Inhibition of in vitro leukotriene B50 biosynthesis in human neutrophil granulocytes and docking studies of natural quinones

Natural Product Communications

Volumn 8, Issue 1, 2013, Pages 105-108

  Landaa, Premysl ^a   Kutil, Zsofia ^a,b   Temml, Veronika ^c   Malik, Jan ^b   Kokoska, Ladislav ^b   Widowitz, Ute ^d   Pribylova, Marie ^a,e   Dvorakova, Marcela ^a   Marsik, Petr ^a   Schuster, Daniela ^c   Bauer, Rudolf ^d   Vanek, Tomas ^a  

^a INSTITUTE OF EXPERIMENTAL BOTANY   (Czech Republic)

^b CZECH UNIVERSITY OF LIFE SCIENCES PRAGUE   (Czech Republic)

^c UNIVERSITY OF INNSBRUCK   (Austria)

^d UNIVERSITY OF GRAZ   (Austria)

^e CHARLES UNIVERSITY   (Czech Republic)

Author keywords

5 Lipoxygenase; Anti inflammatory activity; Dual COX LOX inhibition; Molecular docking; Natural compounds

Indexed keywords

ALKANNIN; ARACHIDONATE 5 LIPOXYGENASE; DIMETHYLCARBAMIC ACID 1 ISOPROPYL 3 METHYL 5 PYRAZOLYL ESTER; DOCEBENONE; EMODIN; JUGLONE; LEUKOTRIENE B4; PLUMBAGIN; QUINONE DERIVATIVE; SHIKONIN; THYMOHYDROQUINONE; THYMOQUINONE; UNCLASSIFIED DRUG; ZILEUTON;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MOLECULAR DOCKING; NEUTROPHIL; OXIDATION REDUCTION POTENTIAL; PROSTAGLANDIN SYNTHESIS INHIBITION;

ANTI-INFLAMMATORY AGENTS; BENZOQUINONES; CYCLOOXYGENASE 2 INHIBITORS; DRUG EVALUATION, PRECLINICAL; HUMANS; LEUKOTRIENE B4; LIPOXYGENASE INHIBITORS; MOLECULAR DOCKING SIMULATION; NEUTROPHILS; PLANT EXTRACTS; PLANTS, MEDICINAL; QUINONES; THYMOL;

EID: 84873828014     PISSN: 1934578X     EISSN: 15559475     Source Type: Journal    
DOI: None     Document Type: Article

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