Subendocardial increase in reactive oxygen species production affects regional contractile function in ischemic heart failure

Antioxidants and Redox Signaling

Volumn 18, Issue 9, 2013, Pages 1009-1020

  Andre, Lucas ^a   Fauconnier, Jeremy ^a   Reboul, Cyril ^b   Feillet Coudray, Christine ^c   Meschin, Pierre ^a   Farah, Charlotte ^b   Fouret, Gilles ^c   Richard, Sylvain ^a   Lacampagne, Alain ^a   Cazorla, Olivier ^a  

^a INSERM   (France)

^b UNIVERSITY OF AVIGNON   (France)

^c University of Montpellier   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; CATALASE; CITRATE SYNTHASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TROPONIN I;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ELECTRON TRANSPORT; EPICARDIUM; HEART CONTRACTION; HEART FAILURE; HEART INFARCTION; HEART MUSCLE CELL; IN VIVO STUDY; MITOCHONDRIAL RESPIRATION; MYOFILAMENT; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ACETYLCYSTEINE; ANIMALS; ANTIOXIDANTS; CALCIUM; CATALASE; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNITS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; HEART FAILURE; LIPID PEROXIDATION; MALE; MITOCHONDRIA, HEART; MYOCARDIAL CONTRACTION; MYOCARDIAL ISCHEMIA; MYOCYTES, CARDIAC; MYOFIBRILS; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RANDOM ALLOCATION; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RECOMBINANT PROTEINS; SUPEROXIDE DISMUTASE;

EID: 84874068388     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2012.4534     Document Type: Article

References (46)

1. Adamy C, Mulder P, Khouzami L, Andrieu-abadie N, Defer N, Candiani G, Pavoine C, Caramelle P, Souktani R, Le Corvoisier P, Perier M, Kirsch M, Damy T, Berdeaux A, Levade T, Thuillez C, Hittinger L, and Pecker F. Neutral sphingomyelinase inhibition participates to the benefits of N-acetylcysteine treatment in post-myocardial infarction failing heart rats. J Mol Cell Cardiol 43: 344-353, 2007.
2. Andre L, Gouzi F, Thireau J, Meyer G, Boissiere J, Delage M, Abdellaoui A, Feillet-Coudray C, Fouret G, Cristol JP, La-campagne A, Obert P, Reboul C, Fauconnier J, Hayot M, Richard S, and Cazorla O. Carbon monoxide exposure enhances arrhythmia after cardiac stress: involvement of oxi-dative stress. Basic Res Cardiol 106: 1235-1246, 2011.
3. Anyukhovsky EP, Sosunov EA, and Rosen MR. Regional differences in electrophysiological properties of epicardium, midmyocardium, and endocardium. In vitro and in vivo correlations. Circulation 94: 1981-1988, 1996.
4. 2 alters rat cardiac sarcomere function and protein phosphorylation through redox signaling. Am J Physiol Heart Circ Physiol 299: H723-H730, 2010.
5. Avner BS, Shioura KM, Scruggs SB, Grachoff M, Geenen DL, Helseth DL, Jr., Farjah M, Goldspink PH, and John Solaro R. Myocardial infarction in mice alters sarcomeric function via post-translational protein modification. Mol Cell Biochem 363: 203-215, 2012.
6. Belin RJ, Sumandea MP, Allen EJ, Schoenfelt K, Wang H, Solaro RJ, and de Tombe PP. Augmented protein kinase C-alpha-induced myofilament protein phosphorylation contributes to myofilament dysfunction in experimental congestive heart failure. Circ Res 101: 195-204, 2007.
7. Beyar R and Sideman S. Left ventricular mechanics related to the local distribution of oxygen demand throughout the wall. Circ Res 58: 664-677, 1986.
8. Bin JP, Le E, Pelberg RA, Coggins MP, Wei K, and Kaul S. Mechanism of inducible regional dysfunction during di-pyridamole stress. Circulation 106: 112-117, 2002.
9. Bogaert J and Rademakers FE. Regional nonuniformity of normal adult human left ventricle. Am J Physiol Heart Circ Physiol 280: H610-H620, 2001.
10. Bourraindeloup M, Adamy C, Candiani G, Cailleret M, Bourin MC, Badoual T, Su JB, Adubeiro S, Roudot-Thoraval F, Dubois-Rande JL, Hittinger L, and Pecker F. N-acetylcysteine treatment normalizes serum tumor necrosis factor-alpha level and hinders the progression of cardiac injury in hypertensive rats. Circulation 110: 2003-2009, 2004.
11. Brennan JP, Bardswell SC, Burgoyne JR, Fuller W, Schroder E, Wait R, Begum S, Kentish JC, and Eaton P. Oxidant-induced activation of type I protein kinase A is mediated by RI subunit interprotein disulfide bond formation. J Biol Chem 281: 21827-21836, 2006.
12. Canton M, Menazza S, Sheeran FL, Polverino de Laureto P, Di Lisa F, and Pepe S. Oxidation of myofibrillar proteins in human heart failure. J Am Coll Cardiol 57: 300-309, 2011.
13. Cazorla O, Ait Mou Y, Goret L, Vassort G, Dauzat M, La-campagne A, Tanguy S, and Obert P. Effects of high-altitude exercise training on contractile function of rat skinned car-diomyocyte. Cardiovasc Res 71: 652-660, 2006.
14. Cazorla O and Lacampagne A. Regional variation in myo-filament length-dependent activation. Pflugers Arch 462: 15-28, 2011.
15. Cazorla O, Szilagyi S, Le Guennec JY, Vassort G, and La-campagne A. Transmural stretch-dependent regulation of contractile properties in rat heart and its alteration after myocardial infarction. FASEB J 19: 88-90, 2005.
16. Derumeaux G, Mulder P, Richard V, Chagraoui A, Nafeh C, Bauer F, Henry JP, and Thuillez C. Tissue Doppler imaging differentiates physiological from pathological pressure-overload left ventricular hypertrophy in rats. Circulation 105: 1602-1608, 2002.
17. Derumeaux G, Ovize M, Loufoua J, Pontier G, Andre-Fouet X, and Cribier A. Assessment of nonuniformity of trans-mural myocardial velocities by color-coded tissue Doppler imaging: characterization of normal, ischemic, and stunned myocardium. Circulation 101: 1390-1395, 2000.
18. Duncker DJ, Boontje NM, Merkus D, Versteilen A, Krysiak J, Mearini G, El-Armouche A, de Beer VJ, Lamers JM, Carrier L, Walker LA, Linke WA, Stienen GJ, and van der Velden J. Prevention of myofilament dysfunction by beta-blocker therapy in postinfarct remodeling. Circ Heart Fail 2: 233-242, 2009.
19. Feigl EO. Coronary physiology. Physiol Rev 63: 1-205, 1983.
20. Fitzsimons DP, Patel JR, and Moss RL. Role of myosin heavy chain composition in kinetics of force development and relaxation in rat myocardium. J Physiol 513: 171-183, 1998.
21. Furukawa T, Myerburg RJ, Furukawa N, Bassett AL, and Kimura S. Differences in transient outward currents of feline endocardial and epicardial myocytes. Circ Res 67: 1287-1291, 1990.
22. Giordano FJ. Oxygen, oxidative stress, hypoxia, and heart failure. J Clin Invest 115: 500-508, 2005.
23. Hamilton KL, Staib JL, Phillips T, Hess A, Lennon SL, and Powers SK. Exercise, antioxidants, and HSP72: protection against myocardial ischemia/reperfusion. Free Radic Biol Med 34: 800-809, 2003.
24. Hertelendi Z, Toth A, Borbely A, Galajda Z, van der Velden J, Stienen GJ, Edes I, and Papp Z. Oxidation of myofilament protein sulfhydryl groups reduces the contractile force and its Ca2 + sensitivity in human cardiomyocytes. Antioxid Redox Signal 10: 1175-1184, 2008.
25. Hittinger L, Shannon RP, Bishop SP, Gelpi RJ, and Vatner SF. Subendomyocardial exhaustion of blood flow reserve and increased fibrosis in conscious dogs with heart failure. Circ Res 65: 971-980, 1989.
26. Ide T, Tsutsui H, Kinugawa S, Utsumi H, Kang D, Hattori N, Uchida K, Arimura K, Egashira K, and Takeshita A. Mi-tochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium. Circ Res 85: 357-363, 1999.
27. Janssen PM and de Tombe PP. Protein kinase A does not alter unloaded velocity of sarcomere shortening in skinned rat cardiac trabeculae. Am J Physiol 273: H2415-H2422, 1997.
28. Kainulainen H, Komulainen J, Leinonen A, Rusko H, and Vihko V. Regional differences of substrate oxidation capacity in rat hearts: effects of extra load and endurance training. Basic Res Cardiol 85: 630-639, 1990.
29. Kaumann A, Bartel S, Molenaar P, Sanders L, Burrell K, Vetter D, Hempel P, Karczewski P, and Krause EG. Activation of beta2-adrenergic receptors hastens relaxation and mediates phosphorylation of phospholamban, troponin I, and C-protein in ventricular myocardium from patients with terminal heart failure. Circulation 99: 65-72, 1999.
30. Kelley DE, He J, Menshikova EV, and Ritov VB. Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 51: 2944-2950, 2002.
31. Lee T-M, Lai P-Y, and Chang N-C. Effect of N-acetylcysteine on sympathetic hyperinnervation in post-infarcted rat hearts. Cardiovasc Res 85: 137-146, 2010.
32. Leosco D, Rengo G, Iaccarino G, Golino L, Marchese M, For-tunato F, Zincarelli C, Sanzari E, Ciccarelli M, Galasso G, Al-tobelli GG, Conti V, Matrone G, Cimini V, Ferrara N, Filippelli A, Koch WJ, and Rengo F. Exercise promotes angiogenesis and improves beta-adrenergic receptor signalling in the post-ischaemic failing rat heart. Cardiovasc Res 78: 385-394, 2008.
33. Locher MR, Razumova MV, Stelzer JE, Norman HS, Patel JR, and Moss RL. Determination of rate constants for turnover of myosin isoforms in rat myocardium: implications for in vivo contractile kinetics. Am J Physiol Heart Circ Physiol 297: H247-H256, 2009.
34. Mou YA, Reboul C, Andre L, Lacampagne A, and Cazorla O. Late exercise training improves non-uniformity of trans-mural myocardial function in rats with ischaemic heart failure. Cardiovasc Res 81: 555-564, 2009.
35. Neubauer S. The failing heart-an engine out of fuel. N Engl J Med 356: 1140-1151, 2007.
36. Path G, Robitaille PM, Merkle H, Tristani M, Zhang J, Gar-wood M, From AH, Bache RJ, and Ugurbil K. Correlation between transmural high energy phosphate levels and myocardial blood flow in the presence of graded coronary stenosis. Circ Res 67: 660-673, 1990.
37. Sam F, Kerstetter DL, Pimental DR, Mulukutla S, Tabaee A, Bristow MR, Colucci WS, and Sawyer DB. Increased reactive oxygen species production and functional alterations in an-tioxidant enzymes in human failing myocardium. J Cardiac Fail 11: 473-480, 2005.
38. Stanley WC, Recchia FA, and Lopaschuk GD. Myocardial substrate metabolism in the normal and failing heart. Physiol Rev 85: 1093-1129, 2005.
39. Stolen KQ, Kemppainen J, Ukkonen H, Kalliokoski KK, Luotolahti M, Lehikoinen P, Hamalainen H, Salo T, Air-aksinen KE, Nuutila P, and Knuuti J. Exercise training improves biventricular oxidative metabolism and left ventricular efficiency in patients with dilated cardiomyopa-thy. J Am Coll Cardiol 41: 460-467, 2003.
40. Sumandea MP and Steinberg SF. Redox signaling and cardiac sarcomeres. J Biol Chem 286: 9921-9927, 2011.
41. Takimoto E and Kass DA. Role of oxidative stress in cardiac hypertrophy and remodeling. Hypertension 49: 241-248, 2007.
42. Tsutsui H, Kinugawa S, and Matsushima S. Oxidative stress and heart failure. Am J Physiol Heart Circ Physiol 301: H2181-H2190, 2011.
43. van der Velden J, Merkus D, Klarenbeek BR, James AT, Boontje NM, Dekkers DH, Stienen GJ, Lamers JM, and Duncker DJ. Alterations in myofilament function contribute to left ventricular dysfunction in pigs early after myocardial infarction. Circ Res 95: e85-e95, 2004.
44. Wang H, Hiatt WR, Barstow TJ, and Brass EP. Relationships between muscle mitochondrial DNA content, mitochondrial enzyme activity and oxidative capacity in man: alterations with disease. Eur J Appl Physiol Occup Physiol 80: 22-27, 1999.
45. Whitty AJ, Dimino MJ, Elfont EA, Hughes GW, and Repeck MW. Transmural mitochondrial differences in myocardium. Recent Adv Stud Cardiac Struct Metab 11: 349-354, 1976.
46. Zima AV and Blatter LA. Redox regulation of cardiac calcium channels and transporters. Cardiovasc Res 71: 310-321, 2006.