메뉴 건너뛰기




Volumn 37, Issue 3, 2013, Pages 413-420

Immunohistochemical analysis of BRAFV600E expression of primary and metastatic melanoma and comparison with mutation status and melanocyte differentiation antigens of metastatic lesions

Author keywords

BRAFV600E; immunohistochemistry; melanoma

Indexed keywords

B RAF KINASE; BRAF PROTEIN, HUMAN; DIAGNOSTIC AGENT; MONOCLONAL ANTIBODY; TUMOR MARKER;

EID: 84873993511     PISSN: 01475185     EISSN: 15320979     Source Type: Journal    
DOI: 10.1097/PAS.0b013e318271249e     Document Type: Article
Times cited : (93)

References (38)
  • 1
    • 0037228055 scopus 로고    scopus 로고
    • High frequency of BRAF mutations in nevi
    • Pollock PM, Harper UL, Hansen KS, et al. High frequency of BRAF mutations in nevi. Nat Genet. 2003;33:19-20.
    • (2003) Nat Genet , vol.33 , pp. 19-20
    • Pollock, P.M.1    Harper, U.L.2    Hansen, K.S.3
  • 2
    • 84859463692 scopus 로고    scopus 로고
    • Targeting NRAS in melanoma
    • Kelleher FC, McArthur GA. Targeting NRAS in melanoma. Cancer J. 2012;18:132-136.
    • (2012) Cancer J , vol.18 , pp. 132-136
    • Kelleher, F.C.1    McArthur, G.A.2
  • 3
    • 79958066836 scopus 로고    scopus 로고
    • KIT as a therapeutic target in metastatic melanoma
    • Carvajal RD, Antonescu CR,Wolchok JD, et al. KIT as a therapeutic target in metastatic melanoma. JAMA. 2011;305:2327-2334.
    • (2011) JAMA , vol.305 , pp. 2327-2334
    • Carvajal, R.D.1    Antonescu, C.R.2    Wolchok, J.D.3
  • 4
    • 59049107421 scopus 로고    scopus 로고
    • Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi
    • Van Raamsdonk CD, Bezrookove V, Green G, et al. Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi. Nature. 2009;457:599-602.
    • (2009) Nature , vol.457 , pp. 599-602
    • Van Raamsdonk, C.D.1    Bezrookove, V.2    Green, G.3
  • 6
    • 84861427327 scopus 로고    scopus 로고
    • Melanoma genome sequencing reveals frequent PREX2 mutations
    • Berger MF, Hodis E, Heffernan TP, et al. Melanoma genome sequencing reveals frequent PREX2 mutations. Nature. 2012;485: 502-506.
    • (2012) Nature , vol.485 , pp. 502-506
    • Berger, M.F.1    Hodis, E.2    Heffernan, T.P.3
  • 7
    • 84864452205 scopus 로고    scopus 로고
    • BRAF mutation detection in metastatic melanoma
    • Dietel M, Enk A, Lehmann A, et al. BRAF mutation detection in metastatic melanoma. Pathologe. 2012;33:352-356.
    • (2012) Pathologe , vol.33 , pp. 352-356
    • Dietel, M.1    Enk, A.2    Lehmann, A.3
  • 8
    • 84855952269 scopus 로고    scopus 로고
    • Targeting metastatic melanoma
    • Flaherty KT. Targeting metastatic melanoma. Annu Rev Med. 2012;63:171-183.
    • (2012) Annu Rev Med , vol.63 , pp. 171-183
    • Flaherty, K.T.1
  • 9
    • 84868203567 scopus 로고    scopus 로고
    • Dividing and conquering: Controlling advanced melanoma by targeting oncogene-defined subsets
    • June 3 [Epub ahead of print]
    • Flaherty KT. Dividing and conquering: controlling advanced melanoma by targeting oncogene-defined subsets. Clin Exp Metastasis. 2012; June 3 [Epub ahead of print].
    • (2012) Clin Exp Metastasis
    • Flaherty, K.T.1
  • 10
    • 79959580390 scopus 로고    scopus 로고
    • Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody
    • Capper D, Preusser M, Habel A, et al. Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody. Acta Neuropathol. 2011;122: 11-19.
    • (2011) Acta Neuropathol , vol.122 , pp. 11-19
    • Capper, D.1    Preusser, M.2    Habel, A.3
  • 11
    • 81155124389 scopus 로고    scopus 로고
    • The SWOT of BRAF inhibition in melanoma: RAF inhibitors, MEK inhibitors or both?
    • Nissan MH, Solit DB. The "SWOT" of BRAF inhibition in melanoma: RAF inhibitors, MEK inhibitors or both? Curr Oncol Rep. 2011;13:479-487.
    • (2011) Curr Oncol Rep , vol.13 , pp. 479-487
    • Nissan, M.H.1    Solit, D.B.2
  • 12
    • 77955493250 scopus 로고    scopus 로고
    • Incidence of the V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic response to the specific BRAF inhibitor PLX4032
    • Rubinstein JC, Sznol M, Pavlick AC, et al. Incidence of the V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic response to the specific BRAF inhibitor PLX4032. J Transl Med. 2010;8:67.
    • (2010) J Transl Med , vol.8 , pp. 67
    • Rubinstein, J.C.1    Sznol, M.2    Pavlick, A.C.3
  • 13
    • 84863643140 scopus 로고    scopus 로고
    • Incidence of BRAF p.Val600Glu and p.Val600Lys mutations in a consecutive series of 183 metastatic melanoma patients from a high incidence region
    • Amanuel B, Grieu F, Kular J, et al. Incidence of BRAF p.Val600Glu and p.Val600Lys mutations in a consecutive series of 183 metastatic melanoma patients from a high incidence region. Pathology. 2012;44:357-359.
    • (2012) Pathology , vol.44 , pp. 357-359
    • Amanuel, B.1    Grieu, F.2    Kular, J.3
  • 14
    • 84864722943 scopus 로고    scopus 로고
    • NRAS mutation status is an independent prognostic factor in metastatic melanoma
    • Jakob JA, Bassett RL Jr, Ng CS, et al. NRAS mutation status is an independent prognostic factor in metastatic melanoma. Cancer. 2012;118:4014-4023.
    • (2012) Cancer , vol.118 , pp. 4014-4023
    • Jakob, J.A.1    Bassett Jr., R.L.2    Ng, C.S.3
  • 15
    • 84855460517 scopus 로고    scopus 로고
    • BRAF inhibitors for the treatment of metastatic melanoma: Clinical trials and mechanisms of resistance
    • Alcala AM, Flaherty KT. BRAF inhibitors for the treatment of metastatic melanoma: clinical trials and mechanisms of resistance. Clin Cancer Res. 2012;18:33-39.
    • (2012) Clin Cancer Res , vol.18 , pp. 33-39
    • Alcala, A.M.1    Flaherty, K.T.2
  • 16
    • 77956030786 scopus 로고    scopus 로고
    • Inhibition of mutated, activated BRAF in metastatic melanoma
    • Flaherty KT, Puzanov I, Kim KB, et al. Inhibition of mutated, activated BRAF in metastatic melanoma. N Engl J Med. 2010;363: 809-819.
    • (2010) N Engl J Med , vol.363 , pp. 809-819
    • Flaherty, K.T.1    Puzanov, I.2    Kim, K.B.3
  • 17
    • 79959795786 scopus 로고    scopus 로고
    • Improved survival with vemurafenib in melanoma with BRAF V600E mutation
    • Chapman PB, Hauschild A, Robert C, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med. 2011;364:2507-2516.
    • (2011) N Engl J Med , vol.364 , pp. 2507-2516
    • Chapman, P.B.1    Hauschild, A.2    Robert, C.3
  • 18
    • 84859471285 scopus 로고    scopus 로고
    • Molecular testing in melanoma
    • Wilson MA, Nathanson KL. Molecular testing in melanoma. Cancer J. 2012;18:117-123.
    • (2012) Cancer J , vol.18 , pp. 117-123
    • Wilson, M.A.1    Nathanson, K.L.2
  • 19
    • 84857030136 scopus 로고    scopus 로고
    • Immunohistochemical testing of BRAF V600E status in 1,120 tumor tissue samples of patients with brain metastases
    • Capper D, Berghoff AS, Magerle M, et al. Immunohistochemical testing of BRAF V600E status in 1,120 tumor tissue samples of patients with brain metastases. Acta Neuropathol. 2012;123: 223-233.
    • (2012) Acta Neuropathol , vol.123 , pp. 223-233
    • Capper, D.1    Berghoff, A.S.2    Magerle, M.3
  • 20
    • 79954441895 scopus 로고    scopus 로고
    • Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma
    • Schindler G, Capper D, Meyer J, et al. Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma. Acta Neuropathol. 2011;121: 397-405.
    • (2011) Acta Neuropathol , vol.121 , pp. 397-405
    • Schindler, G.1    Capper, D.2    Meyer, J.3
  • 21
    • 84870067191 scopus 로고    scopus 로고
    • Application of a BRAF V600E mutation-specific antibody for the diagnosis of hairy cell leukemia
    • April 22 [Epub ahead of print]
    • Andrulis M, Penzel R, Weichert W, et al. Application of a BRAF V600E mutation-specific antibody for the diagnosis of hairy cell leukemia. Am J Surg Pathol. 2012; April 22 [Epub ahead of print].
    • (2012) Am J Surg Pathol
    • Andrulis, M.1    Penzel, R.2    Weichert, W.3
  • 22
    • 0035110161 scopus 로고    scopus 로고
    • Analysis of microphthalmia transcription factor expression in normal tissues and tumors, and comparison of its expression with S-100 protein, gp100, and tyrosinase in desmoplastic malignant melanoma
    • Busam KJ, Iversen K, Coplan KC, et al. Analysis of microphthalmia transcription factor expression in normal tissues and tumors, and comparison of its expression with S-100 protein, gp100, and tyrosinase in desmoplastic malignant melanoma. Am J Surg Pathol. 2001;25:197-204.
    • (2001) Am J Surg Pathol , vol.25 , pp. 197-204
    • Busam, K.J.1    Iversen, K.2    Coplan, K.C.3
  • 23
    • 84858207885 scopus 로고    scopus 로고
    • Vemurafenib: The road to personalized medicine in melanoma
    • Amaria RN, Lewis KD, Jimeno A. Vemurafenib: the road to personalized medicine in melanoma. Drugs Today (Barc). 2012;48: 109-118.
    • (2012) Drugs Today (Barc) , vol.48 , pp. 109-118
    • Amaria, R.N.1    Lewis, K.D.2    Jimeno, A.3
  • 24
    • 78651071913 scopus 로고    scopus 로고
    • Detection of KRAS and BRAF mutations in colorectal carcinoma roles for high-sensitivity locked nucleic acid-PCR sequencing and broad-spectrum mass spectrometry genotyping
    • Arcila M, Lau C, Nafa K, et al. Detection of KRAS and BRAF mutations in colorectal carcinoma roles for high-sensitivity locked nucleic acid-PCR sequencing and broad-spectrum mass spectrometry genotyping. J Mol Diagn. 2011;13:64-73.
    • (2011) J Mol Diagn , vol.13 , pp. 64-73
    • Arcila, M.1    Lau, C.2    Nafa, K.3
  • 25
    • 33845592531 scopus 로고    scopus 로고
    • NRAS and BRAF mutations in melanoma tumours in relation to clinical characteristics: A study based on mutation screening by pyrosequencing
    • Edlundh-Rose E, Egyhazi S, Omholt K, et al. NRAS and BRAF mutations in melanoma tumours in relation to clinical characteristics: a study based on mutation screening by pyrosequencing. Melanoma Res. 2006;16:471-478.
    • (2006) Melanoma Res , vol.16 , pp. 471-478
    • Edlundh-Rose, E.1    Egyhazi, S.2    Omholt, K.3
  • 27
    • 78650303507 scopus 로고    scopus 로고
    • Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
    • Nazarian R, Shi H, Wang Q, et al. Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation. Nature. 2010;468:973-977.
    • (2010) Nature , vol.468 , pp. 973-977
    • Nazarian, R.1    Shi, H.2    Wang, Q.3
  • 28
    • 80051625929 scopus 로고    scopus 로고
    • Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling
    • Wagle N, Emery C, Berger MF, et al. Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling. J Clin Oncol. 2011;29:3085-3096.
    • (2011) J Clin Oncol , vol.29 , pp. 3085-3096
    • Wagle, N.1    Emery, C.2    Berger, M.F.3
  • 29
    • 78650309875 scopus 로고    scopus 로고
    • COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
    • Johannessen CM, Boehm JS, Kim SY, et al. COT drives resistance to RAF inhibition through MAP kinase pathway reactivation. Nature. 2010;468:968-972.
    • (2010) Nature , vol.468 , pp. 968-972
    • Johannessen, C.M.1    Boehm, J.S.2    Kim, S.Y.3
  • 30
    • 84859183431 scopus 로고    scopus 로고
    • Melanoma whole-exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance
    • Shi H, Moriceau G, Kong X, et al. Melanoma whole-exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance. Nat Commun. 2012;3:724.
    • (2012) Nat Commun , vol.3 , pp. 724
    • Shi, H.1    Moriceau, G.2    Kong, X.3
  • 31
    • 83455254767 scopus 로고    scopus 로고
    • RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF (V600E)
    • Poulikakos PI, Persaud Y, Janakiraman M, et al. RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E). Nature. 2011;480:387-390.
    • (2011) Nature , vol.480 , pp. 387-390
    • Poulikakos, P.I.1    Persaud, Y.2    Janakiraman, M.3
  • 32
    • 84855302859 scopus 로고    scopus 로고
    • Intra-and inter-tumor heterogeneity of BRAF(V600E))mutations in primary and metastatic melanoma
    • Yancovitz M, Litterman A, Yoon J, et al. Intra-and inter-tumor heterogeneity of BRAF(V600E))mutations in primary and metastatic melanoma. PLoS One. 2012;7:e29336.
    • (2012) PLoS One , vol.7
    • Yancovitz, M.1    Litterman, A.2    Yoon, J.3
  • 33
    • 33746263912 scopus 로고    scopus 로고
    • BRAF and NRAS mutations in melanoma and melanocytic nevi
    • Poynter JN, Elder JT, Fullen DR, et al. BRAF and NRAS mutations in melanoma and melanocytic nevi. Melanoma Res. 2006;16:267-273.
    • (2006) Melanoma Res , vol.16 , pp. 267-273
    • Poynter, J.N.1    Elder, J.T.2    Fullen, D.R.3
  • 34
    • 0346728596 scopus 로고    scopus 로고
    • Determinants of BRAF mutations in primary melanomas
    • Maldonado JL, Fridlyand J, Patel H, et al. Determinants of BRAF mutations in primary melanomas. J Natl Cancer Inst. 2003;95: 1878-1890.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 1878-1890
    • Maldonado, J.L.1    Fridlyand, J.2    Patel, H.3
  • 35
    • 79955479382 scopus 로고    scopus 로고
    • Evolving concepts in melanoma classification and their relevance to multidisciplinary melanoma patient care
    • Scolyer RA, Long GV, Thompson JF. Evolving concepts in melanoma classification and their relevance to multidisciplinary melanoma patient care. Mol Oncol. 2011;5:124-136.
    • (2011) Mol Oncol , vol.5 , pp. 124-136
    • Scolyer, R.A.1    Long, G.V.2    Thompson, J.F.3
  • 36
    • 83255191650 scopus 로고    scopus 로고
    • Prevalence of BRAF V600E mutation in Chinese melanoma patients: Large scale analysis of BRAF and NRAS mutations in a 432-case cohort
    • Si L, Kong Y, Xu X, et al. Prevalence of BRAF V600E mutation in Chinese melanoma patients: large scale analysis of BRAF and NRAS mutations in a 432-case cohort. Eur J Cancer. 2012;48: 94-100.
    • (2012) Eur J Cancer , vol.48 , pp. 94-100
    • Si, L.1    Kong, Y.2    Xu, X.3
  • 37
    • 27844567142 scopus 로고    scopus 로고
    • Distinct sets of genetic alterations in melanoma
    • Curtin JA, Fridlyand J, Kageshita T, et al. Distinct sets of genetic alterations in melanoma. N Engl J Med. 2005;353:2135-2147.
    • (2005) N Engl J Med , vol.353 , pp. 2135-2147
    • Curtin, J.A.1    Fridlyand, J.2    Kageshita, T.3
  • 38
    • 78049305326 scopus 로고    scopus 로고
    • Genetic and morphologic features for melanoma classification
    • Broekaert SM, Roy R, Okamoto I, et al. Genetic and morphologic features for melanoma classification. Pigment Cell Melanoma Res. 2010;23:763-770.
    • (2010) Pigment Cell Melanoma Res , vol.23 , pp. 763-770
    • Broekaert, S.M.1    Roy, R.2    Okamoto, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.