No cross-resistance after sequential use of romiplostim and eltrombopag in chronic immune thrombocytopenic purpura

Blood

Volumn 121, Issue 7, 2013, Pages 1240-1242

  D'Arena, Giovanni ^a   Guariglia, Roberto ^a   Mansueto, Giovanna ^a   Martorelli, Maria Carmen ^a   Pietrantuono, Giuseppe ^a   Villani, Oreste ^a   Lerose, Rosa ^a   Musto, Pellegrino ^a  

^a REFERRAL CANCER CENTER OF BASILICATA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN; DEXAMETHASONE; ELTROMBOPAG; IMMUNOGLOBULIN; RITUXIMAB; ROMIPLOSTIM; STEROID;

ADULT; CASE REPORT; CROSS RESISTANCE; DRUG MEGADOSE; FEMALE; HUMAN; IDIOPATHIC THROMBOCYTOPENIC PURPURA; LETTER; MALE; PRIORITY JOURNAL; SALVAGE THERAPY; SPLENECTOMY; SUBCUTANEOUS HEMORRHAGE; THROMBOCYTE COUNT; THROMBOCYTOPOIESIS; TREATMENT DURATION; TREATMENT RESPONSE;

EID: 84874031577     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-11-465575     Document Type: Letter

References (5)

1. Imbach P, Crowther M. Thrombopoietin-receptor agonists for primary immune thrombocytopenia. N Engl J Med. 2011;365(8):734-741.
2. Liebman HA, Pullarkat V. Diagnosis and management of immune thrombocyto-penia in the era of thrombopoietin mimetics. Hematology. 2011;2011:384-390.
3. Kuter DJ. Biology and chemistry of thrombopoietin. Semin Hematol. 2010; 47(3):243-248.
4. McMillan R, Wang L, Tomer A, Nichol J, Pistillo J. Suppression of in vitro mega-karyocyte production by antiplatelet autoantobodies from adult patients with chronic ITP. Blood. 2004;103(4):1364-1369. (Pubitemid 38168649)
5. Aoki T, Harada Y, Matsubara E, et al. Thrombopoietin receptor agonists in refractory immune thrombocytopenia: differential responses to eltrombopag and romiplostim: a case report and possible explanations. J Clin Pharm Ther. 2012; 37(6):729-732.