Functional compensation between cholecystokinin-1 and -2 receptors in murine paraventricular nucleus neurons

Journal of Biological Chemistry

Volumn 287, Issue 47, 2012, Pages 39391-39401

  Mohammad, Shahid ^a   Ozaki, Tomoya ^a   Takeuchi, Kouhei ^a   Unno, Katsuya ^a   Yamoto, Kurumi ^a   Morioka, Eri ^a   Takiguchi, Soichi ^b   Ikeda, Masayuki ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b NATIONAL KYUSHU CANCER CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGY;

CONTROLLING MECHANISM; KNOCK OUTS; PARAVENTRICULAR NUCLEUS; RECEPTOR GENES; RECEPTOR LIGANDS; RECEPTOR SIGNALING;

GENES;

4 [[2 [2 [[(2 ADAMANTYLOXY)CARBONYL]AMINO] 3 (1H INDOL 3 YL) 2 METHYLPROPIONAMIDO] 1 PHENYLETHYL]AMINO] 4 OXOBUTYRIC ACID MEGLUMINE; CALCIUM; CHOLECYSTOKININ A RECEPTOR; CHOLECYSTOKININ B RECEPTOR; CHOLECYSTOKININ OCTAPEPTIDE; LORGLUMIDE; 8 SULFOCHOLECYSTOKININ OCTAPEPTIDE; 8-SULFOCHOLECYSTOKININ OCTAPEPTIDE; CCK1 PROTEIN, MOUSE; CHOLECYSTOKININ RECEPTOR; DRUG DERIVATIVE; NERVE PROTEIN; NOOTROPIC AGENT;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CALCIUM SIGNALING; CONTROLLED STUDY; FOOD INTAKE; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; IMMUNOFLUORESCENCE; MALE; MOUSE; NONHUMAN; PARVOCELLULAR PARAVENTRICULAR NUCLEUS CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; SATIETY RESPONSE; UPREGULATION; WESTERN BLOTTING; ANIMAL; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; GENETICS; METABOLISM; MOUSE MUTANT; NERVE CELL; PHYSIOLOGY;

ANIMALS; CALCIUM; CALCIUM SIGNALING; DOSE-RESPONSE RELATIONSHIP, DRUG; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; NEURONS; NOOTROPIC AGENTS; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; RECEPTOR, CHOLECYSTOKININ B; RECEPTORS, CHOLECYSTOKININ; SINCALIDE;

EID: 84873979498     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.416214     Document Type: Article

References (50)

1. Ivy, A. C., and Oldberg, E. (1928) A hormone mechanism for gallbladder contraction and evacuation. Am. J. Physiol. 86, 599-613
2. Rinaman, L., Verbalis, J. G., Stricker, E. M., and Hoffman, G. E. (1993) Distribution and neurochemical phenotypes of caudal medullary neurons activated to express cFos following peripheral administration of cholecystokinin. J. Comp. Neurol. 338, 475-490
3. Mönnikes, H., Lauer, G., Bauer, C., Tebbe, J., Zittel, T. T., and Arnold, R. (1997) Pathways of Fos expression in locus ceruleus, dorsal vagal complex, and PVN in response to intestinal lipid. Am. J. Physiol. Regul. Integr. Comp. Physiol. 273, R2059-R2071
4. Reidelberger, R. D., Hernandez, J., Fritzsch, B., and Hulce, M. (2004) Abdominal vagal mediation of the satiety effects of CCK in rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 286, R1005-R1012
5. Bi, S., Scott, K. A., Kopin, A. S., and Moran, T. H. (2004) Differential roles for cholecystokinin a receptors in energy balance in rats and mice. Endocrinology 145, 3873-3880
6. Honda, T., Wada, E., Battey, J. F., and Wank, S. A. (1993) Differential gene expression of CCK(A) and CCK(B) receptors in the rat brain. Mol. Cell. Neurosci. 4, 143-154
7. Shimazoe, T., Morita, M., Ogiwara, S., Kojiya, T., Goto, J., Kamakura, M., Moriya, T., Shinohara, K., Takiguchi, S., Kono, A., Miyasaka, K., Funakoshi, A., and Ikeda, M. (2008) Cholecystokinin-A receptors regulate photic input pathways to the circadian clock. FASEB J. 22, 1479-1490
8. Moran, T. H., Ameglio, P. J., Schwartz, G. J., and McHugh, P. R. (1992) Blockade of type A, not type B, CCK receptors attenuates satiety actions of exogenous and endogenous CCK. Am. J. Physiol. 262, R46-R50
9. Simmons, R. D., Kaiser, F. C., and Hudzik, T. J. (1999) Behavioral effects of AR-R 15849, a highly selective CCK-A agonist. Pharmacol. Biochem. Behav. 62, 549-557
10. Takiguchi, S., Takata, Y., Funakoshi, A., Miyasaka, K., Kataoka, K., Fujimura, Y., Goto, T., and Kono, A. (1997) Disrupted cholecystokinin type-A receptor (CCKAR) gene in OLETF rats. Gene 197, 169-175
11. Moran, T. H., Katz, L. F., Plata-Salaman, C. R., and Schwartz, G. J. (1998) Disordered food intake and obesity in rats lacking cholecystokinin A receptors. Am. J. Physiol. Regul. Integr. Comp. Physiol. 274, R618-R625
12. Berna, M. J., Tapia, J. A., Sancho, V., and Jensen, R. T. (2007) Progress in developing cholecystokinin (CCK)/gastrin receptor ligands that have therapeutic potential. Curr. Opin. Pharmacol. 7, 583-592
13. Raboin, S. J., Reeve, J. R., Jr., Cooper, M. S., Green, G. M., and Sayegh, A. I. (2008) Activation of submucosal but not myenteric plexus of the gastrointestinal tract accompanies reduction of food intake by camostat. Regul. Pept. 150, 73-80
14. Washington, M. C., Murry, C. R., Raboin, S. J., Roberson, A. E., Mansour, M. M., Williams, C. S., and Sayegh, A. I. (2011) Cholecystokinin-8 activates myenteric neurons in 21- and 35-day old but not 4- and 14-day-old rats. Peptides 32, 272-280
15. Smith, G. P., Jerome, C., Cushin, B. J., Eterno, R., and Simansky, K. J. (1981) Abdominal vagotomy blocks the satiety effect of cholecystokinin in the rat. Science 213, 1036-1037
16. Broberger, C., Holmberg, K., Shi, T. J., Dockray, G., and Hökfelt, T. (2001) Expression and regulation of cholecystokinin and cholecystokinin receptors in rat nodose and dorsal root ganglia. Brain Res. 903, 128-140
17. Appleyard, S. M., Marks, D., Kobayashi, K., Okano, H., Low, M. J., and Andresen, M. C. (2007) Visceral afferents directly activate catecholamine neurons in the solitary tract nucleus. J. Neurosci. 27, 13292-13302
18. Guard, D. B., Swartz, T. D., Ritter, R. C., Burns, G. A., and Covasa, M. (2009) NMDA NR2 receptors participate in CCK-induced reduction of food intake and hindbrain neuronal activation. Brain Res. 1266, 37-44
19. Hinks, G. L., Poat, J. A., and Hughes, J. (1995) Changes in hypothalamic cholecystokininAand cholecystokinin B receptor subtypes and associated neuropeptide expression in response to salt-stress in the rat and mouse. Neuroscience 68, 765-781
20. van den Pol, A. N., and Tsujimoto, K. L. (1985) Neurotransmitters of the hypothalamic suprachiasmatic nucleus. Immunocytochemical analysis of 25 neuronal antigens. Neuroscience 15, 1049-1086
21. Aston-Jones, G., Chen, S., Zhu, Y., and Oshinsky, M. L. (2001) A neural circuit for circadian regulation of arousal. Nat. Neurosci. 4, 732-738
22. Crawley, J. N., Fiske, S. M., Durieux, C., Derrien, M., and Roques, B. P. (1991) Centrally administered cholecystokinin suppresses feeding through a peripheral-type receptor mechanism. J. Pharmacol. Exp. Ther. 257, 1076-1080
23. Hirosue, Y., Inui, A., Teranishi, A., Miura, M., Nakajima, M., Okita, M., Nakajima, Y., Himori, N., Baba, S., Kasuga, M. (1993) Cholecystokinin octapeptide analogues suppress food intake via central CCK-A receptors in mice. Am. J. Physiol. 265, R481-R486
24. Uchoa, E. T., Mendes da Silva, L. E., de Castro, M., Antunes-Rodrigues, J., and Elias, L. L. (2009) Hypothalamic oxytocin neurons modulate hypo-phagic effect induced by adrenalectomy. Horm. Behav. 56, 532-538
25. Panicker, A. K., Mangels, R. A., Powers, J. B., Wade, G. N., and Schneider, J. E. (1998) AP lesions block suppression of estrous behavior, but not estrous cyclicity, in food-deprived Syrian hamsters. Am. J. Physiol. 275, R158-R164
26. Kopin, A. S., Mathes, W. F., McBride, E. W., Nguyen, M., Al-Haider, W., Schmitz, F., Bonner-Weir, S., Kanarek, R., and Beinborn, M. (1999) The cholecystokinin-A receptor mediates inhibition of food intake yet is not essential for the maintenance of body weight. J. Clin. Invest. 103, 383-391
27. Takiguchi, S., Suzuki, S., Sato, Y., Kanai, S., Miyasaka, K., Jimi, A., Shinozaki, H., Takata, Y., Funakoshi, A., Kono, A., Minowa, O., Kobayashi, T., and Noda, T. (2002) Role of CCK-A receptor for pancreatic function in mice. A study in CCK-A receptor knockout mice. Pancreas 24, 276-283
28. Ikeda, M., Sugiyama, T., Wallace, C. S., Gompf, H. S., Yoshioka, T., Miyawaki, A., and Allen, C. N. (2003) Circadian dynamics of cytosolic and nuclear Ca2+ in single suprachiasmatic nucleus neurons. Neuron 38, 253-263
29. Ikeda, M., Yoshioka, T., and Allen, C. N. (2003) Developmental and circadian changes in Ca2+ mobilization mediated by GABAA and NMDA receptors in the suprachiasmatic nucleus. Eur. J. Neurosci. 17, 58-70
30. Swanson, L. W., and Sawchenko, P. E. (1980) Paraventricular nucleus. A site for the integration of neuroendocrine and autonomic mechanisms. Neuroendocrinology 31, 410-417
31. Swanson, L. W., Kuypers, H. G. (1980) The paraventricular nucleus of the hypothalamus. Cytoarchitectonic subdivisions and organization of projections to the pituitary, dorsal vagal complex, and spinal cord as demonstrated by retrograde fluorescence double-labeling methods. J. Comp. Neurol. 194, 555-570
32. Swanson, L. W., and Sawchenko, P. E. (1983) Hypothalamic integration. Organization of the paraventricular and supraoptic nuclei. Annu. Rev. Neurosci. 6, 269-324
33. Stern, J. E. (2001) Electrophysiological and morphological properties of pre-autonomic neurones in the rat hypothalamic paraventricular nucleus. J. Physiol. 537, 161-177
34. Koutcherov, Y., Mai, J. K., Ashwell, K. W., and Paxinos, G. (2000) Organization of the human paraventricular hypothalamic nucleus. J. Comp. Neurol. 423, 299-318
35. Hashimoto, H., Onaka, T., Kawasaki, M., Chen, L., Mera, T., Soya, A., Saito, T., Fujihara, H., Sei, H., Morita, Y., and Ueta, Y. (2005) Effects of cholecystokinin (CCK)-8 on hypothalamic oxytocin-secreting neurons in rats lacking CCK-A receptor. Auton. Neurosci. 121, 16-25
36. Sorimachi, M., Yamagami, K., and Uramura, K. (2001) Functional expression of cholecystokinin-A receptor on ventromedial hypothalamic neurons in the immature rat brain. Neurosci. Lett. 300, 91-94
37. Kopin, A. S., Lee, Y. M., McBride, E. W., Miller, L. J., Lu, M., Lin, H. Y., Kolakowski, L. F., Jr., and Beinborn, M. (1992) Expression cloning and characterization of the canine parietal cell gastrin receptor. Proc. Natl. Acad. Sci. U.S.A. 89, 3605-3609
38. Ulrich, C. D., Ferber, I., Holicky, E., Hadac, E., Buell, G., and Miller, L. J. (1993) Molecular cloning and functional expression of the human gallbladder cholecystokinin A receptor. Biochem. Biophys. Res. Commun. 193, 204-211
39. Cheng, Z. J., Harikumar, K. G., Holicky, E. L., and Miller, L. J. (2003) Heterodimerization of type A and B cholecystokinin receptors enhance signaling and promote cell growth. J. Biol. Chem. 278, 52972-52979
40. Gibbs, J., Young, R. C., and Smith, G. P. (1973) Cholecystokinin elicits satiety in rats with open gastric fistulas. Nature 245, 323-325
41. Wank, S. A., Harkins, R., Jensen, R. T., Shapira, H., de Weerth, A., and Slattery, T. (1992) Purification, molecular cloning, and functional expression of the cholecystokinin receptor from rat pancreas. Proc. Natl. Acad. Sci. U.S.A. 89, 3125-3129
42. Wank, S. A., Pisegna, J. R., and de Weerth, A. (1992) Brain and gastrointestinal cholecystokinin receptor family. Structure and functional expression. Proc. Natl. Acad. Sci. U.S.A. 89, 8691-8695
43. Mönnikes, H., Tebbe, J., Grote, C., Sonntag, A., Pluntke, K., Sturm, K., and Arnold, R. (2000) Involvement of CCK in the paraventricular nucleus of the hypothalamus in the CNS regulation of colonic motility. Digestion 62, 178-184
44. Yang, L., Scott, K. A., Hyun, J., Tamashiro, K. L., Tray, N., Moran, T. H., and Bi, S. (2009) Role of dorsomedial hypothalamic neuropeptide Y in modulating food intake and energy balance. J. Neurosci. 29, 179-190
45. Blevins, J. E., Overduin, J., Fuller, J. M., Cummings, D. E., Matsumoto, K., and Moralejo, D. H. (2009) Normal feeding and body weight in Fischer 344 rats lacking the cholecystokinin-1 receptor gene. Brain Res. 1255, 98-112
46. Muramatsu, Y., Yamada, T., Taniguchi, Y., Ogino, T., Kose, H., Matsumoto, K., Sasaki, Y. (2005) Pnlip encoding pancreatic lipase is possible candidate for obesity QTL in the OLETF rat. Biochem. Biophys. Res. Commun. 331, 1270-1276
47. Ozaki, T., Mohammad, S., Morioka E., Takiguchi, S., and Ikeda, M. (2011) Infant saiety depends on ependymal cholecystokinin-1 receptors. Soc. Neurosci. Abstr. 192.15
48. Lo, C. M., Samuelson, L. C., Chambers, J. B., King, A., Heiman, J., Jandacek, R. J., Sakai, R. R., Benoit, S. C., Raybould, H. E., Woods, S. C., and Tso, P. (2008) Characterization of mice lacking the gene for cholecystokinin. Am. J. Physiol. Regul. Integr. Comp. Physiol. 294, R803-R810
49. Wang, L., Barachina, M. D., Martínez, V., Wei, J. Y., and Taché, Y. (2000) Synergistic interaction between CCK and leptin to regulate food intake. Regul. Pept. 92, 79-85
50. Li, Y., Wu, X., Zhou, S., and Owyang, C. (2011) Low-affinity CCK-A receptors are coexpressed with leptin receptors in rat nodose ganglia. Implications for leptin as a regulator of short-term satiety. Am. J. Physiol. Gastrointest. Liver Physiol. 300, G217-G227