Adenovirus 36, adiposity, and bone strength in late-adolescent females

Journal of Bone and Mineral Research

Volumn 28, Issue 3, 2013, Pages 489-496

  Laing, Emma M ^a   Tripp, Ralph A ^b   Pollock, Norman K ^c   Baile, Clifton A ^a   Della Fera, Mary Anne ^b   Rayalam, Srujana ^d   Tompkins, Stephen M ^b   Keys, Deborah A ^e   Lewis, Richard D ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

^c MEDICAL COLLEGE OF GEORGIA   (United States)

^d PHILADELPHIA COLLEGE OF OSTEOPATHIC MEDICINE   (United States)

^e Independent statistical consultant   (United States)

Author keywords

ADENOVIRUS; BONE GEOMETRY; BONE STRENGTH; OBESITY; PERIPHERAL QUANTITATIVE COMPUTED TOMOGRAPHY

Indexed keywords

NEUTRALIZING ANTIBODY; VIRUS ANTIBODY;

ADENOVIRUS; ADENOVIRUS 36; ADULT; ARTICLE; BODY FAT; BONE DENSITY; BONE LENGTH; BONE MASS; BONE STRENGTH; BONE STRESS; COMPUTER ASSISTED TOMOGRAPHY; CORTICAL BONE; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; METAPHYSIS; OBESITY; QUANTITATIVE ANALYSIS; RADIUS; SKELETAL MUSCLE; TIBIA; TRABECULAR BONE;

ABSORPTIOMETRY, PHOTON; ADENOVIRIDAE; ADIPOSITY; ADOLESCENT; ADULT; BONE AND BONES; FEMALE; HUMANS; TOMOGRAPHY, X-RAY COMPUTED; YOUNG ADULT;

EID: 84873979274     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1776     Document Type: Article

References (50)

1. Atkinson RL, Dhurandhar NV, Allison DB, Bowen RL, Israel BA, Albu JB, Augustus AS., Human adenovirus-36 is associated with increased body weight and paradoxical reduction of serum lipids. Int J Obes (Lond). 2005; 29: 281-6.
2. Atkinson RL, Lee I, Shin HJ, He J., Human adenovirus-36 antibody status is associated with obesity in children. Int J Pediatr Obes. 2010; 5: 157-60.
3. Rossner S., [Can obesity be an infectious disease?]. Lakartidningen. 2005; 102: 1896-8.
4. van Ginneken V, Sitnyakowsky L, Jeffery JE., Infectobesity: viral infections (especially with human adenovirus-36: Ad-36) may be a cause of obesity. Med Hypotheses. 2009; 72: 383-8.
5. Dhurandhar NV, Kulkarni PR, Ajinkya SM, Sherikar AA, Atkinson RL., Association of adenovirus infection with human obesity. Obes Res. 1997; 5: 464-9.
6. Atkinson RL., Viruses as an etiology of obesity. Mayo Clin Proc. 2007; 82: 1192-8.
7. Gabbert C, Donohue M, Arnold J, Schwimmer JB., Adenovirus 36 and obesity in children and adolescents. Pediatrics. 2010; 126: 721-6.
8. Na HN, Hong YM, Kim J, Kim HK, Jo I, Nam JH., Association between human adenovirus-36 and lipid disorders in Korean schoolchildren. Int J Obes (Lond). 2010; 34: 89-93.
9. Atkinson RL., Human adenovirus-36 and childhood obesity. Int J Pediatr Obes. 2011; 6 (Suppl 1): 2-6.
10. Kalkwarf HJ, Laor T, Bean JA., Fracture risk in children with a forearm injury is associated with volumetric bone density and cortical area (by peripheral QCT) and areal bone density (by DXA). Osteoporos Int. 2011; 22: 607-16.
11. Gold J, Pocock N, Li Y., Bone mineral density abnormalities in patients with HIV infection. J Acquir Immune Defic Syndr. 2002; 30: 131-2.
12. Knobel H, Guelar A, Vallecillo G, Nogues X, Diez A., Osteopenia in patients HIV-infected is it the disease or is it the treatment?. AIDS. 2001; 15: 807-8.
13. Pollock NK, Laing EM, Baile CA, Hamrick MW, Hall DB, Lewis RD., Is adiposity advantageous for bone strength? A peripheral quantitative computed tomography study in late adolescent females. Am J Clin Nutr. 2007; 86: 1530-8.
14. Williams DP, Going SB, Lohman TG, Harsha DW, Srinivasan SR, Webber LS, Berenson GS., Body fatness and risk for elevated blood pressure, total cholesterol, and serum lipoprotein ratios in children and adolescents. Am J Public Health. 1992; 82: 358-63.
15. Going SB, Lohman TG, Falls HB., Body composition assessments. FitnessGram-ActivityGram reference guide 2008. [Internet]. Dallas, TX: The Cooper Institute; 2008 [cited 2012 Oct 2]. Available from; http://www. cooperinstitute.org/ourkidshealth/fitnessgram/references.cfm.
16. Pollock NK, Bernard PJ, Gutin B, Davis CL, Zhu H, Dong Y., Adolescent obesity, bone mass, and cardiometabolic risk factors. J Pediatr. 2011; 158: 727-34.
17. National Institutes of Health. Office of Extramural Research. NIH Policy and Guidelines on the Inclusion of Women and Minorities as Subjects in Clinical Research, Amended, October, 2001. Bethesda, MD: Office of Extramural Research, National Institutes of Health; 2001 [cited 2012 Oct 2]. Available from; http://grants.nih.gov/grants/funding/women-min/guidelines-amended-10-2001.htm.
18. Blair SN, Haskell WL, Ho P, Paffenbarger RSJJr, Vranizan KM, Farquhar JW, Wood PD., Assessment of habitual physical activity by a seven-day recall in a community survey and controlled experiments. Am J Epidemiol. 1985; 122: 794-804.
19. Washburn RA, Jacobsen DJ, Sonko BJ, Hill JO, Donnelly JE., The validity of the Stanford Seven-Day Physical Activity Recall in young adults. Med Sci Sports Exerc. 2003; 35: 1374-80.
20. Schiessl H, Ferretti J, Tysarczyk-Neimeyer G, Willnecker J., Paediatric osteology: new developments in diagnostics and therapy. Amsterdam: Elsevier; 1996.
21. Kontulainen SA, Johnston JD, Liu D, Leung C, Oxland TR, McKay HA., Strength indices from pQCT imaging predict up to 85% of variance in bone failure properties at tibial epiphysis and diaphysis. J Musculoskelet Neuronal Interact. 2008; 8: 401-9.
22. Schoenau E., From mechanostat theory to development of the "Functional Muscle-Bone-Unit ". J Musculoskelet Neuronal Interact. 2005; 5: 232-8.
23. Maughan RJ, Watson JS, Weir J., Strength and cross-sectional area of human skeletal muscle. J Physiol. 1983; 338: 37-49.
24. Farr JN, Funk JL, Chen Z, Lisse JR, Blew RM, Lee VR, Laudermilk M, Lohman TG, Going SB., Skeletal muscle fat content is inversely associated with bone strength in young girls. J Bone Miner Res. 2011; 26: 2217-25.
25. Rauch F, Bailey DA, Baxter-Jones A, Mirwald R, Faulkner R., The 'muscle-bone unit' during the pubertal growth spurt. Bone. 2004; 34: 771-5.
26. Trovato GM, Castro A, Tonzuso A, Garozzo A, Martines GF, Pirri C, Trovato F, Catalano D., Human obesity relationship with Ad36 adenovirus and insulin resistance. Int J Obes (Lond). 2009; 33: 1402-9.
27. Trovato GM, Martines GF, Garozzo A, Tonzuso A, Timpanaro R, Pirri C, Trovato FM, Catalano D., Ad36 adipogenic adenovirus in human non-alcoholic fatty liver disease. Liver Int. 2010; 30: 184-90.
28. Trovato GM, Martines GF, Trovato FM, Pirri C, Pace P, Garozzo A, Castro A, Catalano D., Adenovirus-36 seropositivity enhances effects of nutritional intervention on obesity, bright liver, and insulin resistance. Dig Dis Sci. 2012; 57: 535-44.
29. Rauch F, Schoenau E., The developing bone: slave or master of its cells and molecules ? Pediatr Res. 2001; 50: 309-14.
30. Frost HM., Bone "mass" and the "mechanostat": a proposal. Anat Rec. 1987; 219: 1-9.
31. Frost HM, Schonau E., The "muscle-bone unit" in children and adolescents: a. 2000 overview. J Pediatr Endocrinol Metab. 2000; 13: 571-90.
32. Musri MM, Gomis R, Parrizas M., A chromatin perspective of adipogenesis. Organogenesis. 2010; 6: 15-23.
33. Kahn CR., Medicine Can we nip obesity in its vascular bud?. Science. 2008; 322: 542-3.
34. Tang W, Zeve D, Suh JM, Bosnakovski D, Kyba M, Hammer RE, Tallquist MD, Graff JM., White fat progenitor cells reside in the adipose vasculature. Science. 2008; 322: 583-6.
35. Liel Y, Edwards J, Shary J, Spicer KM, Gordon L, Bell NH., The effects of race and body habits on bone mineral density of the radius, hip and spine in premenopausal women. J Clin Endocrinol Metab. 1988; 78: 1247-50.
36. Goulding A, Taylor RW, Jones IE, McAuley KA, Manning PJ, Williams SM., Overweight and obese children have low bone mass and area for their weight. Int J Obes Relat Metab Disord. 2000; 24: 627-32.
37. Hsu YH, Venners SA, Terwedow HA, Feng Y, Niu T, Li Z, Laird N, Brain JD, Cummings SR, Bouxsein ML, Rosen CJ, Xu X., Relation of body composition fat mass, and serum lipids to osteoporotic fractures and bone mineral density in Chinese men and women. Am J Clin Nutr. 2006; 83: 146-54.
38. Pollock NK, Laing EM, Hamrick MW, Baile CA, Hall DB, Lewis RD., Bone and fat relationships in postadolescent black females: a pQCT study. Osteoporos Int. 2011; 22: 655-65.
39. Goulding A, Jones IE, Taylor RW, Williams SM, Manning PJ., Bone mineral density and body composition in boys with distal forearm fractures: a dual-energy X-ray absorptiometry study. J Pediatr. 2001; 139: 509-15.
40. Ducher G, Bass SL, Naughton GA, Eser P, Telford RD, Daly RM., Overweight children have a greater proportion of fat mass relative to muscle mass in the upper limbs than in the lower limbs: implications for bone strength at the distal forearm. Am J Clin Nutr. 2009; 90: 1104-11.
41. Goulding A, Cannan R, Williams SM, Gold EJ, Taylor RW, Lewis-Barned NJ., Bone mineral density in girls with forearm fractures. J Bone Miner Res. 1998; 13: 143-8.
42. Skaggs DL, Loro ML, Pitukcheewanont P, Tolo V, Gilsanz V., Increased body weight and decreased radial cross-sectional dimensions in girls with forearm fractures. J Bone Miner Res. 2001; 16: 1337-42.
43. Bouwman JJ, Visseren FL, Bouter KP, Diepersloot RJ., Infection-induced inflammatory response of adipocytes in vitro. Int J Obes (Lond). 2008; 32: 892-01.
44. Pasarica M, Mashtalir N, McAllister EJ, Kilroy GE, Koska J, Permana P, de Courten B, Yu M, Ravussin E, Gimble JM, Dhurandhar NV., Adipogenic human adenovirus Ad-36 induces commitment, differentiation, and lipid accumulation in human adipose-derived stem cells. Stem Cells. 2008; 26: 969-78.
45. Vangipuram SD, Yu M, Tian J, Stanhope KL, Pasarica M, Havel PJ, Heydari AR, Dhurandhar NV., Adipogenic human adenovirus-36 reduces leptin expression and secretion and increases glucose uptake by fat cells. Int J Obes (Lond). 2007; 31: 87-96.
46. Khosla S, Riggs BL, Robb RA, Camp JJ, Achenbach SJ, Oberg AL, Rouleau PA., Melton LJ 3rd. Relationship of volumetric bone density and structural parameters at different skeletal sites to sex steroid levels in women. J Clin Endocrinol Metab. 2005; 90: 5096-103.
47. Schiessl H, Frost HM, Jee WS., Estrogen and bone-muscle strength and mass relationships. Bone. 1998; 22: 1-6.
48. Parhami F, Morrow AD, Balucan J, Leitinger N, Watson AD, Tintut Y, Berliner JA, Demer LL., Lipid oxidation products have opposite effects on calcifying vascular cell and bone cell differentiation. A possible explanation for the paradox of arterial calcification in osteoporotic patients. Arterioscler Thromb Vasc Biol. 1997; 17: 680-7.
49. Laing EM, Massoni JA, Nickols-Richardson SM, Modlesky CM, O'Connor PJ, Lewis RD., A prospective study of bone mass and body composition in female adolescent gymnasts. J Pediatr. 2002; 141: 211-6.
50. Laing EM, Wilson AR, Modlesky CM, O'Connor PJ, Hall DB, Lewis RD., Initial years of recreational artistic gymnastics training improves lumbar spine bone mineral accrual in 4- to 8-year-old females. J Bone Miner Res. 2005; 20: 509-19.