Identification of two major conformational aquaporin-4 epitopes for neuromyelitis optica autoantibody binding

Journal of Biological Chemistry

Volumn 286, Issue 11, 2011, Pages 9216-9224

  Pisani, Francesco ^a   Mastrototaro, Mauro ^a   Rossi, Andrea ^a   Nicchia, Grazia Paola ^a   Tortorella, Carla ^a   Ruggieri, Maddalena ^a   Trojano, Maria ^a   Frigeri, Antonio ^a   Svelto, Maria ^a  

^a UNIVERSITY OF BARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SEQUENCE; AQUAPORINS; AUTOANTIBODIES; BINDING CAPACITIES; CONFORMATIONAL CHANGE; EXTRACELLULAR LOOPS; IMMUNODOMINANT EPITOPES; MULTIPLE ALIGNMENT; ORTHOGONAL ARRAY; SECOND GROUP; SEQUENCE ANALYSIS; SUPRAMOLECULAR STRUCTURE; TETRAMERS;

AMINO ACIDS; OLIGOMERS;

ANTIGENS;

AQUAPORIN 4; EPITOPE;

AMINO ACID SEQUENCE; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; GENE DELETION; GENE MUTATION; GENE REARRANGEMENT; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MYELOOPTIC NEUROPATHY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; AQUAPORIN 4; AUTOANTIBODIES; EPITOPE MAPPING; EPITOPES; HELA CELLS; HUMANS; IMMUNOGLOBULIN G; MICE; NEUROMYELITIS OPTICA; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; RATS; SEQUENCE DELETION;

EID: 79953225158     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.123000     Document Type: Article

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