Mechanistic characterization of bilayer tablet formulations

Powder Technology

Volumn 236, Issue , 2013, Pages 30-36

  Akseli, Ilgaz ^a   Abebe, Admassu ^b   Sprockel, Omar ^b   Cuitiño, Alberto M ^a  

^a RUTGERS UNIVERSITY   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

Author keywords

Axial tensile strength; Bilayer interface; Bilayer tablet; Bonding; Delamination

Indexed keywords

ADJACENT LAYERS; AXIAL LOADING; AXIAL TENSILE STRENGTH; BI-LAYER; BILAYER TABLET; COMPACTION STRESS; COMPRESSION FORCE; DENSITY DISTRIBUTIONS; FRACTURE PATTERN; INTERFACIAL STRENGTH; LAYER SEPARATION; LOW POROSITY; MATERIAL RESPONSE; MECHANICAL INTEGRITY; MICRO-CRYSTALLINE CELLULOSE; PRE-COMPRESSION; PREGELATINIZED STARCHES; PRODUCTION OF; SECOND LAYER; SOLID DOSAGE FORMS; X RAY MICRO-COMPUTED TOMOGRAPHY;

BONDING; COMPACTION; COMPUTERIZED TOMOGRAPHY; DELAMINATION; SEPARATION; TENSILE STRENGTH;

FRACTURE;

MICROCRYSTALLINE CELLULOSE; STARCH;

ARTICLE; BILAYER TABLET FORMULATION; CHEMICAL BOND; DENSITY; FORCE; MECHANICAL STRESS; MICRO-COMPUTED TOMOGRAPHY; PHYSICAL CHEMISTRY; QUANTITATIVE ANALYSIS; TABLET COMPRESSION; TABLET FORMULATION; TABLET FRACTURE; TABLET POROSITY; TABLET PROPERTY; TABLET STRENGTH; TENSILE STRENGTH;

EID: 84873740922     PISSN: 00325910     EISSN: 1873328X     Source Type: Journal    
DOI: 10.1016/j.powtec.2012.05.048     Document Type: Article

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