Large Domain Motions in Ago Protein Controlled by the Guide DNA-Strand Seed Region Determine the Ago-DNA-mRNA Complex Recognition Process

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Xia, Zhen ^a,b   Huynh, Tien ^a   Ren, Pengyu ^b   Zhou, Ruhong ^a,c  

^a IBM T J WATSON RESEARCH CENTER   (United States)

^b The University of Texas at Austin   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGONAUTE PROTEIN; MESSENGER RNA;

ALPHA HELIX; ARTICLE; BASE MISPAIRING; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DNA DETERMINATION; DNA HELIX; DNA STRAND; GENE DUPLICATION; HETERODUPLEX ANALYSIS; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; PROTEIN CLEAVAGE; PROTEIN DNA INTERACTION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN RNA BINDING; RNA ANALYSIS; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS;

ARGONAUTE PROTEINS; BASE PAIRING; BASE SEQUENCE; DNA; MICRORNAS; MOLECULAR DYNAMICS SIMULATION; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; REPRODUCIBILITY OF RESULTS; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL UNTRANSLATED;

EID: 84873860467     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054620     Document Type: Article

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