The Pancreas Is Altered by In Utero Androgen Exposure: Implications for Clinical Conditions Such as Polycystic Ovary Syndrome (PCOS)

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Rae, Mick ^a   Grace, Cathal ^a   Hogg, Kirsten ^b   Wilson, Lisa Marie ^a   McHaffie, Sophie L ^b   Ramaswamy, Seshadri ^a   MacCallum, Janis ^a   Connolly, Fiona ^b   McNeilly, Alan S ^b   Duncan, Colin ^b  

^a EDINBURGH NAPIER UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DIETHYLSTILBESTROL; ESTRADIOL; INSULIN; PLACEBO; TESTOSTERONE; TESTOSTERONE PROPIONATE;

ANDROGEN THERAPY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MATURATION; CONTROLLED STUDY; DEVELOPMENTAL GENE; ESTRADIOL BLOOD LEVEL; ESTROGEN ACTIVITY; EWE; FEMALE; FETUS; FETUS BLOOD SAMPLING; FUNCTIONAL MORPHOLOGY; GENE FUNCTION; GENE IDENTIFICATION; GENE OVEREXPRESSION; GESTATIONAL AGE; HORMONE DETERMINATION; IGF1R GENE; IN VITRO STUDY; INS GENE; INSR GENE; INSULIN RELEASE; INSULIN RESPONSE; MALE; NONHUMAN; OVARY POLYCYSTIC DISEASE; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PDX1 GENE; PHENOTYPE; PRENATAL DRUG EXPOSURE; PROGENY; QUANTITATIVE STUDY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEX DIFFERENCE; SIGNAL TRANSDUCTION; TESTOSTERONE BLOOD LEVEL; UPREGULATION; WESTERN BLOTTING;

ANDROGENS; ANIMALS; ESTRADIOL; ESTROGENS; FEMALE; FETUS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INSULIN; INSULIN-SECRETING CELLS; MALE; MATERNAL EXPOSURE; PANCREAS; POLYCYSTIC OVARY SYNDROME; PREGNANCY; SHEEP; SIGNAL TRANSDUCTION; TESTOSTERONE PROPIONATE;

EID: 84874048533     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056263     Document Type: Article

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