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Volumn 121, Issue 7, 2013, Pages 1068-1069

Inhibiting the hepcidin inhibitor for treatment of iron overload

Author keywords

[No Author keywords available]

Indexed keywords

HEPCIDIN; MEMBRANE PROTEIN; NANOPARTICLE; TMPRSS6 PROTEIN; UNCLASSIFIED DRUG;

EID: 84874067350     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-12-472597     Document Type: Note
Times cited : (12)

References (10)
  • 1
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    • An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe-/-mice and ameliorates anemia and iron overload in murine |3-thalassemia intermedia
    • Schmidt PJ, Toudjarska I, Sendamarai AK, et al. An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe-/-mice and ameliorates anemia and iron overload in murine |3-thalassemia intermedia. Blood. 2013; 121(7):1200-1208.
    • (2013) Blood. , vol.121 , Issue.7 , pp. 1200-1208
    • Schmidt, P.J.1    Toudjarska, I.2    Sendamarai, A.K.3
  • 2
    • 77954249308 scopus 로고    scopus 로고
    • Two to tango: Regulation of Mammalian iron metabolism
    • Hentze MW, Muckenthaler MU, Galy B, Camaschella C. Two to tango: regulation of Mammalian iron metabolism. Cell. 2010;142(1):24-38.
    • (2010) Cell , vol.142 , Issue.1 , pp. 24-38
    • Hentze, M.W.1    Muckenthaler, M.U.2    Galy, B.3    Camaschella, C.4
  • 5
    • 56449096622 scopus 로고    scopus 로고
    • The serine protease matriptase-2 (TM-PRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin
    • Silvestri L, Pagani A, Nai A, De Domenico I, Kaplan J, Camaschella C. The serine protease matriptase-2 (TM-PRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin. Cell Metab. 2008;8(6):502-511.
    • (2008) Cell Metab , vol.8 , Issue.6 , pp. 502-511
    • Silvestri, L.1    Pagani, A.2    Nai, A.3    De Domenico, I.4    Kaplan, J.5    Camaschella, C.6
  • 6
    • 84868545645 scopus 로고    scopus 로고
    • Minihepcid-ins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis
    • Ramos E, Ruchala P, Goodnough JB, et al. Minihepcid-ins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis. Blood. 2012;120(18): 3829-3836.
    • (2012) Blood , vol.120 , Issue.18 , pp. 3829-3836
    • Ramos, E.1    Ruchala, P.2    Goodnough, J.B.3
  • 7
    • 79955956398 scopus 로고    scopus 로고
    • Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice
    • Finberg KE, Whittlesey RL, Andrews NC. Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice. Blood. 2011;117(17):4590-4599.
    • (2011) Blood , vol.117 , Issue.17 , pp. 4590-4599
    • Finberg, K.E.1    Whittlesey, R.L.2    Andrews, N.C.3
  • 8
    • 84861525631 scopus 로고    scopus 로고
    • Deletion of TMPRSS6 attenuates the phenotype in a mouse model of thalassemia
    • Nai A, Pagani A, Mandelli G, et al. Deletion of TMPRSS6 attenuates the phenotype in a mouse model of thalassemia. Blood. 2012;119(21):5021-5029.
    • (2012) Blood , vol.119 , Issue.21 , pp. 5021-5029
    • Nai, A.1    Pagani, A.2    Mandelli, G.3
  • 9
    • 76349118307 scopus 로고    scopus 로고
    • Transferrin therapy ameliorates disease inbeta-thalassemic mice
    • Li H, Rybicki AC, Suzuka SM, et al. Transferrin therapy ameliorates disease inbeta-thalassemic mice. Nat Med. 2010;16(2):177-182.
    • (2010) Nat Med , vol.16 , Issue.2 , pp. 177-182
    • Li, H.1    Rybicki, A.C.2    Suzuka, S.M.3
  • 10
    • 78649813036 scopus 로고    scopus 로고
    • Hepcidin as a therapeutic tool to limit iron overload and improve anemia inP-thalassemicmice
    • Gardenghi S, Ramos P, Marongiu MF, et al. Hepcidin as a therapeutic tool to limit iron overload and improve anemia inP-thalassemicmice. JClin Invest. 2010;120(12):4466-4477.
    • (2010) JClin Invest , vol.120 , Issue.12 , pp. 4466-4477
    • Gardenghi, S.1    Ramos, P.2    Marongiu, M.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.