Activation of double-stranded rna-activated protein kinase (PKR) by interferon-stimulated gene 15 (ISG15) modification down-regulates protein translation

Journal of Biological Chemistry

Volumn 288, Issue 4, 2013, Pages 2839-2847

  Okumura, Fumihiko ^a   Okumura, Akiko J ^a   Uematsu, Keiji ^a   Hatakeyama, Shigetsugu ^b   Zhang, Dong Er ^c   Kamura, Takumi ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANTIBIOTICS; CHEMICAL ACTIVATION; ENZYMES; GLYCOPROTEINS; VIRUSES;

ACTIVATED PROTEINS; ANTI-VIRAL EFFECTS; DOUBLE-STRANDED RNA; INNATE IMMUNE RESPONSE; PATHOGEN INFECTION; PROTEIN MODIFICATIONS; PROTEIN TRANSLATION; TRANSLATIONAL REGULATION;

IMMUNE SYSTEM;

HYBRID PROTEIN; INITIATION FACTOR 2ALPHA; INTERFERON STIMULATED GENE 15 PROTEIN KINASE R FUSION PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; CONTROLLED STUDY; COVALENT BOND; DOWN REGULATION; ENZYME ACTIVATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; TRANSLATION REGULATION;

EID: 84873863319     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.401851     Document Type: Article

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