-
1
-
-
0023598614
-
Computer programs for the analysis of cellular survival data
-
Albright, N. (1987). Computer programs for the analysis of cellular survival data. Radiat. Res. 112, 331-340.
-
(1987)
Radiat. Res.
, vol.112
, pp. 331-340
-
-
Albright, N.1
-
2
-
-
67349286984
-
Guggulsterone induces apoptosis in colon cancer cells and inhibits tumor growth in murine colorectal cancer xenografts
-
An, M. J., Cheon, J. H., Kim, S. W., Kim, E. S., Kim, T. I., and Kim, W. H. (2009). Guggulsterone induces apoptosis in colon cancer cells and inhibits tumor growth in murine colorectal cancer xenografts. Cancer Lett. 279, 93-100.
-
(2009)
Cancer Lett.
, vol.279
, pp. 93-100
-
-
An, M.J.1
Cheon, J.H.2
Kim, S.W.3
Kim, E.S.4
Kim, T.I.5
Kim, W.H.6
-
3
-
-
39149135554
-
Screening of synthetic and plant-derived compounds for (anti)estrogenic and (anti)androgenic activities
-
Bovee, T. F., Schoonen, W. G., Hamers, A. R., Bento, M. J., and Peijnenburg, A. A. (2008). Screening of synthetic and plant-derived compounds for (anti)estrogenic and (anti)androgenic activities. Anal. Bioanal. Chem. 390, 1111-1119.
-
(2008)
Anal. Bioanal. Chem.
, vol.390
, pp. 1111-1119
-
-
Bovee, T.F.1
Schoonen, W.G.2
Hamers, A.R.3
Bento, M.J.4
Peijnenburg, A.A.5
-
4
-
-
3342977959
-
Guggulsterone activates multiple nuclear receptors and induces CYP3A gene expression through the pregnane X receptor
-
Brobst, D. E., Ding, X., Creech, K. L., Goodwin, B., Kelley, B., and Staudinger, J. L. (2004). Guggulsterone activates multiple nuclear receptors and induces CYP3A gene expression through the pregnane X receptor. J. Pharmacol. Exp. Ther. 310, 528-535.
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.310
, pp. 528-535
-
-
Brobst, D.E.1
Ding, X.2
Creech, K.L.3
Goodwin, B.4
Kelley, B.5
Staudinger, J.L.6
-
5
-
-
20144369215
-
The hypolipidemic natural product guggulsterone is a promiscuous steroid receptor ligand
-
Burris, T. P., Montrose, C., Houck, K. A., Osborne, H. E., Bocchinfuso, W. P., Yaden, B. C., Cheng, C. C., Zink, R. W., Barr, R. J., Hepler, C. D., Krishnan, V., Bullock, H. A., Burris, L. L., Galvin, R. J., Bramlett, K., and Stayrook, K. R. (2005). The hypolipidemic natural product guggulsterone is a promiscuous steroid receptor ligand. Mol. Pharmacol. 67, 948-954.
-
(2005)
Mol. Pharmacol.
, vol.67
, pp. 948-954
-
-
Burris, T.P.1
Montrose, C.2
Houck, K.A.3
Osborne, H.E.4
Bocchinfuso, W.P.5
Yaden, B.C.6
Cheng, C.C.7
Zink, R.W.8
Barr, R.J.9
Hepler, C.D.10
Krishnan, V.11
Bullock, H.A.12
Burris, L.L.13
Galvin, R.J.14
Bramlett, K.15
Stayrook, K.R.16
-
6
-
-
0029841455
-
Lipid lowering activity of guggulsterone from Commiphora mukul in hyperlipaemic rats
-
Chander, R., Khanna, A. K., and Kaapor, N. K. (1996). Lipid lowering activity of guggulsterone from Commiphora mukul in hyperlipaemic rats. Phytother. Res. 10, 508-511.
-
(1996)
Phytother. Res.
, vol.10
, pp. 508-511
-
-
Chander, R.1
Khanna, A.K.2
Kaapor, N.K.3
-
7
-
-
65549088533
-
ATR and H2AX cooperate in maintaining genome stability under replication stress
-
Chanoux, R. A., Yin, B., Urtishak, K. A., Asare, A., Bassing, C. H., and Brown, E. J. (2009). ATR and H2AX cooperate in maintaining genome stability under replication stress. J. Biol. Chem. 284, 5994-6003.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 5994-6003
-
-
Chanoux, R.A.1
Yin, B.2
Urtishak, K.A.3
Asare, A.4
Bassing, C.H.5
Brown, E.J.6
-
8
-
-
77954710908
-
Akt signaling pathway: a target for radiosensitizing human malignant glioma
-
Chautard, E., Loubeau, G., Tchirkov, A., Chassagne, J., Vermot-Desroches, C., Morel, L., and Verrelle, P. (2010). Akt signaling pathway: a target for radiosensitizing human malignant glioma. Neuro Oncol. 12, 434-443.
-
(2010)
Neuro Oncol.
, vol.12
, pp. 434-443
-
-
Chautard, E.1
Loubeau, G.2
Tchirkov, A.3
Chassagne, J.4
Vermot-Desroches, C.5
Morel, L.6
Verrelle, P.7
-
9
-
-
18044391836
-
Modulation of response to radiation of human lung cancer cells following insulin-like growth factor 1 receptor inactivation
-
Cosaceanu, D., Carapancea, M., Castro, J., Ekedahl, J., Kanter, L., Lewensohn, R., and Dricu, A. (2005). Modulation of response to radiation of human lung cancer cells following insulin-like growth factor 1 receptor inactivation. Cancer Lett. 222, 173-181.
-
(2005)
Cancer Lett.
, vol.222
, pp. 173-181
-
-
Cosaceanu, D.1
Carapancea, M.2
Castro, J.3
Ekedahl, J.4
Kanter, L.5
Lewensohn, R.6
Dricu, A.7
-
10
-
-
78049441629
-
Targeting inflammatory pathways for tumor radiosensitization
-
Deorukhkar, A., and Krishnan, S. (2010). Targeting inflammatory pathways for tumor radiosensitization. Biochem. Pharmacol. 80, 1904-1914.
-
(2010)
Biochem. Pharmacol.
, vol.80
, pp. 1904-1914
-
-
Deorukhkar, A.1
Krishnan, S.2
-
11
-
-
0019155827
-
Hypolipidemic activity of guggal resin (Commiphora mukul) and garlic (Allium sativum Linn.) in dogs (Canis familiaris) and monkeys (Presbytis entellus entellus Dufresne)
-
Dixit, V. P., Joshi, S., Sinha, R., Bharvava, S. K., and Varma, M. (1980). Hypolipidemic activity of guggal resin (Commiphora mukul) and garlic (Allium sativum Linn.) in dogs (Canis familiaris) and monkeys (Presbytis entellus entellus Dufresne). Biochem. Exp. Biol. 16, 421-424.
-
(1980)
Biochem. Exp. Biol.
, vol.16
, pp. 421-424
-
-
Dixit, V.P.1
Joshi, S.2
Sinha, R.3
Bharvava, S.K.4
Varma, M.5
-
12
-
-
60749091249
-
Targeted cancer therapeutics
-
discussion 1267
-
Hait, W. N., and Hambley, T. W. (2009). Targeted cancer therapeutics. Cancer Res. 69, 1263-1267; discussion 1267.
-
(2009)
Cancer Res.
, vol.69
, pp. 1263-1267
-
-
Hait, W.N.1
Hambley, T.W.2
-
14
-
-
60549102499
-
Is anticancer drug development heading in the right direction?
-
Hambley, T. W., and Hait, W. N. (2009). Is anticancer drug development heading in the right direction? Cancer Res. 69, 1259-1262.
-
(2009)
Cancer Res.
, vol.69
, pp. 1259-1262
-
-
Hambley, T.W.1
Hait, W.N.2
-
15
-
-
68149137376
-
Understanding resistance to tamoxifen in hormone receptor-positive breast cancer
-
Higgins, M. J., and Stearns, V. (2009). Understanding resistance to tamoxifen in hormone receptor-positive breast cancer. Clin. Chem. 55, 1453-1455.
-
(2009)
Clin. Chem.
, vol.55
, pp. 1453-1455
-
-
Higgins, M.J.1
Stearns, V.2
-
16
-
-
0032573165
-
Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms
-
Li, N., and Karin, M. (1998). Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms. Proc. Natl. Acad. Sci. U.S.A. 95, 13012-13017.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 13012-13017
-
-
Li, N.1
Karin, M.2
-
17
-
-
0028196623
-
In vitro studies of Taxol as a radiation sensitizer in human tumor cells
-
Liebmann, J., Cook, J. A., Fisher, J., Teague, D., and Mitchell, J. B. (1994). In vitro studies of Taxol as a radiation sensitizer in human tumor cells. J. Natl. Cancer Inst. 86, 441-446.
-
(1994)
J. Natl. Cancer Inst.
, vol.86
, pp. 441-446
-
-
Liebmann, J.1
Cook, J.A.2
Fisher, J.3
Teague, D.4
Mitchell, J.B.5
-
18
-
-
45049087913
-
Guggulsterone, a plant sterol, inhibits NF-kappaB activation and protects pancreatic beta cells from cytokine toxicity
-
Lv, N., Song, M. Y., Kim, E. K., Park, J. W., Kwon, K. B., and Park, B. H. (2008). Guggulsterone, a plant sterol, inhibits NF-kappaB activation and protects pancreatic beta cells from cytokine toxicity. Mol. Cell. Endocrinol. 289, 49-59.
-
(2008)
Mol. Cell. Endocrinol.
, vol.289
, pp. 49-59
-
-
Lv, N.1
Song, M.Y.2
Kim, E.K.3
Park, J.W.4
Kwon, K.B.5
Park, B.H.6
-
19
-
-
64249135764
-
Novel agents on the horizon for cancer therapy
-
Ma, W. W., and Adjei, A. A. (2009). Novel agents on the horizon for cancer therapy. CA Cancer J. Clin. 59, 111-137.
-
(2009)
CA Cancer J. Clin.
, vol.59
, pp. 111-137
-
-
Ma, W.W.1
Adjei, A.A.2
-
20
-
-
0035811559
-
Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase
-
Macaulay, V. M., Salisbury, A. J., Bohula, E. A., Playford, M. P., Smorodinsky, N. I., and Shiloh, Y. (2001). Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase. Oncogene 20, 4029-4040.
-
(2001)
Oncogene
, vol.20
, pp. 4029-4040
-
-
Macaulay, V.M.1
Salisbury, A.J.2
Bohula, E.A.3
Playford, M.P.4
Smorodinsky, N.I.5
Shiloh, Y.6
-
21
-
-
64649105115
-
DNA topoisomerase II and its growing repertoire of biological functions
-
Nitiss, J. L. (2009). DNA topoisomerase II and its growing repertoire of biological functions. Nat. Rev. Cancer 9, 327-337.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 327-337
-
-
Nitiss, J.L.1
-
22
-
-
0024658637
-
Clinical trials with gugulipid. A new hypolipidaemic agent
-
Nityanand, S., Srivastava, J. S., and Asthana, O. P. (1989). Clinical trials with gugulipid. A new hypolipidaemic agent. J. Assoc. Physicians India 37, 323-328.
-
(1989)
J. Assoc. Physicians India
, vol.37
, pp. 323-328
-
-
Nityanand, S.1
Srivastava, J.S.2
Asthana, O.P.3
-
23
-
-
58049202275
-
Resin from the mukul myrrh tree, guggul, can it be used for treating hypercholesterolemia? A randomized, controlled study
-
Nohr, L. A., Rasmussen, L. B., and Straand, J. (2009). Resin from the mukul myrrh tree, guggul, can it be used for treating hypercholesterolemia? A randomized, controlled study. Complement. Ther. Med. 17, 16-22.
-
(2009)
Complement. Ther. Med.
, vol.17
, pp. 16-22
-
-
Nohr, L.A.1
Rasmussen, L.B.2
Straand, J.3
-
24
-
-
0030497834
-
Changes in radiation sensitivity and steroid receptor content induced by hormonal agents and ionizing radiation in breast cancer cells in vitro
-
Paulsen, G. H., Strickert, T., Marthinsen, A. B., and Lundgren, S. (1996). Changes in radiation sensitivity and steroid receptor content induced by hormonal agents and ionizing radiation in breast cancer cells in vitro. Acta Oncol. 35, 1011-1019.
-
(1996)
Acta Oncol.
, vol.35
, pp. 1011-1019
-
-
Paulsen, G.H.1
Strickert, T.2
Marthinsen, A.B.3
Lundgren, S.4
-
25
-
-
0035852706
-
ATM-dependent expression of the insulin-like growth factor-I receptor in a pathway regulating radiation response
-
Peretz, S., Jensen, R., Baserga, R., and Glazer, P. M. (2001). ATM-dependent expression of the insulin-like growth factor-I receptor in a pathway regulating radiation response. Proc. Natl. Acad. Sci. U.S.A. 98, 1676-1681.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 1676-1681
-
-
Peretz, S.1
Jensen, R.2
Baserga, R.3
Glazer, P.M.4
-
26
-
-
0031051830
-
Insulin-like growth factor binding protein-3 and insulin receptor substrate-1 in breast cancer: correlation with clinical parameters and disease-free survival
-
Rocha, R. L., Hilsenbeck, S. G., Jackson, J. G., Vandenberg, C. L., Weng, C., Lee, A. V., and Yee, D. (1997). Insulin-like growth factor binding protein-3 and insulin receptor substrate-1 in breast cancer: correlation with clinical parameters and disease-free survival. Clin. Cancer Res. 3, 103-109.
-
(1997)
Clin. Cancer Res.
, vol.3
, pp. 103-109
-
-
Rocha, R.L.1
Hilsenbeck, S.G.2
Jackson, J.G.3
Vandenberg, C.L.4
Weng, C.5
Lee, A.V.6
Yee, D.7
-
27
-
-
30344476414
-
Guggulsterones induce apoptosis and differentiation in acute myeloid leukemia: identification of isomer-specific antileukemic activities of the pregnadienedione structure
-
Samudio, I., Konopleva, M., Safe, S., Mcqueen, T., and Andreeff, M. (2005). Guggulsterones induce apoptosis and differentiation in acute myeloid leukemia: identification of isomer-specific antileukemic activities of the pregnadienedione structure. Mol. Cancer Ther. 4, 1982-1992.
-
(2005)
Mol. Cancer Ther.
, vol.4
, pp. 1982-1992
-
-
Samudio, I.1
Konopleva, M.2
Safe, S.3
Mcqueen, T.4
Andreeff, M.5
-
28
-
-
8744234076
-
Guggulsterone inhibits NF-kappaB and IkappaBalpha kinase activation, suppresses expression of anti-apoptotic gene products, and enhances apoptosis
-
Shishodia, S., and Aggarwal, B. B. (2004). Guggulsterone inhibits NF-kappaB and IkappaBalpha kinase activation, suppresses expression of anti-apoptotic gene products, and enhances apoptosis. J. Biol. Chem. 279, 47148-47158.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 47148-47158
-
-
Shishodia, S.1
Aggarwal, B.B.2
-
29
-
-
58149153271
-
The guggul for chronic diseases: ancient medicine, modern targets
-
Shishodia, S., Harikumar, K. B., Dass, S., Ramawat, K. G., and Aggarwal, B. B. (2008). The guggul for chronic diseases: ancient medicine, modern targets. Anticancer Res. 28, 3647-3664.
-
(2008)
Anticancer Res.
, vol.28
, pp. 3647-3664
-
-
Shishodia, S.1
Harikumar, K.B.2
Dass, S.3
Ramawat, K.G.4
Aggarwal, B.B.5
-
30
-
-
34249058341
-
Guggulsterone inhibits tumor cell proliferation, induces S-phase arrest, and promotes apoptosis through activation of c-Jun N-terminal kinase, suppression of Akt pathway, and downregulation of antiapoptotic gene products
-
Shishodia, S., Sethi, G., Ahn, K. S., and Aggarwal, B. B. (2007). Guggulsterone inhibits tumor cell proliferation, induces S-phase arrest, and promotes apoptosis through activation of c-Jun N-terminal kinase, suppression of Akt pathway, and downregulation of antiapoptotic gene products. Biochem. Pharmacol. 74, 118-130.
-
(2007)
Biochem. Pharmacol.
, vol.74
, pp. 118-130
-
-
Shishodia, S.1
Sethi, G.2
Ahn, K.S.3
Aggarwal, B.B.4
-
31
-
-
34547614631
-
Guggulsterone-induced apoptosis in human prostate cancer cells is caused by reactive oxygen intermediate dependent activation of c-Jun NH2-terminal kinase
-
Singh, S. V., Choi, S., Zeng, Y., Hahm, E. R., and Xiao, D. (2007). Guggulsterone-induced apoptosis in human prostate cancer cells is caused by reactive oxygen intermediate dependent activation of c-Jun NH2-terminal kinase. Cancer Res. 67, 7439-7449.
-
(2007)
Cancer Res.
, vol.67
, pp. 7439-7449
-
-
Singh, S.V.1
Choi, S.2
Zeng, Y.3
Hahm, E.R.4
Xiao, D.5
-
32
-
-
28044460494
-
Caspase-dependent apoptosis induction by guggulsterone, a constituent of ayurvedic medicinal plant Commiphora mukul, in PC-3 human prostate cancer cells is mediated by Bax and Bak
-
Singh, S. V., Zeng, Y., Xiao, D., Vogel, V. G., Nelson, J. B., Dhir, R., and Tripathi, Y. B. (2005). Caspase-dependent apoptosis induction by guggulsterone, a constituent of ayurvedic medicinal plant Commiphora mukul, in PC-3 human prostate cancer cells is mediated by Bax and Bak. Mol. Cancer Ther. 4, 1747-1754.
-
(2005)
Mol. Cancer Ther.
, vol.4
, pp. 1747-1754
-
-
Singh, S.V.1
Zeng, Y.2
Xiao, D.3
Vogel, V.G.4
Nelson, J.B.5
Dhir, R.6
Tripathi, Y.B.7
-
33
-
-
0042160272
-
Guggulipid for the treatment of hypercholesterolemia: a randomized controlled trial
-
Szapary, P. O., Wolfe, M. L., Bloedon, L. T., Cucchiara, A. J., Dermarderosian, A. H., Cirigliano, M. D., and Rader, D. J. (2003). Guggulipid for the treatment of hypercholesterolemia: a randomized controlled trial. JAMA 290, 765-772.
-
(2003)
JAMA
, vol.290
, pp. 765-772
-
-
Szapary, P.O.1
Wolfe, M.L.2
Bloedon, L.T.3
Cucchiara, A.J.4
Dermarderosian, A.H.5
Cirigliano, M.D.6
Rader, D.J.7
-
34
-
-
0037205046
-
A natural product that lowers cholesterol as an antagonist ligand for FXR
-
Urizar, N. L., Liverman, A. B., Dodds, D. T., Silva, F. V., Ordentlich, P., Yan, Y., Gonzalez, F. J., Heyman, R. A., Mangelsdorf, D. J., and Moore, D. D. (2002). A natural product that lowers cholesterol as an antagonist ligand for FXR. Science 296, 1703-1706.
-
(2002)
Science
, vol.296
, pp. 1703-1706
-
-
Urizar, N.L.1
Liverman, A.B.2
Dodds, D.T.3
Silva, F.V.4
Ordentlich, P.5
Yan, Y.6
Gonzalez, F.J.7
Heyman, R.A.8
Mangelsdorf, D.J.9
Moore, D.D.10
-
35
-
-
0029858387
-
TNF-and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB
-
Wang, C. Y., Mayo, M. W., and Baldwin, A. S. Jr. (1996). TNF-and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB. Science 274, 784-787.
-
(1996)
Science
, vol.274
, pp. 784-787
-
-
Wang, C.Y.1
Mayo, M.W.2
Baldwin Jr., A.S.3
-
36
-
-
0024806395
-
Modulation in the radiosensitivity of MCF-7 human breast carcinoma cells by 17B-estradiol and tamoxifen
-
Wazer, D. E., Tercilla, O. F., Lin, P. S., and Schmidt-Ullrich, R. (1989). Modulation in the radiosensitivity of MCF-7 human breast carcinoma cells by 17B-estradiol and tamoxifen. Br. J. Radiol. 62, 1079-1083.
-
(1989)
Br. J. Radiol.
, vol.62
, pp. 1079-1083
-
-
Wazer, D.E.1
Tercilla, O.F.2
Lin, P.S.3
Schmidt-Ullrich, R.4
-
37
-
-
38349143690
-
z-Guggulsterone, a constituent of ayurvedic medicinal plant Commiphora mukul, inhibits angiogenesis in vitro and in vivo
-
Xiao, D., and Singh, S. V. (2008). z-Guggulsterone, a constituent of ayurvedic medicinal plant Commiphora mukul, inhibits angiogenesis in vitro and in vivo. Mol. Cancer Ther. 7, 171-180.
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 171-180
-
-
Xiao, D.1
Singh, S.V.2
-
38
-
-
42649130051
-
Enhanced inhibition of adipogenesis and induction of apoptosis in 3T3-L1 adipocytes with combinations of resveratrol and quercetin
-
Yang, J. Y., Della-Fera, M. A., Rayalam, S., Ambati, S., Hartzell, D. L., Park, H. J., and Baile, C. A. (2008). Enhanced inhibition of adipogenesis and induction of apoptosis in 3T3-L1 adipocytes with combinations of resveratrol and quercetin. Life Sci. 82, 1032-1039.
-
(2008)
Life Sci.
, vol.82
, pp. 1032-1039
-
-
Yang, J.Y.1
Della-Fera, M.A.2
Rayalam, S.3
Ambati, S.4
Hartzell, D.L.5
Park, H.J.6
Baile, C.A.7
|