Intratumoral delivery of paclitaxel using a thermosensitive hydrogel in human tumor xenografts

Archives of Pharmacal Research

Volumn 36, Issue 1, 2013, Pages 94-101

  Kim, Jung Ho ^a   Lee, Joo Ho ^d   Kim, Kwang Suck ^a   Na, Kun ^a   Song, Soo Chang ^b   Lee, Jaehwi ^c   Kuh, Hyo Jeong ^a  

^a The Catholic University of Korea   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

^c Chung Ang University   (South Korea)

^d SunMoon University   (South Korea)

Author keywords

Drug delivery system; Hydrogel; Paclitaxel; Pharmacokinetics; Poly(organophosphazene); Solid tumors

Indexed keywords

DRUG CARRIER; PACLITAXEL; POLY(ORGANOPHOSPHAZENE); POLYMER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BODY TEMPERATURE; CANCER CELL; CANCER INHIBITION; CANCER TISSUE; COLORECTAL CANCER; DRUG ACCUMULATION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG HALF LIFE; DRUG PENETRATION; DRUG RELEASE; DRUG TUMOR LEVEL; FEMALE; HEAT SENSITIVITY; HUMAN; HUMAN CELL; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; MAXIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN; STOMACH CANCER; TIME TO MAXIMUM PLASMA CONCENTRATION; TUMOR GROWTH; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BODY TEMPERATURE; CELL LINE, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG CARRIERS; FEMALE; HUMANS; HYDROGELS; INJECTIONS; MICE; MICE, INBRED BALB C; MICE, NUDE; ORGANOPHOSPHORUS COMPOUNDS; PACLITAXEL; POLYMERS; RHEOLOGY; VISCOSITY; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84873724882     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-013-0013-x     Document Type: Article

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