Stimulation of superficial zone protein accumulation by hedgehog and Wnt signaling in surface zone bovine articular chondrocytes

Arthritis and Rheumatism

Volumn 65, Issue 2, 2013, Pages 408-417

  Iwakura, Takashi ^a   Inui, Atsuyuki ^a   Reddi, A Hari ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; 2 (3 CHLORO 4 HYDROXYANILINO) 3 (2 NITROPHENYL)MALEIMIDE; BETA CATENIN; CYCLOPAMINE; GLYCOGEN SYNTHASE KINASE 3BETA; LITHIUM CHLORIDE; SONIC HEDGEHOG PROTEIN; SUPERFICIAL ZONE PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; WNT PROTEIN; WNT11 PROTEIN; WNT3A PROTEIN; WNT5A PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CONTROLLED STUDY; CULTURE MEDIUM; EXPLANT; NONHUMAN; PRIORITY JOURNAL; WNT SIGNALING PATHWAY;

ANIMALS; CARTILAGE, ARTICULAR; CATTLE; CHONDROCYTES; HEDGEHOG PROTEINS; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEINS;

EID: 84873831777     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.37768     Document Type: Article

References (50)

1. Jay GD, Tantravahi U, Britt DE, Barrach HJ, Cha CJ,. Homology of lubricin and superficial zone protein (SZP): products of megakaryocyte stimulating factor (MSF) gene expression by human synovial fibroblasts and articular chondrocytes localized to chromosome 1q25. J Orthop Res 2001; 19: 677-87.
2. Ikegawa S, Sano M, Koshizuka Y, Nakamura Y,. Isolation, characterization and mapping of the mouse and human PRG4 (proteoglycan 4) genes. Cytogenet Cell Genet 2000; 90: 291-7.
3. Schumacher BL, Block JA, Schmid TM, Aydelotte MB, Kuettner KE,. A novel proteoglycan synthesized and secreted by chondrocytes of the superficial zone of articular cartilage. Arch Biochem Biophys 1994; 311: 144-52.
4. Schumacher BL, Hughes CE, Kuettner KE, Caterson B, Aydelotte MB,. Immunodetection and partial cDNA sequence of the proteoglycan, superficial zone protein, synthesized by cells lining synovial joints. J Orthop Res 1999; 17: 110-20.
5. Khalafi A, Schmid TM, Neu C, Reddi AH,. Increased accumulation of superficial zone protein (SZP) in articular cartilage in response to bone morphogenetic protein-7 and growth factors. J Orthop Res 2007; 25: 293-303.
6. Niikura T, Reddi AH,. Differential regulation of lubricin/superficial zone protein by transforming growth factor β/bone morphogenetic protein superfamily members in articular chondrocytes and synoviocytes. Arthritis Rheum 2007; 56: 2312-21.
7. Jay GD, Lane BP, Sokoloff L,. Characterization of a bovine synovial fluid lubricating factor. III. The interaction with hyaluronic acid. Connect Tissue Res 1992; 28: 245-55.
8. Swann DA, Hendren RB, Radin EL, Sotman SL, Duda EA,. The lubricating activity of synovial fluid glycoproteins. Arthritis Rheum 1981; 24: 22-30.
9. Neu CP, Khalafi A, Komvopoulos K, Schmid TM, Reddi AH,. Mechanotransduction of bovine articular cartilage superficial zone protein by transforming growth factor β signaling. Arthritis Rheum 2007; 56: 3706-14.
10. Flannery CR, Hughes CE, Schumacher BL, Tudor D, Aydelotte MB, Kuettner KE, et al. Articular cartilage superficial zone protein (SZP) is homologous to megakaryocyte stimulating factor precursor and is a multifunctional proteoglycan with potential growth-promoting, cytoprotective, and lubricating properties in cartilage metabolism. Biochem Biophys Res Commun 1999; 254: 535-41.
11. Bahabri SA, Suwairi WM, Laxer RM, Polinkovsky A, Dalaan AA, Warman ML,. The camptodactyly-arthropathy-coxa vara- pericarditis syndrome: clinical features and genetic mapping to human chromosome 1. Arthritis Rheum 1998; 41: 730-5.
12. Marcelino J, Carpten JD, Suwairi WM, Gutierrez OM, Schwartz S, Robbins C, et al. CACP, encoding a secreted proteoglycan, is mutated in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Nat Genet 1999; 23: 319-22.
13. Rhee DK, Marcelino J, Baker M, Gong Y, Smits P, Lefebvre V, et al. The secreted glycoprotein lubricin protects cartilage surfaces and inhibits synovial cell overgrowth. J Clin Invest 2005; 115: 622-31.
14. Young AA, McLennan S, Smith MM, Smith SM, Cake MA, Read RA, et al. Proteoglycan 4 downregulation in a sheep meniscectomy model of early osteoarthritis. Arthritis Res Ther 2006; 8: R41.
15. Elsaid KA, Jay GD, Chichester CO,. Reduced expression and proteolytic susceptibility of lubricin/superficial zone protein may explain early elevation in the coefficient of friction in the joints of rats with antigen-induced arthritis. Arthritis Rheum 2007; 56: 108-16.
16. Schmidt TA, Gastelum NS, Han EH, Nugent-Derfus GE, Schumacher BL, Sah RL,. Differential regulation of proteoglycan 4 metabolism in cartilage by IL-1α, IGF-I, and TGF-β1. Osteoarthritis Cartilage 2008; 16: 90-7.
17. Yates KE, Shortkroff S, Reish RG,. Wnt influence on chondrocyte differentiation and cartilage function. DNA Cell Biol 2005; 24: 446-57.
18. Logan CY, Nusse R,. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 2004; 20: 781-810.
19. Lin AC, Seeto BL, Bartoszko JM, Khoury MA, Whetstone H, Ho L, et al. Modulating hedgehog signaling can attenuate the severity of osteoarthritis. Nat Med 2009; 15: 1421-5.
20. Van Amerongen R, Nusse R,. Towards an integrated view of Wnt signaling in development. Development 2009; 136: 3205-14.
21. Mak KK, Chen MH, Day TF, Chuang PT, Yang Y,. Wnt/β-catenin signaling interacts differentially with Ihh signaling in controlling endochondral bone and synovial joint formation. Development 2006; 133: 3695-707.
22. Ehlen HW, Buelens LA, Vortkamp A,. Hedgehog signaling in skeletal development. Birth Defects Res C Embryo Today 2006; 78: 267-79.
23. Spater D, Hill TP, O'Sullivan RJ, Gruber M, Conner DA, Hartmann C,. Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis. Development 2006; 133: 3039-49.
24. Hartmann C, Tabin CJ,. Wnt-14 plays a pivotal role in inducing synovial joint formation in the developing appendicular skeleton. Cell 2001; 104: 341-51.
25. Guo X, Day TF, Jiang X, Garrett-Beal L, Topol L, Yang Y,. Wnt/β-catenin signaling is sufficient and necessary for synovial joint formation. Genes Dev 2004; 18: 2404-17.
26. Chun JS, Oh H, Yang S, Park M,. Wnt signaling in cartilage development and degeneration. BMB Rep 2008; 41: 485-94.
27. Nusslein-Volhard C, Wieschaus E,. Mutations affecting segment number and polarity in Drosophila. Nature 1980; 287: 795-801.
28. Vortkamp A, Lee K, Lanske B, Segre GV, Kronenberg HM, Tabin CJ,. Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein. Science 1996; 273: 613-22.
29. Karp SJ, Schipani E, St-Jacques B, Hunzelman J, Kronenberg H, McMahon AP,. Indian hedgehog coordinates endochondral bone growth and morphogenesis via parathyroid hormone related-protein-dependent and -independent pathways. Development 2000; 127: 543-8.
30. Zhang XM, Ramalho-Santos M, McMahon AP,. Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R asymmetry by the mouse node. Cell 2001; 105: 781-92.
31. Hinck L, Nelson WJ, Papkoff J,. Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing β-catenin binding to the cell adhesion protein cadherin. J Cell Biol 1994; 124: 729-41.
32. Nusse R, Brown A, Papkoff J, Scambler P, Shackleford G, McMahon A, et al. A new nomenclature for int-1 and related genes: the Wnt gene family. Cell 1991; 64: 231.
33. Rijsewijk F, Schuermann M, Wagenaar E, Parren P, Weigel D, Nusse R,. The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless. Cell 1987; 50: 649-57.
34. Shimizu H, Julius MA, Giarre M, Zheng Z, Brown AM, Kitajewski J,. Transformation by Wnt family proteins correlates with regulation of β-catenin. Cell Growth Differ 1997; 8: 1349-58.
35. Molenaar M, van de Wetering M, Oosterwegel M, Peterson-Maduro J, Godsave S, Korinek V, et al. XTcf-3 transcription factor mediates β-catenin-induced axis formation in Xenopus embryos. Cell 1996; 86: 391-9.
36. Semenov MV, Habas R, Macdonald BT, He X,. Noncanonical Wnt signaling pathways. Cell 2007; 131: 1378.
37. Ge X, Ma X, Meng J, Zhang C, Ma K, Zhou C,. Role of Wnt-5A in interleukin-1β-induced matrix metalloproteinase expression in rabbit temporomandibular joint condylar chondrocytes. Arthritis Rheum 2009; 60: 2714-22.
38. Yuasa T, Otani T, Koike T, Iwamoto M, Enomoto-Iwamoto M,. Wnt/β-catenin signaling stimulates matrix catabolic genes and activity in articular chondrocytes: its possible role in joint degeneration. Lab Invest 2008; 88: 264-74.
39. Enomoto-Iwamoto M, Nakamura T, Aikawa T, Higuchi Y, Yuasa T, Yamaguchi A, et al. Hedgehog proteins stimulate chondrogenic cell differentiation and cartilage formation. J Bone Miner Res 2000; 15: 1659-68.
40. Nalesso G, Sherwood J, Bertrand J, Pap T, Ramachandran M, De Bari C, et al. WNT-3A modulates articular chondrocyte phenotype by activating both canonical and noncanonical pathways. J Cell Biol 2011; 193: 551-64.
41. Chen JK, Taipale J, Cooper MK, Beachy PA,. Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened. Genes Dev 2002; 16: 2743-8.
42. Su JL, Schumacher BL, Lindley KM, Soloveychik V, Burkhart W, Triantafillou JA, et al. Detection of superficial zone protein in human and animal body fluids by cross-species monoclonal antibodies specific to superficial zone protein. Hybridoma 2001; 20: 149-57.
43. Schmidt TA, Schumacher BL, Klein TJ, Voegtline MS, Sah RL,. Synthesis of proteoglycan 4 by chondrocyte subpopulations in cartilage explants, monolayer cultures, and resurfaced cartilage cultures. Arthritis Rheum 2004; 50: 2849-57.
44. Chen X, Macica CM, Nasiri A, Broadus AE,. Regulation of articular chondrocyte proliferation and differentiation by Indian hedgehog and parathyroid hormone-related protein in mice. Arthritis Rheum 2008; 58: 3788-97.
45. Mariani FV, Martin GR,. Deciphering skeletal patterning: clues from the limb. Nature 2003; 423: 319-25.
46. Ryu JH, Chun JS,. Opposing roles of WNT-5A and WNT-11 in interleukin-1β regulation of type II collagen expression in articular chondrocytes. J Biol Chem 2006; 281: 22039-47.
47. Nugent GE, Aneloski NM, Schmidt TA, Schumacher BL, Voegtline MS, Sah RL,. Dynamic shear stimulation of bovine cartilage biosynthesis of proteoglycan 4. Arthritis Rheum 2006; 54: 1888-96.
48. Thomas RS, Clarke AR, Duance VC, Blain EJ,. Effects of Wnt3A and mechanical load on cartilage chondrocyte homeostasis. Arthritis Res Ther 2011; 13: R203.
49. Ryu JH, Kim SJ, Kim SH, Oh CD, Hwang SG, Chun CH, et al. Regulation of the chondrocyte phenotype by β-catenin. Development 2002; 129: 5541-50.
50. Dong Y, Drissi H, Chen M, Chen D, Zuscik MJ, Schwarz EM, et al. Wnt-mediated regulation of chondrocyte maturation: modulation by TGF-β. J Cell Biochem 2005; 95: 1057-68.