A new drug delivery system inhibits uveitis in an animal model after cataract surgery

International Journal of Pharmaceutics

Volumn 443, Issue 1-2, 2013, Pages 254-261

  Eperon, Simone ^a   Rodriguez Aller, Marta ^b   Balaskas, Konstantinos ^a,c   Gurny, Robert ^b   Guex Crosier, Yan ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b UNIVERSITY OF GENEVA   (Switzerland)

^c MOORFIELDS EYE HOSPITAL   (United Kingdom)

Author keywords

Cyclosporine A; Ocular inflammation; Polymeric drug delivery system; Rabbit; Triamcinolone acetonide; Uveitis

Indexed keywords

CYCLOSPORIN A; PROTEIN; TRIAMCINOLONE ACETONIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; AQUEOUS HUMOR; ARTICLE; CATARACT EXTRACTION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG INHIBITION; EXPERIMENTAL RABBIT; FEMALE; INFLAMMATORY CELL; LENS IMPLANT; LENS IMPLANTATION; NONHUMAN; POLYMERIZATION; POSTOPERATIVE COMPLICATION; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; UVEITIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BIOCOMPATIBLE MATERIALS; CATARACT EXTRACTION; CYCLOSPORINE; DISEASE MODELS, ANIMAL; DRUG CARRIERS; DRUG COMBINATIONS; DRUG DELIVERY SYSTEMS; FEMALE; LACTIC ACID; LENS IMPLANTATION, INTRAOCULAR; POLYGLYCOLIC ACID; RABBITS; TRIAMCINOLONE ACETONIDE; UVEITIS;

EID: 84873991137     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.12.033     Document Type: Article

References (39)

1. A.P. Adamis, and D.T. Shima The role of vascular endothelial growth factor in ocular health and disease Retina 25 2005 111 118
2. M.T. Cahill, and G.J. Jaffe Intraocular sustained-release drug delivery in uveitis G.J. Jaffe, P. Ashton, P.A. Pearson, Intraocular Drug Delivery 2006 Taylor & Francis Group New York 265 278
3. Y.E. Choonara, V. Pillay, M.P. Danckwerts, T.R. Carmichael, and L.C. du Toit A review of implantable intravitreal drug delivery technologies for the treatment of posterior segment eye diseases J. Pharm. Sci. 99 2010 2219 2239
4. T.A. Ciulla, J.D. Walker, D.S. Fong, and M.H. Criswell Corticosteroids in posterior segment disease: an update on new delivery systems and new indications Curr. Opin. Ophthalmol. 15 2004 211 220
5. G. Deray, M. Benhmida, H.P. Le, P. Maksud, B. Aupetit, A. Baumelou, and C. Jacobs Renal function and blood pressure in patients receiving long-term, low-dose cyclosporine therapy for idiopathic autoimmune uveitis Ann. Intern. Med. 117 1992 578 583
6. Eperon, S., Balaskas, K., Vaudaux, J.D., Guex-Crosier, Y. Experimental uveitis can be maintained in rabbits for a period of six weeks after a safe sensitization method. Curr. Eye Res., http://dx.doi.org/10.3109/02713683.2012. 747616, in press.
7. S. Eperon, L. Bossy-Nobs, I.K. Petropoulos, R. Gurny, and Y. Guex-Crosier A biodegradable drug delivery systems for the treatment of post-operative inflammation Int. J. Pharm. 352 2008 240 247
8. J.C. Erie, K.H. Baratz, D.O. Hodge, C.D. Schleck, and J.P. Burke Incidence of cataract surgery from 1980 through 2004: 25-year population-based study J. Cataract Refract. Surg. 33 2007 1273 1277
9. O. Felt-Baeyens, S. Eperon, P. Mora, Y. Guex-Crosier, S. Sagodira, P. Breton, and R. Gurny Scleral implants-A potential route of administration? Monduzzi Proceedings of the 5th International Symposium of Ocular Pharmacology and Therapeutics Monaco, France, 11-14 March, Medimond S.r.l., Pianoro (Bologna), Italy 2004 41 46
10. O. Felt-Baeyens, S. Eperon, P. Mora, D. Limal, S. Sagodira, P. Breton, B. Simonazzi, L. Bossy-Nobs, Y. Guex-Crosier, and R. Gurny Biodegradable scleral implants as new triamcinolone acetonide delivery systems Int. J. Pharm. 322 2006 6 12
11. S. Garty, R. Shirakawa, A. Warsen, E.M. Anderson, M.L. Noble, J.D. Bryers, B.D. Ratner, and T.T. Shen Sustained antibiotic release from an intraocular lens-hydrogel assembly for cataract surgery Invest. Ophthalmol. Vis. Sci. 52 2011 6109 6116
12. C.R. Ghosn, Y. Li, W.C. Orilla, T. Lin, L. Wheeler, J.A. Burke, M.R. Robinson, and S.M. Whitcup Treatment of experimental anterior and intermediate uveitis by a dexamethasone intravitreal implant Invest. Ophthalmol. Vis. Sci. 52 2011 2917 2923
13. B.C. Gilger, E. Malok, T. Stewart, D. Horohov, P. Ashton, T. Smith, G.J. Jaffe, and J.B. Allen Effect of an intravitreal cyclosporine implant on experimental uveitis in horses Vet. Immunol. Immunopathol. 76 2000 239 255
14. S.-E. Hankinson Epidemiology of age-related cataract D.M. Albert, F.A. Jakobiec, D.T. Azar, E.S. Gragoudas, Principles and Practice of Ophthalmology, Vol. 1 2000 W. B. Saunders Company Philadelphia 511 521
15. P.L. Hooper, N.A. Rao, and R.E. Smith Cataract extraction in uveitis patients Surv. Ophthalmol. 35 1990 120 144
16. G.J. Jaffe, C.S. Yang, X.C. Wang, S.W. Cousins, R.P. Gallemore, and P. Ashton Intravitreal sustained-release cyclosporine in the treatment of experimental uveitis Ophthalmology 105 1998 46 56
17. K.G. Janoria, S. Gunda, S.H. Boddu, and A.K. Mitra Novel approaches to retinal drug delivery Expert. Opin. Drug Deliv. 4 2007 371 388
18. J.B. Jonas, R.F. Degenring, I. Kreissig, I. Akkoyun, and B.A. Kamppeter Intraocular pressure elevation after intravitreal triamcinolone acetonide injection Ophthalmology 112 2005 593 598
19. R.L. Kaswan Intraocular penetration of topically applied cyclosporine Transplant Proc. 20 1988 650 655
20. N. Kuno, and S. Fujii Biodegradable intraocular therapies for retinal disorders: progress to date Drugs Aging 27 2010 117 134
21. S.Y. Lee, S.P. Chee, V. Balakrishnan, S. Farzavandi, and D.T. Tan Surodex in paediatric cataract surgery Br. J. Ophthalmol. 87 2003 1424 1426
22. C. Lowder, R. Belfort Jr., S. Lightman, C.S. Foster, M.R. Robinson, R.M. Schiffman, X.Y. Li, H. Cui, and S.M. Whitcup Dexamethasone intravitreal implant for noninfectious intermediate or posterior uveitis Arch. Ophthalmol. 129 2011 545 553
23. M. Nagpal, K. Nagpal, and P.N. Nagpal Postcataract cystoid macular edema Ophthalmol. Clin. North Am. 14 2001 651 659
24. R.B. Nussenblatt, A.G. Palestine, and C.C. Chan Cyclosporin A therapy in the treatment of intraocular inflammatory disease resistant to systemic corticosteroids and cytotoxic agents Am. J. Ophthalmol. 96 1983 275 282
25. R.B. Nussenblatt, A.G. Palestine, and C.C. Chan Cyclosporine therapy for uveitis: long-term followup J. Ocul. Pharmacol. 1 1985 369 382
26. O. Pillai, and R. Panchagnula Polymers in drug delivery Curr. Opin. Chem. Biol. 5 2001 447 451
27. M. Rodriguez-Aller, B. Kaufmann, D. Guillarme, C. Stella, P. Furrer, S. Rudaz, Z.I. El, F. Valamanesh, T.C. Di, F. Behar-Cohen, J.L. Veuthey, and R. Gurny In vivo characterisation of a novel water-soluble cyclosporine A prodrug for the treatment of dry eye disease Eur. J. Pharm. Biopharm. 80 2012 544 552
28. E. Sakurai, M. Nozaki, K. Okabe, N. Kunou, H. Kimura, and Y. Ogura Scleral plug of biodegradable polymers containing tacrolimus (FK506) for experimental uveitis Invest. Ophthalmol. Vis. Sci. 44 2003 4845 4852
29. A. Sallam, S.R. Taylor, and S. Lightman Review and update of intraocular therapy in noninfectious uveitis Curr. Opin. Ophthalmol. 22 2011 517 522
30. S.S. Siddique, R. Shah, A.M. Suelves, and C.S. Foster Road to remission: a comprehensive review of therapy in uveitis Expert Opin. Investig. Drugs 20 2011 1497 1515
31. J.N. Simone, and M.M. Whitacre Effects of anti-inflammatory drugs following cataract extraction Curr. Opin. Ophthalmol. 12 2001 63 67
32. M. Takeuchi, T. Iwasaki, T. Kezuka, Y. Usui, Y. Okunuki, J. Sakai, and H. Goto Functional and morphological changes in the eyes of Behcet's patients with uveitis Acta Ophthalmol. 88 2010 257 262
33. D.T. Tan, S.P. Chee, L. Lim, J. Theng, and M. Van Ede Randomized clinical trial of Surodex steroid drug delivery system for cataract surgery: anterior versus posterior placement of two Surodex in the eye Ophthalmology 108 2001 2172 2181
34. P. Taravati, D.L. Lam, T. Leveque, and R.N. Van Gelder Postcataract surgical inflammation Curr. Opin. Ophthalmol. 23 2012 12 18
35. J.T. Theng, S.E. Ti, L. Zhou, K.W. Lam, S.P. Chee, and D. Tan Pharmacokinetic and toxicity study of an intraocular cyclosporine DDS in the anterior segment of rabbit eyes Invest. Ophthalmol. Vis. Sci. 44 2003 4895 4899
36. H.M. Towler, P.H. Whiting, and J.V. Forrester Combination low dose cyclosporin A and steroid therapy in chronic intraocular inflammation Eye (Lond) 4 Pt 3 1990 514 520
37. A.C. Wadood, A.M. Armbrecht, P.A. Aspinall, and B. Dhillon Safety and efficacy of a dexamethasone anterior segment drug delivery system in patients after phacoemulsification J. Cataract Refract. Surg. 30 2004 761 768
38. S.M. Whitcup, E.C. Salvo Jr., and R.B. Nussenblatt Combined cyclosporine and corticosteroid therapy for sight-threatening uveitis in Behcet's disease Am. J. Ophthalmol. 118 1994 39 45
39. T. Yasukawa, Y. Ogura, E. Sakurai, Y. Tabata, and H. Kimura Intraocular sustained drug delivery using implantable polymeric devices Adv. Drug Deliv. Rev. 57 2005 2033 2046