Metallothionein blocks oxidative DNA damage in vitro

Archives of Toxicology

Volumn 87, Issue 2, 2013, Pages 311-321

  Qu, Wei ^a   Pi, Jingbo ^b   Waalkes, Michael P ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b HAMNER INSTITUTES FOR HEALTH SCIENCES   (United States)

Author keywords

Cadmium; Cancer; DNA; Metallothionein; Oxidative damage

Indexed keywords

CADMIUM; CELL DNA; GLUTATHIONE TRANSFERASE A2; HEME OXYGENASE 1; HYDROGEN PEROXIDE; METALLOTHIONEIN I; METALLOTHIONEIN II; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2;

ANALYTIC METHOD; ANIMAL CELL; ARTICLE; CELL PROTECTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA DAMAGE; GENE EXPRESSION; GENETIC TRANSFECTION; GSTALPHA2 GENE; HO 1 GENE; IN VITRO STUDY; LC 50; LETHALITY; MOUSE; MRP1 GENE; MRP2 GENE; NONHUMAN; NULL CELL; OXIDATIVE DNA DAMAGE; PRIORITY JOURNAL; PROTEIN FUNCTION; TOXICITY TESTING;

ANIMALS; CADMIUM CHLORIDE; CELL LINE; CELL SURVIVAL; DNA DAMAGE; EMBRYONIC STEM CELLS; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; GLUTATHIONE TRANSFERASE; HEME OXYGENASE-1; HYDROGEN PEROXIDE; ISOENZYMES; MEMBRANE PROTEINS; METALLOTHIONEIN; MICE; MICE, KNOCKOUT; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; OXIDANTS; OXIDATIVE STRESS; TRANSFECTION;

EID: 84873708861     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-012-0927-y     Document Type: Article

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