Synthesis and biological evaluation of phosphonate analogues of nevirapine

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 5, 2013, Pages 1493-1497

  Parrish, Jay ^a   Tong, Leah ^a   Wang, Michael ^a   Chen, Xiaowu ^a   Lansdon, Eric B ^a   Cannizzaro, Carina ^a   Zheng, Xubin ^a   Desai, Manoj C ^a   Xu, Lianhong ^a  

^a GILEAD SCIENCES   (United States)

Author keywords

HIV; NNRTI; Non nucleoside reverse transcriptase inhibitors; Reverse transcriptase

Indexed keywords

EFAVIRENZ; NEVIRAPINE; PHOSPHONIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; DOG; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG HALF LIFE; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; MALE; NONHUMAN; STRUCTURE ACTIVITY RELATION; VIRUS REPLICATION; WILD TYPE;

HIV INFECTIONS; HIV-1; HUMANS; NEVIRAPINE; ORGANOPHOSPHONATES; REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84873711428     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.12.049     Document Type: Article

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