Personality trait predictors of placebo analgesia and neurobiological correlates

Neuropsychopharmacology

Volumn 38, Issue 4, 2013, Pages 639-646

  Peciña, Marta ^a,b   Azhar, Hamdan ^a,b   Love, Tiffany M ^a,b   Lu, Tingting ^a,c   Fredrickson, Barbara L ^d   Stohler, Christian S ^e   Zubieta, Jon Kar ^a,b,f  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

^d UNIVERSITY OF NORTH CAROLINA   (United States)

^e UNIVERSITY OF MARYLAND DENTAL SCHOOL   (United States)

^f UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

cortisol; opioids; personality; placebo; resilience; stress

Indexed keywords

HYDROCORTISONE; MU OPIATE RECEPTOR; OPIATE; PLACEBO;

ADULT; AMYGDALOID NUCLEUS; ANALGESIA; ANTERIOR CINGULATE; ARTICLE; CLINICAL TRIAL (TOPIC); CONTROLLED STUDY; FEMALE; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INSULA; MALE; MOLECULAR IMAGING; NEUROTRANSMISSION; NUCLEUS ACCUMBENS; ORBITAL CORTEX; PERIAQUEDUCTAL GRAY MATTER; PERSONALITY; PLACEBO EFFECT; PRIORITY JOURNAL;

ADULT; ANALGESIA; BRAIN; FEMALE; FORECASTING; HUMANS; HYDROCORTISONE; MALE; PAIN MEASUREMENT; PERSONALITY; PERSONALITY TESTS; PLACEBO EFFECT; YOUNG ADULT;

EID: 84873714753     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2012.227     Document Type: Article

References (54)

1. Bingel U, Lorenz J, Schoell E, Weiller C, Buchel C (2006). Mechanisms of placebo analgesia: rACC recruitment of a subcortical antinociceptive network. Pain 120: 8-15.
2. Block J, Kremen AM (1996). IQ and ego-resiliency: conceptual and empirical connections and separateness. J Pers Soc Psycol 70: 349-361.
3. Bruehl S, Burns JW, Chung OY, Chont M (2009). Pain-related effects of trait anger expression: neural substrates and the role of endogenous opioid mechanisms. Neurosci Biobehav Rev 33: 475-491.
4. Buckholtz JW, Treadway MT, Cowan RL, Woodward ND, Li R, Ansari MS et al (2010). Dopaminergic network differences in human impulsivity. Science 329: 532.
5. Bujdoso E, Jaszberenyi M, Tomboly C, Toth G, Telegdy G (2001). Behavioral and neuroendocrine actions of endomorphin-2. Peptides 22: 1459-1463.
6. Burns JW, Bruehl S, Chung OY, Magid E, Chont M, Goodlad JK et al (2009). Endogenous opioids may buffer effects of anger arousal on sensitivity to subsequent pain. Pain 146: 276-282.
7. Carver CS, White TL (1994). Behavioral inhibition, behavioral activation, and affective responses to impending reward and punishment: the BIS/BAS Scales. J Pers Soc Psycol 67: 319-333.
8. Charney DS (2004). Psychobiological mechanisms of resilience and vulnerability: implications for successful adaptation to extreme stress. Am J Psychiatry 161: 195-216.
9. Colloca L, Benedetti F (2009). Placebo analgesia induced by social observational learning. Pain 144: 28-34.
10. Costa P, McRae R (1992a). Normal personality assessment in clinical plactice: the NEO Personality Inventory. Psychol Assessment 4: 5-13.
11. Costa PT, McCrae RR (1992b). Revised NEO Personality Inventory (NEO-PI-R) and NEO Five-Factor Inventory professional manual. Psychological Assessment Resources: Odessa, FL.
12. Danziger N, Faillenot I, Peyron R (2009). Can we share a pain we never felt? Neural correlates of empathy in patients with congenital insensitivity to pain. Neuron 61: 203-212.
13. de la Fuente-Fernandez R, Ruth TJ, Sossi V, Schulzer M, Calne DB, Stoessl AJ (2001). Expectation and dopamine release: mechanism of the placebo effect in Parkinson's disease. Science 293: 1164-1166.
14. Feder A, Nestler EJ, Charney DS (2009). Psychobiology and molecular genetics of resilience. Nat Rev Neurosci 10: 446-457.
15. Fredrickson BL, Tugade MM, Waugh CE, Larkin GR (2003). What good are positive emotions in crises? A prospective study of resilience and emotions following the terrorist attacks on the United States on September 11th, 2001. J Pers Soc Psychol 84: 365-376.
16. Geers AL, Wellman JA, Fowler SL, Helfer SG, France CR (2010). Dispositional optimism predicts placebo analgesia. J Pain 11: 1165-1171.
17. Graziano WG, Habashi MM, Sheese BE, Tobin RM (2007). Agreeableness, empathy, and helping: a person x situation perspective. J Pers Soc Psychol 93: 583-599.
18. Hrobjartsson A, Gotzsche PC (2001). Is the placebo powerless? An analysis of clinical trials comparing placebo with no treatment. N Engl J Med 344: 1594-1602.
19. Jackson RV, Grice JE, Jackson AJ, Hockings GI (1990). Naloxoneinduced ACTH release in man is inhibited by clonidine. Clin Exp Pharmacol Physiol 17: 179-184.
20. Kelley JM, Lembo AJ, Ablon JS, Villanueva JJ, Conboy LA, Levy R et al (2009). Patient and practitioner influences on the placebo effect in irritable bowel syndrome. Psychosom Med 71: 789-797.
21. Keyes CLM (1998). Social well-being. Soc Psychol Quart 61: 121-140.
22. Kirsch I (1985). Response expectancy as a determinant of experience and behavior. Am Psychol 40: 1189-1202.
23. Krishnan V, Han MH, Graham DL, Berton O, Renthal W, Russo SJ et al (2007). Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions. Cell 131: 391-404.
24. Lasagna L, Mosteller F, Von Felsinger JM, Beecher HK (1954). A study of the placebo response. Am J Med 16: 770-779.
25. Le Cao KA, Rossouw D, Robert-Granie C, Besse P (2008). A sparse PLS for variable selection when integrating omics data. Stat Appl Genet Mol Biol 7: Article 35.
26. Leknes S, Tracey I (2008). A common neurobiology for pain and pleasure. Nat Rev Neurosci 9: 314-320.
27. Liberman R (1962). An analysis of the placebo phenomenon. J Chronic Dis 15: 761-783.
28. Love TM, Stohler CS, Zubieta JK (2009). Positron emission tomography measures of endogenous opioid neurotransmission and impulsiveness traits in humans. Arch Gen Psychiatry 66: 1124-1134.
29. Mackenbach JP (2005). On the survival of the altruistic trait in medicine: is there a link with the placebo effect? J Clin Epidemiol 58: 433-435.
30. Maitra S, Yan Y (2008). Principle component analysis and partial least squares: two dimension reduction techniques for regression. CAS Casualty Actuarial Society 2008 Discussion Paper Program.
31. Martin del Campo AF, Dowson JH, Herbert J, Paykel ES (1994). Effects of naloxone on diurnal rhythms in mood and endocrine function: a dose-response study in man. Psychopharmacology 114: 583-590.
32. Melzack R, Torgerson WS (1971). On the language of pain. Anesthesiology 34: 50-59.
33. Morton DL, Watson A, El-Deredy W, Jones AK (2009). Reproducibility of placebo analgesia: Effect of dispositional optimism. Pain 146: 194-198.
34. Pavot W, Diener E, Colvin CR, Sandvik E (1991). Further validation of the satisfaction with life scale: evidence for the cross-method convergence of well-being measures. J Pers Assess 57: 149-161.
35. Quilty LC, De Fruyt F, Rolland JP, Kennedy SH, Rouillon PF, Bagby RM (2008). Dimensional personality traits and treatment outcome in patients with major depressive disorder. J Affect Disord 108: 241-250.
36. Quilty LC, Sellbom M, Tackett JL, Bagby RM (2009). Personality trait predictors of bipolar disorder symptoms. Psychiatry Res 169: 159-163.
37. Reske M, Paulus MP (2008). Predicting treatment outcome in stimulant dependence. Ann N Y Acad Sci 1141: 270-283.
38. Rilling J, Gutman D, Zeh T, Pagnoni G, Berns G, Kilts C (2002). A neural basis for social cooperation. Neuron 35: 395-405.
39. Scheier MF, Carver CS, Bridges MW (1994). Distinguishing optimism from neuroticism (and trait anxiety, self-mastery, and self-esteem): a reevaluation of the Life Orientation Test. J Pers Soc Psychol 67: 1063-1078.
40. Schweinhardt P, Seminowicz DA, Jaeger E, Duncan GH, Bushnell MC (2009). The anatomy of the mesolimbic reward system: a link between personality and the placebo analgesic response. J Neurosci 29: 4882-4887.
41. Scott DJ, Stohler CS, Egnatuk CM, Wang H, Koeppe RA, Zubieta JK (2007). Individual differences in reward responding explain placebo-induced expectations and effects. Neuron 55: 325-336.
42. Scott DJ, Stohler CS, Egnatuk CM, Wang H, Koeppe RA, Zubieta JK (2008). Placebo and nocebo effects are defined by opposite opioid and dopaminergic responses. Arch Gen Psychiatry 65: 220-231.
43. Sim LJ, Joseph SA (1991). Arcuate nucleus projections to brainstem regions which modulate nociception. J Chem Neuroanat 4: 97-109.
44. Spielberg CD (1983). Manual for the State-Trait Anxiety Inventory (Form Y). Consulting Psychologist Press, Inc: Palo Alto.
45. Vythilingam M, Nelson EE, Scaramozza M, Waldeck T, Hazlett G, Southwick SM et al (2009). Reward circuitry in resilience to severe trauma: an fMRI investigation of resilient special forces soldiers. Psychiatry Res 172: 75-77.
46. Wager TD, Rilling JK, Smith EE, Sokolik A, Casey KL, Davidson RJ et al (2004). Placebo-induced changes in FMRI in the anticipation and experience of pain. Science 303: 1162-1167.
47. Wager TD, Scott DJ, Zubieta JK (2007). Placebo effects on human mu-opioid activity during pain. Proc Natl Acad Sci USA 104: 11056-11061.
48. Watamura SE, Donzella B, Kertes DA, Gunnar MR (2004). Developmental changes in baseline cortisol activity in early childhood: relations with napping and effortful control. Dev Psychobiol 45: 125-133.
49. Watson D, Clark LA, Tellegen A (1988). Development and validation of brief measures of positive and negative affect: the PANAS scales. J Pers Soc Psychol 54: 1063-1070.
50. Wold H (1966). Estimation fo principal components and related models by iterative least squares. In: Krishnaiah PR (Ed) (Mulitvariate Analysis Academic Press: New York39: 1-420.
51. Wold S, Sjostrom M, Eriksson L (2001). PLS-regression: a basic tool of chemometrics. Chemometr Intell Lab Syst 58: 109-130.
52. Zhou Z, Zhu G, Hariri AR, Enoch MA, Scott D, Sinha R et al (2008). Genetic variation in human NPY expression affects stress response and emotion. Nature 452: 997-1001.
53. Zubieta JK, Bueller JA, Jackson LR, Scott DJ, Xu Y, Koeppe RA et al (2005). Placebo effects mediated by endogenous opioid activity on mu-opioid receptors. J Neurosci 25: 7754-7762.
54. Zubieta JK, Heitzeg MM, Smith YR, Bueller JA, Xu K, Xu Y et al (2003). COMT val158met genotype affects mu-opioid neurotransmitter responses to a pain stressor. Science 299: 1240-1243.