Small Molecule Screening with Laser Cytometry Can Be Used to Identify Pro-Survival Molecules in Human Embryonic Stem Cells

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Sherman, Sean P ^a   Pyle, April D ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA;

ANIMAL CELL; ARTICLE; CELL FREE SYSTEM; CELL GROWTH; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; GENETIC MANIPULATION; HUMAN; HUMAN CELL; LASER SCANNING CYTOMETRY; MOUSE; NONHUMAN; PROCESS DEVELOPMENT; PROCESS OPTIMIZATION; SCREENING TEST; SIGNAL TRANSDUCTION; SINGLE CELL ANALYSIS; VALIDATION PROCESS;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ALGORITHMS; ANIMALS; CELL SURVIVAL; DNA; DRUG EVALUATION, PRECLINICAL; EMBRYONIC STEM CELLS; GREEN FLUORESCENT PROTEINS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; LASER SCANNING CYTOMETRY; MICE; OCTAMER TRANSCRIPTION FACTOR-3; PROPIDIUM; PROTEIN KINASE INHIBITORS; RHO-ASSOCIATED KINASES; SMALL MOLECULE LIBRARIES; SPECTROMETRY, FLUORESCENCE; STAINING AND LABELING; TIME FACTORS;

EID: 84873816898     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054948     Document Type: Article

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