Amide derivatives of 2,3-diarylacrylophenone as estrogen receptor binding ligands

Medicinal Chemistry

Volumn 3, Issue 3, 2007, Pages 241-253

  Gupta, Atul ^a,b   Raghunandan, Resmi ^a   Kumar, Atul ^a   Maulik, Prakash R ^a   Dwivedy, Anila ^a   Keshri, Govind ^a   Mohan Singh, Man ^a   Ray, Suprabhat ^a,c  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b UNIVERSITÉ DU QUÉBEC À TROIS RIVIÈRES   (Canada)

^c NONE   (India)

Author keywords

Antiestrogens; Antifertility; Crystal structure; Docking studies; Estrogen antagonists; RBA

Indexed keywords

1 (4 METHOXYPHENYL) 2 (METHOXYPHENYL) 3 (4 HYDROXYPHENYL) 3 PROPEN 1 ONE; 1 (4 METHOXYPHENYL) 2 PHENYL 3 (4 HYDROXYPHENYL) 3 PROPEN 1 ONE; 2,3 DIARYLACRYLOPHENONE DERIVATIVE; [4 [3 (4 METHOXYPHENYL) 3 OXO 2 (4 METHOXYPHENYL)PROPENYL]PHENOXY]ACETIC ACID; [4 [3 (4 METHOXYPHENYL) 3 OXO 2 PHENYLPROPENYL]PHENOXY]ACETIC ACID; AMIDE; AMINE; ANTIESTROGEN; ESTER; ESTROGEN; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ETHINYLESTRADIOL; ETHYL 4 [4 [3 (METHOXYPHENYL) 3 OXO 2 PHENYLPROPENYL]PHENOXY)BUTYRIC ACID ESTER; ETHYL 5 [4 [3 (METHOXYPHENYL) 3 OXO 2 (4 METHOXYPHENYL)PROPENYL]PHENOXY)PENTANOIC ACID ESTER; ETHYL 5 [4 [3 (METHOXYPHENYL) 3 OXO 2 PHENYLPROPENYL]PHENOXY)PENTANOIC ACID ESTER; ETHYL 6 [4 [3 (METHOXYPHENYL) 3 OXO 2 PHENYLPROPENYL]PHENOXY)HEXANOIC ACID ESTER; ETHYL[4 [3 (4 METHOXYPHENYL) 3 OXO 2 (4 METHOXYPHENYL)PROPENYL]PHENOXY]ACETATE; ETHYL[4 [3 (4 METHOXYPHENYL) 3 OXO 2 PHENYLPROPENYL]PHENOXY]ACETIC ACID; LIGAND; N (2 ETHYLHEXYL) 2 [4 [3 (4 METHOXYPHENYL) 3 OXO 2 PHENYLPROPENYL]PHENOXY]ACETAMIDE; N BUTYL 11 (3,17BETA DIHYDROXYESTRA 1,3,5(10) TRIEN 7ALPHA YL) N METHYLUNDECANAMIDE; N BUTYL 2 [4 [3 (4 METHOXYPHENYL) 3 OXO 2 PHENYLPROPENYL]PHENOXY]ACETAMIDE; N NONYL 2 [4 [3 (4 METHOXYPHENYL) 3 OXO 2 PHENYLPROPENYL]PHENOXY]ACETAMIDE; N PROPYL 2 [4 [3 (4 METHOXYPHENYL) 3 OXO 2 PHENYLPROPENYL]PHENOXY]ACETAMIDE; PHENOL DERIVATIVE; RALOXIFENE; SEX HORMONE ANTAGONIST; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; BINDING AFFINITY; COMPUTER MODEL; DRUG ACTIVITY; DRUG BINDING SITE; DRUG HYDROLYSIS; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HORMONE INHIBITION; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

AMIDES; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; ESTROGEN ANTAGONISTS; ESTROGEN RECEPTOR MODULATORS; HYDROCARBONS, AROMATIC; LIGANDS; PHENOLS; PROTEIN BINDING; RECEPTORS, ESTROGEN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34248652417     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340607780620716     Document Type: Article

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