Proton sensors in the pore domain of the cardiac voltage-gated sodium channel

Journal of Biological Chemistry

Volumn 288, Issue 7, 2013, Pages 4782-4791

  Jones, David K ^a   Peters, Colin H ^a   Allard, Charlene R ^a   Claydon, Tom W ^a   Ruben, Peter C ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIAC ARRHYTHMIA; PATHOPHYSIOLOGY; PROTON SENSORS; SODIUM CHANNEL; SODIUM CHANNEL FUNCTIONS;

AMINO ACIDS; PROTONS;

HEART;

CYSTEINE; HISTIDINE; PROTON; SODIUM CHANNEL NAV1.5;

ACIDOSIS; AMINO ACID ANALYSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING KINETICS; CELL PH; CHANNEL GATING; CONTROLLED STUDY; FEMALE; HUMAN; ION CONDUCTANCE; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; P LOOP; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN STRUCTURE; PROTON BLOCK; PROTON TRANSPORT; SEQUENCE ALIGNMENT; STEADY STATE SLOW INACTIVATION; USE DEPENDENT INACTIVATION; WILD TYPE; XENOPUS;

ACIDOSIS; AMINO ACID SEQUENCE; ANIMALS; ARRHYTHMIAS, CARDIAC; ELECTROPHYSIOLOGY; FEMALE; HUMANS; ISCHEMIA; MOLECULAR SEQUENCE DATA; MYOCARDIAL ISCHEMIA; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; OOCYTES; PATCH-CLAMP TECHNIQUES; PROTONS; SEQUENCE HOMOLOGY, AMINO ACID; SODIUM CHANNELS; TIME FACTORS; VOLTAGE-GATED SODIUM CHANNELS; XENOPUS;

EID: 84874068206     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.434266     Document Type: Article

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