메뉴 건너뛰기




Volumn 31, Issue 3, 2013, Pages 214-223

Treadmill exercise ameliorates symptoms of methimazole-induced hypothyroidism through enhancing neurogenesis and suppressing apoptosis in the hippocampus of rat pups

Author keywords

Apoptosis; Hypothyroidism; Neurogenesis; Short term memory; Spatial learning ability; Treadmill exercise

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CASPASE 3; DOUBLECORTIN; LIOTHYRONINE; PROTEIN BAX; PROTEIN BCL 2; THIAMAZOLE; THYROXINE;

EID: 84873899217     PISSN: 07365748     EISSN: 1873474X     Source Type: Journal    
DOI: 10.1016/j.ijdevneu.2013.01.003     Document Type: Article
Times cited : (50)

References (49)
  • 1
    • 11844275246 scopus 로고    scopus 로고
    • The exercise-induced expression of BDNF within the hippocampus varies across life-span
    • Adlard P.A., Perreau V.M., Cotman C.W. The exercise-induced expression of BDNF within the hippocampus varies across life-span. Neurobiology of Aging 2005, 26:511-520.
    • (2005) Neurobiology of Aging , vol.26 , pp. 511-520
    • Adlard, P.A.1    Perreau, V.M.2    Cotman, C.W.3
  • 2
    • 77955468569 scopus 로고    scopus 로고
    • Effects of experimentally induced maternal hypothyroidism and hyperthyroidism on the development of rat offspring: I. The development of the thyroid hormones-neurotransmitters and adenosinergic system interactions
    • Ahmed O.M., Abd El-Tawab S.M., Ahmed R.G. Effects of experimentally induced maternal hypothyroidism and hyperthyroidism on the development of rat offspring: I. The development of the thyroid hormones-neurotransmitters and adenosinergic system interactions. International Journal of Developmental Neuroscience 2010, 28:437-454.
    • (2010) International Journal of Developmental Neuroscience , vol.28 , pp. 437-454
    • Ahmed, O.M.1    Abd El-Tawab, S.M.2    Ahmed, R.G.3
  • 7
    • 83955162965 scopus 로고    scopus 로고
    • Effects of postnatal treadmill exercise on apoptotic neuronal cell death and cell proliferation of maternal-separated rat pups
    • Baek S.S., Jun T.W., Kim K.J., Shin M.S., Kang S.Y., Kim C.J. Effects of postnatal treadmill exercise on apoptotic neuronal cell death and cell proliferation of maternal-separated rat pups. Brain and Development 2012, 34:45-56.
    • (2012) Brain and Development , vol.34 , pp. 45-56
    • Baek, S.S.1    Jun, T.W.2    Kim, K.J.3    Shin, M.S.4    Kang, S.Y.5    Kim, C.J.6
  • 8
    • 0035051176 scopus 로고    scopus 로고
    • The nature of apoptosis in the thyroid and the role it may play in autoimmune thyroid disease
    • Baker J.R. The nature of apoptosis in the thyroid and the role it may play in autoimmune thyroid disease. Thyroid 2001, 11:245-247.
    • (2001) Thyroid , vol.11 , pp. 245-247
    • Baker, J.R.1
  • 10
    • 34548770599 scopus 로고    scopus 로고
    • Brain plasticity mechanisms and memory: a party of four
    • Bruel-Jungerman E., Davis S., Laroche S. Brain plasticity mechanisms and memory: a party of four. Neuroscientist 2007, 13:492-505.
    • (2007) Neuroscientist , vol.13 , pp. 492-505
    • Bruel-Jungerman, E.1    Davis, S.2    Laroche, S.3
  • 14
    • 0036716281 scopus 로고    scopus 로고
    • The Bcl-2 family: regulators of the cellular life-or-death switch
    • Cory S., Adams J.M. The Bcl-2 family: regulators of the cellular life-or-death switch. Nature Reviews Cancer 2002, 2:647-656.
    • (2002) Nature Reviews Cancer , vol.2 , pp. 647-656
    • Cory, S.1    Adams, J.M.2
  • 16
    • 67249141007 scopus 로고    scopus 로고
    • Physical exercise and cognitive recovery in acquired brain injury: a review of the literature
    • Devine J.M., Zafonte R.D. Physical exercise and cognitive recovery in acquired brain injury: a review of the literature. Physical Medicine and Rehabilitation 2009, 1:560-575.
    • (2009) Physical Medicine and Rehabilitation , vol.1 , pp. 560-575
    • Devine, J.M.1    Zafonte, R.D.2
  • 17
    • 28444447357 scopus 로고    scopus 로고
    • Neurotrophic factors and regulation of mood: role of exercise, diet and metabolism
    • Duman R.S. Neurotrophic factors and regulation of mood: role of exercise, diet and metabolism. Neurobiology of Aging 2005, 26:S88-S93.
    • (2005) Neurobiology of Aging , vol.26
    • Duman, R.S.1
  • 18
    • 5344232095 scopus 로고    scopus 로고
    • Hippocampus: cognitive processes and neural representations that underlie declarative memory
    • Eichenbaum H. Hippocampus: cognitive processes and neural representations that underlie declarative memory. Neuron 2004, 44:109-120.
    • (2004) Neuron , vol.44 , pp. 109-120
    • Eichenbaum, H.1
  • 20
    • 0442307920 scopus 로고    scopus 로고
    • Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo
    • Farmer J., Zhao X., van Praag H., Wodtke K., Gage F.H., Christie B.R. Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo. Neuroscience 2004, 124:71-79.
    • (2004) Neuroscience , vol.124 , pp. 71-79
    • Farmer, J.1    Zhao, X.2    van Praag, H.3    Wodtke, K.4    Gage, F.H.5    Christie, B.R.6
  • 23
    • 1542395750 scopus 로고    scopus 로고
    • Hypothyroidism impairs late LTP in CA1 region but not in dentate gyrus of the intact rat hippocampus: MAPK involvement
    • Gerges N.Z., Alkadhi K.A. Hypothyroidism impairs late LTP in CA1 region but not in dentate gyrus of the intact rat hippocampus: MAPK involvement. Hippocampus 2004, 14:40-45.
    • (2004) Hippocampus , vol.14 , pp. 40-45
    • Gerges, N.Z.1    Alkadhi, K.A.2
  • 24
    • 31344479094 scopus 로고    scopus 로고
    • Dose-dependent reductions in spatial learning and synaptic function in the dentate gyrus of adult rats following developmental thyroid hormone insufficiency
    • Gilbert M.E., Sui L. Dose-dependent reductions in spatial learning and synaptic function in the dentate gyrus of adult rats following developmental thyroid hormone insufficiency. Brain Research 2006, 1069:10-22.
    • (2006) Brain Research , vol.1069 , pp. 10-22
    • Gilbert, M.E.1    Sui, L.2
  • 25
    • 4644224283 scopus 로고    scopus 로고
    • Expression of brain-derived neurotrophic factor in the rat median eminence cells with sensitivity to stress
    • Givalois L., Arancibia S., Alonso G., Tapia-Arancibia L. Expression of brain-derived neurotrophic factor in the rat median eminence cells with sensitivity to stress. Endocrinology 2004, 145:4737-4747.
    • (2004) Endocrinology , vol.145 , pp. 4737-4747
    • Givalois, L.1    Arancibia, S.2    Alonso, G.3    Tapia-Arancibia, L.4
  • 26
    • 77951095295 scopus 로고    scopus 로고
    • Developmental iodine deficiency and hypothyroidism impair neural development in rat hippocampus: involvement of doublecortin and NCAM-180
    • Gong J., Liu W., Dong J., Wang Y., Xu H., Wei W., Zhong J., Xi Q., Chen J. Developmental iodine deficiency and hypothyroidism impair neural development in rat hippocampus: involvement of doublecortin and NCAM-180. BMC Neuroscience 2010, 11:50-59.
    • (2010) BMC Neuroscience , vol.11 , pp. 50-59
    • Gong, J.1    Liu, W.2    Dong, J.3    Wang, Y.4    Xu, H.5    Wei, W.6    Zhong, J.7    Xi, Q.8    Chen, J.9
  • 28
    • 0030937293 scopus 로고    scopus 로고
    • More hippocampal neurons in adult mice living in an enriched environment
    • Kempermann G., Kuhn H.G. More hippocampal neurons in adult mice living in an enriched environment. Nature 1997, 386:493-495.
    • (1997) Nature , vol.386 , pp. 493-495
    • Kempermann, G.1    Kuhn, H.G.2
  • 29
    • 84863428817 scopus 로고    scopus 로고
    • Alcohol exposure induces depression-like behavior by decreasing hippocampal neuronal proliferation through inhibition of the BDNF-ERK pathway in gerbils
    • Kim J.E., Ji E.S., Seo J.H., Lee M.H., Cho S., Park Y.K., Seo T.B., Kim C.J. Alcohol exposure induces depression-like behavior by decreasing hippocampal neuronal proliferation through inhibition of the BDNF-ERK pathway in gerbils. Animal Cells and Systems 2012, 16:190-197.
    • (2012) Animal Cells and Systems , vol.16 , pp. 190-197
    • Kim, J.E.1    Ji, E.S.2    Seo, J.H.3    Lee, M.H.4    Cho, S.5    Park, Y.K.6    Seo, T.B.7    Kim, C.J.8
  • 30
    • 77951093119 scopus 로고    scopus 로고
    • Treadmill exercise prevents aging-induced failure of memory through an increase in neurogenesis and suppression of apoptosis in rat hippocampus
    • Kim S.E., Ko I.G., Kim B.K., Shin M.S., Cho S., Kim C.J., Kim S.H., Baek S.S., Lee E.K., Jee Y.S. Treadmill exercise prevents aging-induced failure of memory through an increase in neurogenesis and suppression of apoptosis in rat hippocampus. Experimental Gerontology 2010, 45:357-365.
    • (2010) Experimental Gerontology , vol.45 , pp. 357-365
    • Kim, S.E.1    Ko, I.G.2    Kim, B.K.3    Shin, M.S.4    Cho, S.5    Kim, C.J.6    Kim, S.H.7    Baek, S.S.8    Lee, E.K.9    Jee, Y.S.10
  • 31
    • 66549109462 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis and related neurotrophic factors
    • Lee E., Son H. Adult hippocampal neurogenesis and related neurotrophic factors. BMB Reports 2009, 42:239-244.
    • (2009) BMB Reports , vol.42 , pp. 239-244
    • Lee, E.1    Son, H.2
  • 32
    • 84859178966 scopus 로고    scopus 로고
    • Infusion of BDNF into the nucleus accumbens of aged rats improves cognition and structural synaptic plasticity through PI3K-ILK-Akt signaling
    • Li M., Dai F.R., Du X.P., Yang Q.D., Zhang X., Chen Y. Infusion of BDNF into the nucleus accumbens of aged rats improves cognition and structural synaptic plasticity through PI3K-ILK-Akt signaling. Behavioural Brain Research 2012, 16(231):146L 153.
    • (2012) Behavioural Brain Research , vol.16 , Issue.231
    • Li, M.1    Dai, F.R.2    Du, X.P.3    Yang, Q.D.4    Zhang, X.5    Chen, Y.6
  • 33
    • 33846442469 scopus 로고    scopus 로고
    • Effect of chronic and acute low-frequency repetitive transcranial magnetic stimulation on spatial memory in rats
    • Li W., Yang Y., Ye Q., Yang B., Wang Z. Effect of chronic and acute low-frequency repetitive transcranial magnetic stimulation on spatial memory in rats. Brain Research Bulletin 2007, 71:493-500.
    • (2007) Brain Research Bulletin , vol.71 , pp. 493-500
    • Li, W.1    Yang, Y.2    Ye, Q.3    Yang, B.4    Wang, Z.5
  • 34
    • 23244458855 scopus 로고    scopus 로고
    • Adult neurogenesis in the mammalian central nervous system
    • Ming G., Song H. Adult neurogenesis in the mammalian central nervous system. Annual Review of Neuroscience 2005, 28:223-250.
    • (2005) Annual Review of Neuroscience , vol.28 , pp. 223-250
    • Ming, G.1    Song, H.2
  • 35
    • 0029557895 scopus 로고
    • Thyroid hormone promotes Bcl-2 expression and prevents apoptosis of early differentiating cerebellar granule neurons
    • Müller Y., Rocchi E., Lazaro J.B., Clos J. Thyroid hormone promotes Bcl-2 expression and prevents apoptosis of early differentiating cerebellar granule neurons. International Journal of Developmental Neuroscience 1995, 13:871-885.
    • (1995) International Journal of Developmental Neuroscience , vol.13 , pp. 871-885
    • Müller, Y.1    Rocchi, E.2    Lazaro, J.B.3    Clos, J.4
  • 36
    • 33845283925 scopus 로고    scopus 로고
    • The effects of forced exercise on hippocampal plasticity in the rat: a comparison of LTP, spatial- and non-spatial learning
    • O'Callaghan R.M., Ohle R., Kelly A.M. The effects of forced exercise on hippocampal plasticity in the rat: a comparison of LTP, spatial- and non-spatial learning. Behavioural Brain Research 2007, 176:362-366.
    • (2007) Behavioural Brain Research , vol.176 , pp. 362-366
    • O'Callaghan, R.M.1    Ohle, R.2    Kelly, A.M.3
  • 37
    • 0035234670 scopus 로고    scopus 로고
    • Neurotrophins as synaptic modulators
    • Poo M.M. Neurotrophins as synaptic modulators. Nature Reviews Neuroscience 2001, 2:24-32.
    • (2001) Nature Reviews Neuroscience , vol.2 , pp. 24-32
    • Poo, M.M.1
  • 38
    • 0141919620 scopus 로고    scopus 로고
    • Exercise increases hippocampal neurogenesis to high levels but does not improve spatial learning in mice bred for increased voluntary wheel running
    • Rhodes J.S., van Praag H., Jeffrey S., Girard I., Mitchell G.S., Garland T., Gage F.H. Exercise increases hippocampal neurogenesis to high levels but does not improve spatial learning in mice bred for increased voluntary wheel running. Behavioral Neuroscience 2003, 117:1006-1016.
    • (2003) Behavioral Neuroscience , vol.117 , pp. 1006-1016
    • Rhodes, J.S.1    van Praag, H.2    Jeffrey, S.3    Girard, I.4    Mitchell, G.S.5    Garland, T.6    Gage, F.H.7
  • 39
    • 1842556763 scopus 로고    scopus 로고
    • Dendritic growth cones and recurrent basal dendrites are typical features of newly generated dentate granule cells in the adult hippocampus
    • Ribak C.E., Korn M.J., Shan Z., Obenaus A. Dendritic growth cones and recurrent basal dendrites are typical features of newly generated dentate granule cells in the adult hippocampus. Brain Research 2004, 1000:195-199.
    • (2004) Brain Research , vol.1000 , pp. 195-199
    • Ribak, C.E.1    Korn, M.J.2    Shan, Z.3    Obenaus, A.4
  • 41
    • 0026785658 scopus 로고
    • The effect of endurance training on serum triiodothyronine kinetics in man: physical conditioning marked by enhanced thyroid hormone metabolism
    • Rone J.K., Dons R.F., Reed H.L. The effect of endurance training on serum triiodothyronine kinetics in man: physical conditioning marked by enhanced thyroid hormone metabolism. Clinical Endocrinology (Oxford) 1992, 37:325-330.
    • (1992) Clinical Endocrinology (Oxford) , vol.37 , pp. 325-330
    • Rone, J.K.1    Dons, R.F.2    Reed, H.L.3
  • 44
    • 0037258362 scopus 로고    scopus 로고
    • Hypothyroidism alters the expression of Bcl-2 family genes to induce enhanced apoptosis in the developing cerebellum
    • Singh R., Upadhyay G., Kumar S., Kapoor A., Kumar A., Tiwari M., Godbole M.M. Hypothyroidism alters the expression of Bcl-2 family genes to induce enhanced apoptosis in the developing cerebellum. Journal of Endocrinology 2003, 176:39-46.
    • (2003) Journal of Endocrinology , vol.176 , pp. 39-46
    • Singh, R.1    Upadhyay, G.2    Kumar, S.3    Kapoor, A.4    Kumar, A.5    Tiwari, M.6    Godbole, M.M.7
  • 45
    • 0042703137 scopus 로고    scopus 로고
    • Particulate matter induces alveolar epithelial cell DNA damage and apoptosis: role of free radicals and the mitochondria
    • Upadhyay D., Panduri V., Ghio A., Kamp D.W. Particulate matter induces alveolar epithelial cell DNA damage and apoptosis: role of free radicals and the mitochondria. American Journal of Respiratory Cell and Molecular Biology 2003, 29:180-187.
    • (2003) American Journal of Respiratory Cell and Molecular Biology , vol.29 , pp. 180-187
    • Upadhyay, D.1    Panduri, V.2    Ghio, A.3    Kamp, D.W.4
  • 47
    • 36949031083 scopus 로고    scopus 로고
    • Effects of exercise on NMDA receptor subunit contributions to bidirectional synaptic plasticity in the mouse dentate gyrus
    • Vasuta C., Caunt C., James R., Samadi S., Schibuk E., Kannangara T., Titterness A.K., Christie B.R. Effects of exercise on NMDA receptor subunit contributions to bidirectional synaptic plasticity in the mouse dentate gyrus. Hippocampus 2007, 17:1201-1208.
    • (2007) Hippocampus , vol.17 , pp. 1201-1208
    • Vasuta, C.1    Caunt, C.2    James, R.3    Samadi, S.4    Schibuk, E.5    Kannangara, T.6    Titterness, A.K.7    Christie, B.R.8
  • 48
    • 9644270414 scopus 로고    scopus 로고
    • Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition
    • Vaynman S., Ying Z., Gomez-Pinilla F. Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition. European Journal of Neuroscience 2004, 20:2580-2590.
    • (2004) European Journal of Neuroscience , vol.20 , pp. 2580-2590
    • Vaynman, S.1    Ying, Z.2    Gomez-Pinilla, F.3
  • 49
    • 64449084958 scopus 로고    scopus 로고
    • Effects of postnatal thyroid hormone deficiency on neurogenesis in the juvenile and adult rat
    • Zhang L., Blomgren K., Kuhn H.G., Cooper-Kuhn C.M. Effects of postnatal thyroid hormone deficiency on neurogenesis in the juvenile and adult rat. Neurobiology of Disease 2009, 34:366-374.
    • (2009) Neurobiology of Disease , vol.34 , pp. 366-374
    • Zhang, L.1    Blomgren, K.2    Kuhn, H.G.3    Cooper-Kuhn, C.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.