Astrocytic autoantibody of neuromyelitis optica (NMO-IgG) binds to aquaporin-4 extracellular loops, monomers, tetramers and high order arrays

Journal of Autoimmunity

Volumn 40, Issue 1, 2013, Pages 21-27

  Iorio, Raffaele ^a   Fryer, James P ^a   Hinson, Shannon R ^a   Fallier Becker, Petra ^c   Wolburg, Hartwig ^c   Pittock, Sean J ^a   Lennon, Vanda A ^a,b  

^a MAYO CLINIC   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

^c UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Autoimmunity; Epitopes; Freeze fracture electron microscopy

Indexed keywords

AQUAPORIN 4; EPITOPE; IMMUNOGLOBULIN G; MONOMER; SYNTHETIC PEPTIDE; TETRAMER;

ADOLESCENT; ADULT; AGED; ANTIGEN BINDING; ARTICLE; ASTROCYTE; CELL CULTURE; CELL MEMBRANE; CELL SURFACE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLUORESCENCE MICROSCOPY; FREEZE FRACTURE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IMMUNOREACTIVITY; MALE; MYELOOPTIC NEUROPATHY; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN LOCALIZATION; SENSITIVITY AND SPECIFICITY; SUPRAMOLECULAR CHEMISTRY; WESTERN BLOTTING;

AQUAPORIN 4; ASTROCYTES; AUTOANTIBODIES; CELL MEMBRANE; CELLS, CULTURED; CRYSTALLOGRAPHY, X-RAY; EPITOPES; FEMALE; HUMANS; MALE; NEUROMYELITIS OPTICA; RECOMBINANT FUSION PROTEINS;

EID: 84873704504     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2012.07.008     Document Type: Article

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