Dopamine prevents impairment of autoregulation after traumatic brain injury in the newborn pig through inhibition of up-regulation of endothelin-1 and extracellular signal-regulated kinase mitogen-activated protein kinase

Pediatric Critical Care Medicine

Volumn 14, Issue 2, 2013, Pages

  Armstead, William M ^a   Riley, John ^a   Vavilala, Monica S ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

cerebral autoregulation; cerebral perfusion pressure; dopamine; endothelin; signal transduction; traumatic brain injur

Indexed keywords

DOPAMINE; ENDOTHELIN 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHENYLEPHRINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY DIAMETER; ARTICLE; AUTOREGULATION; BRAIN PERFUSION; CONTROLLED STUDY; EXPERIMENTAL PIG; FEMALE; HYPOTENSION; MALE; MEAN ARTERIAL PRESSURE; NEWBORN; NEWBORN DISEASE; NONHUMAN; PARIETAL CORTEX; PERFUSION PRESSURE; PIA ARTERY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN CEREBROSPINAL FLUID LEVEL; TRAUMATIC BRAIN INJURY; UPREGULATION;

ANALYSIS OF VARIANCE; ANIMALS; BLOOD PRESSURE; BRAIN INJURIES; CEREBROVASCULAR CIRCULATION; DOPAMINE; ENDOTHELIN-1; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; HYPOTENSION; MALE; MAP KINASE SIGNALING SYSTEM; SEX FACTORS; SWINE; SYMPATHOMIMETICS; UP-REGULATION; VASODILATION;

EID: 84874000709     PISSN: 15297535     EISSN: 19473893     Source Type: Journal    
DOI: 10.1097/PCC.0b013e3182712b44     Document Type: Article

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