WIN55, 212-2 promotes differentiation of oligodendrocyte precursor cells and improve remyelination through regulation of the phosphorylation level of the ERK 1/2 via cannabinoid receptor 1 after stroke-induced demyelination

Brain Research

Volumn 1491, Issue , 2013, Pages 225-235

  Sun, Jing ^a   Fang, Yinquan ^a   Chen, Tao ^a   Guo, Jingjing ^a   Yan, Jun ^a   Song, Shu ^b   Zhang, Luyong ^a   Liao, Hong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b Yancheng City No1 People's Hospital   (China)

Author keywords

212 2; Cannabinoid receptor 1; Myelin basic protein (MBP); Phospho extracellular signal regulated kinase 1 2 (p ERK 1 2); Transient middle cerebral artery occlusion (t MCAO); WIN55

Indexed keywords

CANNABINOID 1 RECEPTOR; CANNABINOID RECEPTOR AGONIST; MITOGEN ACTIVATED PROTEIN KINASE 1; MYELIN; MYELIN BASIC PROTEIN; RIMONABANT; UNCLASSIFIED DRUG; WIN55 212 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CELL SURVIVAL; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DEMYELINATION; IMMUNOCOMPETENT CELL; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL DIFFERENTIATION; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REMYELINIZATION; SIGNAL TRANSDUCTION; STEM CELL; WESTERN BLOTTING;

ANIMALS; ANTIMETABOLITES; BENZOXAZINES; BLOTTING, WESTERN; BRAIN ISCHEMIA; BROMODEOXYURIDINE; CANNABINOID RECEPTOR ANTAGONISTS; CELL DIFFERENTIATION; CELL SURVIVAL; DEMYELINATING DISEASES; IMMUNOHISTOCHEMISTRY; INDICATORS AND REAGENTS; MALE; MAP KINASE SIGNALING SYSTEM; MICROSCOPY, ELECTRON; MORPHOLINES; MYELIN BASIC PROTEIN; MYELIN SHEATH; NAPHTHALENES; OLIGODENDROGLIA; PHOSPHORYLATION; PIPERIDINES; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, CANNABINOID, CB1; STROKE;

EID: 84874022883     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.11.006     Document Type: Article

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