Hydrodynamic-based delivery of PTP1B shRNA reduces plasma glucose levels in diabetic mice

Molecular Medicine Reports

Volumn 7, Issue 1, 2013, Pages 211-216

  Vakili, Sanaz ^a   Ebrahimi, Shadi Sadat Seyyed ^a   Sadeghi, Asie ^a   Gorgani Firuzjaee, Sattar ^a   Beigy, Maani ^a   Pasalar, Parvin ^a   Meshkani, Reza ^a,b,c  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Diabetes; Hydrodynamic tail vein injection; Liver specific knockdown; Protein tyrosine phosphatase 1B; RNA interference

Indexed keywords

FIREFLY LUCIFERASE; GLUCOSE; PROTEIN KINASE B; PROTEIN TYROSINE PHOSPHATASE 1B; SHORT HAIRPIN RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLS; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE OVEREXPRESSION; GENE SILENCING; GLUCOSE BLOOD LEVEL; HYDRODYNAMICS BASED TRANSFECTION; LIVER CELL; MALE; MOUSE; NONHUMAN; PLASMID; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; GENE TRANSFER TECHNIQUES; INJECTIONS, INTRAVENOUS; INSULIN; LIPIDS; LIVER; MALE; ORGAN SPECIFICITY; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84873850650     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2012.1172     Document Type: Article

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