxacin 2.5% oral suspension for the treatment of bacterial lower urinary tract infections in cats. J Vet Intern Med 2007;21:990-995.
31. Paradis M, Abbey L, Baker B, et al. Evaluation of the clinical efficacy of marbofloxacin (Zeniquin) tablets for the treatment of canine pyoderma: an open clinical trial. Vet Dermatol 2001;12:163-169.
32. Ihrke PJ, Papich MG, DeManuelle TC. The use of fluoroquinolones in veterinary dermatology. Vet Dermatol 1999;10:193-204.
33. Spindel ME, Lappin MR, Bachman D, et al. Pradofloxacin for the treatment of suspected feline bacterial rhinitis. J Vet Intern Med 2007;21:627-628.
34. Gough A, Kasali O, Sigler R, et al. Quinolone arthropathy-acute toxicity to immature articular cartilage. Toxicol Pathol 1992;20: 436-449.
35. Willemse A. Atopic skin disease: a review and a re-consideration of diagnostic criteria. J Small Anim Pract 1986;27:771-778.
36. Prelaud P, Guagere E, Alhaidari Z. Reevaluation of diagnostic criteria of canine atopic dermatitis. Rev Med Vet 1998;149:1057-1064.
37. Carlotti DN, Jacobs DE. Therapy, control and prevention of flea allergy dermatitis in dogs and cats. Vet Dermatol 2000;11:83-98.
38. Mueller RS. Treatment protocols for demodicosis: an evidence-based review. Vet Dermatol 2004;15:75-89.
39. Shanks DJ, McTier TL, Behan S, et al. The efficacy of selamectin in the treatment of naturally acquired infestations of Sarcoptes scabiei on dogs. Vet Parasitol 2000;91:269-281.
40. Finora K, Greco D. Hypothyroidism and myxedema coma. Compend Contin Educ 2007;29:19-32.
41. Ferguson D. Thyroid hormone replacement therapy. In: Kirk R, ed. Current Veterinary Therapy IX Small Animal Practice. Philadelphia: WB Saunders, 1986:1018-1025.
42. Ashcroft G, Horan M, Ferguson M. Aging alters the inflammatory and endothelial cell adhesion molecule profiles during human cutaneous wound healing. Lab Invest 1998;78:47.
43. Desai H. Aging and wounds. Healing in old age. J Wound Care 1997;6:237.
44. Gerstein A, Phillips T, Rogers G, et al. Wound healing and aging. Derm Clin 1993;11:749.
45. Van de Kerkhof P, VanBergen B, Spruijt K, et al. Age-related changes in wound healing. Clin Exp Derm 1994;19:36.
46. Yaar M. Molecular mechanisms of skin aging. Adv Derm 1997;10:64.
47. Toman M, Svoboda M, Rybnicek J, et al. Immunosuppression in dogs with pyoderma and/or demodicosis. Vet Med (Praha) 1997;42:299-306.
48. Scott D, Miller W, Griffin C. Muller & Kirk's Small Animal Dermatology. 6th ed. Philadelphia: WB Saunders, 2001:288-289.
49. Ihrke P. The management of canine pyoderma. In: Kirk R, ed. Current Veterinary Therapy VIII. Philadelphia: WB Saunders, 1983:505-517.
50. Ihrke P, Halliwell REW, Deubler M. Canine pyoderma. In: Kirk R, ed. Current Veterinary Therapy VI. Philadelphia: WB Saunders, 1976:513-519.
51. Tarpataki N. Recent developments in canine atopic dermatitis: a review. Acta Vet Hung 2006;54:473-484.
52. McEwan NA, Mellor D, Kalna G. Adherence by staphylococcus intermedius to canine corneocytes: a preliminary study comparing noninflamed and inflamed atopic canine skin. Vet Dermatol 2006;17:151-154.