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Volumn 65, Issue 1, 2013, Pages 110-117

Icariside II induces apoptosis of melanoma cells through the downregulation of survival pathways

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; FLAVONOID GLYCOSIDE; ICARISIDE II; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STAT3 PROTEIN; SURVIVIN; UNCLASSIFIED DRUG;

EID: 84873716005     PISSN: 01635581     EISSN: 15327914     Source Type: Journal    
DOI: 10.1080/01635581.2013.741745     Document Type: Article
Times cited : (26)

References (38)
  • 1
    • 77956931735 scopus 로고    scopus 로고
    • The evolution of melanoma diagnosis: 25 years beyond the ABCDs
    • Rigel DS, Russak J, Friedman R: The evolution of melanoma diagnosis: 25 years beyond the ABCDs. CA Cancer J Clin 60, 301-316, 2010.
    • (2010) CA Cancer J Clin , vol.60 , pp. 301-316
    • Rigel, D.S.1    Russak, J.2    Friedman, R.3
  • 5
    • 78649365504 scopus 로고    scopus 로고
    • Advances in systemic treatment of melanoma
    • Eggermont AM: Advances in systemic treatment of melanoma. Ann Oncol 21(Suppl 7), 339-344, 2010.
    • (2010) Ann Oncol , vol.21 , Issue.SUPPL. 7 , pp. 339-344
    • Eggermont, A.M.1
  • 7
    • 1042302005 scopus 로고    scopus 로고
    • The STATs of cancer-new molecular targets come of age
    • Yu H and Jove R: The STATs of cancer-new molecular targets come of age. Nat Rev Cancer 4, 97-105, 2004.
    • (2004) Nat Rev Cancer , vol.4 , pp. 97-105
    • Yu, H.1    Jove, R.2
  • 8
    • 33947417336 scopus 로고    scopus 로고
    • Regulation of metastases by signal transducer and activator of transcription 3 signaling pathway: Clinical implications
    • Huang S: Regulation of metastases by signal transducer and activator of transcription 3 signaling pathway: clinical implications. Clin Cancer Res 13, 1362-1366, 2007.
    • (2007) Clin Cancer Res , vol.13 , pp. 1362-1366
    • Huang, S.1
  • 9
    • 0036554816 scopus 로고    scopus 로고
    • Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
    • Buettner R, Mora LB, and Jove R: Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin Cancer Res 8, 945-954, 2002.
    • (2002) Clin Cancer Res , vol.8 , pp. 945-954
    • Buettner, R.1    Mora, L.B.2    Jove, R.3
  • 10
    • 20944441928 scopus 로고    scopus 로고
    • Validating Stat3 in cancer therapy
    • Darnell JE: Validating Stat3 in cancer therapy. Nat Med 11, 595-596, 2005.
    • (2005) Nat Med , vol.11 , pp. 595-596
    • Darnell, J.E.1
  • 11
    • 28644445445 scopus 로고    scopus 로고
    • Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity
    • Kortylewski M, Kujawski M, Wang T, Wei S, Zhang S, et al.: Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity. Nat Med 11, 1314-1321, 2005.
    • (2005) Nat Med , vol.11 , pp. 1314-1321
    • Kortylewski, M.1    Kujawski, M.2    Wang, T.3    Wei, S.4    Zhang, S.5
  • 12
    • 0032718891 scopus 로고    scopus 로고
    • Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo
    • Niu G, Heller R, Catlett-Falcone R, Coppola D, Jaroszeski M, et al.: Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo. Cancer Res 59, 5059-5063, 1999.
    • (1999) Cancer Res , vol.59 , pp. 5059-5063
    • Niu, G.1    Heller, R.2    Catlett-Falcone, R.3    Coppola, D.4    Jaroszeski, M.5
  • 13
    • 0032984589 scopus 로고    scopus 로고
    • Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells
    • Catlett-Falcone R, Landowski TH, Oshiro MM, Turkson J, Levitzki A, et al.: Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunity 10, 105-115, 1999.
    • (1999) Immunity , vol.10 , pp. 105-115
    • Catlett-Falcone, R.1    Landowski, T.H.2    Oshiro, M.M.3    Turkson, J.4    Levitzki, A.5
  • 14
    • 0346995278 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathway-dependent tumor-specific survival signaling in melanoma cells through inactivation of the proapoptotic protein bad
    • Eisenmann KM, Van Brocklin MW, Staffend NA, Kitchen SM, and Koo HM: Mitogen-activated protein kinase pathway-dependent tumor-specific survival signaling in melanoma cells through inactivation of the proapoptotic protein bad. Cancer Res 63, 8330-8337, 2003.
    • (2003) Cancer Res , vol.63 , pp. 8330-8337
    • Eisenmann, K.M.1    Van Brocklin, M.W.2    Staffend, N.A.3    Kitchen, S.M.4    Koo, H.M.5
  • 15
    • 0037022666 scopus 로고    scopus 로고
    • Apoptosis andmelanogenesis in human melanoma cells induced by anthrax lethal factor inactivation of mitogen-activated protein kinase kinase
    • Koo HM, Van Brocklin M, McWilliams MJ, Leppla SH, Duesbery NS, et al.: Apoptosis andmelanogenesis in human melanoma cells induced by anthrax lethal factor inactivation of mitogen-activated protein kinase kinase. Proc Natl Acad Sci U S A 99, 3052-3057, 2002.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 3052-3057
    • Koo, H.M.1    Van Brocklin, M.2    McWilliams, M.J.3    Leppla, S.H.4    Duesbery, N.S.5
  • 16
    • 34548096400 scopus 로고    scopus 로고
    • Apoptosis induction in human melanoma cells by inhibition of MEK is caspaseindependent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1
    • Wang YF, Jiang CC, Kiejda KA, Gillespie S, Zhang XD, et al.: Apoptosis induction in human melanoma cells by inhibition of MEK is caspaseindependent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1. Clin Cancer Res 13, 4934-4942, 2007.
    • (2007) Clin Cancer Res , vol.13 , pp. 4934-4942
    • Wang, Y.F.1    Jiang, C.C.2    Kiejda, K.A.3    Gillespie, S.4    Zhang, X.D.5
  • 17
    • 0035075267 scopus 로고    scopus 로고
    • Effects of the aqueous extract of epimedii herba on the antibody responses in mice
    • Kim JH, Mun YJ, Im SJ, Han JH, Lee HS, et al.: Effects of the aqueous extract of epimedii herba on the antibody responses in mice. Int Immunopharmacol 1, 935-944, 2001.
    • (2001) Int Immunopharmacol , vol.1 , pp. 935-944
    • Kim, J.H.1    Mun, Y.J.2    Im, S.J.3    Han, J.H.4    Lee, H.S.5
  • 18
    • 30344461021 scopus 로고    scopus 로고
    • Optimization for quantitative determination of four flavonoids in Epimedium by capillary zone electrophoresis coupled with diode array detection using central composite design
    • Liu JJ, Li SP, and Wang YT: Optimization for quantitative determination of four flavonoids in Epimedium by capillary zone electrophoresis coupled with diode array detection using central composite design. J Chromatogr A 1103, 344-349, 2006.
    • (2006) J Chromatogr A , vol.1103 , pp. 344-349
    • Liu, J.J.1    Li, S.P.2    Wang, Y.T.3
  • 19
    • 0029111787 scopus 로고
    • Immunoregulatory effects of the herba Epimediia glycoside icariin
    • He W, Sun H, Yang B, Zhang D, and Kabelitz D: Immunoregulatory effects of the herba Epimediia glycoside icariin. Arzneimittelforschung 45, 910-913, 1995.
    • (1995) Arzneimittelforschung , vol.45 , pp. 910-913
    • He, W.1    Sun, H.2    Yang, B.3    Zhang, D.4    Kabelitz, D.5
  • 20
    • 34250670731 scopus 로고    scopus 로고
    • Anovel anticancer agent, icaritin, induced cell growth inhibition, G1 arrest and mitochondrial transmembrane potential drop in human prostate carcinoma PC-3 cells
    • Huang X, Zhu D, and Lou Y: Anovel anticancer agent, icaritin, induced cell growth inhibition, G1 arrest and mitochondrial transmembrane potential drop in human prostate carcinoma PC-3 cells. Eur J Pharmacol 564, 26-36, 2007.
    • (2007) Eur J Pharmacol , vol.564 , pp. 26-36
    • Huang, X.1    Zhu, D.2    Lou, Y.3
  • 21
    • 67349233455 scopus 로고    scopus 로고
    • Cyclooxygenase- 2/prostaglandin E2 pathway mediates icariside II induced apoptosis in human PC-3 prostate cancer cells
    • Lee KS, Lee HJ, Ahn KS, Kim SH, Nam D, et al.: Cyclooxygenase- 2/prostaglandin E2 pathway mediates icariside II induced apoptosis in human PC-3 prostate cancer cells. Cancer Lett 280, 93-100, 2009.
    • (2009) Cancer Lett , vol.280 , pp. 93-100
    • Lee, K.S.1    Lee, H.J.2    Ahn, K.S.3    Kim, S.H.4    Nam, D.5
  • 22
    • 37549017760 scopus 로고    scopus 로고
    • Icariside II from Epimedium koreanum inhibits hypoxia-inducible factor-1alpha in human osteosarcoma cells
    • Choi HJ, Eun JS, Kim DK, Li RH, Shin TY, et al.: Icariside II from Epimedium koreanum inhibits hypoxia-inducible factor-1alpha in human osteosarcoma cells. Eur J Pharmacol 579, 58-65, 2008.
    • (2008) Eur J Pharmacol , vol.579 , pp. 58-65
    • Choi, H.J.1    Eun, J.S.2    Kim, D.K.3    Li, R.H.4    Shin, T.Y.5
  • 23
    • 43749089808 scopus 로고    scopus 로고
    • Statistically designed enzymatic hydrolysis for optimized production of icariside II as a novel melanogenesis inhibitor
    • Park JS, Park HY, Rho HS, Ahn S, Kim DH, et al.: Statistically designed enzymatic hydrolysis for optimized production of icariside II as a novel melanogenesis inhibitor. J Microbiol Biotechnol 18, 110-117, 2008.
    • (2008) J Microbiol Biotechnol , vol.18 , pp. 110-117
    • Park, J.S.1    Park, H.Y.2    Rho, H.S.3    Ahn, S.4    Kim, D.H.5
  • 24
    • 77954217199 scopus 로고    scopus 로고
    • Preparation of icariside II from icariin by enzymatic hydrolysis method
    • Xia Q, Xu D, Huang Z, Liu J, Wang X, et al.: Preparation of icariside II from icariin by enzymatic hydrolysis method. Fitoterapia 81, 437-442, 2010.
    • (2010) Fitoterapia , vol.81 , pp. 437-442
    • Xia, Q.1    Xu, D.2    Huang, Z.3    Liu, J.4    Wang, X.5
  • 25
    • 13844292729 scopus 로고    scopus 로고
    • Dynamic monitoring of cytotoxicity on microelectronic sensors
    • Xing JZ, Zhu L, Jackson JA, Gabos S, Sun XJ, et al.: Dynamic monitoring of cytotoxicity on microelectronic sensors. Chem Res Toxicol 18, 154-161, 2005.
    • (2005) Chem Res Toxicol , vol.18 , pp. 154-161
    • Xing, J.Z.1    Zhu, L.2    Jackson, J.A.3    Gabos, S.4    Sun, X.J.5
  • 26
    • 77952729474 scopus 로고    scopus 로고
    • Formulation and delivery of splice-correction antisense oligonucleotides by amino acid modified polyethylenimine
    • Zaghloul EM, Viola JR, Zuber G, Smith CI, and Lundin KE: Formulation and delivery of splice-correction antisense oligonucleotides by amino acid modified polyethylenimine. Mol Pharm 7, 652-663, 2010.
    • (2010) Mol Pharm , vol.7 , pp. 652-663
    • Zaghloul, E.M.1    Viola, J.R.2    Zuber, G.3    Smith, C.I.4    Lundin, K.E.5
  • 27
    • 0034278085 scopus 로고    scopus 로고
    • The IAP family: Endogenous caspase inhibitors with multiple biological activities
    • Yang YL and Li XM: The IAP family: endogenous caspase inhibitors with multiple biological activities. Cell Res 10, 169-177, 2000.
    • (2000) Cell Res , vol.10 , pp. 169-177
    • Yang, Y.L.1    Li, X.M.2
  • 28
    • 5644259587 scopus 로고    scopus 로고
    • Inhibitor of apoptosis proteins: Translating basic knowledge into clinical practice
    • Schimmer AD: Inhibitor of apoptosis proteins: translating basic knowledge into clinical practice. Cancer Res 64, 7183-7190, 2004.
    • (2004) Cancer Res , vol.64 , pp. 7183-7190
    • Schimmer, A.D.1
  • 30
    • 0038001179 scopus 로고    scopus 로고
    • ERK and PI3K negatively regulate STAT-transcriptional activities in human melanoma cells: Implications towards sensitization to apoptosis
    • Krasilnikov M, Ivanov VN, Dong J, and Ronai Z: ERK and PI3K negatively regulate STAT-transcriptional activities in human melanoma cells: implications towards sensitization to apoptosis. Oncogene 22, 4092-4101, 2003.
    • (2003) Oncogene , vol.22 , pp. 4092-4101
    • Krasilnikov, M.1    Ivanov, V.N.2    Dong, J.3    Ronai, Z.4
  • 31
    • 78649622426 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 3 activation up-regulates interleukin-6 autocrine production: A biochemical and genetic study of established cancer cell lines and clinical isolated human cancer cells
    • Huang WL, Yeh HH, Lin CC, Lai WW, Chang JY, et al.: Signal transducer and activator of transcription 3 activation up-regulates interleukin-6 autocrine production: a biochemical and genetic study of established cancer cell lines and clinical isolated human cancer cells. Mol Cancer 9, 309, 2010.
    • (2010) Mol Cancer , vol.9 , pp. 309
    • Huang, W.L.1    Yeh, H.H.2    Lin, C.C.3    Lai, W.W.4    Chang, J.Y.5
  • 32
    • 0037115394 scopus 로고    scopus 로고
    • Constitutive activation of Akt/protein kinase B in melanoma leads to up-regulation of nuclear factor-kappa B and tumor progression
    • Dhawan P, Singh AB, Ellis DL, and Richmond A: Constitutive activation of Akt/protein kinase B in melanoma leads to up-regulation of nuclear factor-kappa B and tumor progression. Cancer Res 62, 7335-7342, 2002.
    • (2002) Cancer Res , vol.62 , pp. 7335-7342
    • Dhawan, P.1    Singh, A.B.2    Ellis, D.L.3    Richmond, A.4
  • 33
    • 0037228959 scopus 로고    scopus 로고
    • Suppression of survivin phosphorylation on Thr34 by flavopiridol enhances tumor cell apoptosis
    • Wall NR, O'Connor DS, Plescia J, Pommier Y, Altieri DC: Suppression of survivin phosphorylation on Thr34 by flavopiridol enhances tumor cell apoptosis. Cancer Res 63, 230-235, 2003.
    • (2003) Cancer Res , vol.63 , pp. 230-235
    • Wall, N.R.1    O'Connor, D.S.2    Plescia, J.3    Pommier, Y.4    Altieri, D.C.5
  • 34
    • 0036551756 scopus 로고    scopus 로고
    • Survivin expression and resistance to anticancer treatments: Perspectives for new therapeutic interventions
    • Zaffaroni N and Daidone MG: Survivin expression and resistance to anticancer treatments: perspectives for new therapeutic interventions. Drug Resist Updat 5, 65-72, 2002.
    • (2002) Drug Resist Updat , vol.5 , pp. 65-72
    • Zaffaroni, N.1    Daidone, M.G.2
  • 35
    • 0036896253 scopus 로고    scopus 로고
    • Mitogen-actived protein kinase activation is an early event in melanoma progression
    • Cohen C, Zavala-Pompa A, Sequeira JH, Shoji M, Sexton DG, et al.: Mitogen-actived protein kinase activation is an early event in melanoma progression. Clin Cancer Res 8, 3728-3733, 2002.
    • (2002) Clin Cancer Res , vol.8 , pp. 3728-3733
    • Cohen, C.1    Zavala-Pompa, A.2    Sequeira, J.H.3    Shoji, M.4    Sexton, D.G.5
  • 36
    • 0037040901 scopus 로고    scopus 로고
    • A novel NF-kappa B-inducing kinase-MAPK signaling pathway up-regulates NF-kappa B activity in melanoma cells
    • Dhawan P and Richmond A: A novel NF-kappa B-inducing kinase-MAPK signaling pathway up-regulates NF-kappa B activity in melanoma cells. J Biol Chem 277, 7920-7928, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 7920-7928
    • Dhawan, P.1    Richmond, A.2
  • 37
    • 21544473172 scopus 로고    scopus 로고
    • Targeting STAT3 affects melanoma on multiple fronts
    • Kortylewski M, Jove R, and Yu H: Targeting STAT3 affects melanoma on multiple fronts. Cancer Metastasis Rev 24, 315-327, 2005.
    • (2005) Cancer Metastasis Rev , vol.24 , pp. 315-327
    • Kortylewski, M.1    Jove, R.2    Yu, H.3
  • 38
    • 73349128709 scopus 로고    scopus 로고
    • Integrated molecular and clinical analysis of AKT activation in metastatic melanoma
    • Davies MA, Stemke-Hale K, Lin E, Tellez C, Deng W, et al.: Integrated molecular and clinical analysis of AKT activation in metastatic melanoma. Clin Cancer Res 15, 7538-7546, 2009.
    • (2009) Clin Cancer Res , vol.15 , pp. 7538-7546
    • Davies, M.A.1    Stemke-Hale, K.2    Lin, E.3    Tellez, C.4    Deng, W.5


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