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Volumn 8, Issue 2, 2013, Pages

Induction of CCL8/MCP-2 by Mycobacteria through the Activation of TLR2/PI3K/Akt Signaling Pathway

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR5; MONOCYTE CHEMOTACTIC PROTEIN 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TOLL LIKE RECEPTOR 2; TUBERCULOSTATIC AGENT;

EID: 84873915591     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056815     Document Type: Article
Times cited : (29)

References (46)
  • 1
    • 70349255534 scopus 로고    scopus 로고
    • Tuberculous pleural effusion
    • Porcel JM, (2009) Tuberculous pleural effusion. Lung 187: 263-270.
    • (2009) Lung , vol.187 , pp. 263-270
    • Porcel, J.M.1
  • 2
    • 34247264526 scopus 로고    scopus 로고
    • Pleural tuberculosis in the United States: incidence and drug resistance
    • Baumann MH, Nolan R, Petrini M, Lee YC, Light RW, et al. (2007) Pleural tuberculosis in the United States: incidence and drug resistance. Chest 131: 1125-1132.
    • (2007) Chest , vol.131 , pp. 1125-1132
    • Baumann, M.H.1    Nolan, R.2    Petrini, M.3    Lee, Y.C.4    Light, R.W.5
  • 3
    • 0037141853 scopus 로고    scopus 로고
    • Clinical practice. Pleural effusion
    • Light RW, (2002) Clinical practice. Pleural effusion. N Engl J Med 346: 1971-1977.
    • (2002) N Engl J Med , vol.346 , pp. 1971-1977
    • Light, R.W.1
  • 4
    • 0036363334 scopus 로고    scopus 로고
    • Prospective study of 1,000 consecutive patients with pleural effusion. Etiology of the effusion and characteristics of the patients
    • Villena V, Lopez Encuentra A, Echave-Sustaeta J, Alvarez Martinez C, Martin Escribano P, (2002) [Prospective study of 1,000 consecutive patients with pleural effusion. Etiology of the effusion and characteristics of the patients]. Arch Bronconeumol 38: 21-26.
    • (2002) Arch Bronconeumol , vol.38 , pp. 21-26
    • Villena, V.1    Lopez Encuentra, A.2    Echave-Sustaeta, J.3    Alvarez Martinez, C.4    Martin Escribano, P.5
  • 5
    • 0030990840 scopus 로고    scopus 로고
    • Parapneumonic effusion and empyema
    • Hamm H, Light RW, (1997) Parapneumonic effusion and empyema. Eur Respir J 10: 1150-1156.
    • (1997) Eur Respir J , vol.10 , pp. 1150-1156
    • Hamm, H.1    Light, R.W.2
  • 6
    • 65349123115 scopus 로고    scopus 로고
    • Interaction of Mycobacterium tuberculosis with the host: consequences for vaccine development
    • Dietrich J, Doherty TM, (2009) Interaction of Mycobacterium tuberculosis with the host: consequences for vaccine development. APMIS 117: 440-457.
    • (2009) APMIS , vol.117 , pp. 440-457
    • Dietrich, J.1    Doherty, T.M.2
  • 7
    • 67650932256 scopus 로고    scopus 로고
    • Cell-mediated immune responses in tuberculosis
    • Cooper AM, (2009) Cell-mediated immune responses in tuberculosis. Annu Rev Immunol 27: 393-422.
    • (2009) Annu Rev Immunol , vol.27 , pp. 393-422
    • Cooper, A.M.1
  • 8
    • 40749159713 scopus 로고    scopus 로고
    • Distinct, specific IL-17- and IL-22-producing CD4+ T cell subsets contribute to the human anti-mycobacterial immune response
    • Scriba TJ, Kalsdorf B, Abrahams DA, Isaacs F, Hofmeister J, et al. (2008) Distinct, specific IL-17- and IL-22-producing CD4+ T cell subsets contribute to the human anti-mycobacterial immune response. J Immunol 180: 1962-1970.
    • (2008) J Immunol , vol.180 , pp. 1962-1970
    • Scriba, T.J.1    Kalsdorf, B.2    Abrahams, D.A.3    Isaacs, F.4    Hofmeister, J.5
  • 10
    • 77950190665 scopus 로고    scopus 로고
    • CCL22 is involved in the recruitment of CD4+CD25 high T cells into tuberculous pleural effusions
    • Wu C, Zhou Q, Qin XJ, Qin SM, Shi HZ, (2010) CCL22 is involved in the recruitment of CD4+CD25 high T cells into tuberculous pleural effusions. Respirology 15: 522-529.
    • (2010) Respirology , vol.15 , pp. 522-529
    • Wu, C.1    Zhou, Q.2    Qin, X.J.3    Qin, S.M.4    Shi, H.Z.5
  • 11
    • 84857394050 scopus 로고    scopus 로고
    • Differentiation and recruitment of Th9 cells stimulated by pleural mesothelial cells in human Mycobacterium tuberculosis infection
    • Ye ZJ, Yuan ML, Zhou Q, Du RH, Yang WB, et al. (2012) Differentiation and recruitment of Th9 cells stimulated by pleural mesothelial cells in human Mycobacterium tuberculosis infection. PLoS One 7: e31710.
    • (2012) PLoS One , vol.7
    • Ye, Z.J.1    Yuan, M.L.2    Zhou, Q.3    Du, R.H.4    Yang, W.B.5
  • 12
    • 84863262837 scopus 로고    scopus 로고
    • Differentiation and recruitment of IL-22-producing helper T cells stimulated by pleural mesothelial cells in tuberculous pleurisy
    • Ye ZJ, Zhou Q, Yuan ML, Du RH, Yang WB, et al. (2012) Differentiation and recruitment of IL-22-producing helper T cells stimulated by pleural mesothelial cells in tuberculous pleurisy. Am J Respir Crit Care Med 185: 660-669.
    • (2012) Am J Respir Crit Care Med , vol.185 , pp. 660-669
    • Ye, Z.J.1    Zhou, Q.2    Yuan, M.L.3    Du, R.H.4    Yang, W.B.5
  • 13
    • 84859482440 scopus 로고    scopus 로고
    • CXCL12 as a biological marker for the diagnosis of tuberculous pleurisy
    • Kohmo S, Kijima T, Mori M, Minami T, Namba Y, et al. (2012) CXCL12 as a biological marker for the diagnosis of tuberculous pleurisy. Tuberculosis (Edinb) 92: 248-252.
    • (2012) Tuberculosis (Edinb) , vol.92 , pp. 248-252
    • Kohmo, S.1    Kijima, T.2    Mori, M.3    Minami, T.4    Namba, Y.5
  • 14
    • 62849089035 scopus 로고    scopus 로고
    • Clinical diagnostic utility of IP-10 and LAM antigen levels for the diagnosis of tuberculous pleural effusions in a high burden setting
    • Dheda K, Van-Zyl Smit RN, Sechi LA, Badri M, Meldau R, et al. (2009) Clinical diagnostic utility of IP-10 and LAM antigen levels for the diagnosis of tuberculous pleural effusions in a high burden setting. PLoS One 4: e4689.
    • (2009) PLoS One , vol.4
    • Dheda, K.1    Van-Zyl Smit, R.N.2    Sechi, L.A.3    Badri, M.4    Meldau, R.5
  • 15
    • 51649128995 scopus 로고    scopus 로고
    • Diagnostic utility of interferon-gamma-induced protein of 10 kDa (IP-10) in tuberculous pleurisy
    • Supriya P, Chandrasekaran P, Das SD, (2008) Diagnostic utility of interferon-gamma-induced protein of 10 kDa (IP-10) in tuberculous pleurisy. Diagn Microbiol Infect Dis 62: 186-192.
    • (2008) Diagn Microbiol Infect Dis , vol.62 , pp. 186-192
    • Supriya, P.1    Chandrasekaran, P.2    Das, S.D.3
  • 16
    • 39749183027 scopus 로고    scopus 로고
    • Expression of CXC and CC type of chemokines and its receptors in tuberculous and non-tuberculous effusions
    • R L
    • Pokkali S, Das SD, R L, (2008) Expression of CXC and CC type of chemokines and its receptors in tuberculous and non-tuberculous effusions. Cytokine 41: 307-314.
    • (2008) Cytokine , vol.41 , pp. 307-314
    • Pokkali, S.1    Das, S.D.2
  • 17
    • 33947398046 scopus 로고    scopus 로고
    • Diagnosis and treatment of tuberculous pleural effusion in 2006
    • Gopi A, Madhavan SM, Sharma SK, Sahn SA, (2007) Diagnosis and treatment of tuberculous pleural effusion in 2006. Chest 131: 880-889.
    • (2007) Chest , vol.131 , pp. 880-889
    • Gopi, A.1    Madhavan, S.M.2    Sharma, S.K.3    Sahn, S.A.4
  • 18
    • 0034792227 scopus 로고    scopus 로고
    • Changes in gene expression in macrophages infected with Mycobacterium tuberculosis: a combined transcriptomic and proteomic approach
    • Ragno S, Romano M, Howell S, Pappin DJ, Jenner PJ, et al. (2001) Changes in gene expression in macrophages infected with Mycobacterium tuberculosis: a combined transcriptomic and proteomic approach. Immunology 104: 99-108.
    • (2001) Immunology , vol.104 , pp. 99-108
    • Ragno, S.1    Romano, M.2    Howell, S.3    Pappin, D.J.4    Jenner, P.J.5
  • 19
    • 0028359960 scopus 로고
    • Induction of monocyte chemotactic proteins MCP-1 and MCP-2 in human fibroblasts and leukocytes by cytokines and cytokine inducers. Chemical synthesis of MCP-2 and development of a specific RIA
    • Van Damme J, Proost P, Put W, Arens S, Lenaerts JP, et al. (1994) Induction of monocyte chemotactic proteins MCP-1 and MCP-2 in human fibroblasts and leukocytes by cytokines and cytokine inducers. Chemical synthesis of MCP-2 and development of a specific RIA. J Immunol 152: 5495-5502.
    • (1994) J Immunol , vol.152 , pp. 5495-5502
    • Van Damme, J.1    Proost, P.2    Put, W.3    Arens, S.4    Lenaerts, J.P.5
  • 20
    • 0035257205 scopus 로고    scopus 로고
    • Lymphocyte traffic control by chemokines
    • Moser B, Loetscher P, (2001) Lymphocyte traffic control by chemokines. Nat Immunol 2: 123-128.
    • (2001) Nat Immunol , vol.2 , pp. 123-128
    • Moser, B.1    Loetscher, P.2
  • 21
    • 0032211717 scopus 로고    scopus 로고
    • CCR5 has an expanded ligand-binding repertoire and is the primary receptor used by MCP-2 on activated T cells
    • Ruffing N, Sullivan N, Sharmeen L, Sodroski J, Wu L, (1998) CCR5 has an expanded ligand-binding repertoire and is the primary receptor used by MCP-2 on activated T cells. Cell Immunol 189: 160-168.
    • (1998) Cell Immunol , vol.189 , pp. 160-168
    • Ruffing, N.1    Sullivan, N.2    Sharmeen, L.3    Sodroski, J.4    Wu, L.5
  • 22
    • 0031010175 scopus 로고    scopus 로고
    • Monocyte chemotactic protein-2 (MCP-2) uses CCR1 and CCR2B as its functional receptors
    • Gong X, Gong W, Kuhns DB, Ben-Baruch A, Howard OM, et al. (1997) Monocyte chemotactic protein-2 (MCP-2) uses CCR1 and CCR2B as its functional receptors. J Biol Chem 272: 11682-11685.
    • (1997) J Biol Chem , vol.272 , pp. 11682-11685
    • Gong, X.1    Gong, W.2    Kuhns, D.B.3    Ben-Baruch, A.4    Howard, O.M.5
  • 23
    • 34247232796 scopus 로고    scopus 로고
    • Diagnostic value of interferon-gamma in tuberculous pleurisy: a metaanalysis
    • Jiang J, Shi HZ, Liang QL, Qin SM, Qin XJ, (2007) Diagnostic value of interferon-gamma in tuberculous pleurisy: a metaanalysis. Chest 131: 1133-1141.
    • (2007) Chest , vol.131 , pp. 1133-1141
    • Jiang, J.1    Shi, H.Z.2    Liang, Q.L.3    Qin, S.M.4    Qin, X.J.5
  • 24
    • 79955111092 scopus 로고    scopus 로고
    • Macrophages and control of granulomatous inflammation in tuberculosis
    • Flynn JL, Chan J, Lin PL, (2011) Macrophages and control of granulomatous inflammation in tuberculosis. Mucosal Immunol 4: 271-278.
    • (2011) Mucosal Immunol , vol.4 , pp. 271-278
    • Flynn, J.L.1    Chan, J.2    Lin, P.L.3
  • 25
    • 79955521362 scopus 로고    scopus 로고
    • Macrophage polarization and bacterial infections
    • Mege JL, Mehraj V, Capo C, (2011) Macrophage polarization and bacterial infections. Curr Opin Infect Dis 24: 230-234.
    • (2011) Curr Opin Infect Dis , vol.24 , pp. 230-234
    • Mege, J.L.1    Mehraj, V.2    Capo, C.3
  • 26
    • 79955082538 scopus 로고    scopus 로고
    • Apoptosis is an innate defense function of macrophages against Mycobacterium tuberculosis
    • Behar SM, Martin CJ, Booty MG, Nishimura T, Zhao X, et al. (2011) Apoptosis is an innate defense function of macrophages against Mycobacterium tuberculosis. Mucosal Immunol 4: 279-287.
    • (2011) Mucosal Immunol , vol.4 , pp. 279-287
    • Behar, S.M.1    Martin, C.J.2    Booty, M.G.3    Nishimura, T.4    Zhao, X.5
  • 27
    • 84863622609 scopus 로고    scopus 로고
    • Cell origins and diagnostic accuracy of interleukin 27 in pleural effusions
    • Yang WB, Liang QL, Ye ZJ, Niu CM, Ma WL, et al. (2012) Cell origins and diagnostic accuracy of interleukin 27 in pleural effusions. PLoS One 7: e40450.
    • (2012) PLoS One , vol.7
    • Yang, W.B.1    Liang, Q.L.2    Ye, Z.J.3    Niu, C.M.4    Ma, W.L.5
  • 28
    • 80052345448 scopus 로고    scopus 로고
    • A delicate dance: host response to mycobacteria
    • Huynh KK, Joshi SA, Brown EJ, (2011) A delicate dance: host response to mycobacteria. Curr Opin Immunol 23: 464-472.
    • (2011) Curr Opin Immunol , vol.23 , pp. 464-472
    • Huynh, K.K.1    Joshi, S.A.2    Brown, E.J.3
  • 30
    • 0022270794 scopus 로고
    • Bacillus Calmette-Guerin-stimulated neutrophils release chemotaxins for monocytes in rabbit pleural spaces and in vitro
    • Antony VB, Sahn SA, Antony AC, Repine JE, (1985) Bacillus Calmette-Guerin-stimulated neutrophils release chemotaxins for monocytes in rabbit pleural spaces and in vitro. J Clin Invest 76: 1514-1521.
    • (1985) J Clin Invest , vol.76 , pp. 1514-1521
    • Antony, V.B.1    Sahn, S.A.2    Antony, A.C.3    Repine, J.E.4
  • 31
    • 0024500229 scopus 로고
    • Compartmentalization of a CD4+ T lymphocyte subpopulation in tuberculous pleuritis
    • Barnes PF, Mistry SD, Cooper CL, Pirmez C, Rea TH, et al. (1989) Compartmentalization of a CD4+ T lymphocyte subpopulation in tuberculous pleuritis. J Immunol 142: 1114-1119.
    • (1989) J Immunol , vol.142 , pp. 1114-1119
    • Barnes, P.F.1    Mistry, S.D.2    Cooper, C.L.3    Pirmez, C.4    Rea, T.H.5
  • 32
    • 23844482897 scopus 로고    scopus 로고
    • Polarized helper T cells in tubercular pleural effusion: phenotypic identity and selective recruitment
    • Mitra DK, Sharma SK, Dinda AK, Bindra MS, Madan B, et al. (2005) Polarized helper T cells in tubercular pleural effusion: phenotypic identity and selective recruitment. Eur J Immunol 35: 2367-2375.
    • (2005) Eur J Immunol , vol.35 , pp. 2367-2375
    • Mitra, D.K.1    Sharma, S.K.2    Dinda, A.K.3    Bindra, M.S.4    Madan, B.5
  • 33
    • 0027433118 scopus 로고
    • Up-regulation of alveolar macrophage platelet-derived growth factor-B (PDGF-B) mRNA by interferon-gamma from Mycobacterium tuberculosis antigen (PPD)-stimulated lymphocytes
    • Wangoo A, Taylor IK, Haynes AR, Shaw RJ, (1993) Up-regulation of alveolar macrophage platelet-derived growth factor-B (PDGF-B) mRNA by interferon-gamma from Mycobacterium tuberculosis antigen (PPD)-stimulated lymphocytes. Clin Exp Immunol 94: 43-50.
    • (1993) Clin Exp Immunol , vol.94 , pp. 43-50
    • Wangoo, A.1    Taylor, I.K.2    Haynes, A.R.3    Shaw, R.J.4
  • 34
    • 11844258823 scopus 로고    scopus 로고
    • Post-treatment changes of six cytokines in active pulmonary tuberculosis: differences between patients with stable or increased fibrosis
    • Ameglio F, Casarini M, Capoluongo E, Mattia P, Puglisi G, et al. (2005) Post-treatment changes of six cytokines in active pulmonary tuberculosis: differences between patients with stable or increased fibrosis. Int J Tuberc Lung Dis 9: 98-104.
    • (2005) Int J Tuberc Lung Dis , vol.9 , pp. 98-104
    • Ameglio, F.1    Casarini, M.2    Capoluongo, E.3    Mattia, P.4    Puglisi, G.5
  • 35
    • 41149123875 scopus 로고    scopus 로고
    • Diagnostic accuracy of adenosine deaminase in tuberculous pleurisy: a meta-analysis
    • Liang QL, Shi HZ, Wang K, Qin SM, Qin XJ, (2008) Diagnostic accuracy of adenosine deaminase in tuberculous pleurisy: a meta-analysis. Respir Med 102: 744-754.
    • (2008) Respir Med , vol.102 , pp. 744-754
    • Liang, Q.L.1    Shi, H.Z.2    Wang, K.3    Qin, S.M.4    Qin, X.J.5
  • 36
    • 47049104941 scopus 로고    scopus 로고
    • Novel tests for diagnosing tuberculous pleural effusion: what works and what does not?
    • Trajman A, Pai M, Dheda K, van Zyl Smit R, Zwerling AA, et al. (2008) Novel tests for diagnosing tuberculous pleural effusion: what works and what does not? Eur Respir J 31: 1098-1106.
    • (2008) Eur Respir J , vol.31 , pp. 1098-1106
    • Trajman, A.1    Pai, M.2    Dheda, K.3    van Zyl Smit, R.4    Zwerling, A.A.5
  • 37
    • 58849126455 scopus 로고    scopus 로고
    • Evaluating the potential of IP-10 and MCP-2 as biomarkers for the diagnosis of tuberculosis
    • Ruhwald M, Bodmer T, Maier C, Jepsen M, Haaland MB, et al. (2008) Evaluating the potential of IP-10 and MCP-2 as biomarkers for the diagnosis of tuberculosis. Eur Respir J 32: 1607-1615.
    • (2008) Eur Respir J , vol.32 , pp. 1607-1615
    • Ruhwald, M.1    Bodmer, T.2    Maier, C.3    Jepsen, M.4    Haaland, M.B.5
  • 38
    • 0028788487 scopus 로고
    • Plasma levels of the chemokines monocyte chemotactic proteins-1 and -2 are elevated in human sepsis
    • Bossink AW, Paemen L, Jansen PM, Hack CE, Thijs LG, et al. (1995) Plasma levels of the chemokines monocyte chemotactic proteins-1 and-2 are elevated in human sepsis. Blood 86: 3841-3847.
    • (1995) Blood , vol.86 , pp. 3841-3847
    • Bossink, A.W.1    Paemen, L.2    Jansen, P.M.3    Hack, C.E.4    Thijs, L.G.5
  • 39
    • 62149125177 scopus 로고    scopus 로고
    • Upregulation of plasma CCL8 in mouse model of graft-vs-host disease
    • Ota A, Yamamoto M, Hori T, Miyai S, Naishiro Y, et al. (2009) Upregulation of plasma CCL8 in mouse model of graft-vs-host disease. Exp Hematol 37: 525-531.
    • (2009) Exp Hematol , vol.37 , pp. 525-531
    • Ota, A.1    Yamamoto, M.2    Hori, T.3    Miyai, S.4    Naishiro, Y.5
  • 40
    • 80054697450 scopus 로고    scopus 로고
    • Early expression of plasma CCL8 closely correlates with survival rate of acute graft-vs.-host disease in mice
    • Yamamoto M, Ota A, Hori T, Imai S, Sohma H, et al. (2011) Early expression of plasma CCL8 closely correlates with survival rate of acute graft-vs.-host disease in mice. Exp Hematol 39: 1101-1112.
    • (2011) Exp Hematol , vol.39 , pp. 1101-1112
    • Yamamoto, M.1    Ota, A.2    Hori, T.3    Imai, S.4    Sohma, H.5
  • 41
    • 67650591022 scopus 로고    scopus 로고
    • Gene expression in HIV-1/Mycobacterium tuberculosis co-infected macrophages is dominated by M. tuberculosis
    • Maddocks S, Scandurra GM, Nourse C, Bye C, Williams RB, et al. (2009) Gene expression in HIV-1/Mycobacterium tuberculosis co-infected macrophages is dominated by M. tuberculosis. Tuberculosis (Edinb) 89: 285-293.
    • (2009) Tuberculosis (Edinb) , vol.89 , pp. 285-293
    • Maddocks, S.1    Scandurra, G.M.2    Nourse, C.3    Bye, C.4    Williams, R.B.5
  • 42
    • 9144232901 scopus 로고    scopus 로고
    • Chemokine secretion of rheumatoid arthritis synovial fibroblasts stimulated by Toll-like receptor 2 ligands
    • Pierer M, Rethage J, Seibl R, Lauener R, Brentano F, et al. (2004) Chemokine secretion of rheumatoid arthritis synovial fibroblasts stimulated by Toll-like receptor 2 ligands. J Immunol 172: 1256-1265.
    • (2004) J Immunol , vol.172 , pp. 1256-1265
    • Pierer, M.1    Rethage, J.2    Seibl, R.3    Lauener, R.4    Brentano, F.5
  • 43
    • 84861202872 scopus 로고    scopus 로고
    • LPS-induced chemokine expression in both MyD88-dependent and -independent manners is regulated by Cot/Tpl2-ERK axis in macrophages
    • Bandow K, Kusuyama J, Shamoto M, Kakimoto K, Ohnishi T, et al. (2012) LPS-induced chemokine expression in both MyD88-dependent and-independent manners is regulated by Cot/Tpl2-ERK axis in macrophages. FEBS Lett 586: 1540-1546.
    • (2012) FEBS Lett , vol.586 , pp. 1540-1546
    • Bandow, K.1    Kusuyama, J.2    Shamoto, M.3    Kakimoto, K.4    Ohnishi, T.5
  • 44
    • 77949550080 scopus 로고    scopus 로고
    • Regulation of antigen presentation by Mycobacterium tuberculosis: a role for Toll-like receptors
    • Harding CV, Boom WH, (2010) Regulation of antigen presentation by Mycobacterium tuberculosis: a role for Toll-like receptors. Nat Rev Microbiol 8: 296-307.
    • (2010) Nat Rev Microbiol , vol.8 , pp. 296-307
    • Harding, C.V.1    Boom, W.H.2
  • 45
    • 33749255932 scopus 로고    scopus 로고
    • Cytokine and chemokine transcription profile during Mycoplasma pulmonis infection in susceptible and resistant strains of mice: macrophage inflammatory protein 1beta (CCL4) and monocyte chemoattractant protein 2 (CCL8) and accumulation of CCR5+ Th cells
    • Sun X, Jones HP, Hodge LM, Simecka JW, (2006) Cytokine and chemokine transcription profile during Mycoplasma pulmonis infection in susceptible and resistant strains of mice: macrophage inflammatory protein 1beta (CCL4) and monocyte chemoattractant protein 2 (CCL8) and accumulation of CCR5+ Th cells. Infect Immun 74: 5943-5954.
    • (2006) Infect Immun , vol.74 , pp. 5943-5954
    • Sun, X.1    Jones, H.P.2    Hodge, L.M.3    Simecka, J.W.4
  • 46
    • 46749113860 scopus 로고    scopus 로고
    • MyD88-independent activation of a novel actin-Cdc42/Rac pathway is required for Toll-like receptor-stimulated phagocytosis
    • Kong L, Ge BX, (2008) MyD88-independent activation of a novel actin-Cdc42/Rac pathway is required for Toll-like receptor-stimulated phagocytosis. Cell Res 18: 745-755.
    • (2008) Cell Res , vol.18 , pp. 745-755
    • Kong, L.1    Ge, B.X.2


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