Encapsulation of Acyclovir in new carboxylated cyclodextrin-based nanosponges improves the agent's antiviral efficacy

International Journal of Pharmaceutics

Volumn 443, Issue 1-2, 2013, Pages 262-272

  Lembo, David ^a   Swaminathan, Shankar ^a,b   Donalisio, Manuela ^a   Civra, Andrea ^a   Pastero, Linda ^a   Aquilano, Dino ^a   Vavia, Pradeep ^b   Trotta, Francesco ^b   Cavalli, Roberta ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Acyclovir; Antiviral activity; Cyclodextrin; Nanosponges; Prolonged release

Indexed keywords

ACICLOVIR; BETA CYCLODEXTRIN DERIVATIVE;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; COMPLEX FORMATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DISTRIBUTION; DRUG EFFICACY; ENCAPSULATION; FOURIER TRANSFORM INFRARED PHOTOACOUSTIC SPECTROSCOPY; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; STATIC ELECTRICITY; X RAY POWDER DIFFRACTION;

ACYCLOVIR; ANIMALS; ANTIVIRAL AGENTS; BETA-CYCLODEXTRINS; CARBOXYLIC ACIDS; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; CROSS-LINKING REAGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; DRUG COMPOUNDING; HERPESVIRUS 1, HUMAN; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; NANOPARTICLES; PARTICLE SIZE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SURFACE PROPERTIES; VERO CELLS; VIRAL PLAQUE ASSAY;

EID: 84873999763     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.12.031     Document Type: Article

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