The comparative plasma pharmacokinetics of intravenous cefpodoxime sodium and oral cefpodoxime proxetil in beagle dogs

Journal of Veterinary Pharmacology and Therapeutics

Volumn 30, Issue 4, 2007, Pages 320-326

  Brown, S A ^a   Boucher, J F ^a   Hubbard, V L ^a   Prough, M J ^a   Flook, T F ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CEFPODOXIME; CEFPODOXIME PROXETIL;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DOG; DRUG BIOAVAILABILITY; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG HALF LIFE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE; SKIN INFECTION;

ADMINISTRATION, ORAL; ANIMALS; ANTI-BACTERIAL AGENTS; AREA UNDER CURVE; CEFTIZOXIME; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOGS; FEMALE; INJECTIONS, INTRAVENOUS; MALE;

CANIS FAMILIARIS;

EID: 34347407582     PISSN: 01407783     EISSN: 13652885     Source Type: Journal    
DOI: 10.1111/j.1365-2885.2007.00873.x     Document Type: Article

References (6)

1. Anonymous (2003) Vantin (cefpodoxime proxetil) Product Label. U.S. Patent No. 4,668,783. Licensed from Sankyo Company, Ltd., Japan. Made by: Pharmacia N.V./S.A., Puurs, Belgium. For: Pharmacia & Upjohn.
2. Anonymous (2004) Simplicef (cefpodoxime proxetil) Freedom of Information Summary, NADA 141-232.
3. Borin, M.T. (1991) A review of the pharmacokinetics of cefpodoxime proxetil. Drugs, 42, 13 21.
4. Borin, M.T., Hughes, G.S., Spillers, C.R. Patel, R.K. (1990) Pharmacokinetics of cefpodoxime in plasma and skin blister fluid following oral dosing of cefpodoxime proxetil. Antimicrobial Agents and Chemotherapy, 34, 1094 1099.
5. Liu, P., Müller, M., Grant, M., Webb, A.I., Obermann, B. Derendorf, H. (2002). Interstitial tissue concentrations of cefpodoxime. Journal of Antimicrobial Chemotherapy, 50, 19 22.
6. O'Neill, P., Nye, K., Douce, G., Andrews, J. Wise, R. (1990) Pharmacokinetics and inflammatory fluid penetration of cefpodoxime proxetil in volunteers. Antimicrobial Agents and Chemotherapy, 34, 232 234.