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Volumn 48, Issue 1, 2012, Pages 94-100

Prevalence of BRAF V600E mutation in Chinese melanoma patients: Large scale analysis of BRAF and NRAS mutations in a 432-case cohort

Author keywords

BRAF; Melanoma; Mutation; NRAS; Overall survival

Indexed keywords

B RAF KINASE; B RAF KINASE INHIBITOR; GENOMIC DNA;

EID: 83255191650     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2011.06.056     Document Type: Article
Times cited : (229)

References (40)
  • 2
    • 0023256456 scopus 로고
    • Prevalence of ras gene mutations in human colorectal cancers
    • J.L. Bos, E.R. Fearon, and S.R. Hamilton Prevalence of ras gene mutations in human colorectal cancers Nature 327 1987 293 297
    • (1987) Nature , vol.327 , pp. 293-297
    • Bos, J.L.1    Fearon, E.R.2    Hamilton, S.R.3
  • 3
    • 0024407112 scopus 로고
    • N-ras mutations in human cutaneous melanoma from sun-exposed body sites
    • L.J. van ′t Veer, B.M. Burgering, and R. Versteeg N-ras mutations in human cutaneous melanoma from sun-exposed body sites Mol Cell Biol 9 1989 3114 3116
    • (1989) Mol Cell Biol , vol.9 , pp. 3114-3116
    • Van Veer, L.J.1    Burgering, B.M.2    Versteeg, R.3
  • 4
    • 0024438925 scopus 로고
    • Analysis of ras oncogenes in malignant melanoma and precursor lesions: Correlation of point mutations with differentiation phenotype
    • A.P. Albino, D.M. Nanus, and I.R. Mentle Analysis of ras oncogenes in malignant melanoma and precursor lesions: correlation of point mutations with differentiation phenotype Oncogene 4 1989 1363 1374
    • (1989) Oncogene , vol.4 , pp. 1363-1374
    • Albino, A.P.1    Nanus, D.M.2    Mentle, I.R.3
  • 5
    • 0028178840 scopus 로고
    • Ras mutations in human melanoma: A marker of malignant progression
    • N.J. Ball, J.J. Yohn, and J.G. Morelli Ras mutations in human melanoma: a marker of malignant progression J Invest Dermatol 102 1994 285 290
    • (1994) J Invest Dermatol , vol.102 , pp. 285-290
    • Ball, N.J.1    Yohn, J.J.2    Morelli, J.G.3
  • 6
    • 0029781017 scopus 로고    scopus 로고
    • Relevance of ultraviolet-induced N-ras oncogene point mutations in development of primary human cutaneous melanoma
    • A. van Elsas, S.F. Zerp, and S. van der Flier Relevance of ultraviolet-induced N-ras oncogene point mutations in development of primary human cutaneous melanoma Am J Pathol 149 1996 883 893
    • (1996) Am J Pathol , vol.149 , pp. 883-893
    • Van Elsas, A.1    Zerp, S.F.2    Van Der Flier, S.3
  • 7
    • 0031738326 scopus 로고    scopus 로고
    • N-ras mutations are common in melanomas from sun-exposed skin of humans but rare in mucosal membranes or unexposed skin
    • S. Jiveskog, B. Ragnarsson-Olding, A. Platz, and U. Ringborg N-ras mutations are common in melanomas from sun-exposed skin of humans but rare in mucosal membranes or unexposed skin J Invest Dermatol 111 1998 757 761
    • (1998) J Invest Dermatol , vol.111 , pp. 757-761
    • Jiveskog, S.1    Ragnarsson-Olding, B.2    Platz, A.3    Ringborg, U.4
  • 8
    • 0036850146 scopus 로고    scopus 로고
    • Screening of N-ras codon 61 mutations in paired primary and metastatic cutaneous melanomas: Mutations occur early and persist throughout tumor progression
    • K. Omholt, S. Karsberg, and A. Platz Screening of N-ras codon 61 mutations in paired primary and metastatic cutaneous melanomas: mutations occur early and persist throughout tumor progression Clin Cancer Res 8 2002 3468 3474
    • (2002) Clin Cancer Res , vol.8 , pp. 3468-3474
    • Omholt, K.1    Karsberg, S.2    Platz, A.3
  • 9
    • 0036894746 scopus 로고    scopus 로고
    • BRAF and RAS mutations in human lung cancer and melanoma
    • M.S. Brose, P. Volpe, and M. Feldman BRAF and RAS mutations in human lung cancer and melanoma Cancer Res 62 2002 6997 7000
    • (2002) Cancer Res , vol.62 , pp. 6997-7000
    • Brose, M.S.1    Volpe, P.2    Feldman, M.3
  • 10
    • 0042173193 scopus 로고    scopus 로고
    • Analysis of BRAF and N-RAS mutations in metastatic melanoma tissues
    • A. Gorden, I. Osman, and W. Gai Analysis of BRAF and N-RAS mutations in metastatic melanoma tissues Cancer Res 63 2003 3955 3957
    • (2003) Cancer Res , vol.63 , pp. 3955-3957
    • Gorden, A.1    Osman, I.2    Gai, W.3
  • 11
    • 0041333110 scopus 로고    scopus 로고
    • BRAF mutations in metastatic melanoma: A possible association with clinical outcome
    • R. Kumar, S. Angelini, and K. Czene BRAF mutations in metastatic melanoma: a possible association with clinical outcome Clin Cancer Res 9 2003 3362 3368
    • (2003) Clin Cancer Res , vol.9 , pp. 3362-3368
    • Kumar, R.1    Angelini, S.2    Czene, K.3
  • 12
    • 1842428668 scopus 로고    scopus 로고
    • Incidence of BRAF oncogene mutation and clinical relevance for primary cutaneous melanomas
    • M. Shinozaki, A. Fujimoto, D.L. Morton, and D.S. Hoon Incidence of BRAF oncogene mutation and clinical relevance for primary cutaneous melanomas Clin Cancer Res 10 2004 1753 1757
    • (2004) Clin Cancer Res , vol.10 , pp. 1753-1757
    • Shinozaki, M.1    Fujimoto, A.2    Morton, D.L.3    Hoon, D.S.4
  • 13
    • 2942607408 scopus 로고    scopus 로고
    • Constitutive activation of the Ras-Raf signaling pathway in metastatic melanoma is associated with poor prognosis
    • R. Houben, J.C. Becker, and A. Kappel Constitutive activation of the Ras-Raf signaling pathway in metastatic melanoma is associated with poor prognosis J Carcinog 3 2004 6
    • (2004) J Carcinog , vol.3 , pp. 6
    • Houben, R.1    Becker, J.C.2    Kappel, A.3
  • 14
    • 18144409161 scopus 로고    scopus 로고
    • Clinical significance of BRAF mutations in metastatic melanoma
    • D.Z. Chang, K.S. Panageas, and I. Osman Clinical significance of BRAF mutations in metastatic melanoma J Transl Med 2 2004 46
    • (2004) J Transl Med , vol.2 , pp. 46
    • Chang, D.Z.1    Panageas, K.S.2    Osman, I.3
  • 15
    • 24344490303 scopus 로고    scopus 로고
    • BRAF and NRAS mutations are frequent in nodular melanoma but are not associated with tumor cell proliferation or patient survival
    • L.A. Akslen, S. Angelini, and O. Straume BRAF and NRAS mutations are frequent in nodular melanoma but are not associated with tumor cell proliferation or patient survival J Invest Dermatol 125 2005 312 317
    • (2005) J Invest Dermatol , vol.125 , pp. 312-317
    • Akslen, L.A.1    Angelini, S.2    Straume, O.3
  • 16
    • 27644599364 scopus 로고    scopus 로고
    • Preponderance of the oncogenic V599E and V599K mutations in the B-raf kinase domain is enhanced in melanoma lymph node metastases
    • M. Kirschner, B. Helmke, and H. Starz Preponderance of the oncogenic V599E and V599K mutations in the B-raf kinase domain is enhanced in melanoma lymph node metastases Melanoma Res 15 2005 427 434
    • (2005) Melanoma Res , vol.15 , pp. 427-434
    • Kirschner, M.1    Helmke, B.2    Starz, H.3
  • 17
    • 27844567142 scopus 로고    scopus 로고
    • Distinct sets of genetic alterations in melanoma
    • J.A. Curtin, J. Fridlyand, and T. Kageshita Distinct sets of genetic alterations in melanoma N Engl J Med 353 2005 2135 2147
    • (2005) N Engl J Med , vol.353 , pp. 2135-2147
    • Curtin, J.A.1    Fridlyand, J.2    Kageshita, T.3
  • 18
    • 33845592531 scopus 로고    scopus 로고
    • NRAS and BRAF mutations in melanoma tumours in relation to clinical characteristics: A study based on mutation screening by pyrosequencing
    • E. Edlundh-Rose, S. Egyházi, and K. Omholt NRAS and BRAF mutations in melanoma tumours in relation to clinical characteristics: a study based on mutation screening by pyrosequencing Melanoma Res 16 2006 471 478
    • (2006) Melanoma Res , vol.16 , pp. 471-478
    • Edlundh-Rose, E.1    Egyházi, S.2    Omholt, K.3
  • 19
    • 33947230256 scopus 로고    scopus 로고
    • Distinct clinical and pathological features are associated with the BRAF(T1799A(V600E)) mutation in primary melanoma
    • W. Liu, J.W. Kelly, and M. Trivett Distinct clinical and pathological features are associated with the BRAF(T1799A(V600E)) mutation in primary melanoma J Invest Dermatol 127 2007 900 905
    • (2007) J Invest Dermatol , vol.127 , pp. 900-905
    • Liu, W.1    Kelly, J.W.2    Trivett, M.3
  • 20
    • 72049114938 scopus 로고    scopus 로고
    • The association between MC1R genotype and BRAF mutation status in cutaneous melanoma: Findings from an Australian population
    • E. Hacker, N.K. Hayward, T. Dumenil, M.R. James, and D.C. Whiteman The association between MC1R genotype and BRAF mutation status in cutaneous melanoma: findings from an Australian population J Invest Dermatol 130 2010 241 248
    • (2010) J Invest Dermatol , vol.130 , pp. 241-248
    • Hacker, E.1    Hayward, N.K.2    Dumenil, T.3    James, M.R.4    Whiteman, D.C.5
  • 21
    • 79251474400 scopus 로고    scopus 로고
    • Clinical correlates of NRAS and BRAF mutations in primary human melanoma
    • J.A. Ellerhorst, V.R. Greene, and S. Ekmekcioglu Clinical correlates of NRAS and BRAF mutations in primary human melanoma Clin Cancer Res 17 2011 229 235
    • (2011) Clin Cancer Res , vol.17 , pp. 229-235
    • Ellerhorst, J.A.1    Greene, V.R.2    Ekmekcioglu, S.3
  • 22
    • 84978034236 scopus 로고    scopus 로고
    • Prognostic and clinicopathologic associations of oncogenic BRAF in metastatic melanoma
    • G.V. Long, A.M. Menzies, and A.M. Nagrial Prognostic and clinicopathologic associations of oncogenic BRAF in metastatic melanoma J Clin Oncol 29 2011 1239 1246
    • (2011) J Clin Oncol , vol.29 , pp. 1239-1246
    • Long, G.V.1    Menzies, A.M.2    Nagrial, A.M.3
  • 23
    • 34547783340 scopus 로고    scopus 로고
    • Skin cancer in individuals of African, Asian, Latin-American, and American-Indian descent: Differences in incidence, clinical presentation, and survival compared to Caucasians
    • K. Byrd-Miles, E.L. Toombs, and G.L. Peck Skin cancer in individuals of African, Asian, Latin-American, and American-Indian descent: differences in incidence, clinical presentation, and survival compared to Caucasians J Drugs Dermatol 6 2007 10 16
    • (2007) J Drugs Dermatol , vol.6 , pp. 10-16
    • Byrd-Miles, K.1    Toombs, E.L.2    Peck, G.L.3
  • 24
    • 16544379778 scopus 로고    scopus 로고
    • Impact of ulceration in stages i to III cutaneous melanoma as staged by the American Joint Committee on Cancer Staging System: An analysis of the German Central Malignant Melanoma Registry
    • T.K. Eigentler, P.G. Buettner, U. Leiter, and C. Garbe Impact of ulceration in stages I to III cutaneous melanoma as staged by the American Joint Committee on Cancer Staging System: an analysis of the German Central Malignant Melanoma Registry J Clin Oncol 22 2004 4376 4383
    • (2004) J Clin Oncol , vol.22 , pp. 4376-4383
    • Eigentler, T.K.1    Buettner, P.G.2    Leiter, U.3    Garbe, C.4
  • 26
    • 40149090144 scopus 로고    scopus 로고
    • Statistical profiles of malignant melanoma and other skin cancers in Japan: 2007 update
    • K. Ishihara, T. Saida, and F. Otsuka Statistical profiles of malignant melanoma and other skin cancers in Japan: 2007 update Int J Clin Oncol 13 2008 33 41
    • (2008) Int J Clin Oncol , vol.13 , pp. 33-41
    • Ishihara, K.1    Saida, T.2    Otsuka, F.3
  • 27
    • 79951960017 scopus 로고    scopus 로고
    • Clinical presentation, histology, prognoses of malignant melanoma in ethnic Chinese: A study of 522 consecutive cases
    • Z. Chi, S. Li, and X. Sheng Clinical presentation, histology, prognoses of malignant melanoma in ethnic Chinese: a study of 522 consecutive cases BMC Cancer 11 2011 85
    • (2011) BMC Cancer , vol.11 , pp. 85
    • Chi, Z.1    Li, S.2    Sheng, X.3
  • 28
    • 33749021085 scopus 로고    scopus 로고
    • Somatic activation of KIT in distinct subtypes of melanoma
    • J.A. Curtin, K. Busam, D. Pinkel, and B.C. Bastian Somatic activation of KIT in distinct subtypes of melanoma J Clin Oncol 24 2006 4340 4346
    • (2006) J Clin Oncol , vol.24 , pp. 4340-4346
    • Curtin, J.A.1    Busam, K.2    Pinkel, D.3    Bastian, B.C.4
  • 29
    • 79953324920 scopus 로고    scopus 로고
    • Large scale analysis of KIT aberrations in Chinese patients with melanoma
    • Y. Kong, L. Si, and Y. Zhu Large scale analysis of KIT aberrations in Chinese patients with melanoma Clin Cancer Res 17 2011 1684 1691
    • (2011) Clin Cancer Res , vol.17 , pp. 1684-1691
    • Kong, Y.1    Si, L.2    Zhu, Y.3
  • 30
    • 77956030786 scopus 로고    scopus 로고
    • Inhibition of mutated, activated BRAF in metastatic melanoma
    • K.T. Flaherty, I. Puzanov, and K.B. Kim Inhibition of mutated, activated BRAF in metastatic melanoma N Engl J Med 363 2010 809 819
    • (2010) N Engl J Med , vol.363 , pp. 809-819
    • Flaherty, K.T.1    Puzanov, I.2    Kim, K.B.3
  • 31
    • 77957350123 scopus 로고    scopus 로고
    • Phase I/II study of GSK2118436, a selective inhibitor of oncogenic mutant BRAF kinase, in patients with metastatic melanoma and other solid tumors
    • [abstr 8503]
    • R. Kefford, H. Arkenau, and M.P. Brown Phase I/II study of GSK2118436, a selective inhibitor of oncogenic mutant BRAF kinase, in patients with metastatic melanoma and other solid tumors J Clin Oncol 28 2010 [abstr 8503]
    • (2010) J Clin Oncol , vol.28
    • Kefford, R.1    Arkenau, H.2    Brown, M.P.3
  • 32
    • 79953891558 scopus 로고    scopus 로고
    • Phase 1/2 study of GSK2118436, a selective inhibitor of V600 mutant (Mut) BRAF kinase: Evidence of activity in melanoma brain metastases (Mets)
    • [abstr]
    • G.V. Long, R.F. Kefford, and P.J.A. Carr Phase 1/2 study of GSK2118436, a selective inhibitor of V600 mutant (Mut) BRAF kinase: evidence of activity in melanoma brain metastases (Mets) Ann Oncol 21 2010 LBA27 [abstr]
    • (2010) Ann Oncol , vol.21 , pp. 27
    • Long, G.V.1    Kefford, R.F.2    Carr, P.J.A.3
  • 33
    • 79952601620 scopus 로고    scopus 로고
    • BRAF mutations in cutaneous melanoma are independently associated with age, anatomic site of the primary tumor, and the degree of solar elastosis at the primary tumor site
    • J. Bauer, P. Büttner, and R. Murali BRAF mutations in cutaneous melanoma are independently associated with age, anatomic site of the primary tumor, and the degree of solar elastosis at the primary tumor site Pigment Cell Melanoma Res 24 2011 345 351
    • (2011) Pigment Cell Melanoma Res , vol.24 , pp. 345-351
    • Bauer, J.1    Büttner, P.2    Murali, R.3
  • 34
    • 33746105691 scopus 로고    scopus 로고
    • Could BRAF mutations in melanocytic lesions arise from DNA damage induced by ultraviolet radiation?
    • N.E. Thomas, M. Berwick, and M. Cordeiro-Stone Could BRAF mutations in melanocytic lesions arise from DNA damage induced by ultraviolet radiation? J Invest Dermatol 126 2006 1693 1696
    • (2006) J Invest Dermatol , vol.126 , pp. 1693-1696
    • Thomas, N.E.1    Berwick, M.2    Cordeiro-Stone, M.3
  • 35
    • 38849166096 scopus 로고    scopus 로고
    • Modeling genomic diversity and tumor dependency in malignant melanoma
    • W.M. Lin, A.C. Baker, and R. Beroukhim Modeling genomic diversity and tumor dependency in malignant melanoma Cancer Res 68 2008 664 673
    • (2008) Cancer Res , vol.68 , pp. 664-673
    • Lin, W.M.1    Baker, A.C.2    Beroukhim, R.3
  • 36
    • 75549086968 scopus 로고    scopus 로고
    • Coexisting NRAS and BRAF mutations in primary familial melanomas with specific CDKN2A germline alterations
    • B. Jovanovic, S. Egyhazi, and M. Eskandarpour Coexisting NRAS and BRAF mutations in primary familial melanomas with specific CDKN2A germline alterations J Invest Dermatol 130 2010 618 620
    • (2010) J Invest Dermatol , vol.130 , pp. 618-620
    • Jovanovic, B.1    Egyhazi, S.2    Eskandarpour, M.3
  • 37
    • 79954703723 scopus 로고    scopus 로고
    • BRAF exon 15 T1799A mutation is common in melanocytic nevi, but less prevalent in cutaneous malignant melanoma, in Chinese Han
    • R.Q. Qi, L. He, and S. Zheng BRAF exon 15 T1799A mutation is common in melanocytic nevi, but less prevalent in cutaneous malignant melanoma, in Chinese Han J Invest Dermatol 131 2011 1129 1138
    • (2011) J Invest Dermatol , vol.131 , pp. 1129-1138
    • Qi, R.Q.1    He, L.2    Zheng, S.3
  • 38
    • 33748325763 scopus 로고    scopus 로고
    • Sorafenib in advanced melanoma: A Phase II randomised discontinuation trial analysis
    • T. Eisen, T. Ahmad, and K.T. Flaherty Sorafenib in advanced melanoma: a Phase II randomised discontinuation trial analysis Br J Cancer 95 2006 581 586
    • (2006) Br J Cancer , vol.95 , pp. 581-586
    • Eisen, T.1    Ahmad, T.2    Flaherty, K.T.3
  • 39
    • 0035670803 scopus 로고    scopus 로고
    • Analysis of N- and K-ras mutations in the distinctive tumor progression phases of melanoma
    • A. Demunter, M. Stas, H. Degreef, C. De Wolf-Peeters, and J.J. van den Oord Analysis of N- and K-ras mutations in the distinctive tumor progression phases of melanoma J Invest Dermatol 117 2001 1483 1489
    • (2001) J Invest Dermatol , vol.117 , pp. 1483-1489
    • Demunter, A.1    Stas, M.2    Degreef, H.3    De Wolf-Peeters, C.4    Van Den Oord, J.J.5
  • 40
    • 33746263912 scopus 로고    scopus 로고
    • BRAF and NRAS mutations in melanoma and melanocytic nevi
    • J.N. Poynter, J.T. Elder, and D.R. Fullen BRAF and NRAS mutations in melanoma and melanocytic nevi Melanoma Res 16 2006 267 273
    • (2006) Melanoma Res , vol.16 , pp. 267-273
    • Poynter, J.N.1    Elder, J.T.2    Fullen, D.R.3


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