Efficient synthesis of 3H,3′H-spiro[benzofuran-2,1′- isobenzofuran]-3,3′-dione as novel skeletons specifically for influenza virus type B inhibition

European Journal of Medicinal Chemistry

Volumn 62, Issue , 2013, Pages 534-544

  Malpani, Yashwardhan ^a,b   Achary, Raghavendra ^a,b   Kim, So Yeon ^a   Jeong, Hee Chun ^a   Kim, Pilho ^a,b   Han, Soo Bong ^a   Kim, Meehyein ^a   Lee, Chong Kyo ^a,b   Kim, Jae Nyoung ^c   Jung, Young Sik ^a,b  

^a Korea Research Institute of Chemical Technology   (South Korea)

^b University of Science and Technology (UST)   (South Korea)

^c Chonnam National University   (South Korea)

Author keywords

Anti influenza virus type B; Antiviral activity; Iodine; Microwave; Spiro

Indexed keywords

3H,3'H SPIROL[BEZOFURAN 2,1' ISOBENZOFURAN] 3,3' DIONE DERIVATIVE; ADAMANTANE DERIVATIVE; ANTIVIRUS AGENT; LACTONE DERIVATIVE; PROTEIN M2; SPIRO COMPOUND; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; BIOLOGICAL ACTIVITY; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; GROWTH INHIBITION; HUMAN; HUMAN CELL; INFLUENZA VIRUS A; INFLUENZA VIRUS B; MICROWAVE IRRADIATION; VIRUS INHIBITION;

ANTIVIRAL AGENTS; BENZOFURANS; DOSE-RESPONSE RELATIONSHIP, DRUG; INFLUENZA B VIRUS; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84873701204     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.01.015     Document Type: Article

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