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Volumn 7, Issue 2, 2013, Pages 603-607

Analysis of critical molecules and signaling pathways in osteoarthritis and rheumatoid arthritis

Author keywords

Osteoarthritis; Rheumatoid arthritis; Signaling pathways

Indexed keywords

ALSTERPAULLONE; COLLAGEN TYPE 2; IMMUNOGLOBULIN A; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; PARTHENOLIDE; SOMATOMEDIN C;

EID: 84873863868     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2012.1224     Document Type: Article
Times cited : (18)

References (38)
  • 1
    • 49449104156 scopus 로고    scopus 로고
    • The complex pathology of osteoarthritis: Even mitochondria are involved
    • Roach HI: The complex pathology of osteoarthritis: even mitochondria are involved. Arthritis Rheum 58: 2217-2218, 2008.
    • (2008) Arthritis Rheum , vol.58 , pp. 2217-2218
    • Roach, H.I.1
  • 2
    • 54249161395 scopus 로고    scopus 로고
    • New horizons and perspectives in the treatment of osteoarthritis
    • Berenbaum F: New horizons and perspectives in the treatment of osteoarthritis. Arthritis Res Ther 10 (Suppl 2): S1, 2008.
    • (2008) Arthritis Res Ther , vol.10 , Issue.SUPPL. 2
    • Berenbaum, F.1
  • 3
    • 38949129354 scopus 로고    scopus 로고
    • Osteoarthritis of the knee in primary care
    • Dieppe P: Osteoarthritis of the knee in primary care. BMJ 336: 105-106, 2008.
    • (2008) BMJ , vol.336 , pp. 105-106
    • Dieppe, P.1
  • 4
    • 0027408063 scopus 로고
    • Molecular and cellular mechanisms of joint destruction in rheumatoid arthritis: Two cellular mechanisms explain joint destruction?
    • Gay S, Gay RE and Koopman WJ: Molecular and cellular mechanisms of joint destruction in rheumatoid arthritis: two cellular mechanisms explain joint destruction? Ann Rheum Dis 52 (Suppl 1): S39-S47, 1993.
    • (1993) Ann Rheum Dis , vol.52 , Issue.SUPPL. 1
    • Gay, S.1    Gay, R.E.2    Koopman, W.J.3
  • 5
    • 1442352158 scopus 로고    scopus 로고
    • Epidemiology and burden of illness of rheumatoid arthritis
    • Kvien TK: Epidemiology and burden of illness of rheumatoid arthritis. Pharmacoeconomics 22: 1-12, 2004.
    • (2004) Pharmacoeconomics , vol.22 , pp. 1-12
    • Kvien, T.K.1
  • 6
    • 84859869492 scopus 로고    scopus 로고
    • Osteoarthritis and rheumatoid arthritis: Conservative therapeutic management
    • Beasley J: Osteoarthritis and rheumatoid arthritis: conservative therapeutic management. J Hand Ther 25: 163-171, 2012.
    • (2012) J Hand Ther , vol.25 , pp. 163-171
    • Beasley, J.1
  • 7
    • 39449134583 scopus 로고    scopus 로고
    • The role of specialists in managing established rheumatoid arthritis
    • Scott DL and Symmons DP: The role of specialists in managing established rheumatoid arthritis. Rheumatology (Oxford) 47: 237-238, 2008.
    • (2008) Rheumatology (Oxford) , vol.47 , pp. 237-238
    • Scott, D.L.1    Symmons, D.P.2
  • 8
    • 84863237736 scopus 로고    scopus 로고
    • Decoding the differential biomarkers of Rheumatoid arthritis and Osteoarthritis: A functional genomics paradigm to design disease specific therapeutics
    • Biswas S, Manikandan J and Pushparaj PN: Decoding the differential biomarkers of Rheumatoid arthritis and Osteoarthritis: A functional genomics paradigm to design disease specific therapeutics. Bioinformation 6: 153-157, 2011.
    • (2011) Bioinformation , vol.6 , pp. 153-157
    • Biswas, S.1    Manikandan, J.2    Pushparaj, P.N.3
  • 9
    • 78649728802 scopus 로고    scopus 로고
    • Molecular signatures and new candidates to target the pathogenesis of rheumatoid arthritis
    • Ungethuem U, Haeupl T, Witt H, et al: Molecular signatures and new candidates to target the pathogenesis of rheumatoid arthritis. Physiol Genomics 42A: 267-282, 2010.
    • (2010) Physiol Genomics , vol.42 A , pp. 267-282
    • Ungethuem, U.1    Haeupl, T.2    Witt, H.3
  • 10
    • 0142121516 scopus 로고    scopus 로고
    • Exploration, normalization and summaries of high density oligonucleotide array probe level data
    • Irizarry RA, Hobbs B, Collin F, et al: Exploration, normalization and summaries of high density oligonucleotide array probe level data. Biostatistics 4: 249-264, 2003.
    • (2003) Biostatistics , vol.4 , pp. 249-264
    • Irizarry, R.A.1    Hobbs, B.2    Collin, F.3
  • 11
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • Smyth GK: Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 3: 3, 2004.
    • (2004) Stat Appl Genet Mol Biol , vol.3 , pp. 3
    • Smyth, G.K.1
  • 12
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini Y and Hochberg Y: Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Series B Stat Methodol 57: 289-300, 1995.
    • (1995) J R Stat Soc Series B Stat Methodol , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 13
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang DW, Sherman BT and Lempicki RA: Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4: 44-57, 2009.
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 14
    • 58549112996 scopus 로고    scopus 로고
    • Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
    • Huang da W, Sherman BT and Lempicki RA: Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 37: 1-13, 2009.
    • (2009) Nucleic Acids Res , vol.37 , pp. 1-13
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 15
    • 33749335282 scopus 로고    scopus 로고
    • The connectivity map: Using gene-expression signatures to connect small molecules, genes and disease
    • Lamb J, Crawford ED, Peck D, et al: The connectivity map: using gene-expression signatures to connect small molecules, genes and disease. Science 313: 1929-1935, 2006.
    • (2006) Science , vol.313 , pp. 1929-1935
    • Lamb, J.1    Crawford, E.D.2    Peck, D.3
  • 16
    • 76549091830 scopus 로고    scopus 로고
    • MAPKs are essential upstream signaling pathways in proteolytic cartilage degradation-divergence in pathways leading to aggrecanase and MMP-mediated articular cartilage degradation
    • Sondergaard BC, Schultz N, Madsen SH, Bay-Jensen AC, Kassem M and Karsdal MA: MAPKs are essential upstream signaling pathways in proteolytic cartilage degradation-divergence in pathways leading to aggrecanase and MMP-mediated articular cartilage degradation. Osteoarthritis Cartilage 18: 279-288, 2010.
    • (2010) Osteoarthritis Cartilage , vol.18 , pp. 279-288
    • Sondergaard, B.C.1    Schultz, N.2    Madsen, S.H.3    Bay-Jensen, A.C.4    Kassem, M.5    Karsdal, M.A.6
  • 17
    • 41849088475 scopus 로고    scopus 로고
    • The roles of MAPKs in disease
    • Lawrence MC, Jivan A, Shao C, et al: The roles of MAPKs in disease. Cell Res 18: 436-442, 2008.
    • (2008) Cell Res , vol.18 , pp. 436-442
    • Lawrence, M.C.1    Jivan, A.2    Shao, C.3
  • 18
    • 0033151897 scopus 로고    scopus 로고
    • ICAM-2 and a peptide from its binding domain are efficient activators of leukocyte adhesion and integrin affinity
    • Kotovuori A, Pessa-Morikawa T, Kotovuori P, Nortamo P and Gahmberg CG: ICAM-2 and a peptide from its binding domain are efficient activators of leukocyte adhesion and integrin affinity. J Immunol 162: 6613-6620, 1999.
    • (1999) J Immunol , vol.162 , pp. 6613-6620
    • Kotovuori, A.1    Pessa-Morikawa, T.2    Kotovuori, P.3    Nortamo, P.4    Gahmberg, C.G.5
  • 19
    • 0025049129 scopus 로고
    • Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatases expressed in brain
    • Kaplan R, Morse B, Huebner K, et al: Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine- phosphatases expressed in brain. Proc Natl Acad Sci U S A 87: 7000-7004, 1990.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 7000-7004
    • Kaplan, R.1    Morse, B.2    Huebner, K.3
  • 20
  • 21
    • 0028074376 scopus 로고
    • Characterization of a new member of the human beta-adaptin gene family from chromosome 22q12, a candidate meningioma gene
    • Peyrard M, Fransson I, Xie YG, et al: Characterization of a new member of the human beta-adaptin gene family from chromosome 22q12, a candidate meningioma gene. Hum Mol Genet 3: 1393-1399, 1994.
    • (1994) Hum Mol Genet , vol.3 , pp. 1393-1399
    • Peyrard, M.1    Fransson, I.2    Xie, Y.G.3
  • 23
    • 0028579773 scopus 로고
    • Autoimmune thyroid disease: Further developments in our understanding
    • Weetman AP and McGregor AM: Autoimmune thyroid disease: further developments in our understanding. Endocr Rev 15: 788-830, 1994.
    • (1994) Endocr Rev , vol.15 , pp. 788-830
    • Weetman, A.P.1    McGregor, A.M.2
  • 24
    • 33746848638 scopus 로고    scopus 로고
    • Parthenolide modulates the NF-kappaB-mediated inflammatory responses in experimental atherosclerosis
    • López-Franco O, Hernández-Vargas P, Ortiz-Muñoz G, et al: Parthenolide modulates the NF-kappaB-mediated inflammatory responses in experimental atherosclerosis. Arterioscler Thromb Vasc Biol 26: 1864-1870, 2006.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1864-1870
    • López-Franco, O.1    Hernández-Vargas, P.2    Ortiz-Muñoz, G.3
  • 25
    • 16644376048 scopus 로고    scopus 로고
    • Sesquiterpene lactone parthenolide blocks lipopolysaccharide-induced osteolysis through the suppression of NF-kappaB activity
    • Yip KH, Zheng MH, Feng HT, Steer JH, Joyce DA and Xu J: Sesquiterpene lactone parthenolide blocks lipopolysaccharide-induced osteolysis through the suppression of NF-kappaB activity. J Bone Miner Res 19: 1905-1916, 2004.
    • (2004) J Bone Miner Res , vol.19 , pp. 1905-1916
    • Yip, K.H.1    Zheng, M.H.2    Feng, H.T.3    Steer, J.H.4    Joyce, D.A.5    Xu, J.6
  • 26
    • 16844363378 scopus 로고    scopus 로고
    • The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells
    • Guzman ML, Rossi RM, Karnischky L, et al: The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells. Blood 105: 4163-4169, 2005.
    • (2005) Blood , vol.105 , pp. 4163-4169
    • Guzman, M.L.1    Rossi, R.M.2    Karnischky, L.3
  • 28
    • 11144316081 scopus 로고    scopus 로고
    • Anti-inflammatory and anti-hyperalgesic effects of sesquiterpene lactones from Magnolia and Bear's foot
    • Feltenstein MW, Schuhly W, Warnick JE, Fischer NH and Sufka KJ: Anti-inflammatory and anti-hyperalgesic effects of sesquiterpene lactones from Magnolia and Bear's foot. Pharmacol Biochem Behav 79: 299-302, 2004.
    • (2004) Pharmacol Biochem Behav , vol.79 , pp. 299-302
    • Feltenstein, M.W.1    Schuhly, W.2    Warnick, J.E.3    Fischer, N.H.4    Sufka, K.J.5
  • 29
    • 11244341559 scopus 로고    scopus 로고
    • Antileishmanial activity of parthenolide, a sesquiterpene lactone isolated from Tanacetum parthenium
    • Tiuman TS, Ueda-Nakamura T, Garcia Cortez DA, et al: Antileishmanial activity of parthenolide, a sesquiterpene lactone isolated from Tanacetum parthenium. Antimicrob Agents Chemother 49: 176-182, 2005.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 176-182
    • Tiuman, T.S.1    Ueda-Nakamura, T.2    Garcia Cortez, D.A.3
  • 30
    • 0033798031 scopus 로고    scopus 로고
    • Paullones are potent inhibitors of glycogen synthase kinase-3beta and cyclin-dependent kinase 5/p25
    • Leost M, Schultz C, Link A, et al: Paullones are potent inhibitors of glycogen synthase kinase-3beta and cyclin-dependent kinase 5/p25. Eur J Biochem 267: 5983-5994, 2000.
    • (2000) Eur J Biochem , vol.267 , pp. 5983-5994
    • Leost, M.1    Schultz, C.2    Link, A.3
  • 31
    • 0037387215 scopus 로고    scopus 로고
    • Alsterpaullone, a novel cyclin-dependent kinase inhibitor, induces apoptosis by activation of caspase-9 due to perturbation in mitochondrial membrane potential
    • Lahusen T, De Siervi A, Kunick C and Senderowicz AM: Alsterpaullone, a novel cyclin-dependent kinase inhibitor, induces apoptosis by activation of caspase-9 due to perturbation in mitochondrial membrane potential. Mol Carcinog 36: 183-194, 2003.
    • (2003) Mol Carcinog , vol.36 , pp. 183-194
    • Lahusen, T.1    De Siervi, A.2    Kunick, C.3    Senderowicz, A.M.4
  • 32
    • 0022001611 scopus 로고
    • The human gene encoding insulin-like growth factor i is located on chromosome 12
    • Hoppener JW, de Pagter-Holthuizen P, Geurts van Kessel AH, et al: The human gene encoding insulin-like growth factor I is located on chromosome 12. Hum Genet 69: 157-160, 1985.
    • (1985) Hum Genet , vol.69 , pp. 157-160
    • Hoppener, J.W.1    De Pagter-Holthuizen, P.2    Geurts Van Kessel, A.H.3
  • 33
    • 0021021639 scopus 로고
    • Sequence of cDNA encoding human insulin-like growth factor i precursor
    • Jansen M, van Schaik FM, Ricker AT, et al: Sequence of cDNA encoding human insulin-like growth factor I precursor. Nature 306: 609-611, 1983.
    • (1983) Nature , vol.306 , pp. 609-611
    • Jansen, M.1    Van Schaik, F.M.2    Ricker, A.T.3
  • 34
    • 7744237924 scopus 로고    scopus 로고
    • Nitric oxide decreases IGF-1 receptor function in vitro; Glutathione depletion enhances this effect in vivo
    • Studer RK: Nitric oxide decreases IGF-1 receptor function in vitro; glutathione depletion enhances this effect in vivo. Osteoarthritis Cartilage 12: 863-869, 2004.
    • (2004) Osteoarthritis Cartilage , vol.12 , pp. 863-869
    • Studer, R.K.1
  • 35
    • 0021969544 scopus 로고
    • Regional chromosome mapping of human collagen genes alpha 2(I) and alpha 1(I) (COLIA2 and COLIA1)
    • Retief E, Parker MI and Retief AE: Regional chromosome mapping of human collagen genes alpha 2(I) and alpha 1(I) (COLIA2 and COLIA1). Hum Genet 69: 304-308, 1985.
    • (1985) Hum Genet , vol.69 , pp. 304-308
    • Retief, E.1    Parker, M.I.2    Retief, A.E.3
  • 36
    • 0023935329 scopus 로고
    • Arginine for glycine substitution in the triple-helical domain of the products of one alpha 2(I) collagen allele (COL1A2) produces the osteogenesis imperfecta type IV phenotype
    • Wenstrup RJ, Cohn DH, Cohen T and Byers PH: Arginine for glycine substitution in the triple-helical domain of the products of one alpha 2(I) collagen allele (COL1A2) produces the osteogenesis imperfecta type IV phenotype. J Biol Chem 263: 7734-7740, 1988.
    • (1988) J Biol Chem , vol.263 , pp. 7734-7740
    • Wenstrup, R.J.1    Cohn, D.H.2    Cohen, T.3    Byers, P.H.4
  • 37
    • 0033617742 scopus 로고    scopus 로고
    • Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro
    • Kikuno R, Nagase T, Ishikawa K, et al: Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res 6: 197-205, 1999.
    • (1999) DNA Res , vol.6 , pp. 197-205
    • Kikuno, R.1    Nagase, T.2    Ishikawa, K.3
  • 38
    • 10744227687 scopus 로고    scopus 로고
    • Identification of SATB2 as the cleft palate gene on 2q32-q33
    • Fitz Patrick DR, Carr IM, McLaren L, et al: Identification of SATB2 as the cleft palate gene on 2q32-q33. Hum Mol Genet 12: 2491-2501, 2003.
    • (2003) Hum Mol Genet , vol.12 , pp. 2491-2501
    • Fitz Patrick, D.R.1    Carr, I.M.2    McLaren, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.