Endothelial P2X7 receptors' expression is reduced by schistosomiasis

Purinergic Signalling

Volumn 9, Issue 1, 2013, Pages 81-89

  Oliveira, Suellen D'Arc dos Santos ^a   Coutinho Silva, Robson ^a,b   Silva, Claudia Lucia Martins ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b Ministério de Ciência Tecnologia e Inovação Salvador   (Brazil)

Author keywords

Endothelial cells; Murine; Nitric oxide; P2X7 receptors; Schistosoma mansoni

Indexed keywords

1 [N, O BIS (5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; ADENOSINE TRIPHOSPHATE; CD31 ANTIGEN; ETHIDIUM BROMIDE; NITRIC OXIDE; PURINERGIC P2X7 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; IMMUNOCYTOCHEMISTRY; MALE; MICROSCOPY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; WESTERN BLOTTING;

EID: 84873747042     PISSN: 15739538     EISSN: 15739546     Source Type: Journal    
DOI: 10.1007/s11302-012-9332-5     Document Type: Article

References (67)

1. World Health Organization (2012) Schistosomiasis. http://www. who. int/schistosomiasis/en/. Accessed 23 Feb 2012.
2. King CH, Dickman K, Tisch DJ (2005) Reassessment of the cost of chronic helmintic infection: a meta-analysis of disability-related outcomes in endemic schistosomiasis. Lancet 365: 1561-1569.
3. Schramm G, Haas H (2010) Th2 immune response against Schistosoma mansoni infection. Microbes Infect 12: 881-888.
4. File S (1995) Interaction of schistosome eggs with vascular endothelium. J Parasitol 81: 234-238.
5. Cutts L, Wilson RA (1997) The protein antigens secreted in vivo by adult male Schistosoma mansoni. Parasitology 114: 245-255.
6. Jacobs W, Bogers J, Deelder A, Wéry M, van Marck E (1997) Adult Schistosoma mansoni worms positively modulate soluble egg antigen-induced inflammatory hepatic granuloma formation in vivo. Stereological analysis and immunophenotyping of extracellular matrix proteins, adhesion molecules, and chemokines. Am J Pathol 150: 2033-2045.
7. Trottein F, Descamps L, Nutten S, Dehouck M, Angeli V, Capron A, Cecchelli R, Capron M (1999) Schistosoma mansoni activates host microvascular endothelial cells to acquire an anti-inflammatory phenotype. Infect Immun 67: 3403-3409.
8. Loeffler DA, Lundy SK, Singh KP, Gerard HC, Hudson AP, Boros DL (2002) Soluble egg antigens from Schistosoma mansoni induce angiogenesis-related processes by up-regulating vascular endothelial growth factor in human endothelial cells. J Infect Dis 185: 1650-1656.
9. Michiels C (2003) Endothelial cell function. J Cell Physiol 196: 430-443.
10. Carlos TM, Harlan JM (1994) Leukocyte-endothelial adhesion molecules. Blood 84: 2068-2101.
11. Pober JS, Sessa WC (2007) Evolving functions of endothelial cells in inflammation. Nat Rev Immunol 7: 803-815.
12. Kubes P, Sihota E, Hickey MJ (1997) Endogenous but not exogenous nitric oxide decreases TNF-alpha-induced leukocyte rolling. Am J Physiol 273: G628-G635.
13. Moncada S, Higgs EA (2006) The discovery of nitric oxide and its role in vascular biology. Br J Pharmacol 147: S193-S201.
14. De Caterina R, Libby P, Peng HB, Thannickal VJ, Rajavashisth TB, Gimbrone MA Jr, Shin WS, Liao JK (1995) Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J Clin Invest 96: 60-68.
15. Oliveira SDS, Quintas LEM, Amaral LS, Noël F, Farsky SH, Silva CLM (2011) Increased endothelial cell-leukocyte interaction in murine schistosomiasis: possible priming of endothelial cells by the disease. PLoS One 6: e23547.
16. 2+ waves at caveolae in vascular endothelial cells. J Cell Sci 124: 3477-3483.
17. Faigle M, Seessle J, Zug S, El Kasmi KC, Eltzschig HK (2008) ATP release from vascular endothelia occurs across Cx43 hemichannels and is attenuated during hypoxia. PLoS One 3: e2801.
18. Bodin P, Bailey D, Burnstock G (1991) Increased flow-induced ATP release from isolated vascular endothelial cells but not smooth muscle cells. Br J Pharmacol 103: 1203-1205.
19. Burnstock G (1999) Release of vasoactive substances from endothelial cells by shear stress and purinergic mechanosensory transduction. J Anat 194: 335-342.
20. Junger WG (2011) Immune cell regulation by autocrine purinergic signaling. Nat Rev Immunol 11: 201-212.
21. Ralevic V, Burnstock G (1998) Receptors for purines and pyrimidines. Pharmacol Rev 50: 413-492.
22. Burnstock G (2002) Purinergic signaling and vascular cell proliferation and death. Arterioscler Thromb Vasc Biol 22: 364-373.
23. Zimmermann H (2000) Extracellular metabolism of ATP and other nucleotides. Naunyn Schmiedebergs Arch Pharmacol 362: 299-309.
24. Burnstock G (2006) Purinergic signaling. Br J Pharmacol 147: S172-S181.
25. Wang L, Karlsson L, Moses S, Hultgårdh-Nilsson A, Andersson M, Borna C, Gudbjartsson T, Jern S, Erlinge D (2002) P2 receptor expression profiles in human vascular smooth muscle and endothelial cells. J Cardiovas Pharmacol 40: 841-853.
26. Guns PJ, Korda A, Crauwels HM, van Assche T, Robaye B, Boeynaems JM, Bult H (2005) Pharmacological characterization of nucleotide P2Y receptors on endothelial cells of the mouse aorta. Br J Pharmacol 146: 288-295.
27. Wilson HL, Varcoe RW, Stokes L, Holland KL, Francis SE, Dower SK, Surprenant A, Crossman DC (2007) P2X receptor characterization and IL-1/IL-1Ra release from human endothelial cells. Br J Pharmacol 151: 115-127.
28. 4 receptors mediate ATP-induced calcium influx in human vascular endothelial cell. Am J Physiol Heart Circ Physiol 279: H285-H292.
29. Harrington LS, Mitchell JA (2004) Novel role for P2X receptor activation in endothelium-dependent vasodilation. Br J Pharmacol 143: 611-617.
30. Wihlborg AK, Malmsjo M, Eyjolfsson A, Gustafsson R, Jacobson K, Erlinge D (2003) Extracellular nucleotides induce vasodilatation in human arteries via prostaglandins, nitric oxide and endothelium-derived hyperpolarising factor. Br J Pharmacol 138: 1451-1458.
31. Liu C, Mather S, Huang Y, Garland CJ, Yao X (2004) Extracellular ATP facilitates flow-induced vasodilatation in rat small mesenteric arteries. Am J Physiol Heart Circ Physiol 286: H1688-H1695.
32. 1 receptors mediate endothelial dependent vasodilation to ATP. Mol Pharmacol 72: 1132-1136.
33. da Silva CG, Specht A, Wegiel B, Ferran C, Kaczmarek E (2009) Mechanism of purinergic activation of endothelial nitric oxide synthase in endothelial cells. Circulation 119: 871-879.
34. Silva CLM, Morel N, Lenzi HL, Noël F (1998) Increased reactivity to 5-hydroxytryptamine of portal veins from mice infected with Schistosoma mansoni. Comp Biochem Physiol A Mol Integr Physiol 120: 417-423.
35. Silva CLM, Lenzi HL, Silva VFM, Paulo FO, Noël F (2003) Cellular mechanisms involved in the increased contraction of portal veins from Schistosoma mansoni-infected mice. Parasitol Res 89: 16-22.
36. Bhardwaj R, Skelly PJ (2009) Purinergic signaling and immune modulation at the schistosome surface? Trends Parasitol 25: 256-260.
37. Di Virgilio F (2007) Liaisons dangereuses: P2X7 and the inflammasome. Trends Pharmacol Sci 28: 465-472.
38. Lister MF, Sharkey J, Sawatzky DA, Hodgkiss JP, Davidson DJ, Rossi AG, Finlayson K (2007) The role of the purinergic P2X7 receptor in inflammation. J Inflamm 4: 5.
39. Lenzi HL, Romana W de S, Santos RM, Rosas A, Mota EM, Manso PP, Caputo LF, Pelajo-Machado M (2006) Four whole-istic aspects of schistosome granuloma biology: fractal arrangement, internal regulation, autopoietic component and closure. Mem Inst Oswaldo Cruz 101: 219-231.
40. Silva CLM, Tamura EK, Macedo SMD, Cecon E, Farsky SH, Alves LB, Ferreira ZF, Markus RP (2007) Melatonin inhibits microvascular endothelial cell nitric oxide production in vivo and in vitro. Br J Pharmacol 150: 1-11.
41. Marelli-Berg FM, Peek E, Lidington EA, Stauss HJ, Lechler RI (2000) Isolation of endothelial cells from murine tissue. J Immunol Methods 244: 205-215.
42. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275.
43. Coddou C, Yan Z, Obsil T, Huidobro-Toro JP, Stojilkovic SS (2011) Activation and regulation of purinergic P2X receptor channels. Pharmacol Rev 63: 641-683.
44. Schnabel R, Palmer MJ, Kilpatrick IC, Collingridge GL (1999) A CaMKII inhibitor, KN-62, facilitates DHPG-induced LTD in the CA1 region of the hippocampus. Neuropharmacology 38: 605-608.
45. Pearce EJ, MacDonald AS (2002) The immunobiology of schistosomiasis. Immunology 2: 499-511.
46. Thorgeirsson G, Robertson AL (1978) The vascular endothelium-pathobiologic significance. Am J Pathol 93: 803-848.
47. Aird WC (2007) Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms. Circ Res 100: 158-173.
48. Vanhoutte PM (2009) Endothelial dysfunction-the first step toward coronary arteriosclerosis. Circ J 73: 595-601.
49. Da'dara A, Skelly PJ (2011) Manipulation of vascular function by blood flukes? Blood Rev 25: 175-179.
50. Crosby A, Jones FM, Southwood M, Stewart S, Schermuly R, Butrous G, Dunne DW, Morrell NW (2010) Pulmonary vascular remodeling correlates with lung eggs and cytokines in murine schistosomiasis. Am J Respir Crit Care Med 181: 279-288.
51. Freedman DO, Ottesen EA (1988) Eggs of Schistosoma mansoni stimulate endothelial cell proliferation in vitro. J Infect Dis 158: 556-562.
52. Lejoly-Boisseau H, Appriou M, Seigneur M, Pruvost A, Tribouley-Duret J, Tribouley J (1999) Schistosoma mansoni: in vitro adhesion of parasite eggs to the vascular endothelium. Subsequent inhibition by a monoclonal antibody directed to a carbohydrate epitope. Exp Parasitol 91: 20-29.
53. Khakh BS, Burnstock G, Kennedy C, King BF, North RA, Seguela P, Voigt M, Humphrey PP (2001) International union of pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits. Pharmacol Rev 53: 107-118.
54. von Albertini M, Palmetshofer A, Kaczmarek E, Koziak K, Stroka D, Grey ST, Stuhlmeier KM, Robson SC (1998) Extracellular ATP and ADP activate transcription factor NF-kB and induce endothelial cell apoptosis. Biochem Biophys Res Commun 248: 822-829.
55. Adinolfi E, Pizzirani C, Idzko M, Panther E, Norgauer J, Di Virgilio F, Ferrari D (2005) P2X7 receptor: death or life? Purinergic Signal 1: 219-227.
56. Sugiyama T, Kawamura H, Yamanishi S, Kobayashi M, Katsumura K, Puro DG (2005) Regulation of P2X7-induced pore formation and cell death in pericyte-containing retinal microvessels. Am J Physiol Cell Physiol 288: C568-C576.
57. Coutinho-Silva R, Cruz CM, Persechini PM, Ojcius DM (2007) The role of P2 receptors in controlling infections by intracellular pathogens. Purinergic Signal 3: 83-90.
58. Coutinho-Silva R, Corrêa G, Sater AA, Ojcius DM (2009) The P2X7 receptor and intracellular pathogens: a continuing struggle. Purinergic Signal 5: 197-204.
59. de Jesus AR, Silva A, Santana LB, Magalhães A, de Jesus AA, de Almeida RP, Rêgo MAV, Burattini MN, Pearce EJ, Carvalho EM (2002) Clinical and immunologic evaluation of 31 patients with acute schistosomiasis mansoni. J Infect Dis 185: 98-105.
60. Zhang J, Patel JM, Li YD, Block ER (1997) Proinflammatory cytokines downregulate gene expression and activity of constitutive nitric oxide synthase in porcine pulmonary artery endothelial cells. Res Commun Mol Pathol Pharmacol 96: 71-87.
61. Bhagat K, Vallance P (1997) Inflammatory cytokines impair endothelium-dependent dilatation in human veins in vivo. Circulation 96: 3042-3047.
62. Kofler S, Nickel T, Weis M (2005) Role of cytokines in cardiovascular diseases: a focus on endothelial responses to inflammation. Clin Sci 108: 205-213.
63. Herbert DR, Orekov T, Perkins C, Finkelman FD (2008) IL-10 and TGF-beta redundantly protect against severe liver injury and mortality during acute schistosomiasis. J Immunol 181: 7214-7220.
64. Gadeock S, Tran JN, Georgiou JG, Jalilian I, Taylor RM, Wiley JS, Sluyter R (2010) TGF-β1 prevents up-regulation of the P2X7 receptor by IFN-γ and LPS in leukemic THP-1 monocytes. Biochim Biophys Acta 1798: 2058-2066.
65. Goepfert C, Imai M, Brouard S, Csizmadia E, Kaczmarek E, Robson SC (2000) CD39 modulates endothelial cell activation and apoptosis. Mol Med 6(7): 591-603.
66. Agboh KC, Webb TE, Evans RJ, Ennion SJ (2004) Functional characterization of a P2X receptor from Schistosoma mansoni. J Biol Chem 279: 41650-41657.
67. Burnstock G, Verkhratsky A (2009) Evolutionary origins of the purinergic signalling system. Acta Physiol 195: 415-447.