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Volumn 298, Issue 2, 2010, Pages

Excess exposure to insulin may be the primary cause of insulin resistance

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; GLUCOSE; INSULIN; LIPID; PROTEIN KINASE B;

EID: 74949124966     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00677.2009     Document Type: Letter
Times cited : (17)

References (9)
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    • Cook, D.L.1    Mills, L.M.2    Green, D.M.3
  • 2
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    • The effect of alloxan diabetes on experimental cholesterol atherosclerosis in the rabbit. IV. The effect of insulin therapy on the inhibition of atherosclerosis in the alloxan-diabetic rabbit
    • Duff GL, Brechin DJ, Finkelstein WE. The effect of alloxan diabetes on experimental cholesterol atherosclerosis in the rabbit. IV. The effect of insulin therapy on the inhibition of atherosclerosis in the alloxan-diabetic rabbit. J Exp Med 100: 371-380, 1954.
    • (1954) J Exp Med , vol.100 , pp. 371-380
    • Duff, G.L.1    Brechin, D.J.2    Finkelstein, W.E.3
  • 3
    • 84958112553 scopus 로고
    • The effect of alloxan diabetes on experimental cholesterol atherosclerosis in the rabbit
    • Duff GL, McMillan GC. The effect of alloxan diabetes on experimental cholesterol atherosclerosis in the rabbit. J Exp Med 89: 611-630, 1949.
    • (1949) J Exp Med , vol.89 , pp. 611-630
    • Duff, G.L.1    McMillan, G.C.2
  • 4
    • 0037836916 scopus 로고
    • The effect of alloxan diabetes on experimental cholesterol atherosclerosis in the rabbit. III. The mechanism of the inhibition of experimental cholesterol atherosclerosis in alloxan-diabetic rabbits
    • Duff GL, Payne TP. The effect of alloxan diabetes on experimental cholesterol atherosclerosis in the rabbit. III. The mechanism of the inhibition of experimental cholesterol atherosclerosis in alloxan-diabetic rabbits. J Exp Med 92: 299-317, 1950.
    • (1950) J Exp Med , vol.92 , pp. 299-317
    • Duff, G.L.1    Payne, T.P.2
  • 5
    • 70349619811 scopus 로고    scopus 로고
    • Increased basal level of Akt-dependent insulin signaling may be responsible for the development of insulin resistance
    • Liu H, Hong T, Wen GB, Han J, Zhuo D, Liu Z, Cao W. Increased basal level of Akt-dependent insulin signaling may be responsible for the development of insulin resistance. Am J Physiol Endocrinol Metab 297: E898-E906, 2009.
    • (2009) Am J Physiol Endocrinol Metab , vol.297
    • Liu, H.1    Hong, T.2    Wen, G.B.3    Han, J.4    Zhuo, D.5    Liu, Z.6    Cao, W.7
  • 6
    • 70350439438 scopus 로고    scopus 로고
    • Insulin is a stronger inducer of insulin resistance than hyperglycemia in mice with type 1 diabetes mellitus (T1DM)
    • Liu HY, Cao SY, Hong T, Han J, Liu Z, Cao W. Insulin is a stronger inducer of insulin resistance than hyperglycemia in mice with type 1 diabetes mellitus (T1DM). J Biol Chem 284: 27090-27100, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 27090-27100
    • Liu, H.Y.1    Cao, S.Y.2    Hong, T.3    Han, J.4    Liu, Z.5    Cao, W.6
  • 7
    • 71449091240 scopus 로고    scopus 로고
    • Hepatic autophagy is suppressed in the presence of insulin resistance and hyperinsulinemia: Inhibition of FoxO1-dependent expression of key autophagy genes by insulin
    • Liu HY, Han J, Cao YS, Hong T, Zhuo D, Shi J, Liu Z, Cao W. Hepatic autophagy is suppressed in the presence of insulin resistance and hyperinsulinemia: inhibition of FoxO1-dependent expression of key autophagy genes by insulin. J Biol Chem 284: 31484-31492, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 31484-31492
    • Liu, H.Y.1    Han, J.2    Cao, Y.S.3    Hong, T.4    Zhuo, D.5    Shi, J.6    Liu, Z.7    Cao, W.8
  • 8
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    • Prolonged exposure to insulin suppresses mitochondrial production in primary hepatocytes
    • Liu HY, Yehuda-Shnaidman E, Hong T, Han J, Pi J, Liu Z, Cao W. Prolonged exposure to insulin suppresses mitochondrial production in primary hepatocytes. J Biol Chem 284: 14087-14095, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 14087-14095
    • Liu, H.Y.1    Yehuda-Shnaidman, E.2    Hong, T.3    Han, J.4    Pi, J.5    Liu, Z.6    Cao, W.7
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    • Effect of insulin in the induction and regression of atherosclerosis in the chick
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.