Syntheses of lipophilic chalcones and their conformationally restricted analogues as antitubercular agents

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 5, 2013, Pages 1322-1325

  Ahmad, Imran ^a   Thakur, Jay Prakash ^a   Chanda, Debabrata ^a   Saikia, Dharmendra ^a   Khan, Feroz ^a   Dixit, Shivani ^b   Kumar, Amit ^b   Konwar, Rituraj ^b   Negi, Arvind Singh ^a   Gupta, Atul ^a  

^a CSIR CENTRAL INSTITUTE OF MEDICINAL AND AROMATIC PLANTS   (India)

^b CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Antitubercular agent; Benzopyranone; Chalcone; Coumarin; HEK 293; Mycobacterium tuberculosis

Indexed keywords

1 (2 HYDROXY 4 METHOXYPHENYL) 3 (4 HYDROXYPHENYL)PROPENONE; 2 HYDROXY 4 METHOXY ACETOPHENONE; 4 HYDROXYBENZALDEHYDE; 7 METHOXY 3 PHENYL 4 [2 (4 ACETOXY PHENYL)VINYL]BENZOPYRAN 2 ONE; 7 METHOXY 3 PHENYL 4 [2 (4 HYDROXY PHENYL)VINYL]BENZOPYRAN 2 ONE; CHALCONE DERIVATIVE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; CELL STRAIN HEK293; DRUG CONFORMATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LIPOPHILICITY; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN;

ANTITUBERCULAR AGENTS; CHALCONES; HEK293 CELLS; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR CONFORMATION; MYCOBACTERIUM TUBERCULOSIS; STRUCTURE-ACTIVITY RELATIONSHIP;

MYCOBACTERIUM TUBERCULOSIS;

EID: 84873739914     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.12.096     Document Type: Article

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