Fracture risk in children with a forearm injury is associated with volumetric bone density and cortical area (by peripheral QCT) and areal bone density (by DXA)

Osteoporosis International

Volumn 22, Issue 2, 2011, Pages 607-616

  Kalkwarf, H J ^b   Laor, T ^a   Bean, J A ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b ML 5041 ^*

Author keywords

Bone densitometry; Epidemiology; Fracture; Orthopedics; Pediatrics; QCT

Indexed keywords

ADOLESCENT; AREA UNDER THE CURVE; ARTICLE; BONE CHARACTERISTICS AND FUNCTIONS; BONE DENSITOMETRY; BONE DENSITY; BONE METABOLISM; BONE STRENGTH; CHILD; CHILDHOOD INJURY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORTICAL BONE; DISEASE ASSOCIATION; DISEASE SEVERITY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FOREARM; FOREARM FRACTURE; GEOMETRY; HIP; HUMAN; MAJOR CLINICAL STUDY; MALE; PERIPHERAL QUANTITATIVE COMPUTED TOMOGRAPHY; PRESCHOOL CHILD; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RADIUS; RECEIVER OPERATING CHARACTERISTIC; SCHOOL CHILD; SPINE; THICKNESS; TRABECULAR BONE;

ABSORPTIOMETRY, PHOTON; ADOLESCENT; BONE DENSITY; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; FEMALE; FOREARM INJURIES; HUMANS; IMAGING, THREE-DIMENSIONAL; MALE; RADIUS; RADIUS FRACTURES; RETROSPECTIVE STUDIES; TOMOGRAPHY, X-RAY COMPUTED; ULNA FRACTURES;

EID: 78651491741     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-010-1333-z     Document Type: Article

References (39)

1. IE Jones SM Williams N Dow A Goulding 2002 How many children remain fracture-free during growth? A longitudinal study of children and adolescents participating in the Dunedin Multidisciplinary Health and Development Study Osteoporos Int 13 990 995 1:STN:280:DC%2BD38npvVCitw%3D%3D 10.1007/s001980200137 12459942
2. C Cooper EM Dennison HG Leufkens N Bishop TP van Staa 2004 Epidemiology of childhood fractures in Britain: a study using the general practice research database J Bone Miner Res 19 1976 1981 10.1359/jbmr.040902 15537440
3. IE Jones R Cannan A Goulding 2000 Distal forearm fractures in New Zealand children: annual rates in a geographically defined area N Z Med J 113 443 445 1:STN:280:DC%2BD3M7gslarug%3D%3D 11194765
4. S Khosla LJ Melton 3rd MB Dekutoski SJ Achenbach AL Oberg BL Riggs 2003 Incidence of childhood distal forearm fractures over 30 years: a population-based study JAMA 290 1479 1485 1:CAS:528:DC%2BD3sXntlCmsb8%3D 10.1001/jama.290.11.1479 13129988
5. A Goulding R Cannan SM Williams EJ Gold RW Taylor NJ Lewis-Barned 1998 Bone mineral density in girls with forearm fractures J Bone Miner Res 13 143 148 1:STN:280:DyaK1c7gsVSgtQ%3D%3D 10.1359/jbmr.1998.13.1.143 9443800
6. A Goulding IE Jones RW Taylor SM Williams PJ Manning 2001 Bone mineral density and body composition in boys with distal forearm fractures: a dual-energy X-ray absorptiometry study J Pediatr 139 509 515 1:STN:280:DC%2BD3MrltFKqsA%3D%3D 10.1067/mpd.2001.116297 11598596
7. K Manias D McCabe N Bishop 2006 Fractures and recurrent fractures in children; varying effects of environmental factors as well as bone size and mass Bone 39 652 657 10.1016/j.bone.2006.03.018 16765659
8. EM Clark AR Ness JH Tobias 2008 Vigorous physical activity increases fracture risk in children irrespective of bone mass: a prospective study of the independent risk factors for fractures in healthy children J Bone Miner Res 23 1012 1022 10.1359/jbmr.080303 18570539
9. ML Bouxsein D Karasik 2006 Bone geometry and skeletal fragility Curr Osteoporos Rep 4 49 56 10.1007/s11914-006-0002-9 16822403
10. G Jones P Boon 2008 Which bone mass measures discriminate adolescents who have fractured from those who have not? Osteoporos Int 19 251 255 1:STN:280:DC%2BD1c%2Fgs1OjsA%3D%3D 10.1007/s00198-007-0458-1 17713714
11. SL Ferrari T Chevalley JP Bonjour R Rizzoli 2006 Childhood fractures are associated with decreased bone mass gain during puberty: an early marker of persistent bone fragility? J Bone Miner Res 21 501 507 10.1359/jbmr.051215 16598368
12. A Goulding AM Grant SM Williams 2005 Bone and body composition of children and adolescents with repeated forearm fractures J Bone Miner Res 20 2090 2096 10.1359/JBMR.050820 16294262
13. DL Skaggs ML Loro P Pitukcheewanont V Tolo V Gilsanz 2001 Increased body weight and decreased radial cross-sectional dimensions in girls with forearm fractures J Bone Miner Res 16 1337 1342 1:STN:280:DC%2BD38%2FhvVChsw%3D%3D 10.1359/jbmr.2001.16.7.1337 11450710
14. S Cheng L Xu PHF Nicholson FA Tylavsky A Lyytikainen Q Wang H Suominen UM Kujala H Kroger M Alen 2009 Low volumetric BMD is linked to upper-limb fracture in pubertal girls and persists into adulthood: a seven-year cohort study Bone 45 480 486 10.1016/j.bone.2009.05.016 19481189
15. A Darelid C Ohlsson R Rudang JM Kindblom D Mellstrom M Lorentzon 2009 Trabecular volumetric bone mineral density is associated with previous fracture during childhood and adolescence in males-the GOOD study J Bone Miner Res 25 537 544 10.1359/jbmr.090824
16. CM Neu F Manz R Rauch A Merkel ES Schoenau 2001 Bone densities and bone size at the distal radius in healthy children and adolescents: a study using peripheral quantitative computed tomography Bone 28 227 232 1:STN:280: DC%2BD3M3hsVSqsw%3D%3D 10.1016/S8756-3282(00)00429-4 11182383
17. S Kontulainen D Liu S Manske M Jamieson H Sievanen H McKay 2007 Analyzing cortical bone cross-sectional geometry by peripheral QCT: comparison with bone histomorphometry J Clin Densitom 10 86 92 10.1016/j.jocd.2006.07.007 17289530
18. KA Ward JE Adams TN Hangartner 2005 Recommendations for thresholds for cortical bone geometry and density measurement by peripheral quantitative computed tomography Calcif Tissue Int 77 275 280 1:CAS:528:DC%2BD2MXht1GisLfF 10.1007/s00223-005-0031-x 16307388
19. A Taylor PT Konrad ME Norman HT Karcke 1997 Total body bone mineral density in young children: influence of head bone mineral density J Bone Miner Res 12 652 655 1:STN:280:DyaK2s3ls1SntA%3D%3D 10.1359/jbmr.1997.12.4.652 9101377
20. LA Landin 1983 Fracture patterns in children Acta Orthop Scand Suppl 54 1 109
21. EM Clark AR Ness JH Tobias 2008 Bone fragility contributes to the risk of fracture in children, even after moderate and severe trauma J Bone Miner Res 23 173 179 10.1359/jbmr.071010 17922615
22. CL Ogden RJ Kuczmarski KM Flegal Z Mei S Guo R Wei LM Grummer-Strawn LR Curtin AF Roche CL Johnson 2002 Centers for Disease Control and Prevention 2000 growth charts for the United States: improvements to the 1977 National Center for Health Statistics version Pediatrics 109 45 60 10.1542/peds.109.1.45 11773541
23. Tanner JM (1962) Growth at adolescence. Blackwell Scientific, Oxford
24. E Schoenau CM Neu R Rauch F Manz 2002 Gender-specific pubertal changes in volumetric cortical bone mineral density at the proximal radius Bone 31 110 113 1:STN:280:DC%2BD38zms1Wmuw%3D%3D 10.1016/S8756-3282(02)00802-5 12110422
25. TJ Cole 2000 Sympercents: symmetric percentage differences on the 100 log(e) scale simplify the presentation of log transformed data Stat Med 19 3109 3125 1:STN:280:DC%2BD3MvjsVWgug%3D%3D 10.1002/1097-0258(20001130)19:22<3109:: AID-SIM558>3.0.CO;2-F 11113946
26. JA Spadaro FW Werner RA Brenner MD Fortino LA Fay WT Edwards 1994 Cortical and trabecular bone contribute strength to the osteopenic distal radius J Orthop Res 12 211 218 1:STN:280:DyaK2c3hs12qtw%3D%3D 10.1002/jor.1100120210 8164094
27. E Sornay-Rendu S Boutroy F Munoz PD Delmas 2007 Alterations of cortical and trabecular architecture are associated with fractures in postmenopausal women, partially independent of decreased BMD measured by DXA: the OFELY study J Bone Miner Res 22 425 433 10.1359/jbmr.061206 17181395
28. J Pritchett 1991 Growth plate activity in the upper extremity Clin Orthop 268 235 242 2060215
29. F Rauch C Neu F Manz E Schoenau 2001 The development of metaphyseal cortex-implications for distal radius fractures during growth J Bone Miner Res 16 1547 1555 1:STN:280:DC%2BD3MvltlejtA%3D%3D 10.1359/jbmr.2001.16.8.1547 11499878
30. S Kirmani D Christen GH vanLenthe PR Fischer ML Bouxsein LK McCready LJ Melton 3rd BL Riggs S Amin R Muller S Khosla 2009 Bone structure at the distal radius during adolescent growth J Bone Miner Res 24 1033 1042 10.1359/jbmr.081255 19113916
31. AM Parfitt 1994 The two faces of growth: benefits and risks to bone integrity Osteoporos Int 4 382 398 1:STN:280:DyaK2M3htVyktQ%3D%3D 10.1007/BF01622201 7696836
32. G Ducher D Courteix S Meme C Magni JF Viala SL Benhamou 2005 Bone geometry in response to long-term tennis playing and its relationship with muscle volume: a quantitative magnetic resonance imaging study in tennis players Bone 37 457 466 1:STN:280:DC%2BD2Mvps1Kqtg%3D%3D 10.1016/j.bone.2005.05.014 16099730
33. ME Muller CE Webber ML Bouxsein 2003 Predicting the failure load of the distal radius Osteoporos Int 14 345 352 10.1007/s00198-003-1479-z 12730737
34. G Jones D Ma F Cameron 2006 Bone density interpretation and relevance in Caucasian children aged 9-17 years of age: insights from a population-based fracture study J Clin Densitom 9 202 209 10.1016/j.jocd.2006.02.004 16785082
35. O Johnell JA Kanis A Oden H Johansson C De Laet P Delmas JA Eisman S Fujiwara H Kroger D Mellstrom PJ Meunier LJ Melton 3rd T O'Neill H Pols J Reeve A Silman A Tenenhouse 2005 Predictive value of BMD for hip and other fractures J Bone Miner Res 20 1185 1194 10.1359/JBMR.050304 15940371
36. A Goulding IE Jones RW Taylor PJ Manning SM Williams 2000 More broken bones: a 4-year double cohort study of young girls with and without distal forearm fractures J Bone Miner Res 15 2011 2018 1:STN:280:DC%2BD3cvnslSrtw%3D%3D 10.1359/jbmr.2000.15.10.2011 11028455
37. A Goulding IE Jones RW Taylor JM Piggot D Taylor 2003 Dynamic and static tests of balance and postural sway in boys: effects of previous wrist bone fractures and high adiposity Gait Posture 17 136 141 1:STN:280: DC%2BD3s7itValtg%3D%3D 10.1016/S0966-6362(02)00161-3 12633774
38. A Goulding JE Rockell RE Black AM Grant IE Jones SM Williams 2004 Children who avoid drinking cow's milk are at increased risk for prepubertal bone fractures J Am Diet Assoc 104 250 253 10.1016/j.jada.2003.11.008 14760576
39. DC Mackey LY Lui PM Cawthon DC Bauer MC Nevitt JA Cauley TA Hillier CE Lewis E Barrett-Connor SR Cummings 2007 High-trauma fractures and low bone mineral density in older women and men JAMA 298 2381 2388 1:CAS:528: DC%2BD2sXhtlyjtL3N 10.1001/jama.298.20.2381 18042915