Placental transfer of maraviroc in an ex vivo human cotyledon perfusion model and influence of ABC transporter expression

Antimicrobial Agents and Chemotherapy

Volumn 57, Issue 3, 2013, Pages 1415-1420

  Vinot, C ^a,b   Gavard, L ^c   Treluyer J M ^a,b,d   Manceau, S ^a,b   Courbon, E ^a   Scherrmann, J M ^e   Decleves X ^e   Duro, D ^c   Peytavin, G ^a   Mandelbrot, L ^c   Giraud, C ^a,b,d  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b Assistance Publique Hôpitaux de Paris ^*  (France)

^c HÔPITAL LOUIS MOURIER   (France)

^d HÔTEL DIEU   (France)

^e INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; BREAST CANCER RESISTANCE PROTEIN; MARAVIROC; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; MULTIDRUG RESISTANCE PROTEIN 5; MULTIDRUG RESISTANCE PROTEIN 6; PHENAZONE;

ARTICLE; CLINICAL ARTICLE; CONCENTRATION (PARAMETERS); COTYLEDON; EX VIVO STUDY; FEMALE; GENE EXPRESSION; GOLD STANDARD; HUMAN; HUMAN TISSUE; IN VIVO STUDY; MATERNAL BLOOD; NUCLEOTIDE SEQUENCE; PLACENTA PERFUSION; PLACENTAL TRANSFER; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEADY STATE; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; UMBILICAL CORD BLOOD; WESTERN BLOTTING;

ATP-BINDING CASSETTE TRANSPORTERS; CHROMATOGRAPHY, LIQUID; CYCLOHEXANES; DIFFUSION CHAMBERS, CULTURE; FEMALE; FETUS; GENE EXPRESSION; HIV FUSION INHIBITORS; HUMANS; KINETICS; MATERNAL-FETAL EXCHANGE; MODELS, BIOLOGICAL; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; ORGAN CULTURE TECHNIQUES; P-GLYCOPROTEIN; PERFUSION; PLACENTA; PREGNANCY; TANDEM MASS SPECTROMETRY; TRIAZOLES;

EID: 84874051558     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01821-12     Document Type: Article

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