Novel nevirapine-like inhibitors with improved activity against NNRTI-resistant HIV: 8-Heteroarylthiomethyldipyridodiazepinone derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 3, 2004, Pages 739-742

  Yoakim, C ^a   Bonneau, P R ^a   Deziel R ^a   Doyon, L ^a   Duan, J ^a   Guse, I ^a   Landry, S ^a   Malenfant, E ^a   Naud, J ^a   Ogilvie, W W ^a   O'Meara, J A ^a   Plante, R ^a   Simoneau, B ^a   Thavonekham, B ^a   Bos M ^a   Cordingley, M G ^a  

^a BOEHRINGER INGELHEIM CANADA LTD   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; ASPARAGINE; CYSTEINE; DIAZEPINE DERIVATIVE; LYSINE; METHYL GROUP; NEVIRAPINE; PICOLINE DERIVATIVE; RNA DIRECTED DNA POLYMERASE INHIBITOR; TYROSINE;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG METABOLISM; DRUG SCREENING; DRUG STABILITY; DRUG SYNTHESIS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN TISSUE; LIVER; MALE; MICROSOME; MUTANT; NONHUMAN; RAT; WILD TYPE;

EID: 1642452639     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2003.11.049     Document Type: Article

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