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Volumn 7, Issue 1, 2013, Pages 237-241

CD8+ T cells from vitiligo perilesional margins induce autologous melanocyte apoptosis

Author keywords

CD8+ T cells; Cytokine; Melanocytes; Vitiligo

Indexed keywords

CD137 ANTIGEN; CD69 ANTIGEN; INTERLEUKIN 13; INTERLEUKIN 6;

EID: 84873867929     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2012.1117     Document Type: Article
Times cited : (76)

References (36)
  • 1
    • 0034606276 scopus 로고    scopus 로고
    • Melanocyte destruction after antigen-specific immunotherapy of melanoma: Direct evidence of T cell-mediated vitiligo
    • Yee C, Thompson JA, Roche P, et al: Melanocyte destruction after antigen-specific immunotherapy of melanoma: direct evidence of T cell-mediated vitiligo. J Exp Med 192:1637-44, 2000.
    • (2000) J Exp Med , vol.192 , pp. 1637-1644
    • Yee, C.1    Thompson, J.A.2    Roche, P.3
  • 2
    • 0036221334 scopus 로고    scopus 로고
    • The melanin-concentrating hormone receptor 1, a novel target of autoantibody responses in vitiligo
    • Kemp EH, Waterman EA, Hawes BE, et al: The melanin-concentrating hormone receptor 1, a novel target of autoantibody responses in vitiligo. J Clin Invest 109: 923-930, 2002.
    • (2002) J Clin Invest , vol.109 , pp. 923-930
    • Kemp, E.H.1    Waterman, E.A.2    Hawes, B.E.3
  • 3
    • 0035721929 scopus 로고    scopus 로고
    • Specific cytotoxic T lymphocyte responses against Melan-A/MART1, tyrosinase and gp100 in vitiligo by the use of major histocompatibility complex/peptide tetramers: The role of cellular immunity in the etiopathogenesis of vitiligo
    • Palermo B, Campanelli R, Garbelli S, et al: Specific cytotoxic T lymphocyte responses against Melan-A/MART1, tyrosinase and gp100 in vitiligo by the use of major histocompatibility complex/peptide tetramers: the role of cellular immunity in the etiopathogenesis of vitiligo. J Invest Dermatol 117: 326-332, 2001.
    • (2001) J Invest Dermatol , vol.117 , pp. 326-332
    • Palermo, B.1    Campanelli, R.2    Garbelli, S.3
  • 4
    • 78751617257 scopus 로고    scopus 로고
    • Vitiligo, reactive oxygen species and T-cells (Review)
    • Glassman SJ: Vitiligo, reactive oxygen species and T-cells (Review). Clin Sci (Lond) 120: 99-120, 2011
    • (2011) Clin Sci (Lond) , vol.120 , pp. 99-120
    • Glassman, S.J.1
  • 5
    • 38349019277 scopus 로고    scopus 로고
    • Autoimmune etiology of generalized vitiligo (Review)
    • Le Poole IC and Luiten RM: Autoimmune etiology of generalized vitiligo (Review). Curr Dir Autoimmun 10: 227-243, 2008.
    • (2008) Curr Dir Autoimmun , vol.10 , pp. 227-243
    • Le Poole, I.C.1    Luiten, R.M.2
  • 6
    • 43349087382 scopus 로고    scopus 로고
    • Langerhans cells and dendritic cells are cytotoxic towards HPV16 E6 and E7 expressing target cells
    • Le Poole IC, ElMasri WM, Denman CJ, et al: Langerhans cells and dendritic cells are cytotoxic towards HPV16 E6 and E7 expressing target cells. Cancer Immunol Immunother 57: 789-797, 2008
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 789-797
    • Le Poole, I.C.1    Elmasri, W.M.2    Denman, C.J.3
  • 7
    • 0037648525 scopus 로고    scopus 로고
    • Evidence for an autoimmune pathogenesis of vitiligo (Review)
    • Ongenae K, Van Geel N and Naeyaert JM: Evidence for an autoimmune pathogenesis of vitiligo (Review). Pigment Cell Res 16: 90-100, 2003.
    • (2003) Pigment Cell Res , vol.16 , pp. 90-100
    • Ongenae, K.1    Van Geel, N.2    Naeyaert, J.M.3
  • 8
    • 0027319578 scopus 로고
    • An immunohistological study of cutaneous lymphocytes in vitiligo
    • Badri AM, Todd PM, Garioch JJ, et al: An immunohistological study of cutaneous lymphocytes in vitiligo. J Pathol 170: 149-155, 1993.
    • (1993) J Pathol , vol.170 , pp. 149-155
    • Badri, A.M.1    Todd, P.M.2    Garioch, J.J.3
  • 10
    • 0037902609 scopus 로고    scopus 로고
    • Melanocyte-specific immune response in melanoma and vitiligo: Two faces of the same coin?
    • Wankowicz-Kalinska A, Le Poole C, van den Wijngaard R, et al: Melanocyte-specific immune response in melanoma and vitiligo: two faces of the same coin? Pigment Cell Res 16: 254-260, 2003.
    • (2003) Pigment Cell Res , vol.16 , pp. 254-260
    • Wankowicz-Kalinska, A.1    Le Poole, C.2    Van Den-Wijngaard, R.3
  • 11
    • 0033805448 scopus 로고    scopus 로고
    • Expression and modulation of apoptosis regulatory molecules in human melanocytes: Significance in vitiligo
    • van den Wijngaard RM, Aten J, Scheepmaker A, et al: Expression and modulation of apoptosis regulatory molecules in human melanocytes: significance in vitiligo. Br J Dermatol 143: 573-581, 2000.
    • (2000) Br J Dermatol , vol.143 , pp. 573-581
    • Van Den-Wijngaard, R.M.1    Aten, J.2    Scheepmaker, A.3
  • 12
    • 0033889236 scopus 로고    scopus 로고
    • Local immune response in skin of generalized vitiligo patients. Destruction of melanocytes is associated with the prominent presence of CLA+ T cells at the perilesional site
    • van den Wijngaard R, Wankowicz-Kalinska A, Le Poole C, et al: Local immune response in skin of generalized vitiligo patients. Destruction of melanocytes is associated with the prominent presence of CLA+ T cells at the perilesional site. Lab Invest 80: 1299-1309, 2000.
    • (2000) Lab Invest , vol.80 , pp. 1299-1309
    • Van Den-Wijngaard, R.1    Wankowicz-Kalinska, A.2    Le Poole, C.3
  • 13
    • 0023266489 scopus 로고
    • The skin immune system (SIS): Distribution and immunophenotype of lymphocyte subpopulations in normal human skin
    • Bos JD, Zonneveld I, Das PK, et al: The skin immune system (SIS): distribution and immunophenotype of lymphocyte subpopulations in normal human skin. J Invest Dermatol 88: 569-573, 1987.
    • (1987) J Invest Dermatol , vol.88 , pp. 569-573
    • Bos, J.D.1    Zonneveld, I.2    Das, P.K.3
  • 14
    • 0023552087 scopus 로고
    • Sample size determination in clinical trials with an emphasis on exponentially distributed responses
    • Gross AJ, Hunt HH, Cantor AB and Clark BC: Sample size determination in clinical trials with an emphasis on exponentially distributed responses. Biometrics 43: 875-883, 1987.
    • (1987) Biometrics , vol.43 , pp. 875-883
    • Gross, A.J.1    Hunt, H.H.2    Cantor, A.B.3    Clark, B.C.4
  • 15
    • 70349731750 scopus 로고    scopus 로고
    • Autoimmune destruction of skin melanocytes by perilesional T cells from vitiligo patients
    • van den Boorn JG, Konijnenberg D, Dellemijn TA, et al: Autoimmune destruction of skin melanocytes by perilesional T cells from vitiligo patients. J Invest Dermatol 129: 2220-2232, 2009.
    • (2009) J Invest Dermatol , vol.129 , pp. 2220-2232
    • Van Den-Boorn, J.G.1    Konijnenberg, D.2    Dellemijn, T.A.3
  • 16
    • 79954580876 scopus 로고    scopus 로고
    • Treatment of vitiligo in children and adolescents by autologous cultured pure melanocytes transplantation with comparison of efficacy to results in adults
    • Hong WS, Hu DN, Qian GP, et al: Treatment of vitiligo in children and adolescents by autologous cultured pure melanocytes transplantation with comparison of efficacy to results in adults. J Eur Acad Dermatol Venereol 25: 538-543, 2011.
    • (2011) J Eur Acad Dermatol Venereol , vol.25 , pp. 538-543
    • Hong, W.S.1    Hu, D.N.2    Qian, G.P.3
  • 17
    • 80052273929 scopus 로고    scopus 로고
    • Ratio of size of recipient and donor areas in treatment of vitiligo by autologous cultured melanocyte transplantation
    • Hong WS, Hu DN, Qian GP, et al: Ratio of size of recipient and donor areas in treatment of vitiligo by autologous cultured melanocyte transplantation. Br J Dermatol 165: 520-525, 2011.
    • (2011) Br J Dermatol , vol.165 , pp. 520-525
    • Hong, W.S.1    Hu, D.N.2    Qian, G.P.3
  • 18
    • 85052661690 scopus 로고    scopus 로고
    • Alterations in IL-6, IL-8, GM-CSF, TNF-alpha, and IFN-gamma release by peripheral mononuclear cells in patients with active vitiligo
    • Yu HS, Chang KL, Yu CL, et al: Alterations in IL-6, IL-8, GM-CSF, TNF-alpha, and IFN-gamma release by peripheral mononuclear cells in patients with active vitiligo. J Invest Dermatol 108: 527-529, 1997.
    • (1997) J Invest Dermatol , vol.108 , pp. 527-529
    • Yu, H.S.1    Chang, K.L.2    Yu, C.L.3
  • 19
    • 0036098164 scopus 로고    scopus 로고
    • New insights into the pathogenesis of vitiligo: Imbalance of epidermal cytokines at sites of lesions
    • Moretti S, Spallanzani A, Amato L, et al: New insights into the pathogenesis of vitiligo: imbalance of epidermal cytokines at sites of lesions. Pigment Cell Res 15: 87-92, 2002.
    • (2002) Pigment Cell Res , vol.15 , pp. 87-92
    • Moretti, S.1    Spallanzani, A.2    Amato, L.3
  • 20
    • 0036169289 scopus 로고    scopus 로고
    • Vitiligo and epidermal microenvironment: Possible involvement of keratinocyte-derived cytokines
    • Moretti S, Spallanzani A, Amato L, et al: Vitiligo and epidermal microenvironment: possible involvement of keratinocyte-derived cytokines. Arch Dermatol 138: 273-274, 2002.
    • (2002) Arch Dermatol , vol.138 , pp. 273-274
    • Moretti, S.1    Spallanzani, A.2    Amato, L.3
  • 21
    • 0037291793 scopus 로고    scopus 로고
    • Increased interleukin-6 and granulocyte-macrophage colony stimulating factor levels in the sera of patients with non-segmental vitiligo
    • Tu CX, Gu JS and Lin XR: Increased interleukin-6 and granulocyte- macrophage colony stimulating factor levels in the sera of patients with non-segmental vitiligo. J Dermatol Sci 31: 73-78, 2003.
    • (2003) J Dermatol Sci , vol.31 , pp. 73-78
    • Tu, C.X.1    Gu, J.S.2    Lin, X.R.3
  • 22
    • 79957673711 scopus 로고    scopus 로고
    • IL-6 signaling in autoimmunity, chronic inflammation and inflammation-associated cancer (Review)
    • Neurath MF and Finotto S: IL-6 signaling in autoimmunity, chronic inflammation and inflammation-associated cancer (Review). Cytokine Growth Factor Rev 22: 83-89, 2011.
    • (2011) Cytokine Growth Factor Rev , vol.22 , pp. 83-89
    • Neurath, M.F.1    Finotto, S.2
  • 23
    • 79955470407 scopus 로고    scopus 로고
    • The soluble Interleukin 6 receptor: Generation and role in inflammation and cancer
    • Chalaris A, Garbers C, Rabe B, et al: The soluble Interleukin 6 receptor: generation and role in inflammation and cancer. Eur J Cell Biol 90: 484-494, 2011.
    • (2011) Eur J Cell Biol , vol.90 , pp. 484-494
    • Chalaris, A.1    Garbers, C.2    Rabe, B.3
  • 24
    • 0028881286 scopus 로고
    • Cutaneous metastatic angiosarcoma with a lethal outcome, following radiotherapy for a cervical carcinoma
    • Krasagakis K, Hettmannsperger U, Tebbe B and Garbe C: Cutaneous metastatic angiosarcoma with a lethal outcome, following radiotherapy for a cervical carcinoma. Br J Dermatol 133: 610-614, 1995.
    • (1995) Br J Dermatol , vol.133 , pp. 610-614
    • Krasagakis, K.1    Hettmannsperger, U.2    Tebbe, B.3    Garbe, C.4
  • 26
    • 0028939204 scopus 로고
    • Tumour necrosis factors and several interleukins inhibit the growth and modulate the antigen expression of normal human melanocytes in vitro
    • Krasagakis K, Garbe C, Eberle J and Orfanos CE: Tumour necrosis factors and several interleukins inhibit the growth and modulate the antigen expression of normal human melanocytes in vitro. Arch Dermatol Res 287: 259-265, 1995.
    • (1995) Arch Dermatol Res , vol.287 , pp. 259-265
    • Krasagakis, K.1    Garbe, C.2    Eberle, J.3    Orfanos, C.E.4
  • 27
    • 84862830762 scopus 로고    scopus 로고
    • Dysregulation of melanocyte function by Th17-related cytokines: Significance of Th17 cell infiltration in autoimmune vitiligo vulgaris
    • Kotobuki Y, Tanemura A, Yang L, et al: Dysregulation of melanocyte function by Th17-related cytokines: significance of Th17 cell infiltration in autoimmune vitiligo vulgaris. Pigment Cell Melanoma Res 25: 219-230, 2012.
    • (2012) Pigment Cell Melanoma Res , vol.25 , pp. 219-230
    • Kotobuki, Y.1    Tanemura, A.2    Yang, L.3
  • 28
    • 57149107119 scopus 로고    scopus 로고
    • The effects of IL-6 on CD4 T cell responses (Review)
    • Dienz O and Rincon M: The effects of IL-6 on CD4 T cell responses (Review). Clin Immunol 130: 27-33, 2009.
    • (2009) Clin Immunol , vol.130 , pp. 27-33
    • Dienz, O.1    Rincon, M.2
  • 30
    • 77951192680 scopus 로고    scopus 로고
    • Anti-IL-6 receptor antibody suppressed T cell activation by inhibiting IL-2 production and inducing regulatory T cells
    • Yoshida H, Hashizume M, Suzuki M and Mihara M: Anti-IL-6 receptor antibody suppressed T cell activation by inhibiting IL-2 production and inducing regulatory T cells. Eur J Pharmacol 634: 178-183, 2010.
    • (2010) Eur J Pharmacol , vol.634 , pp. 178-183
    • Yoshida, H.1    Hashizume, M.2    Suzuki, M.3    Mihara, M.4
  • 31
    • 78751572960 scopus 로고    scopus 로고
    • IL-6 blockade preferentially inhibits Th17 differentiation in collagen-induced arthritis
    • Yoshida H, Hashizume M and Mihara M: IL-6 blockade preferentially inhibits Th17 differentiation in collagen-induced arthritis. Rheumatol Int 31: 127-131, 2011.
    • (2011) Rheumatol Int , vol.31 , pp. 127-131
    • Yoshida, H.1    Hashizume, M.2    Mihara, M.3
  • 32
    • 70350376860 scopus 로고    scopus 로고
    • Properties and origin of human Th17 cells (Review)
    • Romagnani S, Maggi E, Liotta F, et al: Properties and origin of human Th17 cells (Review). Mol Immunol 47: 3-7, 2009.
    • (2009) Mol Immunol , vol.47 , pp. 3-7
    • Romagnani, S.1    Maggi, E.2    Liotta, F.3
  • 33
    • 0032193220 scopus 로고    scopus 로고
    • Essential roles of Lyn in fibronectin-mediated filamentous actin assembly and cell motility in mast cells
    • Suzuki T, Shoji S, Yamamoto K, et al: Essential roles of Lyn in fibronectin-mediated filamentous actin assembly and cell motility in mast cells. J Immunol 161: 3694-3701, 1998.
    • (1998) J Immunol , vol.161 , pp. 3694-3701
    • Suzuki, T.1    Shoji, S.2    Yamamoto, K.3
  • 34
    • 0036772222 scopus 로고    scopus 로고
    • Genetics of IL-13 and functional relevance of IL-13 variants (Review)
    • Vercelli D: Genetics of IL-13 and functional relevance of IL-13 variants (Review). Curr Opin Allergy Clin Immunol 2: 389-393, 2002.
    • (2002) Curr Opin Allergy Clin Immunol , vol.2 , pp. 389-393
    • Vercelli, D.1
  • 35
    • 9644268915 scopus 로고    scopus 로고
    • Opposing roles for IL-13 and IL-13 receptor alpha 2 in health and disease (Review)
    • Mentink-Kane MM and Wynn TA: Opposing roles for IL-13 and IL-13 receptor alpha 2 in health and disease (Review). Immunol Rev 202: 191-202, 2004.
    • (2004) Immunol Rev , vol.202 , pp. 191-202
    • Mentink-Kane, M.M.1    Wynn, T.A.2
  • 36
    • 9144219618 scopus 로고    scopus 로고
    • IL-13 receptor alpha 2 down-modulates granulomatous inflammation and prolongs host survival in schistosomiasis
    • Mentink-Kane MM, Cheever AW, Thompson RW, et al: IL-13 receptor alpha 2 down-modulates granulomatous inflammation and prolongs host survival in schistosomiasis. Proc Natl Acad Sci USA 101: 586-590, 2004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 586-590
    • Mentink-Kane, M.M.1    Cheever, A.W.2    Thompson, R.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.