Admission hyperglycaemia and cerebral perfusion deficits in acute ischaemic stroke

Cerebrovascular Diseases

Volumn 35, Issue 2, 2013, Pages 163-167

  Luitse, Merel J A ^a   Van Seeters, Tom ^a   Horsch, Alexander D ^a   Kool, Hieke A ^a   Velthuis, Birgitta K ^a   Kappelle, L Jaap ^a   Biessels, Geert Jan ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Cerebral perfusion; Hyperglycaemia; Ischaemic stroke; Perfusion computed tomography

Indexed keywords

GLUCOSE;

ADULT; AGED; ARTICLE; BASAL GANGLION; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN PERFUSION; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; FEMALE; HEMISPHERE; HOSPITAL ADMISSION; HUMAN; HYPERGLYCEMIA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; BLOOD VOLUME; BRAIN BLOOD VOLUME; CEREBROVASCULAR ACCIDENT; CLINICAL ARTICLE; GLUCOSE BLOOD LEVEL; MIDDLE AGED; MORTALITY; RANKIN SCALE;

ADULT; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; BIOLOGICAL MARKERS; BLOOD GLUCOSE; BRAIN ISCHEMIA; CASE-CONTROL STUDIES; CEREBROVASCULAR CIRCULATION; CHI-SQUARE DISTRIBUTION; DISABILITY EVALUATION; FEMALE; HUMANS; HYPERGLYCEMIA; LOGISTIC MODELS; MALE; MIDDLE AGED; ODDS RATIO; PATIENT ADMISSION; PERFUSION IMAGING; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROSPECTIVE STUDIES; RISK FACTORS; STROKE; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84874015135     PISSN: 10159770     EISSN: 14219786     Source Type: Journal    
DOI: 10.1159/000346588     Document Type: Article

References (24)

1. Capes SE, Hunt D, Malmberg K, Pathak P, Gerstein HC: Stress hyperglycemia and prognosis of stroke in nondiabetic and diabetic patients: a systematic overview. Stroke 2001; 32: 2426-2432.
2. Uyttenboogaart M, Koch MW, Stewart RE, Vroomen PC, Luijckx GJ, De Keyser J: Moderate hyperglycaemia is associated with favourable outcome in acute lacunar stroke. Brain 2007; 130:1626-1630.
3. Bruno A, Williams LS, Kent TA: How important is hyperglycemia during acute brain infarction? Neurologist 2004; 10:195-200.
4. Luitse MJ, Biessels GJ, Rutten GE, Kappelle LJ: Diabetes, hyperglycaemia, and acute isch-aemic stroke. Lancet Neurol 2012; 11:261-271.
5. Putaala J, Sairanen T, Meretoja A, Lindsberg PJ, Tiainen M, Liebkind R, et al: Post-throm-bolytic hyperglycemia and 3-month outcome in acute ischemic stroke. Cerebrovasc Dis 2011; 31:83-92.
6. Baird TA, Parsons MW, Phanh T, Butcher KS, Desmond PM, Tress BM, et al: Persistent poststroke hyperglycemia is independently associated with infarct expansion and worse clinical outcome. Stroke 2003; 34:2208-2214.
7. Kruyt ND, Biessels GJ, Devries JH, Roos YB: Hyperglycemia in acute ischemic stroke: pathophysiology and clinical management. Nat Rev Neurol 2010; 6:145-155.
8. Parsons MW, Barber PA, Desmond PM, Baird TA, Darby DG, Byrnes G, et al: Acute hyper-glycemia adversely affects stroke outcome: a magnetic resonance imaging and spectrosco-py study. Ann Neurol 2002; 52:20-28.
9. Alvarez-Sabin J, Molina CA, Montaner J, Arenillas JF, Huertas R, Ribo M, et al: Effects of admission hyperglycemia on stroke outcome in reperfused tissue plasminogen activator-treated patients. Stroke 2003; 34:1235-1241.
10. Wintermark M, Reichhart M, Cuisenaire O, Maeder P, Thiran JP, Schnyder P, et al: Comparison of admission perfusion computed tomography and qualitative diffusion-and per-fusion-weighted magnetic resonance imaging in acute stroke patients. Stroke 2002; 33:2025-2031.
11. Wintermark M, Meuli R, Browaeys P, Reichhart M, Bogousslavsky J, Schnyder P, et al: Comparison of CT perfusion and angiogra-phy and MRI in selecting stroke patients for acute treatment. Neurology 2007; 68:694-697.
12. Schramm P, Schellinger PD, Klotz E, Kallenberg K, Fiebach JB, Kulkens S, et al: Comparison of perfusion computed tomography and computed tomography angiography source images with perfusion-weighted imaging and diffusion-weighted imaging in patients with acute stroke of less than 6 hours' duration. Stroke 2004; 35:1652-1658.
13. Wintermark M: Brain perfusion-CT in acute stroke patients. Eur Radiol 2005; 15(suppl 4):D28-D31.
14. Dankbaar JW, Rijsdijk M, van der Schaaf IC, Velthuis BK, Wermer MJ, Rinkel GJ: Relationship between vasospasm, cerebral perfusion, and delayed cerebral ischemia after an-eurysmal subarachnoid hemorrhage. Neuro-radiology 2009; 51:813-819.
15. Wintermark M, Flanders AE, Velthuis B, Meuli R, van Leeuwen M, Goldsher D, et al: Perfusion-CT assessment of infarct core and penumbra: receiver operating characteristic curve analysis in 130 patients suspected of acute hemispheric stroke. Stroke 2006; 37: 979-985.
16. Pexman JH, Barber PA, Hill MD, Sevick RJ, Demchuk AM, Hudon ME, et al: Use of the Alberta stroke program early CT score (ASPECTS) for assessing CT scans in patients with acute stroke. AJNR Am J Neuroradiol 2001; 22:1534-1542.
17. Kruyt ND, Nys GM, van der Worp HB, van Zandvoort MJ, Kappelle LJ, Biessels GJ: Hy-perglycemia and cognitive outcome after ischemic stroke. J Neurol Sci 2008; 270:141-147.
18. Scott JF, Robinson GM, French JM, O'Connell JE, Alberti KG, Gray CS: Glucose potassium insulin infusions in the treatment of acute stroke patients with mild to moderate hyper-glycemia: the glucose insulin in stroke trial (GIST). Stroke 1999; 30:793-799.
19. van Swieten JC, Koudstaal PJ, Visser MC, Schouten HJ, van Gijn J: Interobserver agreement for the assessment of handicap in stroke patients. Stroke 1988; 19:604-607.
20. Els T, Klisch J, Orszagh M, Hetzel A, Schulte-Monting J, Schumacher M, et al: Hyperglyce-mia in patients with focal cerebral ischemia after intravenous thrombolysis: influence on clinical outcome and infarct size. Cerebrovasc Dis 2002; 13:89-94.
21. Duckrow RB, Beard DC, Brennan RW: Regional cerebral blood flow decreases during chronic and acute hyperglycemia. Stroke 1987; 18:52-58.
22. Kawai N, Keep RF, Betz AL, Nagao S: Hyper-glycemia induces progressive changes in the cerebral microvasculature and blood-brain barrier transport during focal cerebral ischemia. Acta Neurochir Suppl 1998; 71:219-221.
23. Quast MJ, Wei J, Huang NC, Brunder DG, Sell SL, Gonzalez JM, et al: Perfusion deficit parallels exacerbation of cerebral ischemia/reperfusion injury in hyperglycemic rats. J Cereb Blood Flow Metab 1997; 17:553-559.
24. Yip PK, He YY, Hsu CY, Garg N, Marangos P, Hogan EL: Effect of plasma glucose on infarct size in focal cerebral ischemia-reperfu-sion. Neurology 1991; 41:899-905.