메뉴 건너뛰기




Volumn 319, Issue 5, 2013, Pages 740-749

Nm23-H1 is a negative regulator of TGF-Β1-dependent induction of epithelial-mesenchymal transition

Author keywords

Epithelial mesenchymal transition; Lung cancer metastasis; Metastasis suppressor; Src kinase; Transforming growth factor

Indexed keywords

BETA CATENIN; FIBRONECTIN; NUCLEOSIDE DIPHOSPHATE KINASE A; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR SNAIL; TRANSFORMING GROWTH FACTOR BETA1; UVOMORULIN;

EID: 84873991064     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2012.10.013     Document Type: Article
Times cited : (27)

References (29)
  • 1
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • Thiery J.P., Sleeman J.P. Complex networks orchestrate epithelial-mesenchymal transitions. Nat. Rev. Mol. Cell Biol. 2006, 7:131-142.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 2
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
    • Polyak K., Weinberg R.A. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat. Rev. Cancer 2009, 9:265-273.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 3
    • 47549090432 scopus 로고    scopus 로고
    • TGFbeta in Cancer
    • Massague J. TGFbeta in Cancer. Cell 2008, 134:215-230.
    • (2008) Cell , vol.134 , pp. 215-230
    • Massague, J.1
  • 4
    • 24644480749 scopus 로고    scopus 로고
    • Molecular requirements for epithelial-mesenchymal transition during tumor progression
    • Huber M.A., Kraut N., Beug H. Molecular requirements for epithelial-mesenchymal transition during tumor progression. Curr. Opin. Cell Biol. 2005, 17:548-558.
    • (2005) Curr. Opin. Cell Biol. , vol.17 , pp. 548-558
    • Huber, M.A.1    Kraut, N.2    Beug, H.3
  • 5
    • 78649755556 scopus 로고    scopus 로고
    • IKK(alpha) controls canonical TGF(ss)-SMAD signaling to regulate genes expressing SNAIL and SLUG during EMT in panc1 cells
    • Brandl M., Seidler B., Haller F., Adamski J., Schmid R.M., Saur D., Schneider G. IKK(alpha) controls canonical TGF(ss)-SMAD signaling to regulate genes expressing SNAIL and SLUG during EMT in panc1 cells. J. Cell Sci. 2010, 123:4231-4239.
    • (2010) J. Cell Sci. , vol.123 , pp. 4231-4239
    • Brandl, M.1    Seidler, B.2    Haller, F.3    Adamski, J.4    Schmid, R.M.5    Saur, D.6    Schneider, G.7
  • 7
    • 0043172396 scopus 로고    scopus 로고
    • Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis
    • Grunert S., Jechlinger M., Beug H. Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis. Nat. Rev. Mol. Cell Biol. 2003, 4:657-665.
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , pp. 657-665
    • Grunert, S.1    Jechlinger, M.2    Beug, H.3
  • 9
    • 0025753514 scopus 로고
    • Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23-transfected melanoma cells
    • Leone A., Flatow U., King C.R., Sandeen M.A., Margulies I.M., Liotta L.A., Steeg P.S. Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23-transfected melanoma cells. Cell 1991, 65:25-35.
    • (1991) Cell , vol.65 , pp. 25-35
    • Leone, A.1    Flatow, U.2    King, C.R.3    Sandeen, M.A.4    Margulies, I.M.5    Liotta, L.A.6    Steeg, P.S.7
  • 10
    • 0028948137 scopus 로고
    • Effects of cytokine-mediated modulation of nm23 expression on the invasion and metastatic behavior of B16F10 melanoma cells
    • Parhar R.S., Shi Y., Zou M., Farid N.R., Ernst P., al-Sedairy S.T. Effects of cytokine-mediated modulation of nm23 expression on the invasion and metastatic behavior of B16F10 melanoma cells. Int. J. Cancer 1995, 60:204-210.
    • (1995) Int. J. Cancer , vol.60 , pp. 204-210
    • Parhar, R.S.1    Shi, Y.2    Zou, M.3    Farid, N.R.4    Ernst, P.5    al-Sedairy, S.T.6
  • 11
    • 0347382319 scopus 로고    scopus 로고
    • Nm23-H1 reduces in vitro cell migration and the liver metastatic potential of colon cancer cells by regulating myosin light chain phosphorylation
    • Suzuki E., Ota T., Tsukuda K., Okita A., Matsuoka K., Murakami M., Doihara H., Shimizu N. nm23-H1 reduces in vitro cell migration and the liver metastatic potential of colon cancer cells by regulating myosin light chain phosphorylation. Int. J. Cancer 2004, 108:207-211.
    • (2004) Int. J. Cancer , vol.108 , pp. 207-211
    • Suzuki, E.1    Ota, T.2    Tsukuda, K.3    Okita, A.4    Matsuoka, K.5    Murakami, M.6    Doihara, H.7    Shimizu, N.8
  • 12
  • 13
    • 18744421905 scopus 로고    scopus 로고
    • Overexpression of nm23-H2/NDP kinase B in a human oral squamous cell carcinoma cell line results in reduced metastasis, differentiated phenotype in the metastatic site, and growth factor-independent proliferative activity in culture
    • Miyazaki H., Fukuda M., Ishijima Y., Takagi Y., Iimura T., Negishi A., Hirayama R., Ishikawa N., Amagasa T., Kimura N. Overexpression of nm23-H2/NDP kinase B in a human oral squamous cell carcinoma cell line results in reduced metastasis, differentiated phenotype in the metastatic site, and growth factor-independent proliferative activity in culture. Clin. Cancer Res. 1999, 5:4301-4307.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 4301-4307
    • Miyazaki, H.1    Fukuda, M.2    Ishijima, Y.3    Takagi, Y.4    Iimura, T.5    Negishi, A.6    Hirayama, R.7    Ishikawa, N.8    Amagasa, T.9    Kimura, N.10
  • 14
    • 34249674439 scopus 로고    scopus 로고
    • NM23-H1 tumor suppressor physically interacts with serine-threonine kinase receptor-associated protein, a transforming growth factor-beta (TGF-beta) receptor-interacting protein, and negatively regulates TGF-beta signaling
    • Seong H.A., Jung H., Ha H. NM23-H1 tumor suppressor physically interacts with serine-threonine kinase receptor-associated protein, a transforming growth factor-beta (TGF-beta) receptor-interacting protein, and negatively regulates TGF-beta signaling. J. Biol. Chem. 2007, 282:12075-12096.
    • (2007) J. Biol. Chem. , vol.282 , pp. 12075-12096
    • Seong, H.A.1    Jung, H.2    Ha, H.3
  • 15
    • 26244458018 scopus 로고    scopus 로고
    • TGF-beta1 induces human alveolar epithelial to mesenchymal cell transition (EMT)
    • Kasai H., Allen J.T., Mason R.M., Kamimura T., Zhang Z. TGF-beta1 induces human alveolar epithelial to mesenchymal cell transition (EMT). Respir. Res. 2005, 6:56.
    • (2005) Respir. Res. , vol.6 , pp. 56
    • Kasai, H.1    Allen, J.T.2    Mason, R.M.3    Kamimura, T.4    Zhang, Z.5
  • 16
    • 0023797049 scopus 로고
    • Altered expression of NM23, a gene associated with low tumor metastatic potential, during adenovirus 2 Ela inhibition of experimental metastasis
    • Steeg P.S., Bevilacqua G., Pozzatti R., Liotta L.A., Sobel M.E. Altered expression of NM23, a gene associated with low tumor metastatic potential, during adenovirus 2 Ela inhibition of experimental metastasis. Cancer Res. 1988, 48:6550-6554.
    • (1988) Cancer Res. , vol.48 , pp. 6550-6554
    • Steeg, P.S.1    Bevilacqua, G.2    Pozzatti, R.3    Liotta, L.A.4    Sobel, M.E.5
  • 17
    • 0033795962 scopus 로고    scopus 로고
    • Nm23/nucleoside diphosphate kinase in human cancers
    • Hartsough M.T., Steeg P.S. Nm23/nucleoside diphosphate kinase in human cancers. J. Bioenerg. Biomembr. 2000, 32:301-308.
    • (2000) J. Bioenerg. Biomembr. , vol.32 , pp. 301-308
    • Hartsough, M.T.1    Steeg, P.S.2
  • 18
    • 0027304816 scopus 로고
    • Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: effects on tumor metastatic potential, colonization and enzymatic activity
    • Leone A., Flatow U., VanHoutte K., Steeg P.S. Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: effects on tumor metastatic potential, colonization and enzymatic activity. Oncogene 1993, 8:2325-2333.
    • (1993) Oncogene , vol.8 , pp. 2325-2333
    • Leone, A.1    Flatow, U.2    VanHoutte, K.3    Steeg, P.S.4
  • 19
    • 0036203835 scopus 로고    scopus 로고
    • Transfection of the nm23-H1 gene into human hepatocarcinoma cell line inhibits the expression of sialyl Lewis X, alpha1,3 fucosyltransferase VII, and metastatic potential
    • Liu F., Zhang Y., Zhang X.Y., Chen H.L. Transfection of the nm23-H1 gene into human hepatocarcinoma cell line inhibits the expression of sialyl Lewis X, alpha1,3 fucosyltransferase VII, and metastatic potential. J. Cancer Res. Clin. Oncol. 2002, 128:189-196.
    • (2002) J. Cancer Res. Clin. Oncol. , vol.128 , pp. 189-196
    • Liu, F.1    Zhang, Y.2    Zhang, X.Y.3    Chen, H.L.4
  • 21
    • 0037428893 scopus 로고    scopus 로고
    • Histidine kinases and histidine phosphorylated proteins in mammalian cell biology, signal transduction and cancer
    • Steeg P.S., Palmieri D., Ouatas T., Salerno M. Histidine kinases and histidine phosphorylated proteins in mammalian cell biology, signal transduction and cancer. Cancer Lett. 2003, 190:1-12.
    • (2003) Cancer Lett. , vol.190 , pp. 1-12
    • Steeg, P.S.1    Palmieri, D.2    Ouatas, T.3    Salerno, M.4
  • 22
    • 78349280274 scopus 로고    scopus 로고
    • Metastasis suppressor function of NM23-H1 requires its 3'-5' exonuclease activity
    • Zhang Q., McCorkle J.R., Novak M., Yang M., Kaetzel D.M. Metastasis suppressor function of NM23-H1 requires its 3'-5' exonuclease activity. Int. J. Cancer 2011, 128:40-50.
    • (2011) Int. J. Cancer , vol.128 , pp. 40-50
    • Zhang, Q.1    McCorkle, J.R.2    Novak, M.3    Yang, M.4    Kaetzel, D.M.5
  • 24
    • 41949105179 scopus 로고    scopus 로고
    • Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling
    • Wu X., Tu X., Joeng K.S., Hilton M.J., Williams D.A., Long F. Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling. Cell 2008, 133:340-353.
    • (2008) Cell , vol.133 , pp. 340-353
    • Wu, X.1    Tu, X.2    Joeng, K.S.3    Hilton, M.J.4    Williams, D.A.5    Long, F.6
  • 25
    • 60849098434 scopus 로고    scopus 로고
    • Integrin alpha3beta1-dependent beta-catenin phosphorylation links epithelial Smad signaling to cell contacts
    • Kim Y., Kugler M.C., Wei Y., Kim K.K., Li X., Brumwell A.N., Chapman H.A. Integrin alpha3beta1-dependent beta-catenin phosphorylation links epithelial Smad signaling to cell contacts. J. Cell Biol. 2009, 184:309-322.
    • (2009) J. Cell Biol. , vol.184 , pp. 309-322
    • Kim, Y.1    Kugler, M.C.2    Wei, Y.3    Kim, K.K.4    Li, X.5    Brumwell, A.N.6    Chapman, H.A.7
  • 27
    • 43749094970 scopus 로고    scopus 로고
    • Alteration in gene expression profile and biological behavior in human lung cancer cell line NL9980 by nm23-H1 gene silencing
    • Ma W., Chen J., Xue X., Wang Z., Liu H., Wang T., Bai Y., Tang S.C., Zhou Q. Alteration in gene expression profile and biological behavior in human lung cancer cell line NL9980 by nm23-H1 gene silencing. Biochem. Biophys. Res. Commun. 2008, 371:425-430.
    • (2008) Biochem. Biophys. Res. Commun. , vol.371 , pp. 425-430
    • Ma, W.1    Chen, J.2    Xue, X.3    Wang, Z.4    Liu, H.5    Wang, T.6    Bai, Y.7    Tang, S.C.8    Zhou, Q.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.