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Volumn 75, Issue 2, 2010, Pages 398-404
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Ammonium methacrylate units polymer content and their effect on acyclovir colloidal nanoparticles properties and bioavailability in human volunteers
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Author keywords
Acyclovir; Bioavailability; Eudragit RS and RL; Human volunteers; LC MS MS; Nanoparticles; Suspension
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Indexed keywords
AMMONIUM GROUPS;
COLLOIDAL NANOPARTICLES;
COMMERCIAL PRODUCTS;
ENCAPSULATION EFFICIENCY;
EUDRAGIT;
HUMAN VOLUNTEERS;
IN-VITRO DISSOLUTION;
LC-MS/MS;
LOWER LIMIT OF QUANTIFICATIONS;
NANO-SUSPENSIONS;
NANOPARTICLES SUSPENSION;
ORAL ABSORPTION;
POLYMER CONTENT;
RELATIVE BIOAVAILABILITY;
AMMONIUM COMPOUNDS;
BIOCHEMISTRY;
DISSOLUTION;
ENCAPSULATION;
FLUORINE CONTAINING POLYMERS;
NANOPARTICLES;
POLYMERS;
RAPID SOLIDIFICATION;
VIRUSES;
DRUG PRODUCTS;
ACICLOVIR;
AMMONIA;
EUDRAGIT;
METHACRYLIC ACID;
ADULT;
AREA UNDER THE CURVE;
ARTICLE;
CLINICAL TRIAL;
CONTROLLED CLINICAL TRIAL;
CONTROLLED DRUG RELEASE;
CONTROLLED STUDY;
CROSSOVER PROCEDURE;
DRUG ABSORPTION;
DRUG BIOAVAILABILITY;
DRUG SOLUBILITY;
ENCAPSULATION;
HALF LIFE TIME;
HUMAN;
HUMAN EXPERIMENT;
LIQUID CHROMATOGRAPHY;
MALE;
MASS SPECTROMETRY;
MAXIMUM PLASMA CONCENTRATION;
MEAN RESIDENCE TIME;
NANOPHARMACEUTICS;
NORMAL HUMAN;
PARTICLE SIZE;
PLASMA CONCENTRATION-TIME CURVE;
PRIORITY JOURNAL;
RANDOMIZED CONTROLLED TRIAL;
SINGLE DRUG DOSE;
SURFACE CHARGE;
TIME TO MAXIMUM PLASMA CONCENTRATION;
ZETA POTENTIAL;
ACYCLOVIR;
ADMINISTRATION, ORAL;
ADULT;
BIOLOGICAL AVAILABILITY;
BUFFERS;
CALORIMETRY, DIFFERENTIAL SCANNING;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
CHROMATOGRAPHY, LIQUID;
COLLOIDS;
FLUOROBENZENES;
HUMANS;
HYDROGEN-ION CONCENTRATION;
KINETICS;
MALE;
MASS SPECTROMETRY;
METHACRYLATES;
NANOPARTICLES;
PARTICLE SIZE;
POLYMERS;
PYRIMIDINES;
REFERENCE STANDARDS;
SULFONAMIDES;
TIME FACTORS;
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EID: 70549094206
PISSN: 09277765
EISSN: None
Source Type: Journal
DOI: 10.1016/j.colsurfb.2009.08.050 Document Type: Article |
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Times cited : (23)
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References (24)
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